Research Topics
Species | Katherine L NarrSummaryAffiliation: University of California Country: USA Publications
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Publications
Regional cortical thinning in subjects with violent antisocial personality disorder or schizophreniaVeena M Narayan
Laboratory of Neuro Imaging, Ahmanson Lovelace Brain Mapping Center, Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA
Am J Psychiatry 164:1418-27. 2007....
Relationships between IQ and regional cortical gray matter thickness in healthy adultsKatherine L Narr
Laboratory of Neuro Imaging, Department of Neurology, Geffen School of Medicine at the University of California, Los Angeles UCLA, Los Angeles, CA 90095 7334, USA
Cereb Cortex 17:2163-71. 2007..Sex moderates regional relationships that may index dimorphisms in cognitive abilities, overall processing strategies, or differences in structural organization...
Mean diffusivity: a biomarker for CSF-related disease and genetic liability effects in schizophreniaKatherine L Narr
Laboratory of Neuro Imaging, Geffen School of Medicine, UCLA, Los Angeles, CA, USA
Psychiatry Res 171:20-32. 2009....
DTNBP1 is associated with imaging phenotypes in schizophreniaKatherine L Narr
Laboratory of Neuro Imaging and Ahmanson Lovelace Brain Mapping Center, Department of Neurology, Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
Hum Brain Mapp 30:3783-94. 2009..Although DTNBP1 relates to cortical thinning in schizophrenia, morphological changes in the disorder are influenced by additional genetic and/or environmental factors...
Widespread cortical thinning is a robust anatomical marker for attention-deficit/hyperactivity disorderKatherine L Narr
David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA
J Am Acad Child Adolesc Psychiatry 48:1014-22. 2009....
Asymmetries of cortical shape: Effects of handedness, sex and schizophreniaKatherine L Narr
Laboratory of Neuro Imaging, Department of Neurology, Division of Brain Mapping, UCLA School of Medicine, 710 Westwood Plaza, Los Angeles, CA 90095 1769, USA
Neuroimage 34:939-48. 2007....
Mapping corticocortical structural integrity in schizophrenia and effects of genetic liabilityOwen R Phillips
Laboratory of Neuro Imaging, Department of Neurology, Geffen School of Medicine at University of California at Los Angeles, Los Angeles, California 90095 7334, USA
Biol Psychiatry 70:680-9. 2011..However, the structural integrity of the superficial WM, comprising short-range association (U-fibers) and intracortical axons, has not been investigated in schizophrenia...
Lateralized lexical decision in schizophrenia: hemispheric specialization and interhemispheric lexicality primingKatherine L Narr
Department of Neurology, University of California, Los Angeles, Los Angeles, CA 90095 1769, USA
J Abnorm Psychol 112:623-32. 2003..Results suggest that schizophrenia is associated with impaired monitoring and with increased interhemispheric automatic information transfer rather than with changed hemispheric specialization for language or error monitoring...
Regional specificity of hippocampal volume reductions in first-episode schizophreniaKatherine L Narr
Laboratory of Neuro Imaging, Department of Neurology, Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1769, USA
Neuroimage 21:1563-75. 2004..Targeting regional hippocampal abnormalities may help dissociate schizophrenia patients from other groups exhibiting global hippocampal volume changes, and better focus systems-level pathophysiological hypotheses...
Mean diffusivity and fractional anisotropy as indicators of disease and genetic liability to schizophreniaKristi A Clark
Laboratory of Neuro Imaging, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA
J Psychiatr Res 45:980-8. 2011..However, differences in FA and MD in frontal and temporal white matter pathways may be additionally driven by state variables that involve processes associated with the disease...
Cortical thinning in cingulate and occipital cortices in first episode schizophreniaKatherine L Narr
Laboratory of Neuro Imaging, Geffen School of Medicine at University of California at Los Angeles, Los Angeles, California, USA
Biol Psychiatry 58:32-40. 2005....
Disease and genetic contributions toward local tissue volume disturbances in schizophrenia: a tensor-based morphometry studyYaling Yang
Laboratory of Neuro Imaging, Geffen School of Medicine at UCLA, Los Angeles, CA 90024, USA
Hum Brain Mapp 33:2081-91. 2012..Thus, brain deformation profiles revealed in this study may help to clarify the role of specific genetic or environmental risk factors toward altered brain morphology in schizophrenia...
