Roberta B Ness

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint Possible role of ovarian epithelial inflammation in ovarian cancer
    R B Ness
    R B Ness, Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA
    J Natl Cancer Inst 91:1459-67. 1999
  2. ncbi request reprint Endometriosis as a model for inflammation-hormone interactions in ovarian and breast cancers
    Roberta B Ness
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Room 513 Parran Hall, 130 DeSoto Street, Pittsburgh, PA 15261, USA
    Eur J Cancer 42:691-703. 2006
  3. ncbi request reprint Endometriosis and ovarian cancer: thoughts on shared pathophysiology
    Roberta B Ness
    Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, The University of Pittsburgh Cancer Institute, Pittsburgh, PA 15261, USA
    Am J Obstet Gynecol 189:280-94. 2003
  4. ncbi request reprint Infertility, fertility drugs, and ovarian cancer: a pooled analysis of case-control studies
    Roberta B Ness
    University of Pittsburgh School of Public Health, Pittsburgh, PA 15261, USA
    Am J Epidemiol 155:217-24. 2002
  5. ncbi request reprint Hormonal and barrier contraception and risk of upper genital tract disease in the PID Evaluation and Clinical Health (PEACH) study
    R B Ness
    University of Pittsburgh, Graduate School of Public Health, 130 DeSoto St, Pittsburgh, PA 15261, USA
    Am J Obstet Gynecol 185:121-7. 2001
  6. ncbi request reprint Salary equity among male and female internists in Pennsylvania
    R B Ness
    Graduate School of Public Health, University of Pittsburgh, University of Pittsburgh Medical Center, Pennsylvania 15261, USA
    Ann Intern Med 133:104-10. 2000
  7. ncbi request reprint Risk of ovarian cancer in relation to estrogen and progestin dose and use characteristics of oral contraceptives. SHARE Study Group. Steroid Hormones and Reproductions
    R B Ness
    Graduate School of Public Health, University of Pittsburgh, PA 15261, USA
    Am J Epidemiol 152:233-41. 2000
  8. pmc Do short-term markers of treatment efficacy predict long-term sequelae of pelvic inflammatory disease?
    Gail M Trautmann
    University of Pittsburgh School of Public Health, Pittsburgh, PA 15261, USA
    Am J Obstet Gynecol 198:30.e1-7. 2008
  9. pmc Racial variation in toll-like receptor variants among women with pelvic inflammatory disease
    Brandie D Taylor
    Department of Epidemiology, University of Pittsburgh, 130 DeSoto St, 513 Parran Hall, Pittsburgh, PA 15261, USA
    J Infect Dis 207:940-6. 2013
  10. pmc Parity and cardiovascular disease risk among older women: how do pregnancy complications mediate the association?
    Janet M Catov
    University of Pittsburgh, Department of Obstetrics, Gynecology and Reproductive Sciences, Pittsburgh PA 15213, USA
    Ann Epidemiol 18:873-9. 2008

Collaborators

Detail Information

Publications96

  1. ncbi request reprint Possible role of ovarian epithelial inflammation in ovarian cancer
    R B Ness
    R B Ness, Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA
    J Natl Cancer Inst 91:1459-67. 1999
    ..The possibility that inflammation is a pathophysiologic contributor to the development of ovarian cancer suggests a directed approach to future research..
  2. ncbi request reprint Endometriosis as a model for inflammation-hormone interactions in ovarian and breast cancers
    Roberta B Ness
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Room 513 Parran Hall, 130 DeSoto Street, Pittsburgh, PA 15261, USA
    Eur J Cancer 42:691-703. 2006
    ..Moreover, treatments for endometriosis may require consideration of the impact on long-term cancer risk...
  3. ncbi request reprint Endometriosis and ovarian cancer: thoughts on shared pathophysiology
    Roberta B Ness
    Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, The University of Pittsburgh Cancer Institute, Pittsburgh, PA 15261, USA
    Am J Obstet Gynecol 189:280-94. 2003
    ..Endometriosis appears to predispose to ovarian cancer. How this may occur has been little discussed...
  4. ncbi request reprint Infertility, fertility drugs, and ovarian cancer: a pooled analysis of case-control studies
    Roberta B Ness
    University of Pittsburgh School of Public Health, Pittsburgh, PA 15261, USA
    Am J Epidemiol 155:217-24. 2002
    ..10, 2.71) and unknown cause of infertility (OR = 1.19, 95% CI: 1.00, 1.40) increased cancer risk. These data suggest a role for specific biologic causes of infertility, but not for fertility drugs in overall risk for ovarian cancer...
  5. ncbi request reprint Hormonal and barrier contraception and risk of upper genital tract disease in the PID Evaluation and Clinical Health (PEACH) study
    R B Ness
    University of Pittsburgh, Graduate School of Public Health, 130 DeSoto St, Pittsburgh, PA 15261, USA
    Am J Obstet Gynecol 185:121-7. 2001
    ..Among women diagnosed with pelvic inflammatory disease, we examined the associations between hormonal or barrier methods of contraception and upper genital tract infection or inflammation...
