Narendra Narayana

Summary

Affiliation: University of Texas Health Science Center
Country: USA

Publications

  1. pmc Crystallographic analysis of a sex-specific enhancer element: sequence-dependent DNA structure, hydration, and dynamics
    Narendra Narayana
    Department of Biochemistry, Case Western Reserve University, Cleveland, OH 44106, USA
    J Mol Biol 385:469-90. 2009
  2. pmc Structure of the Q67H mutant of R67 dihydrofolate reductase-NADP+ complex reveals a novel cofactor binding mode
    N Divya
    Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio 44106, USA
    Protein Sci 16:1063-8. 2007
  3. ncbi Diabetes mellitus due to misfolding of a beta-cell transcription factor: stereospecific frustration of a Schellman motif in HNF-1alpha
    Narendra Narayana
    Department of Biochemistry, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106 4935, USA
    J Mol Biol 362:414-29. 2006
  4. ncbi High-resolution structure of a plasmid-encoded dihydrofolate reductase: pentagonal network of water molecules in the D2-symmetric active site
    Narendra Narayana
    Department of Biochemistry, Case Western Reserve University, Cleveland, OH 44106, USA
    Acta Crystallogr D Biol Crystallogr 62:695-706. 2006
  5. ncbi Interaction between the Z-type DNA duplex and 1,3-propanediamine: crystal structure of d(CACGTG)2 at 1.2 A resolution
    Narendra Narayana
    Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio 44106, USA
    Biochemistry 45:1200-11. 2006

Collaborators

Detail Information

Publications5

  1. pmc Crystallographic analysis of a sex-specific enhancer element: sequence-dependent DNA structure, hydration, and dynamics
    Narendra Narayana
    Department of Biochemistry, Case Western Reserve University, Cleveland, OH 44106, USA
    J Mol Biol 385:469-90. 2009
    ..We speculate that sites of intrinsic flexibility within a DNA control element provide hinges for its protein-directed reorganization in a transcriptional preinitiation complex...
  2. pmc Structure of the Q67H mutant of R67 dihydrofolate reductase-NADP+ complex reveals a novel cofactor binding mode
    N Divya
    Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio 44106, USA
    Protein Sci 16:1063-8. 2007
    ....
  3. ncbi Diabetes mellitus due to misfolding of a beta-cell transcription factor: stereospecific frustration of a Schellman motif in HNF-1alpha
    Narendra Narayana
    Department of Biochemistry, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106 4935, USA
    J Mol Biol 362:414-29. 2006
    ..Comparison of L- and D amino acid substitutions thus provides an example of the stereospecific control of an energy landscape by a helix-capping residue...
  4. ncbi High-resolution structure of a plasmid-encoded dihydrofolate reductase: pentagonal network of water molecules in the D2-symmetric active site
    Narendra Narayana
    Department of Biochemistry, Case Western Reserve University, Cleveland, OH 44106, USA
    Acta Crystallogr D Biol Crystallogr 62:695-706. 2006
    ..The geometrical shape, overall symmetry, local asymmetry and waters appear to dominate the binding of ligands, catalysis and inhibition...
  5. ncbi Interaction between the Z-type DNA duplex and 1,3-propanediamine: crystal structure of d(CACGTG)2 at 1.2 A resolution
    Narendra Narayana
    Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio 44106, USA
    Biochemistry 45:1200-11. 2006
    ..This structure provides a molecular basis for stabilizing AT base pairs incorporated into an alternating d(CG) sequence...