A longitudinal study of the long-term consequences of drinking during pregnancy: heavy in utero alcohol exposure disrupts the normal processes of brain developmentCatherine Lebel
Department of Neurology, University of California at Los Angeles, Los Angeles, California 90095 1769, USA
J Neurosci 32:15243-51. 2012..These results are encouraging in that interventions aimed at altering "experience" over time may improve brain trajectories in individuals with heavy PAE and possibly other neurodevelopmental disorders...
Topographical relationships between arcuate fasciculus connectivity and cortical thicknessOwen R Phillips
Laboratory of Neuro Imaging, Geffen School of Medicine, University of California, Los Angeles, California 90095 7334, USA
Hum Brain Mapp 32:1788-801. 2011....
Abnormal gyral complexity in first-episode schizophreniaKatherine L Narr
Laboratory of Neuro-Imaging, Geffen School of Medicine at University of California-Los Angeles, Los Angeles, CA 90095-1769, USA
Biol Psychiatry 55:859-67. 2004....
Increases in regional subarachnoid CSF without apparent cortical gray matter deficits in schizophrenia: modulating effects of sex and ageKatherine L Narr
Laboratory of Neuro Imaging, Department of Neurology, Division of Brain Mapping, UCLA School of Medicine, 710 Westwood Plaza, Los Angeles, CA 90095-1769, USA
Am J Psychiatry 160:2169-80. 2003..Cortical gray matter reductions show aging effects but are below the threshold of significance in schizophrenia...
The contributions of disease and genetic factors towards regional cortical thinning in schizophrenia: the UCLA family studyYaling Yang
Laboratory of Neuro Imaging, Geffen School of Medicine at UCLA, Los Angeles, CA 90024, United States
Schizophr Res 123:116-25. 2010..However, it remains unclear whether regional variations in cortical thickness may be attributable to disease-related or genetic-liability factors...
Comparing gray matter loss profiles between dementia with Lewy bodies and Alzheimer's disease using cortical pattern matching: diagnosis and gender effectsMartina Ballmaier
Laboratory of Neuroimaging, Department of Neurology, David Geffen UCLA School of Medicine, Los Angeles, CA 90095-1769, USA
Neuroimage 23:325-35. 2004..Further investigation of the influence of gender might provide a more comprehensive understanding of the pathophysiological differences underlying the two forms of dementia...
Reduced white matter integrity in attention-deficit hyperactivity disorderLiberty S Hamilton
Laboratory of Neuro Imaging, UCLA Neuropsychiatric Institute and Hospital in Los Angeles, Geffen School of Medicine at UCLA, Los Angeles, California, USA
Neuroreport 19:1705-8. 2008..Results support that disruptions in motor and attentional networks may contribute toward ADHD pathophysiology. Future research may clarify how ADHD subtype and psychiatric comorbidities affect diffusion measures...
Callosal thickness reductions relate to facial dysmorphology in fetal alcohol spectrum disordersYaling Yang
Laboratory of Neuro Imaging, Department of Neurology, University of California, Los Angeles, USA
Alcohol Clin Exp Res 36:798-806. 2012..Furthermore, associations between facial dysmorphology and callosal structure remain undetermined...
Decreased callosal thickness in attention-deficit/hyperactivity disorderEileen Luders
Laboratory of Neuro Imaging, Department of Neurology, University of California at Los Angeles School of Medicine, Los Angeles, California 90095 7334, USA
Biol Psychiatry 65:84-8. 2009..One of the most replicated alterations is a significantly smaller corpus callosum (CC), for which conflicting reports exist with respect to the affected callosal segments...
Alterations in functional activation in euthymic bipolar disorder and schizophrenia during a working memory taskLiberty S Hamilton
Laboratory of Neuro Imaging, Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90095 7334, USA
Hum Brain Mapp 30:3958-69. 2009..Both patient groups showed some regional task-related hypoactivation compared to controls across the brain. Within DLPFC specifically, patients with schizophrenia exhibited more severe WM-related dysfunction than bipolar subjects...