  6. ncbi request reprint Salary equity among male and female internists in Pennsylvania
    R B Ness
    Graduate School of Public Health, University of Pittsburgh, University of Pittsburgh Medical Center, Pennsylvania 15261, USA
    Ann Intern Med 133:104-10. 2000
    ..Historically, inequities have existed between male and female physicians in professional advancement, but evidence has suggested that disparities in salary are resolving...
  7. ncbi request reprint Risk of ovarian cancer in relation to estrogen and progestin dose and use characteristics of oral contraceptives. SHARE Study Group. Steroid Hormones and Reproductions
    R B Ness
    Graduate School of Public Health, University of Pittsburgh, PA 15261, USA
    Am J Epidemiol 152:233-41. 2000
    ..5, 95% confidence interval: 0.3, 0.6) that was identical to that for high-estrogen/high-progestin pills (odds ratio = 0.5, 95% confidence interval: 0.3, 0.7)...
  8. pmc Do short-term markers of treatment efficacy predict long-term sequelae of pelvic inflammatory disease?
    Gail M Trautmann
    University of Pittsburgh School of Public Health, Pittsburgh, PA 15261, USA
    Am J Obstet Gynecol 198:30.e1-7. 2008
    ....
  9. pmc Racial variation in toll-like receptor variants among women with pelvic inflammatory disease
    Brandie D Taylor
    Department of Epidemiology, University of Pittsburgh, 130 DeSoto St, 513 Parran Hall, Pittsburgh, PA 15261, USA
    J Infect Dis 207:940-6. 2013
    ..Racial disparities exist in gynecological diseases. Variations in Toll-like receptor (TLR) genes may alter signaling following microbial recognition...
  10. pmc Parity and cardiovascular disease risk among older women: how do pregnancy complications mediate the association?
    Janet M Catov
    University of Pittsburgh, Department of Obstetrics, Gynecology and Reproductive Sciences, Pittsburgh PA 15213, USA
    Ann Epidemiol 18:873-9. 2008
    ..To determine whether parity is associated with increased risk of cardiovascular disease (CVD) after accounting for perinatal complications...
  11. ncbi request reprint Anthropometry and the risk of epithelial ovarian cancer
    Julia B Greer
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Cancer 106:2247-57. 2006
    ..Because factors such as oral contraceptive (OC), hormone therapy (HT), and parity may affect weight and hormone levels, the associations were examined in women with and without these characteristics...
  12. ncbi request reprint Bacterial vaginosis (BV) and the risk of incident gonococcal or chlamydial genital infection in a predominantly black population
    Roberta B Ness
    University of Pittsburgh, PA 15261, USA
    Sex Transm Dis 32:413-7. 2005
    ..The objective of this study was to assess in prospective data whether bacterial vaginosis (BV) is associated with gonococcal/chlamydial cervicitis...
  13. ncbi request reprint Douching, pelvic inflammatory disease, and incident gonococcal and chlamydial genital infection in a cohort of high-risk women
    Roberta B Ness
    University of Pittsburgh, Department of Epidemiology, Graduate School of Public Health, Room A530 Crabtree Hall, 130 DeSoto Street, Pittsburgh, PA 15261, USA
    Am J Epidemiol 161:186-95. 2005
    ..These data do not support an association between douching and development of PID or gonococcal/chlamydial genital infection among predominantly young, African-American women...
  14. ncbi request reprint Chlamydia antibodies, chlamydia heat shock protein, and adverse sequelae after pelvic inflammatory disease: the PID Evaluation and Clinical Health (PEACH) Study
    Roberta B Ness
    Department of Epidemiology, University of Pittsburgh, PA 15261, USA
    Sex Transm Dis 35:129-35. 2008
    ..Among women with pelvic inflammatory disease (PID), we assessed the associations among antibodies to Chlamydia trachomatis elementary bodies (EB), antibodies to chlamydia heat shock protein (Chsp60), rates of pregnancy, and PID recurrence...
  15. pmc Interactions between smoking and weight in pregnancies complicated by preeclampsia and small-for-gestational-age birth
    Roberta B Ness
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Am J Epidemiol 168:427-33. 2008
    ..Obesity eliminated the inverse association between smoking and preeclampsia but did not substantially alter the positive association between smoking and SGA. A possible unifying biologic explanation is discussed in this paper...
  16. doi request reprint Influence of estrogen plus testosterone supplementation on breast cancer
    Roberta B Ness
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Arch Intern Med 169:41-6. 2009
    ..We sought to examine the relationship between the use of estrogen plus testosterone (E + T) therapy (esterified estradiol plus methyltestosterone) and the occurrence of breast cancer...
  17. ncbi request reprint Predictors of chronic pelvic pain in an urban population of women with symptoms and signs of pelvic inflammatory disease
    Catherine L Haggerty
    University of Pittsburgh, Department of Epidemiology, Pittsburgh, Pennsylvania 15261, USA
    Sex Transm Dis 32:293-9. 2005
    ..The objective of this study was to assess the risk profile for chronic pelvic pain (CPP) after pelvic inflammatory disease (PID)...
  18. ncbi request reprint Association between allelic variants in cytokine genes and preeclampsia
    Catherine L Haggerty
    University of Pittsburgh, Magee Womens Research Institute, PA 15261, USA
    Am J Obstet Gynecol 193:209-15. 2005
    ..The purpose of this study was to examine the relationship between cytokine genotypes and preeclampsia...
