Katherine L Narr

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Regional cortical thinning in subjects with violent antisocial personality disorder or schizophrenia
    Veena M Narayan
    Laboratory of Neuro Imaging, Ahmanson Lovelace Brain Mapping Center, Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA
    Am J Psychiatry 164:1418-27. 2007
  2. pmc Adolescents with prenatal cocaine exposure show subtle alterations in striatal surface morphology and frontal cortical volumes
    Florence Roussotte
    Department of Neurology, University of California, Los Angeles, CA, USA
    J Neurodev Disord 4:22. 2012
  3. pmc Widespread cortical thinning is a robust anatomical marker for attention-deficit/hyperactivity disorder
    Katherine L Narr
    David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA
    J Am Acad Child Adolesc Psychiatry 48:1014-22. 2009
  4. pmc Asymmetries of cortical shape: Effects of handedness, sex and schizophrenia
    Katherine L Narr
    Laboratory of Neuro Imaging, Department of Neurology, Division of Brain Mapping, UCLA School of Medicine, 710 Westwood Plaza, Los Angeles, CA 90095 1769, USA
    Neuroimage 34:939-48. 2007
  5. ncbi request reprint Lateralized lexical decision in schizophrenia: hemispheric specialization and interhemispheric lexicality priming
    Katherine L Narr
    Department of Neurology, University of California, Los Angeles, Los Angeles, CA 90095 1769, USA
    J Abnorm Psychol 112:623-32. 2003
  6. ncbi request reprint Relationships between IQ and regional cortical gray matter thickness in healthy adults
    Katherine L Narr
    Laboratory of Neuro Imaging, Department of Neurology, Geffen School of Medicine at the University of California, Los Angeles UCLA, Los Angeles, CA 90095 7334, USA
    Cereb Cortex 17:2163-71. 2007
  7. pmc DTNBP1 is associated with imaging phenotypes in schizophrenia
    Katherine L Narr
    Laboratory of Neuro Imaging and Ahmanson Lovelace Brain Mapping Center, Department of Neurology, Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
    Hum Brain Mapp 30:3783-94. 2009
  8. pmc Mapping corticocortical structural integrity in schizophrenia and effects of genetic liability
    Owen R Phillips
    Laboratory of Neuro Imaging, Department of Neurology, Geffen School of Medicine at University of California at Los Angeles, Los Angeles, California 90095 7334, USA
    Biol Psychiatry 70:680-9. 2011
  9. pmc Mean diffusivity: a biomarker for CSF-related disease and genetic liability effects in schizophrenia
    Katherine L Narr
    Laboratory of Neuro Imaging, Geffen School of Medicine, UCLA, Los Angeles, CA, USA
    Psychiatry Res 171:20-32. 2009
  10. pmc Mean diffusivity and fractional anisotropy as indicators of disease and genetic liability to schizophrenia
    Kristi A Clark
    Laboratory of Neuro Imaging, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA
    J Psychiatr Res 45:980-8. 2011

Research Grants

  1. Mapping the MTL Memory System in Schizophrenia
    KATHERINE NARR; Fiscal Year: 2007

Detail Information

Publications72

  1. pmc Regional cortical thinning in subjects with violent antisocial personality disorder or schizophrenia
    Veena M Narayan
    Laboratory of Neuro Imaging, Ahmanson Lovelace Brain Mapping Center, Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA
    Am J Psychiatry 164:1418-27. 2007
    ....
  2. pmc Adolescents with prenatal cocaine exposure show subtle alterations in striatal surface morphology and frontal cortical volumes
    Florence Roussotte
    Department of Neurology, University of California, Los Angeles, CA, USA
    J Neurodev Disord 4:22. 2012
    ..abstract:..
  3. pmc Widespread cortical thinning is a robust anatomical marker for attention-deficit/hyperactivity disorder
    Katherine L Narr
    David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA
    J Am Acad Child Adolesc Psychiatry 48:1014-22. 2009
    ....
