Mehdi Nassiri

Summary

Affiliation: University of Miami
Country: USA

Publications

  1. pmc Preservation of skin DNA for oligonucleotide array CGH studies: a feasibility study
    Mehdi Nassiri
    Department of Pathology, University of Miami, Miller School of Medicine, Miami, FL 33136, USA
    Arch Dermatol Res 299:353-7. 2007
  2. ncbi request reprint Tissue detection of biomolecular predictors in breast cancer
    Mehdi Nassiri
    Department of Pathology, University of Miami, Sylvester Comprehensive Cancer Center, Miami, Florida 33101, USA
    Expert Rev Anticancer Ther 6:1225-32. 2006
  3. pmc Tissue targeting of anti-RNP autoimmunity: effects of T cells and myeloid dendritic cells in a murine model
    Eric L Greidinger
    Miami VA Medical Center, and University of Miami Miller School of Medicine, Miami, Florida, USA
    Arthritis Rheum 60:534-42. 2009
  4. pmc CD4+ T cells target epitopes residing within the RNA-binding domain of the U1-70-kDa small nuclear ribonucleoprotein autoantigen and have restricted TCR diversity in an HLA-DR4-transgenic murine model of mixed connective tissue disease
    Eric L Greidinger
    Division of Rheumatology and Immunology, Department of Medicine, Miller School of Medicine, University of Miami, Miami, FL 33101, USA
    J Immunol 180:8444-54. 2008
  5. doi request reprint Differential expression of smooth muscle regulatory proteins in the uterosacral ligaments of women with uterine prolapse
    Peter Takacs
    Department of Obstetrics and Gynecology, Miller School of Medicine, University of Miami, Miami, FL, USA
    Am J Obstet Gynecol 202:620.e1-5. 2010
  6. ncbi request reprint Methodology for preservation of high molecular-weight RNA in paraffin-embedded tissue: application for laser-capture microdissection
    Vladimir Vincek
    Department Pathology, University of Miami School of Medicine, Jackson Memorial Hospital, Holtz Center, Miami, Florida 33136, USA
    Diagn Mol Pathol 14:127-33. 2005
  7. doi request reprint Gene expression profiling reveals alteration of caspase 6 and 14 transcripts in normal skin of keloid-prone patients
    Mehdi Nassiri
    Department of Pathology, Laboratory Medicine, Indiana University School of Medicine, Clarian Pathology Laboratory 350 W 11th Street CPL 5044, Indianapolis, IN 46202, USA
    Arch Dermatol Res 301:183-8. 2009
  8. doi request reprint Fibulin-5 expression is decreased in women with anterior vaginal wall prolapse
    Peter Takacs
    Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology D 50, Miller School of Medicine, University of Miami Jackson Memorial Hospital, P O Box 016960, Miami, FL 33010, USA
    Int Urogynecol J Pelvic Floor Dysfunct 20:207-11. 2009
  9. doi request reprint Vaginal smooth muscle cell apoptosis is increased in women with pelvic organ prolapse
    Peter Takacs
    Department of Obstetrics and Gynecology D 50, University of Miami, Miller School of Medicine, Jackson Memorial Hospital, P O Box 016960, Miami, FL, 33010, USA
    Int Urogynecol J Pelvic Floor Dysfunct 19:1559-64. 2008
  10. doi request reprint Differential expression of fibulins in the uterosacral ligaments of women with uterine prolapse
    Peter Takacs
    Department of Obstetrics and Gynecology, Jackson Memorial Hospital, University of Miami, Miami, FL 33010, USA
    Arch Gynecol Obstet 282:389-94. 2010