Genetic contributions to altered callosal morphology in schizophreniaKatherine L Narr
Laboratory of Neuro Imaging, Neuropsychiatric Institute, University of California at Los Angeles School of Medicine, Los Angeles, California 90095-1769, USA
J Neurosci 22:3720-9. 2002..An upward bowing of the callosum may thus provide an easily identifiable neuroanatomic marker to screen individuals possessing a biological vulnerability for schizophrenia...
A twin study of genetic contributions to hippocampal morphology in schizophreniaKatherine L Narr
Laboratory of Neuro-Imaging, Brain Mapping Center, Department of Neurology, UCLA Brain Mapping Center, UCLA School of Medicine, Los Angeles, California 90095, USA
Neurobiol Dis 11:83-95. 2002..Results suggest that hippocampal volume reduction may be a trait marker for identifying individuals possessing a genetic predisposition for schizophrenia...
Localizing gray matter deficits in late-onset depression using computational cortical pattern matching methodsMartina Ballmaier
Laboratory of Neuro Imaging, Department of Neurology, Rm. 4238, Reed Neurological Research Center, David Geffen UCLA School of Medicine, 710 Westwood Plaza, Los Angeles, CA 90095-1769, USA
Am J Psychiatry 161:2091-9. 2004....
Mapping cortical thickness and gray matter concentration in first episode schizophreniaKatherine L Narr
Laboratory of Neuro Imaging, Department of Neurology, Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1769, USA
Cereb Cortex 15:708-19. 2005..Cortical thickness and gray matter concentration mapping produce similar results, although the concentration metric may be influenced by diagnostic differences in extra-cortical cerebrospinal fluid and surface curvature/complexity...
Regional specificity of cerebrospinal fluid abnormalities in first episode schizophreniaKatherine L Narr
Laboratory of Neuroimaging, Division of Brain Mapping, UCLA School of Medicine, 710 Westwood Plaza, Los Angeles, CA 90095-1769, USA
Psychiatry Res 146:21-33. 2006..In contrast, sulcal and subarachnoid CSF increases may be manifest near or before the first episode but after brain development is complete, reflecting pronounced reductions in proximal brain tissue...
Abnormal cortical thickness alterations in fetal alcohol spectrum disorders and their relationships with facial dysmorphologyYaling Yang
Laboratory of NeuroImaging LONI, Department of Neurology, University of California, Los Angeles, CA 90095, USA
Cereb Cortex 22:1170-9. 2012..Furthermore, the significant associations between thickness and dysmorphic measures suggest that the severity of brain anomalies may be reflected by that of the face...
Positive correlations between corpus callosum thickness and intelligenceEileen Luders
Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine, Los Angeles, CA 90095 7334, and Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY, USA
Neuroimage 37:1457-64. 2007..Our findings emphasize the importance of incorporating posterior (callosal) regions into the theories and models proposed to explain the anatomical substrates of intelligence...
Three-dimensional mapping of hippocampal anatomy in adolescents with bipolar disorderCarrie E Bearden
Department of Psychiatry and Biobehavioral Sciences, UCLA, 300 Building Medical Plaza, Suite 2265, Los Angeles, CA 90095, USA
J Am Acad Child Adolesc Psychiatry 47:515-25. 2008..Using the same three-dimensional mapping methods, we sought to investigate whether a similar pattern exists in adolescents with bipolar disorder...
Fiber tractography reveals disruption of temporal lobe white matter tracts in schizophreniaOwen R Phillips
Laboratory of Neuro Imaging, Department of Neurology, Geffen School of Medicine at UCLA, USA
Schizophr Res 107:30-8. 2009..Disruptions of connectivity within these pathways may potentially contribute to the disturbances of memory, language, and social cognitive processing that characterize the disorder...
Morphological alterations in the prefrontal cortex and the amygdala in unsuccessful psychopathsYaling Yang
Laboratory of Neuroimaging, University of California Los Angeles, Los Angeles, CA 90095, USA
J Abnorm Psychol 119:546-54. 2010....