  4. pmc Asymmetries of cortical shape: Effects of handedness, sex and schizophrenia
    Katherine L Narr
    Laboratory of Neuro Imaging, Department of Neurology, Division of Brain Mapping, UCLA School of Medicine, 710 Westwood Plaza, Los Angeles, CA 90095 1769, USA
    Neuroimage 34:939-48. 2007
    ....
  5. ncbi request reprint Lateralized lexical decision in schizophrenia: hemispheric specialization and interhemispheric lexicality priming
    Katherine L Narr
    Department of Neurology, University of California, Los Angeles, Los Angeles, CA 90095 1769, USA
    J Abnorm Psychol 112:623-32. 2003
    ..Results suggest that schizophrenia is associated with impaired monitoring and with increased interhemispheric automatic information transfer rather than with changed hemispheric specialization for language or error monitoring...
  6. ncbi request reprint Relationships between IQ and regional cortical gray matter thickness in healthy adults
    Katherine L Narr
    Laboratory of Neuro Imaging, Department of Neurology, Geffen School of Medicine at the University of California, Los Angeles UCLA, Los Angeles, CA 90095 7334, USA
    Cereb Cortex 17:2163-71. 2007
    ..Sex moderates regional relationships that may index dimorphisms in cognitive abilities, overall processing strategies, or differences in structural organization...
  7. pmc DTNBP1 is associated with imaging phenotypes in schizophrenia
    Katherine L Narr
    Laboratory of Neuro Imaging and Ahmanson Lovelace Brain Mapping Center, Department of Neurology, Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
    Hum Brain Mapp 30:3783-94. 2009
    ..Although DTNBP1 relates to cortical thinning in schizophrenia, morphological changes in the disorder are influenced by additional genetic and/or environmental factors...
  8. pmc Mapping corticocortical structural integrity in schizophrenia and effects of genetic liability
    Owen R Phillips
    Laboratory of Neuro Imaging, Department of Neurology, Geffen School of Medicine at University of California at Los Angeles, Los Angeles, California 90095 7334, USA
    Biol Psychiatry 70:680-9. 2011
    ..However, the structural integrity of the superficial WM, comprising short-range association (U-fibers) and intracortical axons, has not been investigated in schizophrenia...
  9. pmc Mean diffusivity: a biomarker for CSF-related disease and genetic liability effects in schizophrenia
    Katherine L Narr
    Laboratory of Neuro Imaging, Geffen School of Medicine, UCLA, Los Angeles, CA, USA
    Psychiatry Res 171:20-32. 2009
    ....
  10. pmc Mean diffusivity and fractional anisotropy as indicators of disease and genetic liability to schizophrenia
    Kristi A Clark
    Laboratory of Neuro Imaging, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA
    J Psychiatr Res 45:980-8. 2011
    ..However, differences in FA and MD in frontal and temporal white matter pathways may be additionally driven by state variables that involve processes associated with the disease...
  11. ncbi request reprint Regional specificity of hippocampal volume reductions in first-episode schizophrenia
    Katherine L Narr
    Laboratory of Neuro Imaging, Department of Neurology, Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1769, USA
    Neuroimage 21:1563-75. 2004
    ..Targeting regional hippocampal abnormalities may help dissociate schizophrenia patients from other groups exhibiting global hippocampal volume changes, and better focus systems-level pathophysiological hypotheses...
  12. ncbi request reprint Cortical thinning in cingulate and occipital cortices in first episode schizophrenia
    Katherine L Narr
    Laboratory of Neuro Imaging, Geffen School of Medicine at University of California at Los Angeles, Los Angeles, California, USA
    Biol Psychiatry 58:32-40. 2005
    ....
  13. pmc Disease and genetic contributions toward local tissue volume disturbances in schizophrenia: a tensor-based morphometry study
    Yaling Yang
    Laboratory of Neuro Imaging, Geffen School of Medicine at UCLA, Los Angeles, CA 90024, USA
    Hum Brain Mapp 33:2081-91. 2012
    ..Thus, brain deformation profiles revealed in this study may help to clarify the role of specific genetic or environmental risk factors toward altered brain morphology in schizophrenia...