  19. pmc Clinical presentation of Mycoplasma genitalium Infection versus Neisseria gonorrhoeae infection among women with pelvic inflammatory disease
    Vanessa L Short
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Clin Infect Dis 48:41-7. 2009
    ..The characteristics of nongonococcal, nonchlamydial PID have not been well described. Our objective was to examine the characteristics of Mycoplasma genitalium infection among women with clinically suspected PID...
  20. ncbi request reprint The absence of interaction between drug metabolizing enzyme genotypes and maternal lifestyle factors on glycophorin A somatic mutation frequency levels in newborns
    Tomoko Nukui
    Center for Clinical Pharmacology, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15219, USA
    Pharmacogenet Genomics 16:129-38. 2006
    ..The observed variation in newborn GPA frequency might be due to either environmental factors not assessed in this study or inter-individual differences in alternative metabolic or DNA repair pathways...
  21. pmc Condom use and the risk of recurrent pelvic inflammatory disease, chronic pelvic pain, or infertility following an episode of pelvic inflammatory disease
    Roberta B Ness
    University of Pittsburgh, Graduate School of Public Health, 130 DeSoto St, A530 Crabtree Hall, Pittsburgh, PA 15261, USA
    Am J Public Health 94:1327-9. 2004
    ..Consistent condom use (about 60% of encounters) at baseline also reduced these risks, after adjustment for confounders, by 30% to 60%. Self-reported persistent and consistent condom use was associated with lower rates of PID sequelae...
  22. pmc Preeclampsia risk and angiotensinogen polymorphisms M235T and AGT -217 in African American and Caucasian women
    Laura D Jenkins
    Magee Women s Research Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Reprod Sci 15:696-701. 2008
    ..The authors investigated the frequency of M235T and AGT -217 in Caucasian and African American women with and without preeclampsia...
  23. ncbi request reprint Association between infant birth weight and maternal cardiovascular risk factors in the health, aging, and body composition study
    Janet M Catov
    Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15261, USA
    Ann Epidemiol 17:36-43. 2007
    ....
  24. ncbi request reprint Association of periconceptional multivitamin use and risk of preterm or small-for-gestational-age births
    Janet M Catov
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Am J Epidemiol 166:296-303. 2007
    ..Study results indicate lower rates of severe preterm births and extreme SGA in women who report periconceptional vitamin use, although these should be considered cautiously until replicated...
  25. pmc Can known risk factors explain racial differences in the occurrence of bacterial vaginosis?
    Roberta B Ness
    University of Pittsburgh, Graduate School of Public Health, Magee Womens Hospital, Pittsburgh, Pennsylvania 15261, USA
    J Natl Med Assoc 95:201-12. 2003
    ..Black women are more likely to have bacterial vaginosis (BV) than are non-Hispanic white women. We examined whether this disparity can be explained by racial differences in known BV risk factors...
  26. ncbi request reprint Maternal leptin across pregnancy in women with small-for-gestational-age infants
    Janet M Catov
    Department of Epidemiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
    Am J Obstet Gynecol 196:558.e1-8. 2007
    ..We hypothesized that women with small-for-gestational-age (SGA) neonates would have lower concentrations of leptin compared to women with appropriately grown infants (AGA)...
  27. ncbi request reprint Cost-effectiveness of alternative outpatient pelvic inflammatory disease treatment strategies
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Sex Transm Dis 34:960-6. 2007
    ..Effectiveness differences between outpatient pelvic inflammatory disease (PID) treatment regimens are uncertain, but significant differences in cost exist...
  28. ncbi request reprint Inflammation and triglycerides partially mediate the effect of prepregnancy body mass index on the risk of preeclampsia
    Lisa M Bodnar
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Am J Epidemiol 162:1198-206. 2005
    ..Inflammation was a more important mediator than triglycerides. These findings suggest that approximately one third of the total effect of body mass index on preeclampsia risk is mediated through inflammation and triglyceride levels...
  29. ncbi request reprint Oral contraceptive use, reproductive history, and risk of epithelial ovarian cancer in women with and without endometriosis
    Francesmary Modugno
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, and University of Pittsburgh Cancer Institute, Pittsburgh, PA 15261, USA
    Am J Obstet Gynecol 191:733-40. 2004
    ..We investigated whether the odds ratios for ovarian cancer that were associated with oral contraceptive use, childbearing, hysterectomy, and tubal ligation differ among women with and without endometriosis...
  30. pmc Cigarette smoke exposure and angiogenic factors in pregnancy and preeclampsia
    Arun Jeyabalan
    Magee Womens Research Institute and Foundation, Pittsburgh, Pennsylvania, USA
    Am J Hypertens 21:943-7. 2008
    ....
  31. ncbi request reprint Inflammation and dyslipidemia related to risk of spontaneous preterm birth
    Janet M Catov
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Am J Epidemiol 166:1312-9. 2007
    ..The results indicate that some metabolic factors together with inflammation may be related to the risk of sPTB...