Mapping the relationship between cortical convolution and intelligence: effects of genderEileen Luders
Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine, Los Angeles, CA 90095 7334, USA
Cereb Cortex 18:2019-26. 2008..This might lead to the development of sexually dimorphic information processing strategies and affect the relationship between intelligence and cortical convolution...
Greater regional cortical gray matter thickness in obsessive-compulsive disorderVeena M Narayan
Laboratory of Neuro Imaging, Department of Neurology, Geffen School of Medicine at UCLA, Los Angeles, California, USA
Neuroreport 19:1551-5. 2008....
Asymmetries of cortical thickness: effects of handedness, sex, and schizophreniaLiberty S Hamilton
Laboratory of Neuroimaging, Geffen School of Medicine at UCLA, Los Angeles, California 90095 7334, USA
Neuroreport 18:1427-31. 2007..Thus, dextrality relates to cortical thickness asymmetries, although schizophrenia may differentially affect asymmetry patterns across handedness...
White matter integrity, language, and childhood onset schizophreniaKristi Clark
Laboratory of Neuro Imaging, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA
Schizophr Res 138:150-6. 2012..Childhood-onset schizophrenia (COS) is a particularly severe form of schizophrenia, with an onset during a key time period for both cerebral pruning and myelination...
Construction of a 3D probabilistic atlas of human cortical structuresDavid W Shattuck
Laboratory of Neuro Imaging, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, 635 Charles Young Drive South, NRB1, Suite 225, Los Angeles, CA 90095, USA
Neuroimage 39:1064-80. 2008....
A meta-algorithm for brain extraction in MRIDavid E Rex
Laboratory of Neuro Imaging, Department of Neurology, David Geffen School of Medicine at UCLA, 710 Westwood Plaza, Los Angeles, CA 90095-1769, USA
Neuroimage 23:625-37. 2004..BEMA outperformed the individual algorithms, as well as interrater results from a subset of the scans, when compared for the mean Dice coefficient, a rating of the similarity of output masks to the manually defined gold standards...
Localization of deformations within the amygdala in individuals with psychopathyYaling Yang
Laboratory of Neuro Imaging, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA
Arch Gen Psychiatry 66:986-94. 2009....
Bridging the hemispheres in meditation: thicker callosal regions and enhanced fractional anisotropy (FA) in long-term practitionersEileen Luders
Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine, Los Angeles, CA 90095 7334, USA
Neuroimage 61:181-7. 2012..Moreover, longitudinal studies are required to address whether the observed callosal effects are induced by meditation or constitute an innate prerequisite for the start or successful continuation of meditation...
Abnormal structural correlates of response perseveration in individuals with psychopathyYaling Yang
Laboratory of Neuroimaging, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA 90024, USA
J Neuropsychiatry Clin Neurosci 23:107-10. 2011..The findings provide preliminary evidence suggesting potential contributions of frontotemporal structural deficits in neurocognitive impairment with perseveration in individuals with psychopathy...
The link between callosal thickness and intelligence in healthy children and adolescentsEileen Luders
Department of Neurology, UCLA School of Medicine, Los Angeles, CA 90095 7334, USA
Neuroimage 54:1823-30. 2011..Sex effects on links between callosal thickness and intelligence during childhood and adolescence are present but appear rather weak in general...
Reduced hippocampal and parahippocampal volumes in murderers with schizophreniaYaling Yang
Laboratory of Neuroimaging, Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA
Psychiatry Res 182:9-13. 2010..Future studies examining subtle morphological changes in frontal and limbic structures in association with clinical and behavioral characteristics may help further clarify the neurobiological basis of violent behavior...
Gender differences in cortical complexityEileen Luders
Laboratory of Neuroimaging, Department of Neurology, Brain Mapping Division, UCLA School of Medicine, 710 Westwood Plaza, 4238 Reed, Los Angeles, California 90095, USA
Nat Neurosci 7:799-800. 2004..Increased complexity implies more cortical surface area, which may offset gender differences in brain volume and account for behavioral gender differences...
Diminished gray matter within the hypothalamus in autism disorder: a potential link to hormonal effects?Florian Kurth
Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine, University of California at Los Angeles, 760 Westwood Plaza 47 417, Los Angeles, CA 90024 1759, USA
Biol Psychiatry 70:278-82. 2011..These characteristics are found irrespective of age, IQ, and gender of affected subjects. However, brain changes due to age, IQ, and gender might pose potential confounds in autism neuroimaging analyses...
