Research Topics
| R D NebesSummaryAffiliation: University of Pittsburgh Country: USA Publications
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Detail Information
Publications
Cognitive and motor slowing in Alzheimer's disease and geriatric depressionR D Nebes
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, PA 15213, USA
J Int Neuropsychol Soc 4:426-34. 1998..Thus, this study suggests that AD produces a slowing in both cognitive and motor processes, whereas depression results solely in a motor retardation...
The nature and determinants of neuropsychological functioning in late-life depressionMeryl A Butters
Department of Psychiatry, University of Pittsburgh Medical Center, PA, USA
Arch Gen Psychiatry 61:587-95. 2004..Further studies of neuropsychological functioning in remitted LLD patients are needed to parse episode-related and persistent factors and to relate them to underlying neural dysfunction...
Instantiation of semantic categories in sentence comprehension by Alzheimer patientsR D Nebes
Department of Psychiatry, University of Pittsburgh School of Medicine, USA
J Int Neuropsychol Soc 5:685-91. 1999..Results showed that Alzheimer patients were highly accurate at instantiating even objects they could not name. This is consistent with a relative preservation of semantic knowledge about concrete objects in Alzheimer patients...
Relationship of deep white matter hyperintensities and apolipoprotein E genotype to depressive symptoms in older adults without clinical depressionR D Nebes
Western Psychiatric Institute and Clinic, Thomas Detre Hall, 3811 O Hara St, Pittsburgh, PA 15213, USA
Am J Psychiatry 158:878-84. 2001....
Dual-task performance in depressed geriatric patientsR D Nebes
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Psychiatry Res 102:139-51. 2001....
Longitudinal increase in the volume of white matter hyperintensities in late-onset depressionRobert D Nebes
Department of Psychiatry, WPIC, University of Pittsburgh School of Medicine, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Int J Geriatr Psychiatry 17:526-30. 2002..However, at present there is little evidence that a longitudinal increase in WMH burden within an individual is associated with the onset of a late-life depression...
Persistence of cognitive impairment in geriatric patients following antidepressant treatment: a randomized, double-blind clinical trial with nortriptyline and paroxetineRobert D Nebes
Intervention Research Center for the Study of Late Life Mood Disorders, Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
J Psychiatr Res 37:99-108. 2003..The present results suggest that cognitive dysfunction persists in older depressed patients even after their mood disorder has responded to antidepressant medications...
Serum anticholinergic activity, white matter hyperintensities, and cognitive performanceR D Nebes
Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
Neurology 65:1487-9. 2005....
The relation of White Matter Hyperintensities to implicit learning in healthy older adultsH J Aizenstein
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Int J Geriatr Psychiatry 17:664-9. 2002....
Complementary category learning systems identified using event-related functional MRIH J Aizenstein
University of Pittsburgh Medical School, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, USA
J Cogn Neurosci 12:977-87. 2000..Moreover, in both the implicit and explicit conditions a similar pattern of decreased activation was found in parietal regions. This commonality suggests that these dissociable systems also operate in parallel...
Hypothyroidism and cognition: preliminary evidence for a specific defect in memoryL A Burmeister
Department of Medicine, University of Pittsburgh School of Medicine, Pennsylvania, USA
Thyroid 11:1177-85. 2001....
Executive functioning, illness course, and relapse/recurrence in continuation and maintenance treatment of late-life depression: is there a relationship?Meryl A Butters
Intervention Research Center for Late Life Mood Disorders, Western Psychiatric Institute and Clinic, Department of Psychiatry, University of Pittsburgh Medical Center, USA
Am J Geriatr Psychiatry 12:387-94. 2004..The authors tested the hypothesis that impaired executive functioning leads to high rates of relapse and recurrence in late-life depression...
The relation of white matter hyperintensities to cognitive performance in the normal old: education mattersRobert D Nebes
University of Pittsburgh Medical Center, Pennsylvania, USA
Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 13:326-40. 2006..This is consistent with recent concepts of cognitive reserve, but does raise a question as to the underlying source of the cognitive decrement found in the sort of well-educated elders typically used in cognitive-aging studies...
Serum anticholinergic activity and motor performance in elderly personsRobert D Nebes
Department of Psychiatry, University of Pittsburgh Medical Center, Pennsylvania, USA
J Gerontol A Biol Sci Med Sci 62:83-5. 2007..Medications prescribed to elderly persons often have an anticholinergic effect, as do many commonly used over-the-counter drugs. Anticholinergic medications are known to produce psychomotor slowing, especially in older persons...
Prefrontal and striatal activation in elderly subjects during concurrent implicit and explicit sequence learningHoward J Aizenstein
Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Department of Psychiatry, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Neurobiol Aging 27:741-51. 2006..Moreover, these changes are observed during an implicit task, and thus do not seem to be mediated by awareness...