  32. ncbi request reprint Effectiveness of treatment strategies of some women with pelvic inflammatory disease: a randomized trial
    Roberta B Ness
    University of Pittsburgh, Graduate School of Public Health, Pittsburgh, Pennsylvania 15261, USA
    Obstet Gynecol 106:573-80. 2005
    ..We assessed whether outpatient is as effective as inpatient treatment in relevant age, race, and clinical subgroups of women with PID...
  33. ncbi request reprint A cluster analysis of bacterial vaginosis-associated microflora and pelvic inflammatory disease
    Roberta B Ness
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Am J Epidemiol 162:585-90. 2005
    ..77, 95% confidence interval: 1.11, 69.2). When identified by microbial culture, a combination of BV-related microorganisms significantly elevated the risk of acquiring PID...
  34. pmc Mycoplasma genitalium among young, urban pregnant women
    Vanessa L Short
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Infect Dis Obstet Gynecol 2010:984760. 2010
    ..As the consequences of Mycoplasma genitalium in pregnant women are unknown, we examined the relationship between prenatal M. genitalium infection and SAB...
  35. pmc Microbial correlates of delayed care for pelvic inflammatory disease
    Brandie D Taylor
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Sex Transm Dis 38:434-8. 2011
    ..We studied the microbial correlates of time to care and long-term outcomes among pelvic inflammatory disease (PID) patients, as delayed care may increase the risk for reproductive sequelae...
  36. pmc Aspirin, nonaspirin nonsteroidal anti-inflammatory drug, and acetaminophen use and risk of invasive epithelial ovarian cancer: a pooled analysis in the Ovarian Cancer Association Consortium
    Britton Trabert
    Affiliations of authors Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD BT, Lab, NW University of Texas School of Public Health, Houston, TX RBN Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA WL Channing Division of Network Medicine MAM, EMP and Obstetrics and Gynecology Epidemiology Center DWC, KLT, Brigham and Women s Hospital and Harvard Medical School, Boston, MA Department of Epidemiology, Harvard School of Public Health, Boston, MA MAM, EMP, DWC, KLT Department of Health Sciences Research, Division of Epidemiology, Mayo Clinic, Rochester, MN ELG Queensland Institute of Medical Research, Brisbane, Australia PMW, CMN, SJJ, Australian Ovarian Cancer Study Group, the Australian Cancer Study Ovarian Cancer Peter MacCallum Cancer Centre, East Melbourne, Australia Australian Ovarian Cancer Study Group Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT HAR Program in Epidemiology, Fred Hutchinson Cancer Research Center, Seattle, WA MAR, Brazil
    J Natl Cancer Inst 106:djt431. 2014
    ..Epidemiologic studies analyzing aspirin, nonaspirin nonsteroidal anti-inflammatory drug (NSAID), and acetaminophen use and ovarian cancer risk have been inconclusive...
  37. pmc The impact of menopause on health-related quality of life: results from the STRIDE longitudinal study
    Rachel Hess
    Division of General Internal Medicine, University of Pittsburgh School of Medicine, 230 McKee Place, Suite 600, Pittsburgh, PA 15213, USA
    Qual Life Res 21:535-44. 2012
    ..We examine the impact of menopausal status, beyond menopausal symptoms, on health-related quality of life (HRQoL)...
  38. ncbi request reprint Uric acid concentrations in early pregnancy among preeclamptic women with gestational hyperuricemia at delivery
    Robert W Powers
    Magee Womens Research Institute, Pittsburgh, PA 15213, USA
    Am J Obstet Gynecol 194:160. 2006
    ..We investigated changes in serum uric acid across pregnancy in women with gestational hyperuricemia at delivery, with and without preeclampsia, compared with normal pregnant and women with preeclampsia without gestational hyperuricemia...
  39. ncbi request reprint Why women douche and why they may or may not stop
    Roberta B Ness
    University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Sex Transm Dis 30:71-4. 2003
    ..Although douching is common, it is a potentially harmful habit...
  40. ncbi request reprint Bacterial vaginosis and risk of pelvic inflammatory disease
    Roberta B Ness
    University of Pittsburgh, Graduate School of Public Health, Magee Womens Hospital and Research Institute, Pittsburgh, PA 15261, USA
    Obstet Gynecol 104:761-9. 2004
    ..Bacterial vaginosis commonly is found in women with pelvic inflammatory disease (PID), but it is unclear whether bacterial vaginosis leads to incident PID...
  41. ncbi request reprint Quality of life utilities for pelvic inflammatory disease health states
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Sex Transm Dis 35:307-11. 2008
    ..Utilities for PID could have important implications on the cost-effectiveness of interventions to prevent and manage this disease...
  42. ncbi request reprint Vaginal douching and development of bacterial vaginosis among women with normal and abnormal vaginal microflora
    Katherine B Hutchinson
    University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Sex Transm Dis 34:671-5. 2007
    ..To evaluate the relationship between douching and bacterial vaginosis (BV) among women with and without prior abnormal vaginal flora...
  43. ncbi request reprint Maternal leptin concentrations are similar in African Americans and Caucasians in normal pregnancy, preeclampsia and small-for-gestational-age infants
    Laura D Jenkins
    Magee Womens Research Institute, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Hypertens Pregnancy 26:101-9. 2007
    ..Differences in the frequency and severity of preeclampsia in African Americans cannot be explained by higher leptin concentrations...
