H H Nelson

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. ncbi Key epigenetic changes associated with lung cancer development: results from dense methylation array profiling
    Heather H Nelson
    Masonic Cancer Center, Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA
    Epigenetics 7:559-66. 2012
  2. ncbi Similar DNA methylation levels in specific imprinting control regions in children conceived with and without assisted reproductive technology: a cross-sectional study
    Susan E Puumala
    Center for Health Outcomes and Prevention Research, Sanford Research, Sioux Falls, SD, USA
    BMC Pediatr 12:33. 2012
  3. ncbi Model-based clustering of DNA methylation array data: a recursive-partitioning algorithm for high-dimensional data arising as a mixture of beta distributions
    E Andres Houseman
    Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, 02115, USA
    BMC Bioinformatics 9:365. 2008
  4. ncbi KRAS mutation, KRAS-LCS6 polymorphism, and non-small cell lung cancer
    H H Nelson
    Masonic Cancer Center, Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN 55455, USA
    Lung Cancer 69:51-3. 2010
  5. ncbi The relationship between tumor MSLN methylation and serum mesothelin (SMRP) in mesothelioma
    Heather H Nelson
    Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, USA roduction
    Epigenetics 6:1029-34. 2011
  6. ncbi Global methylation in exposure biology and translational medical science
    Heather H Nelson
    Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA
    Environ Health Perspect 119:1528-33. 2011

Collaborators

Detail Information

Publications6

  1. ncbi Key epigenetic changes associated with lung cancer development: results from dense methylation array profiling
    Heather H Nelson
    Masonic Cancer Center, Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA
    Epigenetics 7:559-66. 2012
    ..Our data indicate that the identified genes consistently have altered methylation in lung tumors. Our identified genes should be included in translational studies that aim to develop screening for early disease detection...
  2. ncbi Similar DNA methylation levels in specific imprinting control regions in children conceived with and without assisted reproductive technology: a cross-sectional study
    Susan E Puumala
    Center for Health Outcomes and Prevention Research, Sanford Research, Sioux Falls, SD, USA
    BMC Pediatr 12:33. 2012
    ..Results from previous studies have been mixed, but some methylation differences have been observed...
  3. ncbi Model-based clustering of DNA methylation array data: a recursive-partitioning algorithm for high-dimensional data arising as a mixture of beta distributions
    E Andres Houseman
    Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, 02115, USA
    BMC Bioinformatics 9:365. 2008
    ..Model-based cluster analysis is often used to identify DNA methylation subgroups in data, but it is unclear how to cluster DNA methylation data from arrays in a scalable and reliable manner...
  4. ncbi KRAS mutation, KRAS-LCS6 polymorphism, and non-small cell lung cancer
    H H Nelson
    Masonic Cancer Center, Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN 55455, USA
    Lung Cancer 69:51-3. 2010
    ..Further, we find no association between the LCS6 polymorphism and lung cancer survival. These unexpected findings imply that this newly reported KRAS-LCS6 polymorphism will have limited clinical utility for NSCLC...
  5. ncbi The relationship between tumor MSLN methylation and serum mesothelin (SMRP) in mesothelioma
    Heather H Nelson
    Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, USA roduction
    Epigenetics 6:1029-34. 2011
    ..These results may lead to additional biomarker targets that will resolve the poor sensitivity of the SMRP assay and allow implementation of screening among exposed populations...
  6. ncbi Global methylation in exposure biology and translational medical science
    Heather H Nelson
    Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA
    Environ Health Perspect 119:1528-33. 2011
    ..There is an emerging literature that uses CpG methylation at repetitive sequences, including LINE-1 (long interspersed nuclear element-1) elements, to capture the epigenomic state...