  14. pmc A longitudinal study of the long-term consequences of drinking during pregnancy: heavy in utero alcohol exposure disrupts the normal processes of brain development
    Catherine Lebel
    Department of Neurology, University of California at Los Angeles, Los Angeles, California 90095 1769, USA
    J Neurosci 32:15243-51. 2012
    ..These results are encouraging in that interventions aimed at altering "experience" over time may improve brain trajectories in individuals with heavy PAE and possibly other neurodevelopmental disorders...
  15. pmc Topographical relationships between arcuate fasciculus connectivity and cortical thickness
    Owen R Phillips
    Laboratory of Neuro Imaging, Geffen School of Medicine, University of California, Los Angeles, California 90095 7334, USA
    Hum Brain Mapp 32:1788-801. 2011
    ....
  16. ncbi request reprint Abnormal gyral complexity in first-episode schizophrenia
    Katherine L Narr
    Laboratory of Neuro Imaging, Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA 90095 1769, USA
    Biol Psychiatry 55:859-67. 2004
    ..Few studies, however, have investigated gyral complexity in schizophrenia...
  17. ncbi request reprint Genetic contributions to altered callosal morphology in schizophrenia
    Katherine L Narr
    Laboratory of Neuro Imaging, Neuropsychiatric Institute, University of California at Los Angeles School of Medicine, Los Angeles, California 90095 1769, USA
    J Neurosci 22:3720-9. 2002
    ..An upward bowing of the callosum may thus provide an easily identifiable neuroanatomic marker to screen individuals possessing a biological vulnerability for schizophrenia...
  18. ncbi request reprint Comparing gray matter loss profiles between dementia with Lewy bodies and Alzheimer's disease using cortical pattern matching: diagnosis and gender effects
    Martina Ballmaier
    Laboratory of Neuroimaging, Department of Neurology, David Geffen UCLA School of Medicine, Los Angeles, CA 90095 1769, USA
    Neuroimage 23:325-35. 2004
    ..Further investigation of the influence of gender might provide a more comprehensive understanding of the pathophysiological differences underlying the two forms of dementia...
  19. pmc The contributions of disease and genetic factors towards regional cortical thinning in schizophrenia: the UCLA family study
    Yaling Yang
    Laboratory of Neuro Imaging, Geffen School of Medicine at UCLA, Los Angeles, CA 90024, United States
    Schizophr Res 123:116-25. 2010
    ..However, it remains unclear whether regional variations in cortical thickness may be attributable to disease-related or genetic-liability factors...
  20. pmc Reduced white matter integrity in attention-deficit hyperactivity disorder
    Liberty S Hamilton
    Laboratory of Neuro Imaging, UCLA Neuropsychiatric Institute and Hospital in Los Angeles, Geffen School of Medicine at UCLA, Los Angeles, California, USA
    Neuroreport 19:1705-8. 2008
    ..Results support that disruptions in motor and attentional networks may contribute toward ADHD pathophysiology. Future research may clarify how ADHD subtype and psychiatric comorbidities affect diffusion measures...
  21. ncbi request reprint Increases in regional subarachnoid CSF without apparent cortical gray matter deficits in schizophrenia: modulating effects of sex and age
    Katherine L Narr
    Laboratory of Neuro Imaging, Department of Neurology, Division of Brain Mapping, UCLA School of Medicine, 710 Westwood Plaza, Los Angeles, CA 90095 1769, USA
    Am J Psychiatry 160:2169-80. 2003
    ....
  22. pmc Callosal thickness reductions relate to facial dysmorphology in fetal alcohol spectrum disorders
    Yaling Yang
    Laboratory of Neuro Imaging, Department of Neurology, University of California, Los Angeles, USA
    Alcohol Clin Exp Res 36:798-806. 2012
    ..Furthermore, associations between facial dysmorphology and callosal structure remain undetermined...