  44. ncbi request reprint Associations among human leukocyte antigen (HLA) class II DQ variants, bacterial sexually transmitted diseases, endometritis, and fertility among women with clinical pelvic inflammatory disease
    Roberta B Ness
    Graduate School of Public Health and Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Sex Transm Dis 31:301-4. 2004
    ..We investigated associations between HLA class II DQ alleles, chlamydial and gonococcal cervicitis, endometritis, and infertility among women with pelvic inflammatory disease (PID)...
  45. pmc Chronic hypertension related to risk for preterm and term small for gestational age births
    Janet M Catov
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pittsburgh Pennsylvania, USA
    Obstet Gynecol 112:290-6. 2008
    ..To identify factors associated with SGA that may involve a placental pathogenesis, we related chronic hypertension and other maternal factors that may be markers of endothelial dysfunction to preterm compared with term SGA births...
  46. ncbi request reprint Uric acid is as important as proteinuria in identifying fetal risk in women with gestational hypertension
    James M Roberts
    Department of Obstetrics, Gynecology and Reproductive Sciences, Magee Womens Research Institute, University of Pittsburgh, Pittsburgh, PA, USA
    Hypertension 46:1263-9. 2005
    ..Hyperuricemia is at least as effective as proteinuria at identifying gestational hypertensive pregnancies at increased risk. Uric acid should be reexamined for clinical and research utility...
  47. ncbi request reprint Diagnosis and treatment of pelvic inflammatory disease
    Catherine L Haggerty
    University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA 15261, USA
    Womens Health (Lond Engl) 4:383-97. 2008
    ..Research comparing sequelae development by differing antimicrobial regimens is extremely limited, but will ultimately shape future treatment guidelines...
  48. pmc Variants in toll-like receptor 1 and 4 genes are associated with Chlamydia trachomatis among women with pelvic inflammatory disease
    Brandie D Taylor
    Department of Epidemiology, University of Pittsburgh, PA 15213, USA
    J Infect Dis 205:603-9. 2012
    ..Toll-like receptors (TLRs) are involved in the innate immune response. We examined whether TLR variants are associated with Chlamydia trachomatis infection among women with pelvic inflammatory disease (PID)...
  49. ncbi request reprint Short-term oral contraceptive use and the risk of epithelial ovarian cancer
    Julia B Greer
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    Am J Epidemiol 162:66-72. 2005
    ..Mediating factors may reflect endogenous hormone levels, OC metabolism, or OC bioactivity...
  50. ncbi request reprint Prepregnancy body mass index and the occurrence of severe hypertensive disorders of pregnancy
    Lisa M Bodnar
    Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania 15261, USA
    Epidemiology 18:234-9. 2007
    ..Prepregnancy overweight is a risk factor for mild preeclampsia and mild transient hypertension of pregnancy. Its association with severe subtypes of these disorders has received less attention...
  51. pmc C-reactive protein is elevated 30 years after eclamptic pregnancy
    Carl A Hubel
    Magee Womens Research Institute and Department of Obstetrics and Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, PA, USA
    Hypertension 51:1499-505. 2008
    ..The triad of inflammation, low HDL, and insulin resistance may elevate risk for both preeclampsia/eclampsia and cardiovascular disease in later life...
  52. ncbi request reprint Preterm delivery and later maternal cardiovascular disease risk
    Janet M Catov
    Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15261, USA
    Epidemiology 18:733-9. 2007
    ..Women who have delivered a preterm infant are at elevated risk for cardiovascular disease (CVD), but mechanisms for this association are not understood...
  53. ncbi request reprint Invited commentary: Timing and types of cardiovascular risk factors in relation to offspring birth weight
    Roberta B Ness
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Am J Epidemiol 166:1365-7. 2007
    ..Without all such time points, life course effects will remain only partially understood. It is hoped that studies such as the forthcoming National Children's Study will generate critical understanding of this issue...
  54. doi request reprint Urinary estrogen metabolites and breast cancer: a combined analysis of individual level data
    Cher M Dallal
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Int J Biol Markers 28:3-16. 2013
    ..This combined analysis of 5 published studies evaluates urinary 2-hydroxyestrone (2-OHE1), 16α-hydroxyestrone (16α-OHE1), and their ratio (2:16α-OHE1) in relation to breast cancer risk...
  55. ncbi request reprint Soluble fms-like tyrosine kinase 1 is increased in preeclampsia but not in normotensive pregnancies with small-for-gestational-age neonates: relationship to circulating placental growth factor
    Eiji Shibata
    Magee Womens Research Institute, University of Pittsburgh, 204 Craft Avenue, Pittsburgh, Pennsylvania 15213, USA
    J Clin Endocrinol Metab 90:4895-903. 2005
    ..However, the latter condition occurs without maternal vascular disease...
  56. pmc Prepregnancy lipids related to preterm birth risk: the coronary artery risk development in young adults study
    Janet M Catov
    Department of Obstetrics and Gynecology, University of Pittsburgh, 300 Halket Street, Pittsburgh, Pennsylvania 15213, USA
    J Clin Endocrinol Metab 95:3711-8. 2010
    ..Preterm birth is associated with maternal cardiovascular risk, but mechanisms are unknown...
