Sonia Napravnik

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. pmc Enrollment, retention, and visit attendance in the University of North Carolina Center for AIDS Research HIV clinical cohort, 2001-2007
    Chanelle J Howe
    Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina 27599 7435, USA
    AIDS Res Hum Retroviruses 26:875-81. 2010
  2. pmc Outcomes of second combination antiretroviral therapy regimens among HIV-infected persons in clinical care: a multicenter cohort study
    Sonia Napravnik
    Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7215, USA
    AIDS Res Hum Retroviruses 29:574-80. 2013
  3. pmc Quantifying the treatment efficacy of reverse transcriptase inhibitors: new analyses of clinical data based on within-host modeling
    Romulus Breban
    Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, CA 90024, USA
    BMC Public Health 9:S11. 2009
  4. pmc CD4 count at presentation for HIV care in the United States and Canada: are those over 50 years more likely to have a delayed presentation?
    Keri N Althoff
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD, 21205, USA
    AIDS Res Ther 7:45. 2010
  5. ncbi request reprint HIV-1 drug resistance evolution among patients on potent combination antiretroviral therapy with detectable viremia
    Sonia Napravnik
    School of Medicine, Division of Infectious Diseases, University of North Carolina at Chapel Hill, 27599, USA
    J Acquir Immune Defic Syndr 40:34-40. 2005
  6. ncbi request reprint Triple-class antiretroviral drug resistance: risk and predictors among HIV-1-infected patients
    Sonia Napravnik
    Division of Infectious Diseases, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    AIDS 21:825-34. 2007
  7. ncbi request reprint Factors associated with fewer visits for HIV primary care at a tertiary care center in the Southeastern U.S
    Sonia Napravnik
    Division of Infectious Diseases, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7215, USA
    AIDS Care 18:S45-50. 2006
  8. doi request reprint Quantification of CD4 responses to combined antiretroviral therapy over 5 years among HIV-infected children in Kinshasa, Democratic Republic of Congo
    Andrew Edmonds
    Department of Epidemiology, The University of North Carolina at Chapel Hill, McGavran Greenberg Hall, CB 7435, Chapel Hill, NC 27599 7435, USA
    J Acquir Immune Defic Syndr 61:90-8. 2012
  9. pmc Viremia copy-years predicts mortality among treatment-naive HIV-infected patients initiating antiretroviral therapy
    Michael J Mugavero
    Department of Medicine, Division of Infectious Diseases, University of Alabama, Birmingham, AL, USA
    Clin Infect Dis 53:927-35. 2011
  10. pmc The effect of highly active antiretroviral therapy on the survival of HIV-infected children in a resource-deprived setting: a cohort study
    Andrew Edmonds
    Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
    PLoS Med 8:e1001044. 2011

Detail Information

Publications40

  1. pmc Enrollment, retention, and visit attendance in the University of North Carolina Center for AIDS Research HIV clinical cohort, 2001-2007
    Chanelle J Howe
    Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina 27599 7435, USA
    AIDS Res Hum Retroviruses 26:875-81. 2010
    ..The UNC CFAR clinical cohort has ample enrollment with retention and visit attendance modestly influenced by factors such as disease severity...
  2. pmc Outcomes of second combination antiretroviral therapy regimens among HIV-infected persons in clinical care: a multicenter cohort study
    Sonia Napravnik
    Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7215, USA
    AIDS Res Hum Retroviruses 29:574-80. 2013
    ..The effectiveness of second cART regimens improved over calendar time and was independent of the anchor agent in the regimen...
  3. pmc Quantifying the treatment efficacy of reverse transcriptase inhibitors: new analyses of clinical data based on within-host modeling
    Romulus Breban
    Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, CA 90024, USA
    BMC Public Health 9:S11. 2009
    ..Current measures of the clinical efficacy of antiretroviral therapy (ART) in the treatment of HIV include the change in HIV RNA in the plasma and the gain in CD4 cells...
