Research Topics
| Ruria NambaSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Selective estrogen receptor modulators inhibit growth and progression of premalignant lesions in a mouse model of ductal carcinoma in situRuria Namba
Department of Pathology and Laboratory Medicine, School of Medicine, University of California, Davis, Sacramento, CA, USA
Breast Cancer Res 7:R881-9. 2005..We studied the ovarian-hormone-responsiveness of one of the lines with a particular focus on the effects of two related SERMs, tamoxifen and ospemifene...
Heterogeneity of mammary lesions represent molecular differencesRuria Namba
Department of Pathology and Laboratory Medicine, School of Medicine, University of California at Davis, Sacramento, CA 95817, USA
BMC Cancer 6:275. 2006..Each MIN-O line has distinguishable morphologies, metastatic potentials and estrogen dependencies...
Polyomavirus middle T-induced mammary intraepithelial neoplasia outgrowths: single origin, divergent evolution, and multiple outcomesJeannie E Maglione
Department of Medicine, UCSD Cancer Center, School of Medicine, University of California-San Diego, La Jolla, CA, USA
Mol Cancer Ther 3:941-53. 2004..These lines provide an opportunity to study the full range of events occurring secondary to PyV-mT expression in the mammary gland...
Rapamycin inhibits growth of premalignant and malignant mammary lesions in a mouse model of ductal carcinoma in situRuria Namba
Department of Pathology and Laboratory Medicine, School of Medicine, University of California, Davis, Sacramento, CA 95817, USA
Clin Cancer Res 12:2613-21. 2006..Although the inhibitory effect of rapamycin was striking, rapamycin treatment did not completely obliterate the lesions...
Syngeneic mouse mammary carcinoma cell lines: two closely related cell lines with divergent metastatic behaviorAlexander D Borowsky
Department of Medical Pathology and Laboratory Medicine, UC Davis School of Medicine, Sacramento, CA 95817, USA
Clin Exp Metastasis 22:47-59. 2005..Therefore, these two cell lines provide a stable, reproducible resource for the study of metastasis modulators, AKT molecular pathway interactions, and gene target and marker discovery...
Molecular characterization of the transition to malignancy in a genetically engineered mouse-based model of ductal carcinoma in situRuria Namba
Department of Pathology and Laboratory Medicine, School of Medicine, University of California-Davis, Sacramento, California 95817, USA
Mol Cancer Res 2:453-63. 2004..With consistent tumor latency and molecular profiles, this model provides an experimental platform that can be used to assess functional genomics and molecular pharmacology and to test promising chemoprevention strategies...
