Research Topics
| B K NallamothuSummaryAffiliation: University of Michigan Country: USA Publications
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Publications
Contemporary evidence: baseline data from the D2B AllianceElizabeth H Bradley
Section of Health Policy and Administration, School of Public Health, Yale University School of Medicine, New Haven, Connecticut, USA
BMC Res Notes 1:23. 2008..This study presents data on (1) the prevalence of evidence-based strategies in U.S. hospitals that participated in the D2B Alliance and (2) identifies key hospital characteristics associated with their use...- Hospital variation in transfusion and infection after cardiac surgery: a cohort studyMary A M Rogers
Division of General Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA
BMC Med 7:37. 2009..Concomitant with this re-examination have been reports showing variability in the use of specific blood components. This investigation was designed to assess hospital variation in blood use and outcomes in cardiac surgery patients... - Skilled care requirements for elderly patients after coronary artery bypass graftingBrahmajee K Nallamothu
Health Services Research and Development Center of Excellence, Ann Arbor Veterans Affairs Medical Center, Ann Arbor, Michigan 48109, USA
J Am Geriatr Soc 53:1133-7. 2005..To examine the extent to which elderly individuals use various skilled care facilities after coronary artery bypass grafting (CABG)... - Impact of patient risk on the hospital volume-outcome relationship in coronary artery bypass graftingBrahmajee K Nallamothu
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, 48109 0366, USA
Arch Intern Med 165:333-7. 2005..We assessed (1) whether in-hospital mortality rates differ across lower- and higher-volume hospitals by expected surgical risk and (2) whether high-risk patients are more likely to undergo CABG at low-volume centers... - Coronary revascularization at specialty cardiac hospitals and peer general hospitals in black Medicare beneficiariesBrahmajee K Nallamothu
Health Services Research and Development Center of Excellence, Ann Arbor VA Medical Center, Ann Arbor, Mich, USA
Circ Cardiovasc Qual Outcomes 1:116-22. 2008..Critics have raised concerns that specialty cardiac hospitals exacerbate racial disparities in cardiovascular care, but empirical data are limited... - Clinical problem-solving. Double jeopardyBrahmajee K Nallamothu
Health Services Research and Development Center of Excellence, Ann Arbor Veterans Affairs Medical Center, and the Department of Internal Medicine, University of Michigan, Ann Arbor, USA
N Engl J Med 353:75-80. 2005 - Opening of specialty cardiac hospitals and use of coronary revascularization in medicare beneficiariesBrahmajee K Nallamothu
VA Health Services Research and Development Center of Excellence, Ann Arbor, Mich, USA
JAMA 297:962-8. 2007..Although proponents argue that specialty cardiac hospitals provide high-quality cost-efficient care, strong financial incentives for physicians at these facilities could result in greater procedure utilization... - Acute myocardial infarction and congestive heart failure outcomes at specialty cardiac hospitalsBrahmajee K Nallamothu
Health Services Research and Development Center of Excellence, Ann Arbor VA Medical Center, and Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Mich, USA
Circulation 116:2280-7. 2007..Outcomes of patients with acute myocardial infarction (AMI) and congestive heart failure (CHF) at specialty cardiac hospitals are uncertain... - Beyond the randomized clinical trial: the role of effectiveness studies in evaluating cardiovascular therapiesBrahmajee K Nallamothu
Health Services Research and Development Center of Excellence, Ann Arbor VA Medical Center, Ann Arbor, MI, USA
Circulation 118:1294-303. 2008 - Recent trends in hospital utilization for acute myocardial infarction and coronary revascularization in the United StatesBrahmajee K Nallamothu
VA Health Services Research and Development Center of Excellence, Ann Arbor VA Medical Center, Ann Arbor, Michigan, USA
Am J Cardiol 99:749-53. 2007..In conclusion, the number and rates of hospitalization for AMI and coronary revascularization in the United States are decreasing... - Broken bodies, broken hearts? Limitations of the trauma system as a model for regionalizing care for ST-elevation myocardial infarction in the United StatesBrahmajee K Nallamothu
Health Services Research and Development Center of Excellence, VA Medical Center, Ann Arbor, MI, USA
Am Heart J 152:613-8. 2006..In this article, we briefly review the current status of trauma systems in the United States and describe why the regionalization of STEMI care may require different methods of healthcare organization... - Operator experience and carotid stenting outcomes in Medicare beneficiariesBrahmajee K Nallamothu