  4. pmc CD4 count at presentation for HIV care in the United States and Canada: are those over 50 years more likely to have a delayed presentation?
    Keri N Althoff
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD, 21205, USA
    AIDS Res Ther 7:45. 2010
    ..10%, respectively). Due to the increasing proportion, consistently lower CD4 counts, and more advanced HIV disease in adults ≥50-year-old at first presentation for HIV care, renewed HIV testing efforts are needed...
  5. ncbi request reprint HIV-1 drug resistance evolution among patients on potent combination antiretroviral therapy with detectable viremia
    Sonia Napravnik
    School of Medicine, Division of Infectious Diseases, University of North Carolina at Chapel Hill, 27599, USA
    J Acquir Immune Defic Syndr 40:34-40. 2005
    ....
  6. ncbi request reprint Triple-class antiretroviral drug resistance: risk and predictors among HIV-1-infected patients
    Sonia Napravnik
    Division of Infectious Diseases, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    AIDS 21:825-34. 2007
    ..HIV-1 triple-class antiretroviral drug resistance (TC-DR) may substantially limit therapeutic options and compromise clinical outcomes...
  7. ncbi request reprint Factors associated with fewer visits for HIV primary care at a tertiary care center in the Southeastern U.S
    Sonia Napravnik
    Division of Infectious Diseases, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7215, USA
    AIDS Care 18:S45-50. 2006
    ..Interventions including more intensive counseling and active outreach for newly HIV diagnosed individuals and support with obtaining health insurance and transportation may lead to improved outcomes...
  8. doi request reprint Quantification of CD4 responses to combined antiretroviral therapy over 5 years among HIV-infected children in Kinshasa, Democratic Republic of Congo
    Andrew Edmonds
    Department of Epidemiology, The University of North Carolina at Chapel Hill, McGavran Greenberg Hall, CB 7435, Chapel Hill, NC 27599 7435, USA
    J Acquir Immune Defic Syndr 61:90-8. 2012
    ..We sought to describe this relationship...
  9. pmc Viremia copy-years predicts mortality among treatment-naive HIV-infected patients initiating antiretroviral therapy
    Michael J Mugavero
    Department of Medicine, Division of Infectious Diseases, University of Alabama, Birmingham, AL, USA
    Clin Infect Dis 53:927-35. 2011
    ..We evaluated the cumulative effect of exposure to HIV replication on mortality following initiation of combination antiretroviral therapy (ART)...
  10. pmc The effect of highly active antiretroviral therapy on the survival of HIV-infected children in a resource-deprived setting: a cohort study
    Andrew Edmonds
    Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
    PLoS Med 8:e1001044. 2011
    ..Because most pediatric HIV occurs in low- and middle-income countries, our objective was to provide a first estimate of this effect among children living in a resource-deprived setting...
  11. pmc Incidence and timing of cancer in HIV-infected individuals following initiation of combination antiretroviral therapy
    Elizabeth L Yanik
    Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27599, USA
    Clin Infect Dis 57:756-64. 2013
    ..Cancer is an important cause of morbidity and mortality in individuals infected with human immunodeficiency virus (HIV), but patterns of cancer incidence after combination antiretroviral therapy (ART) initiation remain poorly characterized...
  12. pmc Temporal trends in presentation and survival for HIV-associated lymphoma in the antiretroviral therapy era
    Satish Gopal
    Departments of Medicine and Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    J Natl Cancer Inst 105:1221-9. 2013
    ..Lymphoma is the leading cause of cancer-related death among HIV-infected patients in the antiretroviral therapy (ART) era...
  13. pmc Hematologic, hepatic, renal, and lipid laboratory monitoring after initiation of combination antiretroviral therapy in the United States, 2000-2010
    Elizabeth L Yanik
    Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27517, USA
    J Acquir Immune Defic Syndr 63:216-20. 2013
    ..However, only 40% received 1 or more lipid tests. Monitoring was more frequent in specific subgroups, likely reflecting better clinic attendance or clinician perception of higher susceptibility to toxicities...