  23. pmc Decreased callosal thickness in attention-deficit/hyperactivity disorder
    Eileen Luders
    Laboratory of Neuro Imaging, Department of Neurology, University of California at Los Angeles School of Medicine, Los Angeles, California 90095 7334, USA
    Biol Psychiatry 65:84-8. 2009
    ..One of the most replicated alterations is a significantly smaller corpus callosum (CC), for which conflicting reports exist with respect to the affected callosal segments...
  24. pmc Superficial white matter: effects of age, sex, and hemisphere
    Owen R Phillips
    Laboratory of Neuro Imaging, Department of Neurology, Geffen School of Medicine at UCLA, Los Angeles, California 90095 7334, USA
    Brain Connect 3:146-59. 2013
    ..SWM fiber organization/coherence appears greater in the left hemisphere regions spanning language and other networks, while more localized sex effects could possibly reflect sex-specific advantages in information strategies...
  25. pmc Three-dimensional mapping of hippocampal and amygdalar structure in euthymic adults with bipolar disorder not treated with lithium
    Lara C Foland-Ross
    Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine, Los Angeles, CA, USA
    Psychiatry Res 211:195-201. 2013
    ..Future studies, nevertheless, that further elucidate the impact of age, course of illness, and medication on amygdala structure in bipolar disorder are warranted...
  26. ncbi request reprint Regional specificity of cerebrospinal fluid abnormalities in first episode schizophrenia
    Katherine L Narr
    Laboratory of Neuroimaging, Division of Brain Mapping, UCLA School of Medicine, 710 Westwood Plaza, Los Angeles, CA 90095 1769, USA
    Psychiatry Res 146:21-33. 2006
    ..In contrast, sulcal and subarachnoid CSF increases may be manifest near or before the first episode but after brain development is complete, reflecting pronounced reductions in proximal brain tissue...
  27. ncbi request reprint Localizing gray matter deficits in late-onset depression using computational cortical pattern matching methods
    Martina Ballmaier
    Laboratory of Neuro Imaging, Department of Neurology, Rm 4238, Reed Neurological Research Center, David Geffen UCLA School of Medicine, 710 Westwood Plaza, Los Angeles, CA 90095 1769, USA
    Am J Psychiatry 161:2091-9. 2004
    ..The authors used magnetic resonance imaging and an image analysis technique known as cortical pattern matching to map cortical gray matter deficits in elderly depressed patients with an illness onset after age 60 (late-onset depression)...
  28. pmc Alterations in functional activation in euthymic bipolar disorder and schizophrenia during a working memory task
    Liberty S Hamilton
    Laboratory of Neuro Imaging, Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90095 7334, USA
    Hum Brain Mapp 30:3958-69. 2009
    ..Both patient groups showed some regional task-related hypoactivation compared to controls across the brain. Within DLPFC specifically, patients with schizophrenia exhibited more severe WM-related dysfunction than bipolar subjects...
  29. ncbi request reprint Mapping cortical thickness and gray matter concentration in first episode schizophrenia
    Katherine L Narr
    Laboratory of Neuro Imaging, Department of Neurology, Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1769, USA
    Cereb Cortex 15:708-19. 2005
    ..Cortical thickness and gray matter concentration mapping produce similar results, although the concentration metric may be influenced by diagnostic differences in extra-cortical cerebrospinal fluid and surface curvature/complexity...
  30. ncbi request reprint A twin study of genetic contributions to hippocampal morphology in schizophrenia
    Katherine L Narr
    Laboratory of Neuro Imaging, Brain Mapping Center, Department of Neurology, UCLA Brain Mapping Center, UCLA School of Medicine, Los Angeles, California 90095, USA
    Neurobiol Dis 11:83-95. 2002
    ..Results suggest that hippocampal volume reduction may be a trait marker for identifying individuals possessing a genetic predisposition for schizophrenia...
  31. pmc Abnormal cortical thickness alterations in fetal alcohol spectrum disorders and their relationships with facial dysmorphology
    Yaling Yang
    Laboratory of NeuroImaging LONI, Department of Neurology, University of California, Los Angeles, CA 90095, USA
    Cereb Cortex 22:1170-9. 2012
    ..Furthermore, the significant associations between thickness and dysmorphic measures suggest that the severity of brain anomalies may be reflected by that of the face...
