L D Nelson
Affiliation: University of California
- Neurological changes and emotional functioning in adults with Down SyndromeL D Nelson
University of California, Irvine, Medical Center, Neurology Department, 101 City Drive, Route 81, Building 53, Room 225, Orange, California 92868, USA
J Intellect Disabil Res 45:450-6. 2001..These results, along with abnormalities in brain imaging and the presence of pathological reflexes, suggested that frontal lobe dysfunction is likely to be an early manifestation of Alzheimer's Disease in Down Syndrome...
- Measuring personality and emotional functioning in multiple sclerosis: a cautionary noteLinda D Nelson
Neurology Department, University of California, Irvine, Medical Center, 101 The City Drive, Route 81, Building 53, Room 225, Orange, CA 92868, USA
Arch Clin Neuropsychol 18:419-29. 2003..This study extended prototypic research by using patients with MS, examining the stability of results over time (1 year), and introducing a more reliable method of deriving standard T-scores in the correction procedure...
- Learning and memory as a function of age in Down syndrome: a study using animal-based tasksLinda Nelson
Department of Neurology, University of California, Irvine, Medical Center, 101 City Drive, Route 81, Building 53, Room 225, Orange, CA 92868, USA
Prog Neuropsychopharmacol Biol Psychiatry 29:443-53. 2005..These changes may reflect prefrontal and medial temporal lobe dysfunction that is associated with the development of AD pathology in DS...
- Down syndrome and Alzheimer disease: response to donepezilIra T Lott
Department of Pediatrics, University of California, Irvine Medical Center, 101 The City Dr S, Bldg 2, Third Floor, Orange, CA 92868 4482, USA
Arch Neurol 59:1133-6. 2002..Individuals with Down syndrome who develop Alzheimer disease may show an improvement in cognitive functioning after treatment with acetylcholinesterase inhibitors...
- An experimental approach to detecting dementia in Down syndrome: a paradigm for Alzheimer's diseaseLinda D Nelson
Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, C8 749, Semel Institute, 760 Westwood Plaza, Los Angeles, CA 90095 1759, USA
Brain Cogn 64:92-103. 2007..Results demonstrated high validity and reliability of select tests. The implication of early symptom detection in a population at-risk for AD-type dementia was discussed in terms of potential brain regions of interest...
- Personality testing and epilepsy: comparison of two MMPI-2 correction proceduresLinda D Nelson
Department of Neurology, University of California Irvine, Irvine, CA, USA
Epilepsy Behav 5:911-8. 2004..These results suggest cautious interpretation of standard MMPI-2 scores in patients with epilepsy...