Minelva R Nanton
Affiliation: University of Minnesota
- Cutting edge: B cells are essential for protective immunity against Salmonella independent of antibody secretionMinelva R Nanton
Department of Pediatric Infectious Disease, Center for Infectious Diseases and Microbiology Translational Research, University of Minnesota Medical School Twin Cities, Minneapolis, MN 55455, USA
J Immunol 189:5503-7. 2012..Taken together, these data suggest that the primary role of B cells in acquired immunity to Salmonella is via the development of protective T cell immunity...
- Innate immune activation during Salmonella infection initiates extramedullary erythropoiesis and splenomegalyAmy Jackson
Center for Infectious Diseases and Microbiology Translational Research, Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Minnesota Medical School, Minneapolis, MN 55455, USA
J Immunol 185:6198-204. 2010..These data indicate that early innate immunity to Salmonella initiates marked splenic erythropoiesis and may hinder bacterial clearance...
- Selective culling of high avidity antigen-specific CD4+ T cells after virulent Salmonella infectionJames M Ertelt
Department of Pediatrics, University of Minnesota School of Medicine, Center for Microbiology and Infectious Disease Translational Research, Minneapolis, MN 55455, USA
Immunology 134:487-97. 2011..Hence, virulent Salmonella triggers the selective culling of high avidity activated CD4+ T-cell subsets, which re-shapes the repertoire of antigen-specific T cells that persist later after infection...