  14. ncbi request reprint Advanced immunosuppression at entry to HIV care in the southeastern United States and associated risk factors
    Cynthia L Gay
    The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    AIDS 20:775-8. 2006
    ..Male sex was an independent predictor in multivariable analysis. These results indicate an urgent need to increase HIV testing for earlier diagnosis in the southeastern USA...
  15. pmc HIV-1 viral load and phenotypic antiretroviral drug resistance assays based on reverse transcriptase activity in comparison to amplification based HIV-1 RNA and genotypic assays
    Sonia Napravnik
    Department of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States
    J Clin Virol 47:18-22. 2010
    ..Amplification based HIV-1 viral load and genotypic resistance assays are expensive, technologically complex and may be difficult to implement in resource limited settings. Inexpensive, simpler assays are urgently needed...
  16. ncbi request reprint Immunosuppression, hepatitis C infection, and acute renal failure in HIV-infected patients
    Nora Franceschini
    Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC 27514, USA
    J Acquir Immune Defic Syndr 42:368-72. 2006
    ..Low CD4 cell counts predict HIV-related morbidity and mortality and may be associated with acute renal failure (ARF)...
  17. doi request reprint HIV risk behaviors and sociodemographic features of HIV-infected Latinos residing in a new Latino settlement area in the Southeastern United States
    Ann M Dennis
    a Division of Infectious Diseases, University of North Carolina, Chapel Hill, NC, USA
    AIDS Care 25:1298-307. 2013
    ....
  18. pmc Late entry to HIV care among Latinos compared with non-Latinos in a southeastern US cohort
    Ann M Dennis
    Department of Medicine, Division of Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7030, USA
    Clin Infect Dis 53:480-7. 2011
    ..The southeastern United States is a rapidly growing Latino settlement area where ethnic disparities may contribute to late presentation to care...
  19. pmc Prevalence of transmitted antiretroviral drug resistance differs between acutely and chronically HIV-infected patients
    Elizabeth L Yanik
    Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27599, USA
    J Acquir Immune Defic Syndr 61:258-62. 2012
    ..AHI was associated with 1.9 times the prevalence of TDR (95% confidence intervals: 1.0 to 3.6) in multivariable analysis. AHI patients may represent a vanguard group that portends increasing TDR in the future...
  20. pmc Performance characteristics of the Cavidi ExaVir viral load assay and the ultra-sensitive P24 assay relative to the Roche Monitor HIV-1 RNA assay
    Paul Stewart
    The University of North Carolina at Chapel Hill, Department of Biostatistics, Chapel Hill, NC 27599 7420, USA paul
    J Clin Virol 49:198-204. 2010
    ....
  21. pmc Anti-retroviral therapy reduces incident tuberculosis in HIV-infected children
    Andrew Edmonds
    The University of North Carolina at Chapel Hill, Department of Epidemiology, Chapel Hill, NC, USA
    Int J Epidemiol 38:1612-21. 2009
    ..We aimed to estimate the effect of anti-retroviral therapy (ART) on incident tuberculosis (TB) in a cohort of HIV-infected children...
  22. pmc Decreasing excess mortality of HIV-infected patients initiating antiretroviral therapy: comparison with mortality in general population in China, 2003-2009
    Hao Zhu
    Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC Division of Treatment and Care, National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China Division of Infectious Diseases, School of Medicine, University of North Carolina, Chapel Hill, NC and Division of Infectious Diseases, Beijing Ditan Hospital Capital Medical University, Beijing, China
    J Acquir Immune Defic Syndr 63:e150-7. 2013
    ..To evaluate excess mortality across calendar time comparing HIV-infected patients receiving combination antiretroviral therapy (cART) with the general Chinese population...
