Research Topics
| A NegruszSummaryAffiliation: University of Illinois at Chicago Country: USA Publications
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Detail Information
Publications
Analytical developments in toxicological investigation of drug-facilitated sexual assaultAdam Negrusz
Department of Biopharmaceutical Sciences M C 865, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL 60612, USA
Anal Bioanal Chem 376:1192-7. 2003..We discuss the most recent analytical developments in the toxicological investigation of drug-facilitated rape designed to reveal drug presence and that may help successfully prosecute perpetrators...- Elimination of 7-aminoclonazepam in urine after a single dose of clonazepamAdam Negrusz
Department of Biopharmaceutical Sciences M C 865, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL 60612, USA
Anal Bioanal Chem 376:1198-204. 2003..The range of concentrations detected was from 73.0 pg x mL(-1) to 183.2 ng x mL(-1). CLO was not detected in any of the samples... - Deposition of 7-aminoclonazepam and clonazepam in hair following a single dose of KlonopinAdam Negrusz
Department of Biopharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, 60612, USA
J Anal Toxicol 26:471-8. 2002..7-3.0 pg/mg), and in two subjects it was detectable 21 days later (4.9 and 2.7 pg/mg and 1.2 and 23 pg/mg). In two volunteers 7-ACLO was detected only on day 28 (1.8 and 3.3 pg/mg). CLO was not detected in any of the samples... - Detection of doxepin and its major metabolite desmethyldoxepin in hair following drug therapyA Negrusz
Department of Pharmaceutics and Pharmacodynamics, College of Pharmacy, University of Illinois at Chicago, 60612, USA
J Anal Toxicol 22:531-6. 1998..Five months after doxepin therapy was terminated, the drug and its metabolite were still present in the patient's hair. The concentration of doxepin in hair was always significantly higher than the concentration of desmethyldoxepin... - Detection of ketamine and norketamine in urine of nonhuman primates after a single dose of ketamine using microplate enzyme-linked immunosorbent assay (ELISA) and NCI-GC-MSAdam Negrusz
Department of Biopharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, Illinois 60612, USA
J Anal Toxicol 29:163-8. 2005..We propose that NCI-GC-MS be employed to detect NKET as a target compound in urine in toxicological investigations of drug-facilitated sexual assault when KET use by the perpetrator is suspected... - Deposition of 7-aminoflunitrazepam and flunitrazepam in hair after a single dose of RohypnolA Negrusz
Department of Pharmaceutics and Pharmacodynamics, College of Pharmacy, University of Illinois at Chicago, 60612, USA
J Forensic Sci 46:1143-51. 2001..Flunitrazepam was detected in some samples but all concentrations were below the quantitation limit (0.5-2.3 pg/mg)... - The behavioral and cognitive effects of two benzodiazepines associated with drug-facilitated sexual assaultSheila M Dowd
Department of Psychiatry, College of Medicine, University of Illinois at Chicago, USA
J Forensic Sci 47:1101-7. 2002..CLO affected memory and attention throughout the study (6 h), and psychomotor performance was decreased 2 h post ingestion. In both studies, subjects were disinhibited and did not perceive their own impairment... - Development of an analytical approach to the specimens collected from victims of sexual assaultMatthew Juhascik
Department of Biopharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, Illinois 60612, USA
J Anal Toxicol 28:400-6. 2004..This method is recommended for any laboratory that commonly receives specimens collected from sexual assault victims and is interested in a more thorough analysis... - An estimate of the proportion of drug-facilitation of sexual assault in four U.S. localitiesMatthew P Juhascik
Forensic Science Group, Department of Biopharmaceutical Sciences, University of Illinois at Chicago, Chicago, IL 60612, USA
J Forensic Sci 52:1396-400. 2007..Overall, cases of 43% of 144 subjects, and 7% of 859 complainants, were characterized as DFSA. Subjects underreported their use of drugs. The role of toxicological results and history in characterizing DFSA cases is discussed... - Detection and quantification of low levels of benzoylecgonine in equine urineConnie Luckie
Animal Forensic Toxicology Laboratory, University of Illinois at Chicago, 2242 West Harrison Street, Chicago, IL, USA
Forensic Sci Int 177:e21-4. 2008..To date, the laboratory has not reported concentrations of BE that exceed the established threshold concentration of 150 ng/mL... - Cocaine liberation from body packets in an in vitro modelS E Aks
Department of Occupational Medicine, Cook County Hospital, Chicago, Illinois 60612
Ann Emerg Med 21:1321-5. 1992..To quantitatively assess cocaine liberation from various body packet materials... - Cocaine permeability and metabolism in colonic T-84 epithelial cell lineR Bhat
Department of Pediatrics, University of Illinois at Chicago, 60612, USA
Life Sci 70:549-56. 2001..These studies imply that cocaine in swallowed amniotic fluid can be absorbed by the fetal gastrointestinal tract... - Pyrilamine and O-desmethylpyrilamine detection in equine serum and urineMarc Benoit
Animal Forensic Toxicology Laboratory, University of Illinois at Chicago, 2242 West Harrison Street, Chicago, Ilinois 60612, USA
J Anal Toxicol 32:667-72. 2008....