  32. pmc Fiber tractography reveals disruption of temporal lobe white matter tracts in schizophrenia
    Owen R Phillips
    Laboratory of Neuro Imaging, Department of Neurology, Geffen School of Medicine at UCLA, USA
    Schizophr Res 107:30-8. 2009
    ..Disruptions of connectivity within these pathways may potentially contribute to the disturbances of memory, language, and social cognitive processing that characterize the disorder...
  33. pmc Positive correlations between corpus callosum thickness and intelligence
    Eileen Luders
    Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine, Los Angeles, CA 90095 7334, and Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY, USA
    Neuroimage 37:1457-64. 2007
    ..Our findings emphasize the importance of incorporating posterior (callosal) regions into the theories and models proposed to explain the anatomical substrates of intelligence...
  34. pmc Three-dimensional mapping of hippocampal anatomy in adolescents with bipolar disorder
    Carrie E Bearden
    Department of Psychiatry and Biobehavioral Sciences, UCLA, 300 Building Medical Plaza, Suite 2265, Los Angeles, CA 90095, USA
    J Am Acad Child Adolesc Psychiatry 47:515-25. 2008
    ..Using the same three-dimensional mapping methods, we sought to investigate whether a similar pattern exists in adolescents with bipolar disorder...
  35. pmc Statistical shape analysis of the corpus callosum in Schizophrenia
    Shantanu H Joshi
    Laboratory of Neuro Imaging, University of California, Los Angeles, CA 90095 7334, USA
    Neuroimage 64:547-59. 2013
    ..Results showed significant age, sex, and schizophrenia effects on both global and local callosal shape structure...
  36. doi request reprint Frontal information flow and connectivity in psychopathy
    Yaling Yang
    Laboratory of Neuro Imaging, Department of Neurology, David Geffen School of Medicine, University of California, 1721 Speyer Lane, Redondo Beach, Los Angeles, CA 90278, USA
    Br J Psychiatry 201:408-9. 2012
    ..Frontal information flow and connectivity may have a significant role in the neuropathology of psychopathy...
  37. doi request reprint Morphological alterations in the prefrontal cortex and the amygdala in unsuccessful psychopaths
    Yaling Yang
    Laboratory of Neuroimaging, University of California Los Angeles, Los Angeles, CA 90095, USA
    J Abnorm Psychol 119:546-54. 2010
    ....
  38. pmc Asymmetries of cortical thickness: effects of handedness, sex, and schizophrenia
    Liberty S Hamilton
    Laboratory of Neuroimaging, Geffen School of Medicine at UCLA, Los Angeles, California 90095 7334, USA
    Neuroreport 18:1427-31. 2007
    ..Thus, dextrality relates to cortical thickness asymmetries, although schizophrenia may differentially affect asymmetry patterns across handedness...
  39. pmc Greater regional cortical gray matter thickness in obsessive-compulsive disorder
    Veena M Narayan
    Laboratory of Neuro Imaging, Department of Neurology, Geffen School of Medicine at UCLA, Los Angeles, California, USA
    Neuroreport 19:1551-5. 2008
    ....
  40. pmc Mapping the relationship between cortical convolution and intelligence: effects of gender
    Eileen Luders
    Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine, Los Angeles, CA 90095 7334, USA
    Cereb Cortex 18:2019-26. 2008
    ..This might lead to the development of sexually dimorphic information processing strategies and affect the relationship between intelligence and cortical convolution...
  41. ncbi request reprint Global and regional alterations of hippocampal anatomy in long-term meditation practitioners
    Eileen Luders
    Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine, Los Angeles, California
    Hum Brain Mapp 34:3369-75. 2013
    ..However, given the cross-sectional design, the lack of individual stress measures, and the limited resolution of brain data, the exact underlying neuronal mechanisms remain to be established...