Center for Healthcare Outcomes and Policy, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
JAMA 306:1338-43. 2011..Although the efficacy of carotid stenting has been established in clinical trials, outcomes of the procedure based on operator experience are less certain in clinical practice... - Is acetylcysteine effective in preventing contrast-related nephropathy? A meta-analysisBrahmajee K Nallamothu
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan 48109 0311, USA
Am J Med 117:938-47. 2004..Although previous meta-analyses have concluded that acetylcysteine is beneficial, the recent availability of additional trials calls for reassessment of current evidence... - Homocyst(e)ine and coronary heart disease: pharmacoeconomic support for interventions to lower hyperhomocyst(e)inaemiaBrahmajee K Nallamothu
Department of Internal Medicine, University of Michigan Medical School, B1F245 University Hospital, Ann Arbor, MI 49109 0022, USA
Pharmacoeconomics 20:429-42. 2002.... - Potential clinical and economic effects of homocyst(e)ine loweringB K Nallamothu
Division of General Medicine, University of Michigan Medical Center, 3116 Taubman Center, Ann Arbor, MI 48109 0376, USA
Arch Intern Med 160:3406-12. 2000..However, the benefits expected from lowering homocyst(e)ine levels with folic acid and vitamin B(12) supplementation have yet to be demonstrated in clinical trials... - Coronary artery bypass grafting in octogenarians: clinical and economic outcomes at community-based healthcare facilitiesBrahmajee K Nallamothu
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, USA
Am J Manag Care 8:749-55. 2002..Results of recent studies from high-volume academic centers suggest that coronary artery bypass grafting (CABG) is becoming safer to perform in octogenarians. Similar data from community-based facilities do not exist... - Electron-beam computed tomography in the diagnosis of coronary artery disease: a meta-analysisB K Nallamothu
B1F245, Division of General Medicine, University Hospital, Ann Arbor, MI 48109 0022, USA
Arch Intern Med 161:833-8. 2001..Before its clinical use is justified, however, the overall accuracy of EBCT must be better defined... - Door-to-balloon times in hospitals within the get-with-the-guidelines registry after initiation of the door-to-balloon (D2B) AllianceBrahmajee K Nallamothu
Ann Arbor VA Medical Center, Michigan, USA
Am J Cardiol 103:1051-5. 2009..These improvements were broad and not limited to hospitals that joined the D2B Alliance... - Coronary artery bypass grafting in Native Americans: a higher risk of death compared to other ethnic groups?B K Nallamothu
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor 48109 0022, USA
J Gen Intern Med 16:554-9. 2001..While the efficacy and safety of coronary artery bypass grafting (CABG) has been established in several clinical trials, little is known about its outcomes in Native Americans... - Relation between hospital specialization with primary percutaneous coronary intervention and clinical outcomes in ST-segment elevation myocardial infarction: National Registry of Myocardial Infarction-4 analysisBrahmajee K Nallamothu
Health Services Research and Development Center of Excellence, Ann Arbor VA Medical Center, Ann Arbor, Michigan, USA
Circulation 113:222-9. 2006..CONCLUSIONS: Greater specialization with PPCI is associated with lower in-hospital mortality and shorter door-to-balloon times in STEMI patients treated with PPCI... - The role of hospital volume in coronary artery bypass grafting: is more always better?B K Nallamothu
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan 48109-0366, USA
J Am Coll Cardiol 38:1923-30. 2001..CONCLUSIONS: Targeted regionalization might be a feasible strategy for balancing the clinical benefits of regionalization with patients' desires for choice and access... - Association of door-to-balloon time and mortality in patients > or =65 years with ST-elevation myocardial infarction undergoing primary percutaneous coronary interventionSaif S Rathore
Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
Am J Cardiol 104:1198-203. 2009.... - Syncope in acute aortic dissection: diagnostic, prognostic, and clinical implicationsBrahmajee K Nallamothu
University of Michigan Medical School, Ann Arbor, Michigan, USA
Am J Med 113:468-71. 2002..If these complications are excluded, syncope alone does not appear to increase the risk of death independently... - Primary percutaneous coronary intervention expansion to hospitals without on-site cardiac surgery in Michigan: a geographic information systems analysisJeremy W Buckley
University of Michigan Medical School, Ann Arbor, MI 48109, USA