  23. doi request reprint Ezetimibe alone reduces low-density lipoprotein cholesterol in HIV-infected patients receiving combination antiretroviral therapy
    David A Wohl
    University of North Carolina, Chapel Hill, NC 27599, USA
    Clin Infect Dis 47:1105-8. 2008
    ..5% (+4 mg/dL) with ezetimibe treatment and placebo, respectively (P = .04). Ezetimibe was safe and effective in reducing low-density lipoprotein cholesterol and is an option for patients who cannot tolerate treatment with a statin...
  24. pmc Joint effects of alcohol consumption and high-risk sexual behavior on HIV seroconversion among men who have sex with men
    Petra M Sander
    Department of Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, NC, USA
    AIDS 27:815-23. 2013
    ..To estimate the effects of alcohol consumption and number of unprotected receptive anal intercourse partners on HIV seroconversion while appropriately accounting for time-varying confounding...
  25. pmc Phylogenetic insights into regional HIV transmission
    Ann M Dennis
    Division of Infectious Diseases, University of North Carolina, Chapel Hill, North Carolina 27599 7030, USA
    AIDS 26:1813-22. 2012
    ..We integrated phylogenetic analyses with clinical data to reveal trends in local HIV transmission...
  26. pmc Copy-years viremia as a measure of cumulative human immunodeficiency virus viral burden
    Stephen R Cole
    Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC 27599 7435, USA
    Am J Epidemiol 171:198-205. 2010
    ..Copy-years viremia, a novel measure of cumulative viral burden, may provide prognostic information beyond traditional single measures of viremia...
  27. pmc Invasive cervical cancer risk among HIV-infected women: a North American multicohort collaboration prospective study
    Alison G Abraham
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY Division of Infectious Diseases, School of Medicine, Vanderbilt University, Nashville, TN Division of Research, Kaiser Permanente Northern California, Oakland, CA Division of Infectious Diseases, University of Alabama, Birmingham, AL Ontario Treatment Network, University of Toronto, Toronto, ON, Canada Division of Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC Department of Medicine, Johns Hopkins University, Baltimore, MD Department of Medicine, Division of Infectious Diseases Chronic Viral Illness Service, McGill University, Montreal, Quebec, Canada Department of Medicine, University of Washington, Seattle, WA Department of Health Sciences, British Columbia Centre for Excellence and HIV AIDS, Simon Fraser University, Vancouver, British Columbia, Canada Department of Clinical Pharmacy and Medicine, University of California, San Francisco, CA Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD Department of Medicine, University of Calgary, Calgary
    J Acquir Immune Defic Syndr 62:405-13. 2013
    ..Few reported prospective cohort studies have characterized the incidence of invasive cervical cancer (ICC) in HIV-infected women...
  28. pmc Incidence and clinical features of cerebrovascular disease among HIV-infected adults in the Southeastern United States
    Michael J Vinikoor
    Department of Medicine, University of North Carolina, Chapel Hill, NC 27599 7030, USA
    AIDS Res Hum Retroviruses 29:1068-74. 2013
    ..Prevention of CVEs in this population will require modification of traditional CVD risk factors and early, effective treatment of HIV infection...
  29. pmc Risk factors for tuberculosis after highly active antiretroviral therapy initiation in the United States and Canada: implications for tuberculosis screening
    Timothy R Sterling
    Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    J Infect Dis 204:893-901. 2011
    ..Identifying factors associated with developing tuberculosis after HAART initiation could focus screening efforts...
  30. ncbi request reprint Effect of hepatitis C coinfection on discontinuation and modification of initial HAART in primary HIV care
    Dina Hooshyar
    Division of Infectious Diseases, School of Medicine, University of North Carolina at Chapel Hill, North Carolina 27599 7215, USA
    AIDS 20:575-83. 2006
    ..To estimate the effect of hepatitis C (HCV) coinfection on time to first occurrence of either discontinuation or modification of initial HAART among previously antiretroviral therapy-naive HIV-infected patients...