  42. pmc ADHD comorbidity can matter when assessing cortical thickness abnormalities in patients with bipolar disorder
    Catherine E Hegarty
    Jane and Terry Semel Institute of Neuroscience and Human Behavior, University of California at Los Angeles UCLA, Los Angeles, CA 90095, USA
    Bipolar Disord 14:843-55. 2012
    ..We used a 2 × 2 design to evaluate the joint effects of BP and ADHD on cortical thickness and uncover the importance of ADHD comorbidity in BP subjects...
  43. pmc White matter integrity, language, and childhood onset schizophrenia
    Kristi Clark
    Laboratory of Neuro Imaging, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA
    Schizophr Res 138:150-6. 2012
    ..Childhood-onset schizophrenia (COS) is a particularly severe form of schizophrenia, with an onset during a key time period for both cerebral pruning and myelination...
  44. ncbi request reprint A meta-algorithm for brain extraction in MRI
    David E Rex
    Laboratory of Neuro Imaging, Department of Neurology, David Geffen School of Medicine at UCLA, 710 Westwood Plaza, Los Angeles, CA 90095 1769, USA
    Neuroimage 23:625-37. 2004
    ..BEMA outperformed the individual algorithms, as well as interrater results from a subset of the scans, when compared for the mean Dice coefficient, a rating of the similarity of output masks to the manually defined gold standards...
  45. pmc Localization of deformations within the amygdala in individuals with psychopathy
    Yaling Yang
    Laboratory of Neuro Imaging, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA
    Arch Gen Psychiatry 66:986-94. 2009
    ....
  46. pmc Construction of a 3D probabilistic atlas of human cortical structures
    David W Shattuck
    Laboratory of Neuro Imaging, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, 635 Charles Young Drive South, NRB1, Suite 225, Los Angeles, CA 90095, USA
    Neuroimage 39:1064-80. 2008
    ....
  47. doi request reprint Relationships between gray matter, body mass index, and waist circumference in healthy adults
    Florian Kurth
    Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, Los Angeles, California 90024 1759, USA
    Hum Brain Mapp 34:1737-46. 2013
    ..Our observations suggest that waist circumference is a more sensitive indicator than BMI, particularly in females, for potentially determining the adverse effects of obesity and overweight on the brain and associated risks to health...
  48. pmc Bridging the hemispheres in meditation: thicker callosal regions and enhanced fractional anisotropy (FA) in long-term practitioners
    Eileen Luders
    Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine, Los Angeles, CA 90095 7334, USA
    Neuroimage 61:181-7. 2012
    ..Moreover, longitudinal studies are required to address whether the observed callosal effects are induced by meditation or constitute an innate prerequisite for the start or successful continuation of meditation...
  49. pmc The link between callosal thickness and intelligence in healthy children and adolescents
    Eileen Luders
    Department of Neurology, UCLA School of Medicine, Los Angeles, CA 90095 7334, USA
    Neuroimage 54:1823-30. 2011
    ..Sex effects on links between callosal thickness and intelligence during childhood and adolescence are present but appear rather weak in general...
  50. ncbi request reprint Gender differences in cortical complexity
    Eileen Luders
    Laboratory of Neuroimaging, Department of Neurology, Brain Mapping Division, UCLA School of Medicine, 710 Westwood Plaza, 4238 Reed, Los Angeles, California 90095, USA
    Nat Neurosci 7:799-800. 2004
    ..Increased complexity implies more cortical surface area, which may offset gender differences in brain volume and account for behavioral gender differences...
  51. pmc Diminished gray matter within the hypothalamus in autism disorder: a potential link to hormonal effects?
    Florian Kurth
    Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine, University of California at Los Angeles, 760 Westwood Plaza 47 417, Los Angeles, CA 90024 1759, USA
    Biol Psychiatry 70:278-82. 2011
    ..These characteristics are found irrespective of age, IQ, and gender of affected subjects. However, brain changes due to age, IQ, and gender might pose potential confounds in autism neuroimaging analyses...