Am Heart J 155:668-72. 2008..In 2005, Michigan expanded primary percutaneous coronary intervention (P-PCI) capability to 12 hospitals without on-site cardiac surgery. We determined the potential impact of this expansion on geographic access to P-PCI for patients... - Allogeneic blood transfusions explain increased mortality in women after coronary artery bypass graft surgeryMary A M Rogers
Division of General Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109 0429, USA
Am Heart J 152:1028-34. 2006..Because allogeneic blood transfusions are more common in women and have been associated with immunomodulation, the impact of transfusion on sex differences in infection and mortality was examined... - Trends in acute reperfusion therapy for ST-segment elevation myocardial infarction from 1999 to 2006: we are getting better but we have got a long way to goKim A Eagle
University of Michigan Cardiovascular Center, Ann Arbor, MI 48109 0477, USA
Eur Heart J 29:609-17. 2008..Many patients who are eligible for acute reperfusion therapy receive it after substantial delays or not at all. We wanted to determine whether over the years more patients are receiving reperfusion therapy... - Times to treatment in transfer patients undergoing primary percutaneous coronary intervention in the United States: National Registry of Myocardial Infarction (NRMI)-3/4 analysisBrahmajee K Nallamothu
Health Services Research and Development Center for Excellence, Ann Arbor Veterans Affairs Medical Center, Ann Arbor, Mich, USA
Circulation 111:761-7. 2005..For the full benefits of primary PCI to be realized in transfer patients, improved systems are urgently needed to minimize total door-to-balloon times... - Safety of carotid artery stenting for symptomatic carotid artery disease: a meta-analysisHitinder S Gurm
Division of Cardiovascular Medicine, University of Michigan Health System, 2A 394, 1500 E Medical Center Drive, Ann Arbor, MI 48109 0311, USA
Eur Heart J 29:113-9. 2008..We performed a meta-analysis to systematically evaluate currently available data by comparing CAS with CEA in patients with symptomatic carotid artery disease... - Vasodilator therapy in patients with aortic insufficiency: a systematic reviewAli Mahajerin
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109 0366, USA
Am Heart J 153:454-61. 2007..The use of vasodilators to improve long-term outcomes in asymptomatic patients with chronic aortic insufficiency (AI) is controversial... - Incremental benefit and cost-effectiveness of high-dose statin therapy in high-risk patients with coronary artery diseasePaul S Chan
University of Michigan Department of Internal Medicine, Ann Arbor, MI, USA
Circulation 115:2398-409. 2007..However, the actual benefit and cost-effectiveness of high-dose statin therapy are unknown... - Acute reperfusion therapy in ST-elevation myocardial infarction from 1994-2003Brahmajee K Nallamothu
Health Services Research and Development Center of Excellence, Ann Arbor VA Medical Center, Ann Arbor, Mich, USA
Am J Med 120:693-9. 2007..Appropriate utilization of acute reperfusion therapy is not a national performance measure for ST-elevation myocardial infarction at this time, and the extent of its contemporary use among ideal patients is unknown... - Commentary: the role of percutaneous coronary intervention in ST-segment-elevation myocardial infarctionEric R Bates
CVC Cardiovascular Medicine, 1500 E Medical Center Dr, Ann Arbor, MI 48109-5869, USA
Circulation 118:567-73. 2008 - The University of Michigan Specialist-Hospitalist Allied Research Program: jumpstarting hospital medicine researchScott A Flanders
Hospitalist Program, Division of General Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA
J Hosp Med 3:308-13. 2008..Ideally, a successful hospital-based clinical research program will need to partner hospitalists with specialists... - Thirty-day outcomes in Medicare patients with heart failure at heart transplant centersScott L Hummel
Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Mich 48109 5853, USA
Circ Heart Fail 3:244-52. 2010..However, their overall performance has not previously been evaluated in a broad population of elderly patients with heart failure, many of whom are not transplant candidates... - Percutaneous coronary intervention versus fibrinolytic therapy in acute myocardial infarction: is timing (almost) everything?Brahmajee K Nallamothu
Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan 48109-0366, USA
Am J Cardiol 92:824-6. 2003..Interventional cardiology laboratories endeavoring to achieve the benefits of primary percutaneous coronary intervention seen in randomized clinical trials should aim to match their short door-to-balloon times... - Interhospital transfers among Medicare beneficiaries admitted for acute myocardial infarction at nonrevascularization hospitalsTheodore J Iwashyna
