A Negrusz

Summary

Affiliation: University of Illinois at Chicago
Country: USA

Publications

  1. ncbi request reprint Analytical developments in toxicological investigation of drug-facilitated sexual assault
    Adam Negrusz
    Department of Biopharmaceutical Sciences M C 865, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL 60612, USA
    Anal Bioanal Chem 376:1192-7. 2003
  2. ncbi request reprint Elimination of 7-aminoclonazepam in urine after a single dose of clonazepam
    Adam Negrusz
    Department of Biopharmaceutical Sciences M C 865, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL 60612, USA
    Anal Bioanal Chem 376:1198-204. 2003
  3. ncbi request reprint Deposition of 7-aminoclonazepam and clonazepam in hair following a single dose of Klonopin
    Adam Negrusz
    Department of Biopharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, 60612, USA
    J Anal Toxicol 26:471-8. 2002
  4. ncbi request reprint Detection of doxepin and its major metabolite desmethyldoxepin in hair following drug therapy
    A Negrusz
    Department of Pharmaceutics and Pharmacodynamics, College of Pharmacy, University of Illinois at Chicago, 60612, USA
    J Anal Toxicol 22:531-6. 1998
  5. ncbi request reprint Detection of ketamine and norketamine in urine of nonhuman primates after a single dose of ketamine using microplate enzyme-linked immunosorbent assay (ELISA) and NCI-GC-MS
    Adam Negrusz
    Department of Biopharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, Illinois 60612, USA
    J Anal Toxicol 29:163-8. 2005
  6. ncbi request reprint Deposition of 7-aminoflunitrazepam and flunitrazepam in hair after a single dose of Rohypnol
    A Negrusz
    Department of Pharmaceutics and Pharmacodynamics, College of Pharmacy, University of Illinois at Chicago, 60612, USA
    J Forensic Sci 46:1143-51. 2001
  7. ncbi request reprint The behavioral and cognitive effects of two benzodiazepines associated with drug-facilitated sexual assault
    Sheila M Dowd
    Department of Psychiatry, College of Medicine, University of Illinois at Chicago, USA
    J Forensic Sci 47:1101-7. 2002
  8. ncbi request reprint Development of an analytical approach to the specimens collected from victims of sexual assault
    Matthew Juhascik
    Department of Biopharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, Illinois 60612, USA
    J Anal Toxicol 28:400-6. 2004
  9. ncbi request reprint An estimate of the proportion of drug-facilitation of sexual assault in four U.S. localities
    Matthew P Juhascik
    Forensic Science Group, Department of Biopharmaceutical Sciences, University of Illinois at Chicago, Chicago, IL 60612, USA
    J Forensic Sci 52:1396-400. 2007
  10. ncbi request reprint Detection and quantification of low levels of benzoylecgonine in equine urine
    Connie Luckie
    Animal Forensic Toxicology Laboratory, University of Illinois at Chicago, 2242 West Harrison Street, Chicago, IL, USA
    Forensic Sci Int 177:e21-4. 2008

Collaborators

  • Sheila M Dowd
  • Piotr Adamowicz
  • R Bhat
  • R E Gaensslen
  • Christine Moore
  • Linda Ledray
  • Marc Benoit
  • Connie Luckie
  • Matthew P Juhascik
  • Matthew Juhascik
  • Laura Hurt
  • Esau Cardenas
  • Carolyn Whitney
  • David Schwope
  • Salvador Flores
  • Lisa M Taddei
  • David Mayer
  • Joshua Peterson
  • Kelly Lingen
  • Lisa Taddei
  • Joseph A Lokanc
  • Dawn Folker-Calderon
  • Andre Sukta
  • Katherine Lingner
  • Brendan T Heffron
  • Donna Pilipiak
  • Diana Faugno
  • Barbara Haner
  • Alice Lindner
  • Pam Greene
  • Kimberly Tomlinson
  • Ngog Lan Le
  • S E Aks
  • I Tebbett
  • D O Hryhorczuk
  • T L Vander Hoek