  31. ncbi request reprint Incidence and etiology of acute renal failure among ambulatory HIV-infected patients
    Nora Franceschini
    Division of Nephrology and Hypertension, School of Medicine, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Kidney Int 67:1526-31. 2005
    ..Its incidence and causes have not been studied since the introduction of highly active antiretroviral therapy (HAART) in HIV ambulatory patients...
  32. ncbi request reprint HIV and parasitic infection and the effect of treatment among adult outpatients in Malawi
    Mina C Hosseinipour
    University of North Carolina Project, Lilongwe, Malawi
    J Infect Dis 195:1278-82. 2007
    ..Successful treatment of parasitic infections had no effect on HIV RNA levels. Although common, parasitic infections did not impact HIV RNA levels...
  33. doi request reprint The effect of tuberculosis treatment on virologic and CD4+ cell count response to combination antiretroviral therapy: a systematic review
    Heidi M Soeters
    aDepartment of Epidemiology bDivision of Infectious Diseases cCenter for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    AIDS 28:245-55. 2014
    ..To determine the impact of tuberculosis (TB) treatment at the time of combination antiretroviral therapy (cART) initiation on virologic and CD4 cell count response to cART...
  34. pmc Comparative effectiveness of initial antiretroviral therapy regimens: ACTG 5095 and 5142 clinical trials relative to ART-CC cohort study
    Michael J Mugavero
    Division of Infectious Disease, Department of Medicine, University of Alabama, Birmingham, AL, USA
    J Acquir Immune Defic Syndr 58:253-60. 2011
    ....
  35. pmc Self-report of current and prior antiretroviral drug use in comparison to the medical record among HIV-infected patients receiving primary HIV care
    Emily Suzanne Brouwer
    Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA
    Pharmacoepidemiol Drug Saf 20:432-9. 2011
    ..In this study we assessed the ability of HIV-infected patients receiving care in a university infectious diseases clinic to accurately recall current and past ARVs...
  36. ncbi request reprint Randomized study of the safety and efficacy of fish oil (omega-3 fatty acid) supplementation with dietary and exercise counseling for the treatment of antiretroviral therapy-associated hypertriglyceridemia
    David A Wohl
    Division of Infectious Diseases, University of North Carolina, Chapel Hill, NC 27599, USA
    Clin Infect Dis 41:1498-504. 2005
    ..Whether omega-3 fatty acid supplementation can reduce hypertriglyceridemia associated with antiretroviral therapy is not known...
  37. pmc Recent cancer incidence trends in an observational clinical cohort of HIV-infected patients in the US, 2000 to 2011
    Elizabeth L Yanik
    Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, 715 Mary Ellen Jones Building, Chapel Hill, NC, USA
    Infect Agent Cancer 8:18. 2013
    ..We assessed changes in the distribution of cancer types and incidence trends among HIV-infected patients in North Carolina up until 2011...
  38. ncbi request reprint Gender difference in HIV RNA levels: a meta-analysis of published studies
    Sonia Napravnik
    School of Public Health, Department of Epidemiology, Division of Infectious Diseases, University of North Carolina at Chapel Hill, 27599, USA
    J Acquir Immune Defic Syndr 31:11-9. 2002
    ....
  39. doi request reprint Frequency of HIV-related medication errors and associated risk factors in hospitalized patients
    Sonak D Pastakia
    Department of Pharmacy Practice, School of Pharmacy and Pharmaceutical Sciences, Purdue University, Indianapolis, IN 46202, USA
    Ann Pharmacother 42:491-7. 2008
    ..Retrospective studies of hospitalized HIV-infected patients have noted a high occurrence of drug-related errors, ranging from 5% to 30%...
  40. ncbi request reprint Substance abuse and symptoms of mental illness among HIV-positive persons in the Southeast
    Kathryn Whetten
    Department of Public Policy, Duke University, Durham, NC, USA
    South Med J 98:9-14. 2005
    ..Mental illness and substance abuse have been consistently associated with poor HIV-medication adherence and other negative health outcomes...

Research Grants1