Diffeomorphic sulcal shape analysis on the cortexShantanu H Joshi
Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine, Los Angeles, CA 90095, USA
IEEE Trans Med Imaging 31:1195-212. 2012..We demonstrate experimental results for sulcal shape mapping, cortical surface registration, and sulcal classification for two different surface extraction protocols for separate subject populations...
Mapping brain size and cortical gray matter changes in elderly depressionMartina Ballmaier
Laboratory of Neuro Imaging, Department of Neurology, David Geffen UCLA School of Medicine, 710 Westwood Plaza, Los Angeles, CA 90095-1769, USA
Biol Psychiatry 55:382-9. 2004....
Increased volume of the amygdala and hippocampus in bipolar patients treated with lithiumLara C Foland
Laboratory of Neuroimaging, Department of Neurology, University of California, UCLA School of Medicine, Los Angeles, California, USA
Neuroreport 19:221-4. 2008..Our findings may help to explain previous inconsistencies in the bipolar literature...
Gender effects on callosal thickness in scaled and unscaled spaceEileen Luders
Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine, Los Angeles, California 90095-7334, USA
Neuroreport 17:1103-6. 2006..Alternatively, given their regional specificity, the observed differences in unscaled callosal thickness may contribute to gender-specific cognition and behavior...
Three-dimensional mapping of hippocampal and amygdalar structure in euthymic adults with bipolar disorder not treated with lithiumLara C Foland-Ross
Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine, Los Angeles, CA, USA
Psychiatry Res 211:195-201. 2013..Future studies, nevertheless, that further elucidate the impact of age, course of illness, and medication on amygdala structure in bipolar disorder are warranted...
Anterior cingulate activation relates to local cortical thicknessCatherine E Hegarty
Jane and Terry Semel Institute of Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, USA
Neuroreport 23:420-4. 2012..No significant thickness-activation correlations were found in the prefrontal cortex. Correlations between cortical thickness and activation may occur only in certain brain regions...
Enhanced brain connectivity in long-term meditation practitionersEileen Luders
Department of Neurology, UCLA School of Medicine, Los Angeles, CA 90095 7334, USA
Neuroimage 57:1308-16. 2011....
Online resource for validation of brain segmentation methodsDavid W Shattuck
Laboratory of Neuro Imaging, David Geffen School of Medicine, University of California, Los Angeles, 635 Charles Young Drive South, NRB1, Suite 225, Los Angeles, California 90095, USA
Neuroimage 45:431-9. 2009..NeuroImage 13 (5), 856-876 (May) under several different program settings. Our results show that with proper parameter selection, all 3 algorithms can achieve satisfactory skull-stripping on the test data...
Genetic and environmental influences on cortical thickness among 14-year-old twinsYaling Yang
Laboratory of Neuro Imaging, Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
Neuroreport 23:702-6. 2012....
ADHD comorbidity can matter when assessing cortical thickness abnormalities in patients with bipolar disorderCatherine E Hegarty
Jane and Terry Semel Institute of Neuroscience and Human Behavior, University of California at Los Angeles UCLA, Los Angeles, CA 90095, USA
Bipolar Disord 14:843-55. 2012..We used a 2 × 2 design to evaluate the joint effects of BP and ADHD on cortical thickness and uncover the importance of ADHD comorbidity in BP subjects...
Statistical shape analysis of the corpus callosum in SchizophreniaShantanu H Joshi
Laboratory of Neuro Imaging, University of California, Los Angeles, CA 90095 7334, USA
Neuroimage 64:547-59. 2013..Results showed significant age, sex, and schizophrenia effects on both global and local callosal shape structure...
Localisation of increased prefrontal white matter in pathological liarsYaling Yang
Department of Psychology, University of Southern California, Los Angeles, and David Geffen School of Medicine, CA 90089 1061, USA
Br J Psychiatry 190:174-5. 2007..This white matter increase may predispose some individuals to pathological lying...