Detail Information

Publications13

  1. ncbi request reprint Analytical developments in toxicological investigation of drug-facilitated sexual assault
    Adam Negrusz
    Department of Biopharmaceutical Sciences M C 865, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL 60612, USA
    Anal Bioanal Chem 376:1192-7. 2003
    ..We discuss the most recent analytical developments in the toxicological investigation of drug-facilitated rape designed to reveal drug presence and that may help successfully prosecute perpetrators...
  2. ncbi request reprint Elimination of 7-aminoclonazepam in urine after a single dose of clonazepam
    Adam Negrusz
    Department of Biopharmaceutical Sciences M C 865, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL 60612, USA
    Anal Bioanal Chem 376:1198-204. 2003
    ..The range of concentrations detected was from 73.0 pg x mL(-1) to 183.2 ng x mL(-1). CLO was not detected in any of the samples...
  3. ncbi request reprint Deposition of 7-aminoclonazepam and clonazepam in hair following a single dose of Klonopin
    Adam Negrusz
    Department of Biopharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, 60612, USA
    J Anal Toxicol 26:471-8. 2002
    ..7-3.0 pg/mg), and in two subjects it was detectable 21 days later (4.9 and 2.7 pg/mg and 1.2 and 23 pg/mg). In two volunteers 7-ACLO was detected only on day 28 (1.8 and 3.3 pg/mg). CLO was not detected in any of the samples...
  4. ncbi request reprint Detection of doxepin and its major metabolite desmethyldoxepin in hair following drug therapy
    A Negrusz
    Department of Pharmaceutics and Pharmacodynamics, College of Pharmacy, University of Illinois at Chicago, 60612, USA
    J Anal Toxicol 22:531-6. 1998
    ..Five months after doxepin therapy was terminated, the drug and its metabolite were still present in the patient's hair. The concentration of doxepin in hair was always significantly higher than the concentration of desmethyldoxepin...
  5. ncbi request reprint Detection of ketamine and norketamine in urine of nonhuman primates after a single dose of ketamine using microplate enzyme-linked immunosorbent assay (ELISA) and NCI-GC-MS
    Adam Negrusz
    Department of Biopharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, Illinois 60612, USA
    J Anal Toxicol 29:163-8. 2005
    ..We propose that NCI-GC-MS be employed to detect NKET as a target compound in urine in toxicological investigations of drug-facilitated sexual assault when KET use by the perpetrator is suspected...
  6. ncbi request reprint Deposition of 7-aminoflunitrazepam and flunitrazepam in hair after a single dose of Rohypnol
    A Negrusz
    Department of Pharmaceutics and Pharmacodynamics, College of Pharmacy, University of Illinois at Chicago, 60612, USA
    J Forensic Sci 46:1143-51. 2001
    ..Flunitrazepam was detected in some samples but all concentrations were below the quantitation limit (0.5-2.3 pg/mg)...
  7. ncbi request reprint The behavioral and cognitive effects of two benzodiazepines associated with drug-facilitated sexual assault
    Sheila M Dowd
    Department of Psychiatry, College of Medicine, University of Illinois at Chicago, USA
    J Forensic Sci 47:1101-7. 2002
    ..CLO affected memory and attention throughout the study (6 h), and psychomotor performance was decreased 2 h post ingestion. In both studies, subjects were disinhibited and did not perceive their own impairment...
  8. ncbi request reprint Development of an analytical approach to the specimens collected from victims of sexual assault
    Matthew Juhascik
    Department of Biopharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, Illinois 60612, USA
    J Anal Toxicol 28:400-6. 2004
    ..This method is recommended for any laboratory that commonly receives specimens collected from sexual assault victims and is interested in a more thorough analysis...
  9. ncbi request reprint An estimate of the proportion of drug-facilitation of sexual assault in four U.S. localities
    Matthew P Juhascik
    Forensic Science Group, Department of Biopharmaceutical Sciences, University of Illinois at Chicago, Chicago, IL 60612, USA
    J Forensic Sci 52:1396-400. 2007
    ..Overall, cases of 43% of 144 subjects, and 7% of 859 complainants, were characterized as DFSA. Subjects underreported their use of drugs. The role of toxicological results and history in characterizing DFSA cases is discussed...
  10. ncbi request reprint Detection and quantification of low levels of benzoylecgonine in equine urine
    Connie Luckie
    Animal Forensic Toxicology Laboratory, University of Illinois at Chicago, 2242 West Harrison Street, Chicago, IL, USA
    Forensic Sci Int 177:e21-4. 2008
    ..To date, the laboratory has not reported concentrations of BE that exceed the established threshold concentration of 150 ng/mL...
  11. ncbi request reprint Cocaine liberation from body packets in an in vitro model
    S E Aks
    Department of Occupational Medicine, Cook County Hospital, Chicago, Illinois 60612
    Ann Emerg Med 21:1321-5. 1992
    ..To quantitatively assess cocaine liberation from various body packet materials...
  12. ncbi request reprint Cocaine permeability and metabolism in colonic T-84 epithelial cell line
    R Bhat
    Department of Pediatrics, University of Illinois at Chicago, 60612, USA
    Life Sci 70:549-56. 2001
    ..These studies imply that cocaine in swallowed amniotic fluid can be absorbed by the fetal gastrointestinal tract...
  13. ncbi request reprint Pyrilamine and O-desmethylpyrilamine detection in equine serum and urine
    Marc Benoit
    Animal Forensic Toxicology Laboratory, University of Illinois at Chicago, 2242 West Harrison Street, Chicago, Ilinois 60612, USA
    J Anal Toxicol 32:667-72. 2008
    ....