Department of Internal Medicine, University of Michigan Medical School, 300 North Ingalls, Ann Arbor, MI 48109 5419, USA
Circ Cardiovasc Qual Outcomes 3:468-75. 2010.... - Use of medical imaging procedures with ionizing radiation in children: a population-based studyAdam L Dorfman
Department of Pediatrics, Division of Pediatric Cardiology, University of Michigan Health Systems, 1500 E Medical Center Drive, Ann Arbor, MI 48109, USA
Arch Pediatr Adolesc Med 165:458-64. 2011..To determine population-based rates of the use of diagnostic imaging procedures with ionizing radiation in children, stratified by age and sex... - Are changes in carotid intima-media thickness related to risk of nonfatal myocardial infarction? A critical review and meta-regression analysisZachary D Goldberger
Department of Internal Medicine, Division of Cardiology, University of Michigan Health System, Ann Arbor, MI, USA
Am Heart J 160:701-14. 2010..However, it remains unclear whether changes in CIMT that result from these therapies correlate with nonfatal myocardial infarction (MI)... - When zebras run with horses: the diagnostic dilemma of acute aortic dissection complicated by myocardial infarctionBrahmajee K Nallamothu
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA
J Interv Cardiol 15:297-9. 2002..in this comment on two key aspects of the case: (1) How commonly do acute aortic dissections lead to myocardial ischemia and MI? and (2) When should clinicians consider ruling out acute aortic dissection in the setting of acute MI?.. - Effect of statin use in patients with acute coronary syndromes and a serum low-density lipoprotein<or=80 mg/dlThomas T Tsai
Department of Internal Medicine, Division of Cardiology, University of Michigan Medical Center, Ann Arbor, Michigan, USA
Am J Cardiol 96:1491-3. 2005..0% vs 9.5%, p=0.005). These results suggest that patients who have an acute coronary syndrome and a low-density lipoprotein cholesterol level<or=80 mg/dl in the absence of statin therapy may benefit from such therapy at discharge... - Contribution of infection to increased mortality in women after cardiac surgeryMary A M Rogers
Division of General Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109 0429, USA
Arch Intern Med 166:437-43. 2006..Explanations for this sex difference are controversial. The objective of this study was to assess whether infection contributes to the increased risk of mortality in women... - Spontaneous hemopericardium in a patient with hemophilia B: a case report and review of the literatureDee Dee Wang
University of Michigan Health System, Ann Arbor, MI 48109 5368, USA
J Invasive Cardiol 20:E296-300. 2008..We review the clinical challenges raised by this group of patients undergoing cardiac procedures and present a stepwise approach to optimal management during the periprocedural period... - Racial differences in admissions to high-quality hospitals for coronary heart diseaseIoana Popescu
Department of Internal Medicine, The University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52240, USA
Arch Intern Med 170:1209-15. 2010..Research increasingly shows that blacks with coronary heart disease (CHD) are treated at lower-quality hospitals. Little is known about racial differences in admission to high-quality hospitals... - Area socioeconomic status and mortality after coronary artery bypass graft surgery: the role of hospital volumeCatherine Kim
Division of General Internal Medicine, Department of Medicine, University of Michigan, Ann Arbor, MI, USA
Am Heart J 154:385-90. 2007..Individuals of low socioeconomic status (SES) have reduced access to coronary artery bypass graft surgery (CABG). It is unknown if low-SES CABG patients have reduced access to hospitals with better outcomes... - Differences in patient survival after acute myocardial infarction by hospital capability of performing percutaneous coronary intervention: implications for regionalizationJersey Chen
Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520 8017, USA
Arch Intern Med 170:433-9. 2010..Whether regionalization will improve outcomes depends in part on the magnitude of existing differences in outcomes between PCI and non-PCI hospitals within the same health care region... - Regionalization of ST-segment elevation acute coronary syndromes care: putting a national policy in proper perspectiveSaif S Rathore
Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA
J Am Coll Cardiol 47:1346-9. 2006..Clearer evidence of the benefits and discussion of potential harms are needed before adopting a national STEMI regionalization policy... - Prognostic implication of activated partial thromboplastin time after reteplase or half-dose reteplase plus abciximab: results from the GUSTO-V trialBrahmajee K Nallamothu