  57. ncbi request reprint Diagnostic test characteristics of placental weight in the prediction of small-for-gestational-age neonates
    Roberta B Ness
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, and Magee Womens Research Institute, Pittsburgh, Pennsylvania 15261, USA
    J Reprod Med 52:793-800. 2007
    ..To assess the diagnostic test characteristics of placental weight as a clinical predictor of small-for-gestational-age (SGA) neonates...
  58. ncbi request reprint Risk of early or severe pre-eclampsia related to pre-existing conditions
    Janet M Catov
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Int J Epidemiol 36:412-9. 2007
    ..We estimated the population attributable fractions of severe or early PE associated with pre-existing conditions among nulliparous and multiparous women...
  59. ncbi request reprint Early pregnancy lipid concentrations and spontaneous preterm birth
    Janet M Catov
    Department of Epidemiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Am J Obstet Gynecol 197:610.e1-7. 2007
    ..Women who deliver preterm infants may be at increased risk for cardiovascular disease, perhaps related to dyslipidemia...
  60. ncbi request reprint The risk of preeclampsia rises with increasing prepregnancy body mass index
    Lisa M Bodnar
    Magee Womens Research Institute, Pittsburgh, PA, USA
    Ann Epidemiol 15:475-82. 2005
    ..To explore the dose-dependent relation between prepregnancy body mass index (BMI) and the risk of preeclampsia after adjusting for measured confounders...
  61. ncbi request reprint Endometritis does not predict reproductive morbidity after pelvic inflammatory disease
    Catherine L Haggerty
    University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA 15261, USA
    Am J Obstet Gynecol 188:141-8. 2003
    ..We investigated the association between endometritis and reproductive morbidity...
  62. ncbi request reprint Differential distribution of allelic variants in cytokine genes among African Americans and White Americans
    Roberta B Ness
    Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Am J Epidemiol 160:1033-8. 2004
    ..5-fold (95% CI: 1.8, 6.6) and 2.8-fold (95% CI: 1.6, 4.9) in African Americans. Cytokine genotypes found to be more common in African-American women were consistently those that up-regulate inflammation...
  63. ncbi request reprint Breast cancer risk factors and mammographic breast density in women over age 70
    Francesmary Modugno
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Breast Cancer Res Treat 97:157-66. 2006
    ..Breast density is a strong risk factor for breast cancer, but little is known about factors associated with breast density in women over 70...
  64. ncbi request reprint Maternal/newborn GSTT1 null genotype contributes to risk of preterm, low birthweight infants
    Tomoko Nukui
    Department of Medicine, The Center of Clinical Pharmacology, Pittsburgh, PA, USA
    Pharmacogenetics 14:569-76. 2004
    ..However, little is known about genetic susceptibility and possible interactions with cigarette smoking which may increase risk of these events...
  65. ncbi request reprint Bacterial vaginosis and anaerobic bacteria are associated with endometritis
    Catherine L Haggerty
    University of Pittsburgh, 130 DeSoto St, 516 Parran Hall, Pittsburgh, PA 15261, USA
    Clin Infect Dis 39:990-5. 2004
    ..Chlamydia trachomatis and/or Neisseria gonorrhoeae account for approximately one-third to one-half of pelvic inflammatory disease (PID) cases. Thus, up to 70% of cases have an unknown, nongonococcal/nonchlamydial microbial etiology...
  66. ncbi request reprint Shared and disparate components of the pathophysiologies of fetal growth restriction and preeclampsia
    Roberta B Ness
    Department of Epidemiology, University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA 15261, USA
    Am J Obstet Gynecol 195:40-9. 2006
    ..Among these women, the baby is affected by shallow placentation but the mother does not develop clinically apparent disease. This conceptualization provides a testable framework for future etiologic studies of preeclampsia and IUGR...
  67. ncbi request reprint Newest approaches to treatment of pelvic inflammatory disease: a review of recent randomized clinical trials
    Catherine L Haggerty
    University of Pittsburgh, Pittsburgh, PA 15261, USA
    Clin Infect Dis 44:953-60. 2007
    ..Although a handful of studies have shown that monotherapies for PID achieve high rates of clinical cure, the efficacy of these regimens in treating anaerobic PID and in preventing adverse reproductive sequelae is not fully elucidated...
  68. ncbi request reprint Variability of bacterial vaginosis over 6- to 12-month intervals
    Roberta B Ness
    University of Pittsburgh, Graduate School of Public Health, Pennsylvania, 15261, USA
    Sex Transm Dis 33:381-5. 2006
    ..To examine variability in bacterial vaginosis (BV) over 6- to 12-month intervals...
  69. ncbi request reprint Effectiveness of inpatient and outpatient treatment strategies for women with pelvic inflammatory disease: results from the Pelvic Inflammatory Disease Evaluation and Clinical Health (PEACH) Randomized Trial
    Roberta B Ness
    University of Pittsburgh, Graduate School of Public Health, PA 15261, USA
    Am J Obstet Gynecol 186:929-37. 2002
    ..Pelvic inflammatory disease (PID) is a common and morbid intraperitoneal infection. Although most women with pelvic inflammatory disease are treated as outpatients, the effectiveness of this strategy remains unproven...