  52. pmc Abnormal structural correlates of response perseveration in individuals with psychopathy
    Yaling Yang
    Laboratory of Neuroimaging, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA 90024, USA
    J Neuropsychiatry Clin Neurosci 23:107-10. 2011
    ..The findings provide preliminary evidence suggesting potential contributions of frontotemporal structural deficits in neurocognitive impairment with perseveration in individuals with psychopathy...
  53. pmc Reduced hippocampal and parahippocampal volumes in murderers with schizophrenia
    Yaling Yang
    Laboratory of Neuroimaging, Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA
    Psychiatry Res 182:9-13. 2010
    ..Future studies examining subtle morphological changes in frontal and limbic structures in association with clinical and behavioral characteristics may help further clarify the neurobiological basis of violent behavior...
  54. ncbi request reprint Diffeomorphic sulcal shape analysis on the cortex
    Shantanu H Joshi
    Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine, Los Angeles, CA 90095, USA
    IEEE Trans Med Imaging 31:1195-212. 2012
    ..We demonstrate experimental results for sulcal shape mapping, cortical surface registration, and sulcal classification for two different surface extraction protocols for separate subject populations...
  55. pmc Increased volume of the amygdala and hippocampus in bipolar patients treated with lithium
    Lara C Foland
    Laboratory of Neuroimaging, Department of Neurology, University of California, UCLA School of Medicine, Los Angeles, California, USA
    Neuroreport 19:221-4. 2008
    ..Our findings may help to explain previous inconsistencies in the bipolar literature...
  56. ncbi request reprint Mapping brain size and cortical gray matter changes in elderly depression
    Martina Ballmaier
    Laboratory of Neuro Imaging, Department of Neurology, David Geffen UCLA School of Medicine, 710 Westwood Plaza, Los Angeles, CA 90095 1769, USA
    Biol Psychiatry 55:382-9. 2004
    ..Here, we conducted detailed spatial analyses of brain size and gray matter within the cortical mantle in elderly patients with major depression...
  57. ncbi request reprint Gender effects on callosal thickness in scaled and unscaled space
    Eileen Luders
    Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine, Los Angeles, California 90095 7334, USA
    Neuroreport 17:1103-6. 2006
    ..Alternatively, given their regional specificity, the observed differences in unscaled callosal thickness may contribute to gender-specific cognition and behavior...
  58. pmc Anterior cingulate activation relates to local cortical thickness
    Catherine E Hegarty
    Jane and Terry Semel Institute of Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, USA
    Neuroreport 23:420-4. 2012
    ..No significant thickness-activation correlations were found in the prefrontal cortex. Correlations between cortical thickness and activation may occur only in certain brain regions...
  59. pmc Online resource for validation of brain segmentation methods
    David W Shattuck
    Laboratory of Neuro Imaging, David Geffen School of Medicine, University of California, Los Angeles, 635 Charles Young Drive South, NRB1, Suite 225, Los Angeles, California 90095, USA
    Neuroimage 45:431-9. 2009
    ..NeuroImage 13 (5), 856-876 (May) under several different program settings. Our results show that with proper parameter selection, all 3 algorithms can achieve satisfactory skull-stripping on the test data...
  60. pmc Enhanced brain connectivity in long-term meditation practitioners
    Eileen Luders
    Department of Neurology, UCLA School of Medicine, Los Angeles, CA 90095 7334, USA
    Neuroimage 57:1308-16. 2011
    ....
  61. pmc Genetic and environmental influences on cortical thickness among 14-year-old twins
    Yaling Yang
    Laboratory of Neuro Imaging, Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Neuroreport 23:702-6. 2012
    ....
  62. pmc Regional gray matter variation in male-to-female transsexualism
    Eileen Luders
    Department of Neurology, UCLA School of Medicine, Los Angeles, CA 90095 7334, USA
    Neuroimage 46:904-7. 2009
    ..These findings provide new evidence that transsexualism is associated with distinct cerebral pattern, which supports the assumption that brain anatomy plays a role in gender identity...
