Yuri N Naumov

Summary

Affiliation: University of Massachusetts Medical School
Country: USA

Publications

  1. pmc Quantitative measurement of pathogen-specific human memory T cell repertoire diversity using a CDR3 beta-specific microarray
    Xujing Wang
    The Max McGee National Research Center for Juvenile Diabetes, Department of Pediatrics, The Medical College of Wisconsin and The Children s Hospital Research Institute of Children s Hospital of Wisconsin, Milwaukee, WI 53226, USA
    BMC Genomics 8:329. 2007
  2. pmc Multiple glycines in TCR alpha-chains determine clonally diverse nature of human T cell memory to influenza A virus
    Yuri N Naumov
    Department of Pathology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Immunol 181:7407-19. 2008
  3. doi request reprint Selective T cell expansion during aging of CD8 memory repertoires to influenza revealed by modeling
    Yuri N Naumov
    Department of Pathology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Immunol 186:6617-24. 2011
  4. ncbi request reprint Complex T cell memory repertoires participate in recall responses at extremes of antigenic load
    Yuri N Naumov
    Department of Pathology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Immunol 177:2006-14. 2006
  5. pmc CD8 T cell cross-reactivity networks mediate heterologous immunity in human EBV and murine vaccinia virus infections
    Markus Cornberg
    Department of Pathology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Immunol 184:2825-38. 2010
  6. pmc Broad cross-reactive TCR repertoires recognizing dissimilar Epstein-Barr and influenza A virus epitopes
    Shalyn C Clute
    Department of Pathology and Program in Immunology and Virology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Immunol 185:6753-64. 2010
  7. ncbi request reprint A fractal clonotype distribution in the CD8+ memory T cell repertoire could optimize potential for immune responses
    Yuri N Naumov
    Department of Pathology, University of Massachusetts Medical School, Worchester, MA 01655, USA
    J Immunol 170:3994-4001. 2003
  8. pmc Cross-reactive influenza virus-specific CD8+ T cells contribute to lymphoproliferation in Epstein-Barr virus-associated infectious mononucleosis
    Shalyn C Clute
    Department of Pathology, Program in Immunology and Virology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    J Clin Invest 115:3602-12. 2005
  9. ncbi request reprint Memory of mice and men: CD8+ T-cell cross-reactivity and heterologous immunity
    Liisa K Selin
    Department of Pathology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Immunol Rev 211:164-81. 2006
  10. pmc CD1d-restricted T cells regulate dendritic cell function and antitumor immunity in a granulocyte-macrophage colony-stimulating factor-dependent fashion
    Silke Gillessen
    Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 100:8874-9. 2003

Collaborators

Detail Information

Publications10

  1. pmc Quantitative measurement of pathogen-specific human memory T cell repertoire diversity using a CDR3 beta-specific microarray
    Xujing Wang
    The Max McGee National Research Center for Juvenile Diabetes, Department of Pediatrics, The Medical College of Wisconsin and The Children s Hospital Research Institute of Children s Hospital of Wisconsin, Milwaukee, WI 53226, USA
    BMC Genomics 8:329. 2007
    ..We have used the memory T cell repertoire to an influenza-derived peptide as a test case for developing such a method...
  2. pmc Multiple glycines in TCR alpha-chains determine clonally diverse nature of human T cell memory to influenza A virus
    Yuri N Naumov
    Department of Pathology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Immunol 181:7407-19. 2008
    ....
  3. doi request reprint Selective T cell expansion during aging of CD8 memory repertoires to influenza revealed by modeling
    Yuri N Naumov
    Department of Pathology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Immunol 186:6617-24. 2011
    ..We propose that responses to periodic virus exposure may drive such expansion, ensuring that the remaining clonotypes are optimized for continued protection...
  4. ncbi request reprint Complex T cell memory repertoires participate in recall responses at extremes of antigenic load
    Yuri N Naumov
    Department of Pathology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Immunol 177:2006-14. 2006
    ....
  5. pmc CD8 T cell cross-reactivity networks mediate heterologous immunity in human EBV and murine vaccinia virus infections
    Markus Cornberg
    Department of Pathology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Immunol 184:2825-38. 2010
    ..Defining such cross-reactive networks between commonly encountered human pathogens may facilitate the design of vaccines...
  6. pmc Broad cross-reactive TCR repertoires recognizing dissimilar Epstein-Barr and influenza A virus epitopes
    Shalyn C Clute
    Department of Pathology and Program in Immunology and Virology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Immunol 185:6753-64. 2010
    ..We suggest that dissimilar cross-reactive epitopes might generate a broad, rather than a narrow, T cell repertoire if there is a lack of dominant high-affinity clones; this hypothesis is supported by computer simulation...
  7. ncbi request reprint A fractal clonotype distribution in the CD8+ memory T cell repertoire could optimize potential for immune responses
    Yuri N Naumov
    Department of Pathology, University of Massachusetts Medical School, Worchester, MA 01655, USA
    J Immunol 170:3994-4001. 2003
    ..Self similarity, power laws, and recursive mapping algorithms are associated with fractal systems. Thus, Ag-specific memory CD8 T cell repertoires can be considered as fractal, which could indicate optimized flexibility and robustness...
  8. pmc Cross-reactive influenza virus-specific CD8+ T cells contribute to lymphoproliferation in Epstein-Barr virus-associated infectious mononucleosis
    Shalyn C Clute
    Department of Pathology, Program in Immunology and Virology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    J Clin Invest 115:3602-12. 2005
    ..Our results support the concept that cross-reactive memory CD8+ T cells activated by EBV contribute to the characteristic lymphoproliferation of IM...
  9. ncbi request reprint Memory of mice and men: CD8+ T-cell cross-reactivity and heterologous immunity
    Liisa K Selin
    Department of Pathology, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Immunol Rev 211:164-81. 2006
    ....
  10. pmc CD1d-restricted T cells regulate dendritic cell function and antitumor immunity in a granulocyte-macrophage colony-stimulating factor-dependent fashion
    Silke Gillessen
    Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 100:8874-9. 2003
    ..DCs from immunized CD1d-deficient mice showed compromised maturation and function. Together, these results delineate a role for CD1d-restricted T cell-DC cross talk in the shaping of antitumor immunity...