Detail Information

Publications26

  1. pmc Preservation of skin DNA for oligonucleotide array CGH studies: a feasibility study
    Mehdi Nassiri
    Department of Pathology, University of Miami, Miller School of Medicine, Miami, FL 33136, USA
    Arch Dermatol Res 299:353-7. 2007
    ..On the other hand, the molecular fixative preserves tissue DNA similar to its fresh state with no discernable analytical differences...
  2. ncbi request reprint Tissue detection of biomolecular predictors in breast cancer
    Mehdi Nassiri
    Department of Pathology, University of Miami, Sylvester Comprehensive Cancer Center, Miami, Florida 33101, USA
    Expert Rev Anticancer Ther 6:1225-32. 2006
    ..To this end, novel tissue handling platforms are introduced that are not only suitable for histological diagnosis, but allow the detection of tumor proteome and expression profiles on the same biopsy sample...
  3. pmc Tissue targeting of anti-RNP autoimmunity: effects of T cells and myeloid dendritic cells in a murine model
    Eric L Greidinger
    Miami VA Medical Center, and University of Miami Miller School of Medicine, Miami, Florida, USA
    Arthritis Rheum 60:534-42. 2009
    ..To explore the role of immune cells in anti-RNP autoimmunity in a murine model of pneumonitis or glomerulonephritis, using adoptive transfer techniques...
  4. pmc CD4+ T cells target epitopes residing within the RNA-binding domain of the U1-70-kDa small nuclear ribonucleoprotein autoantigen and have restricted TCR diversity in an HLA-DR4-transgenic murine model of mixed connective tissue disease
    Eric L Greidinger
    Division of Rheumatology and Immunology, Department of Medicine, Miller School of Medicine, University of Miami, Miami, FL 33101, USA
    J Immunol 180:8444-54. 2008
    ....
  5. doi request reprint Differential expression of smooth muscle regulatory proteins in the uterosacral ligaments of women with uterine prolapse
    Peter Takacs
    Department of Obstetrics and Gynecology, Miller School of Medicine, University of Miami, Miami, FL, USA
    Am J Obstet Gynecol 202:620.e1-5. 2010
    ..To compare smooth muscle regulatory protein expression in the uterosacral ligament (USL) of women with and without uterine prolapse...
  6. ncbi request reprint Methodology for preservation of high molecular-weight RNA in paraffin-embedded tissue: application for laser-capture microdissection
    Vladimir Vincek
    Department Pathology, University of Miami School of Medicine, Jackson Memorial Hospital, Holtz Center, Miami, Florida 33136, USA
    Diagn Mol Pathol 14:127-33. 2005
    ..This methodology opens the door for a wide range of gene expression analyses using paraffin-embedded tissue...
  7. doi request reprint Gene expression profiling reveals alteration of caspase 6 and 14 transcripts in normal skin of keloid-prone patients
    Mehdi Nassiri
    Department of Pathology, Laboratory Medicine, Indiana University School of Medicine, Clarian Pathology Laboratory 350 W 11th Street CPL 5044, Indianapolis, IN 46202, USA
    Arch Dermatol Res 301:183-8. 2009
    ..Our results suggest that normal skin of keloid-prone individuals constitutively expresses a distinct gene profile which might contribute to their susceptibility to develop keloids...
  8. doi request reprint Fibulin-5 expression is decreased in women with anterior vaginal wall prolapse
    Peter Takacs
    Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology D 50, Miller School of Medicine, University of Miami Jackson Memorial Hospital, P O Box 016960, Miami, FL 33010, USA
    Int Urogynecol J Pelvic Floor Dysfunct 20:207-11. 2009
    ..3 (2-3), P = 0.04]. Fibulin-5 expression is decreased in vaginal biopsies from women with prolapse. Changes in fibulin expression may play a role in the development of pelvic organ prolapse...
  9. doi request reprint Vaginal smooth muscle cell apoptosis is increased in women with pelvic organ prolapse
    Peter Takacs
    Department of Obstetrics and Gynecology D 50, University of Miami, Miller School of Medicine, Jackson Memorial Hospital, P O Box 016960, Miami, FL, 33010, USA
    Int Urogynecol J Pelvic Floor Dysfunct 19:1559-64. 2008
    ..04 +/- 0.01 vs. 0.02 +/- 0.03, P = 0.041). The fraction of smooth muscle in the vagina is significantly decreased and the rate of apoptosis is higher in women with anterior vaginal wall prolapse compared to women without prolapse...
  10. doi request reprint Differential expression of fibulins in the uterosacral ligaments of women with uterine prolapse
    Peter Takacs
    Department of Obstetrics and Gynecology, Jackson Memorial Hospital, University of Miami, Miami, FL 33010, USA
    Arch Gynecol Obstet 282:389-94. 2010
    ..To compare fibulin-3 (FIB-3) and fibulin-5 (FIB-5) expressions in uterosacral ligaments (USL) of women with and without uterine prolapse...
  11. ncbi request reprint A tissue fixative that protects macromolecules (DNA, RNA, and protein) and histomorphology in clinical samples
    Vladimir Vincek
    Department of Pathology, Jackson Memorial Medical Center, University of Miami, Miami, Florida, USA
    Lab Invest 83:1427-35. 2003
    ..We concluded that it is now possible to preserve histomorphology and intact macromolecules in the same archival paraffin-embedded tissue through the use of a novel fixative and a rapid processing system...
  12. ncbi request reprint High proliferative activity excludes dermatofibroma: report of the utility of MIB-1 in the differential diagnosis of selected fibrohistiocytic tumors
    Andrew J Hanly
    Department of Pathology, University of Miami Jackson Memorial Medical Center, Miami, FL, USA
    Arch Pathol Lab Med 130:831-4. 2006