  70. pmc Mycoplasma genitalium among women with nongonococcal, nonchlamydial pelvic inflammatory disease
    Catherine L Haggerty
    University of Pittsburgh, Pittsburgh, PA 15260, USA
    Infect Dis Obstet Gynecol 2006:30184. 2006
    ..We detected M genitalium in 7 (14%) of the women tested: 6 (12%) in cervical specimens and 4 (8%) in endometrial specimens. We conclude that M genitalium is prevalent in the endometrium of women with nongonococcal, nonchlamydial PID...
  71. ncbi request reprint Adherence to oral therapies in pelvic inflammatory disease
    Jacqueline Dunbar-Jacob
    School of Nursing, University of Pittsburgh, Pennsylvania 15261, USA
    J Womens Health (Larchmt) 13:285-91. 2004
    ..To assess adherence to oral therapies in pelvic inflammatory disease (PID)...
  72. ncbi request reprint Cigarette smoking and the risk of mucinous and nonmucinous epithelial ovarian cancer
    Francesmary Modugno
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 516A Parran Hall, 130 DeSoto Street, Pittsburgh, PA 15261, USA
    Epidemiology 13:467-71. 2002
    ..The association between cigarette smoking and ovarian cancer may vary according to the histologic type of tumor...
  73. ncbi request reprint Effect of smoking on uric acid and other metabolic markers throughout normal pregnancy
    Kristine Y Lain
    Magee Womens Research Institute and Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pennsylvania 15213, USA
    J Clin Endocrinol Metab 90:5743-6. 2005
    ..We compared several metabolic markers of the metabolic syndrome in healthy primigravid smokers and nonsmokers over normal pregnancy to explore mechanisms for the reduced risk of preeclampsia in smokers...
  74. pmc Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women
    Rachel T Palmieri
    Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    Cancer Epidemiol Biomarkers Prev 17:3567-72. 2008
    ..This analysis shows the importance of consortia, like the OCAC, in either confirming or refuting the validity of putative findings in studies with smaller sample sizes. (Cancer Epidemiol Biomarkers Prev 2008;17(12):3567-72)...
  75. doi request reprint Risk of sequelae after Chlamydia trachomatis genital infection in women
    Catherine L Haggerty
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15261, USA
    J Infect Dis 201:S134-55. 2010
    ..trachomatis infection; better tools to measure PID and tubal damage; and studies on the natural history of repeated chlamydial infections are needed...
  76. ncbi request reprint Intersections between adverse pregnancy outcomes
    Roberta B Ness
    University of Pittsburgh, Graduate School of Public Health, Room 517 Parran Hall, 130 DeSoto Street, Pittsburgh, PA 15261, USA
    Womens Health (Lond Engl) 1:245-51. 2005
    ..In this review, hyperimmune responsiveness to pregnancy is provided as one example of a process leading to a multitude of adverse impacts on healthy childbearing. Further research on reproductive failure as a spectrum is warranted...
  77. ncbi request reprint HPRT gene alterations in umbilical cord blood T-lymphocytes in newborns of mothers exposed to tobacco smoke during pregnancy
    Phouthone Keohavong
    Department of Environmental and Occupational Health, University of Pittsburgh, 3343 Forbes Avenue, Pittsburgh, PA 15260, USA
    Mutat Res 572:156-66. 2005
    ....
  78. ncbi request reprint Relations of gestational length and timing and type of incomplete pregnancy to ovarian cancer risk
    Gretchen L Gierach
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA, USA
    Am J Epidemiol 161:452-61. 2005
    ..80, 95% CI: 0.44, 1.47). These data do not support an independent association between incomplete pregnancies, either spontaneous or induced, and ovarian cancer risk...
  79. ncbi request reprint The consequences for human reproduction of a robust inflammatory response
    Roberta B Ness
    University of Pittsburgh, Graduate School of Public Health, Pittsburgh, Pennsylvania 15261, USA
    Q Rev Biol 79:383-93. 2004
    ..The hypothesis that immune hyperresponsiveness limits reproductive capacity suggests many avenues for research...
  80. ncbi request reprint Hormone replacement therapy formulations and risk of epithelial ovarian carcinoma
    Anita S Y Sit
    Graduate School of Public Health, University of Pittsburgh, Pennsylvania 15213, USA
    Gynecol Oncol 86:118-23. 2002
    ..The aim of the study is to evaluate the impact of various HRT formulations and their characteristics of use on the risk of epithelial ovarian carcinoma (EOC)...
  81. ncbi request reprint Gender of offspring and maternal ovarian cancer risk
    Gretchen L Gierach
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, University of Pittsburgh Cancer Institute, 3520 5th Avenue, Suite 510, Pittsburgh, PA 15213, USA
    Gynecol Oncol 101:476-80. 2006
    ..We sought to determine whether offspring gender, which differentially alters maternal hormonal milieu, may be associated with maternal ovarian cancer risk...
  82. ncbi request reprint Inflammation and endometrial cancer: a hypothesis
    Francesmary Modugno
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 516A Parran Hall, 130 DeSoto Street, Pittsburgh, PA 15261, USA
    Cancer Epidemiol Biomarkers Prev 14:2840-7. 2005
    ..A proinflammatory milieu can also directly increase estrogen production. Hence, inflammation may work in conjunction with or in addition to estrogen exposure in the development of endometrial cancer...