  63. pmc Why sex matters: brain size independent differences in gray matter distributions between men and women
    Eileen Luders
    Laboratory of Neuro Imaging, Department of Neurology, School of Medicine, University of California, Los Angeles, Los Angeles, California 90095 7334, USA
    J Neurosci 29:14265-70. 2009
    ..Altogether, our findings suggest that the observed increased regional GM volumes in female brains constitute sex-dependent redistributions of tissue volume, rather than individual adjustments attributable to brain size...
  64. pmc Localisation of increased prefrontal white matter in pathological liars
    Yaling Yang
    Department of Psychology, University of Southern California, Los Angeles, and David Geffen School of Medicine, CA 90089 1061, USA
    Br J Psychiatry 190:174-5. 2007
    ..This white matter increase may predispose some individuals to pathological lying...
  65. pmc A diffusion tensor imaging tractography algorithm based on Navier-Stokes fluid mechanics
    Nathan S Hageman
    Laboratory of Neuroimaging, University of California Los Angeles UCLA School of Medicine, Los Angeles, CA 90095, USA
    IEEE Trans Med Imaging 28:348-60. 2009
    ..Our method produced paths that were consistent with both known anatomy and directionally encoded color images of the DTI dataset...
  66. pmc The unique brain anatomy of meditation practitioners: alterations in cortical gyrification
    Eileen Luders
    Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine Los Angeles, CA, USA
    Front Hum Neurosci 6:34. 2012
    ..Due to the cross-sectional nature of this study, further research is necessary to determine the relative contribution of nature and nurture to links between cortical gyrification and meditation...
  67. pmc Cortex mapping reveals regionally specific patterns of genetic and disease-specific gray-matter deficits in twins discordant for schizophrenia
    Tyrone D Cannon
    Department of Psychology, University of California, 1285 Franz Hall, Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 99:3228-33. 2002
    ....
  68. pmc Regional brain volume reductions relate to facial dysmorphology and neurocognitive function in fetal alcohol spectrum disorders
    Florence F Roussotte
    Developmental Cognitive Neuroimaging Laboratory, Department of Neurology, University of California, Los Angeles 90095 7332, USA
    Hum Brain Mapp 33:920-37. 2012
    ....
  69. pmc Biomarkers to predict antidepressant response
    Andrew F Leuchter
    Semel Institute for Neuroscience and Human Behavior at UCLA, David Geffen School of Medicine at UCLA, Los Angeles, CA 90024, USA
    Curr Psychiatry Rep 12:553-62. 2010
    ..Once such biomarkers are validated, they could form the basis of new paradigms for antidepressant treatment selection...
  70. pmc Hippocampal morphology and distinguishing late-onset from early-onset elderly depression
    Martina Ballmaier
    Department of Psychiatry and Psychotherapy, Charite University Medicine, Campus Mitte, Berlin
    Am J Psychiatry 165:229-37. 2008
    ..This study used three-dimensional mapping techniques to identify regional hippocampal abnormalities in early- and late-onset depression. Neuropsychological correlates of hippocampal morphology were also investigated...
  71. pmc Mapping callosal morphology in early- and late-onset elderly depression: an index of distinct changes in cortical connectivity
    Martina Ballmaier
    Department of Psychiatry and Psychotherapy, Charite University Medicine, Campus Mitte, Berlin, Germany
    Neuropsychopharmacology 33:1528-36. 2008
    ..Patients with a late onset of depression may be at higher risk of illness progression and eventually dementia conversion than early-onset depression, with potentially important implications for research and therapy...
  72. pmc CSF sub-compartments in relation to plasma osmolality in healthy controls and in patients with first episode schizophrenia
    Handan Gunduz-Bruce
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Psychiatry Res 155:57-66. 2007
    ..These results suggest that plasma osmolality is related to ventricle size in healthy volunteers and that this physiological link is impaired in patients with first episode schizophrenia...

Research Grants2

  1. Mapping the MTL Memory System in Schizophrenia
    KATHERINE NARR; Fiscal Year: 2007
    ....