    ....
  13. ncbi request reprint Experience with an automated microwave-assisted rapid tissue processing method: validation of histologic quality and impact on the timeliness of diagnostic surgical pathology
    Azorides R Morales
    Department of Pathology, University of Miami Jackson Memorial Medical Center, FL, USA
    Am J Clin Pathol 121:528-36. 2004
    ..Moreover, use of the RTP enhanced safety by eliminating formalin and xylene from the procedure...
  14. ncbi request reprint Differential tissue targeting of autoimmunity manifestations by autoantigen-associated Y RNAs
    Eric L Greidinger
    Veterans Affairs Medical Center, and the University of Miami Miller School of Medicine, Miami, Florida USA
    Arthritis Rheum 56:1589-97. 2007
    ..To assess the Y RNAs, a family of homologous RNAs that bind to the Ro autoantigen, for the ability to contribute to autoimmune disease by activating RNA-responsive Toll-like receptors (TLRs)...
  15. doi request reprint Uterosacral ligament smooth muscle cell apoptosis is increased in women with uterine prolapse
    Peter Takacs
    Department of Obstetrics and Gynecology D 50, Jackson Memorial Hospital, University of Miami, Miller School of Medicine, PO Box 016960, Miami, FL 33010, USA
    Reprod Sci 16:447-52. 2009
    ..The purpose of this study was to compare the smooth muscle content and apoptosis of the uterosacral ligament in women with and without uterine prolapse...
  16. doi request reprint A gene signature of nonhealing venous ulcers: potential diagnostic markers
    Carlos A Charles
    Department of Dermatology, University of Miami Miller School of Medicine, Miami, Florida 33136, USA
    J Am Acad Dermatol 59:758-71. 2008
    ..Venous leg ulcers are responsible for more than half of all lower extremity ulcerations. Significant interest has been focused on understanding the physiologic basis on which patients fail to heal with standard therapy...
  17. ncbi request reprint Expression of p63 mRNA isoforms in normal human tissue
    Vladimir Vincek
    Departments of Pathology, Microbiology and Immunology, and Dermatology, University of Miami Jackson Memorial Medical Center, 1611 NW 12th Avenue, Holtz Center, Room 2042, Miami, FL 33136, USA
    Anticancer Res 23:3945-8. 2003
    ....
  18. doi request reprint Immunohistochemically determined estrogen receptor phenotype remains stable in recurrent and metastatic breast cancer
    Carmen Gomez-Fernandez
    Department of Pathology, University of Miami Miller School of Medicine, Miami, FL 33136, USA
    Am J Clin Pathol 130:879-82. 2008
    ..The time to distant metastasis was significantly longer for ER+ tumors. The immunohistochemically determined ER phenotype of primary breast cancers remains stable in most recurrent and metastatic disease...
  19. ncbi request reprint Effect of plasma exchange on cytokines measured by multianalyte bead array in thrombotic thrombocytopenic purpura
    Sherry Shariatmadar
    Department of Pathology, University of Miami School of Medicine, Miami, Florida 33101, USA
    Am J Hematol 79:83-8. 2005
    ....
  20. doi request reprint Caldesmon expression is decreased in women with anterior vaginal wall prolapse: a pilot study
    Peter Takacs
    Department of Obstetrics and Gynecology D 50, University of Miami, Miller School of Medicine, Jackson Memorial Hospital, P O Box 016960, Miami, FL 33010, USA
    Int Urogynecol J Pelvic Floor Dysfunct 20:985-90. 2009
    ..The purpose of this study is to compare vaginal caldesmon expression in women with and without anterior vaginal wall prolapse...
  21. ncbi request reprint The Pathology of full-thickness cadaver skin transplant for large abdominal defects: a proposed grading system for skin allograft acute rejection
    Pablo A Bejarano
    Department of Pathology, University of Miami School of Medicine Jackson Memorial Hospital, Miami, FL 33136, USA
    Am J Surg Pathol 28:670-5. 2004
    ..36. Among the 9 nonrejection cases, 4 specimens from 3 patients had thrombosis of the vessels feeding the graft. A grading system serves to better assess skin allograft rejection...
  22. ncbi request reprint Low nuclear proliferative activity is associated with nonmetastatic islet cell tumors
    Merce Jorda
    Department of Pathology, University of Miami, Jackson Memorial Medical Center, Miami, FL 33136, USA
    Arch Pathol Lab Med 127:196-9. 2003
    ....
  23. pmc Simultaneous measurement of multiple Th1 and Th2 serum cytokines in psoriasis and correlation with disease severity
    Sharon E Jacob
    Department of Dermatology and Cutaneous Surgery, University of Miami Jackson Memorial Medical Center, Holtz Center, Room 2042, 1611 NW 12 Avenue, Miami, FL 33136, USA
    Mediators Inflamm 12:309-13. 2003
    ..Psoriatic plaques have been shown to contain increased levels of proinflammatory cytokines. Serum levels of interleukin (IL)-6, IL-7, IL-8, and interferon (IFN)-gamma have been reported elevated in psoriatic patients...
  24. ncbi request reprint A murine model of mixed connective tissue disease induced with U1 small nuclear RNP autoantigen
    Eric L Greidinger
    Division of Rheumatology and Immunology, University of Miami, Miami, Florida 33136, USA
    Arthritis Rheum 54:661-9. 2006
    ..To test whether immunizing mice with autoantigens closely linked to mixed connective tissue disease (MCTD) could induce an MCTD-like clinical syndrome distinguishable from systemic lupus erythematosus (SLE)...
  25. ncbi request reprint Preservation of tissue RNA in normal saline
    Vladimir Vincek
    Department of Pathology, University of Miami Jackson Memorial Medical Center, Miami, Florida 33136, USA
    Lab Invest 83:137-8. 2003