  83. ncbi request reprint Causal system modeling in chronic disease epidemiology: a proposal
    Roberta B Ness
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Ann Epidemiol 17:564-8. 2007
    ..In all of these ways, they have the capability to advance the science of epidemiology...
  84. ncbi request reprint Influence of the HIPAA Privacy Rule on health research
    Roberta B Ness
    University of Pittsburgh, Graduate School of Public Health, Pittsburgh, Pennsylvania 15261, USA
    JAMA 298:2164-70. 2007
    ..Anecdotal reports suggest that the Health Insurance Portability and Accountability Act Privacy Rule (HIPAA Privacy Rule) may be affecting health research in the United States...
  85. ncbi request reprint Family history of hypertension, heart disease, and stroke among women who develop hypertension in pregnancy
    Roberta B Ness
    University of Pittsburgh Graduate Scool of Public Health, and Magee Womens Research Institute, Pittsburgh, Pennsylvania 15261, USA
    Obstet Gynecol 102:1366-71. 2003
    ..To assess familial cardiovascular risk factors in women developing hypertension in pregnancy...
  86. pmc Male reproductive proteins and reproductive outcomes
    Roberta B Ness
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Am J Obstet Gynecol 198:620.e1-4. 2008
    ..We offer a clinical opinion that MRPs may have broad implications for successful reproduction, potentially involved in the composition of vaginal microflora, risks of preterm birth and preeclampsia, and success of assisted reproduction...
  87. ncbi request reprint Homocysteine and folic acid are inversely related in black women with preeclampsia
    Thelma E Patrick
    Magee Womens Research Institute, Pittsburgh, PA, USA
    Hypertension 43:1279-82. 2004
    ..Racial differences in diet, adherence to folic acid supplementation, or interactions of nutritional and maternal factors warrant further study by race and pregnancy status...
  88. ncbi request reprint Preferences for fertility in women with pelvic inflammatory disease
    Thomas J Songer
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Fertil Steril 81:1344-50. 2004
    ..To identify the value that women with pelvic inflammatory disease (PID) assign to the health impact of future infertility...
  89. ncbi request reprint Prediction of pelvic inflammatory disease among young, single, sexually active women
    Roberta B Ness
    Graduate School of Public Health, University of Pittsburgh, Pennsylvania 15261, USA
    Sex Transm Dis 33:137-42. 2006
    ..To assess prediction strategies for pelvic inflammatory disease (PID)...
  90. ncbi request reprint Family history of cancer, oral contraceptive use, and ovarian cancer risk
    Gail R Walker
    Sylvester Comprehensive Cancer Center, University of Miami School of Medicine, Florida, USA
    Am J Obstet Gynecol 186:8-14. 2002
    ....
  91. ncbi request reprint Preeclampsia and future cardiovascular disease: potential role of altered angiogenesis and insulin resistance
    Myles Wolf
    Renal Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Clin Endocrinol Metab 89:6239-43. 2004
    ..Women with a history of preeclampsia demonstrate altered expression of angiogenesis-related proteins and increased HOMA(IR) more than 1 yr postpartum. These factors may contribute to their risk of future CVD...
  92. ncbi request reprint Polymorphisms of interleukin (IL)-1alpha, IL-1beta, IL-6, IL-10, and IL-18 and the risk of ovarian cancer
    Abigail W Bushley
    Etiology Program, Cancer Research Center of Hawaii, University of Hawaii, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Gynecol Oncol 95:672-9. 2004
    ....
  93. pmc Consortium analysis of 7 candidate SNPs for ovarian cancer
    Susan J Ramus
    Translational Research Laboratory, University College London EGA Institute for Women s Health, London, United Kingdom
    Int J Cancer 123:380-8. 2008
    ..These null results for SNPs identified from relatively large initial studies shows the importance of replicating associations by a consortium approach...
  94. ncbi request reprint Lipid-lowering drug use and breast cancer in older women: a prospective study
    Jane A Cauley
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Womens Health (Larchmt) 12:749-56. 2003
    ..To test the hypothesis that use of lipid-lowering drugs reduces the risk of breast cancer in older women...
  95. ncbi request reprint Comparison of acute and subclinical pelvic inflammatory disease
    Harold C Wiesenfeld
    Department of Obstetrics, Gynecology, and Reproductive Sciences and Magee Womens Research Institute, University of Pittsburgh School of Medicine, PA 15213, USA
    Sex Transm Dis 32:400-5. 2005
    ..The objective of this study was to compare the demographic, clinical, and microbiologic findings in women with subclinical pelvic inflammatory disease (PID) and women with acute PID...
  96. ncbi request reprint Seroprevalence of antibodies to Chlamydia pneumoniae in women with preeclampsia
    R Phillip Heine
    Duke University Medical Center, Durham, North Carolina, USA
    Obstet Gynecol 101:221-6. 2003
    ..We studied whether, like atherosclerosis, preeclampsia is related to seroprevalence of immunoglobulin (Ig) G antibodies to Chlamydia pneumoniae...