Why sex matters: brain size independent differences in gray matter distributions between men and womenEileen Luders
Laboratory of Neuro Imaging, Department of Neurology, School of Medicine, University of California, Los Angeles, Los Angeles, California 90095 7334, USA
J Neurosci 29:14265-70. 2009..Altogether, our findings suggest that the observed increased regional GM volumes in female brains constitute sex-dependent redistributions of tissue volume, rather than individual adjustments attributable to brain size...
Regional gray matter variation in male-to-female transsexualismEileen Luders
Department of Neurology, UCLA School of Medicine, Los Angeles, CA 90095 7334, USA
Neuroimage 46:904-7. 2009..These findings provide new evidence that transsexualism is associated with distinct cerebral pattern, which supports the assumption that brain anatomy plays a role in gender identity...
A diffusion tensor imaging tractography algorithm based on Navier-Stokes fluid mechanicsNathan S Hageman
Laboratory of Neuroimaging, University of California Los Angeles UCLA School of Medicine, Los Angeles, CA 90095, USA
IEEE Trans Med Imaging 28:348-60. 2009..Our method produced paths that were consistent with both known anatomy and directionally encoded color images of the DTI dataset...
Frontal information flow and connectivity in psychopathyYaling Yang
Laboratory of Neuro Imaging, Department of Neurology, David Geffen School of Medicine, University of California, 1721 Speyer Lane, Redondo Beach, Los Angeles, CA 90278, USA
Br J Psychiatry 201:408-9. 2012..Frontal information flow and connectivity may have a significant role in the neuropathology of psychopathy...
The unique brain anatomy of meditation practitioners: alterations in cortical gyrificationEileen Luders
Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine Los Angeles, CA, USA
Front Hum Neurosci 6:34. 2012..Due to the cross-sectional nature of this study, further research is necessary to determine the relative contribution of nature and nurture to links between cortical gyrification and meditation...
Cortex mapping reveals regionally specific patterns of genetic and disease-specific gray-matter deficits in twins discordant for schizophreniaTyrone D Cannon
Department of Psychology, University of California, 1285 Franz Hall, Los Angeles, CA 90095, USA
Proc Natl Acad Sci U S A 99:3228-33. 2002....
Regional brain volume reductions relate to facial dysmorphology and neurocognitive function in fetal alcohol spectrum disordersFlorence F Roussotte
Developmental Cognitive Neuroimaging Laboratory, Department of Neurology, University of California, Los Angeles 90095 7332, USA
Hum Brain Mapp 33:920-37. 2012....
Biomarkers to predict antidepressant responseAndrew F Leuchter
Semel Institute for Neuroscience and Human Behavior at UCLA, David Geffen School of Medicine at UCLA, Los Angeles, CA 90024, USA
Curr Psychiatry Rep 12:553-62. 2010..Once such biomarkers are validated, they could form the basis of new paradigms for antidepressant treatment selection...
Mapping callosal morphology in early- and late-onset elderly depression: an index of distinct changes in cortical connectivityMartina Ballmaier
Department of Psychiatry and Psychotherapy, Charite University Medicine, Campus Mitte, Berlin, Germany
Neuropsychopharmacology 33:1528-36. 2008..Patients with a late onset of depression may be at higher risk of illness progression and eventually dementia conversion than early-onset depression, with potentially important implications for research and therapy...
Hippocampal morphology and distinguishing late-onset from early-onset elderly depressionMartina Ballmaier
Department of Psychiatry and Psychotherapy, Charite University Medicine, Campus Mitte, Berlin
Am J Psychiatry 165:229-37. 2008..This study used three-dimensional mapping techniques to identify regional hippocampal abnormalities in early- and late-onset depression. Neuropsychological correlates of hippocampal morphology were also investigated...
CSF sub-compartments in relation to plasma osmolality in healthy controls and in patients with first episode schizophreniaHandan Gunduz-Bruce
Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
Psychiatry Res 155:57-66. 2007..These results suggest that plasma osmolality is related to ventricle size in healthy volunteers and that this physiological link is impaired in patients with first episode schizophrenia...
Research Grants
- Mapping the MTL Memory System in SchizophreniaKATHERINE NARR; Fiscal Year: 2007....