University of Michigan Medical Center, Ann Arbor, MI, USA
Eur Heart J 26:1506-12. 2005..CONCLUSION: Peak aPTT levels <50 s and >70 s are associated with worse clinical outcomes in the modern era of fibrinolytic therapy; these relationships are different in patients receiving standard reteplase vs. combination therapy... - Driving times and distances to hospitals with percutaneous coronary intervention in the United States: implications for prehospital triage of patients with ST-elevation myocardial infarctionBrahmajee K Nallamothu
Health Services Research and Development Center of Excellence, Ann Arbor VA Medical Center, Ann Arbor, Michigan, USA
Circulation 113:1189-95. 2006.... - Rates of infection for single-lumen versus multilumen central venous catheters: a meta-analysisCameron Dezfulian
Department of Internal Medicine, University of Michigan, Ann Arbor, USA
Crit Care Med 31:2385-90. 2003..The slight increase in infectious risk when using multilumen catheters is likely offset by their improved convenience, thereby justifying the continued use of multilumen vascular catheters... - Potential impact of the HIPAA privacy rule on data collection in a registry of patients with acute coronary syndromeDavid Armstrong
Division of Cardiovascular Medicine, Department of Internal Medicine, and the Cardiovascular Center of the University of Michigan Health System, and Health Services Research and Development Center of Excellence, Ann Arbor, USA
Arch Intern Med 165:1125-9. 2005..50 annually thereafter. CONCLUSIONS: The HIPAA Privacy Rule significantly decreases the number of patients available for outcomes research and introduces selection bias in data collection for patient registries... - Prognostic implication of troponin I elevation after percutaneous coronary interventionBrahmajee K Nallamothu
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA
Am J Cardiol 91:1272-4. 2003 - Current role of sodium bicarbonate-based preprocedural hydration for the prevention of contrast-induced acute kidney injury: a meta-analysisShea E Hogan
Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI 48109 5853, USA
Am Heart J 156:414-21. 2008..The purpose of this meta-analysis is to compare the effectiveness of normal saline (NS) versus sodium bicarbonate hydration (NaHCO(3)) for prevention of contrast-induced AKI... - Time to treatment in primary percutaneous coronary interventionBrahmajee K Nallamothu
Health Services Research and Development Center of Excellence, Ann Arbor Veterans Affairs Medical Center, and the Department of Internal Medicine, Division of Cardiovascular Disease, University of Michigan Medical School, Ann Arbor, USA
N Engl J Med 357:1631-8. 2007 - Meta-analysis of randomized trials of drug-eluting stents versus bare metal stents in patients with diabetes mellitusThomas F Boyden
University Michigan Medical School, Ann Arbor VA Medical Center, Ann Arbor, Michigan, USA
Am J Cardiol 99:1399-402. 2007..001). DES use is associated with a marked decrease in in-stent restenosis and target lesion revascularization in patients with diabetes. In conclusion, the analysis supports the current widespread use of DESs in these high-risk patients... - Primary percutaneous coronary intervention versus fibrinolytic therapy in acute myocardial infarction: does the choice of fibrinolytic agent impact on the importance of time-to-treatment?Brahmajee K Nallamothu
Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan Medical Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0366, USA
Am J Cardiol 94:772-4. 2004..When a substantial delay in initiating primary PCI is likely, reperfusion therapy with second- or third-generation fibrinolytic agents should be strongly considered... - Long-term prognostic implication of extracardiac vascular disease in patients undergoing percutaneous coronary interventionBrahmajee K Nallamothu
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA
Am J Cardiol 92:964-6. 2003..0 to 2.0, p = 0.029). When extracardiac vascular disease was separated into cerebrovascular disease and peripheral vascular disease, cerebrovascular disease was less common but was associated with a trend towards worse survival... - Should coronary artery bypass grafting be regionalized?Brahmajee K Nallamothu
Health Services Research and Development Center of Excellence, Ann Arbor Veterans Affairs Medical Center, Ann Arbor, Michigan, USA
Ann Thorac Surg 80:1572-81. 2005 - An early invasive strategy versus ischemia-guided management after fibrinolytic therapy for ST-segment elevation myocardial infarction: a meta-analysis of contemporary randomized controlled trialsHarindra C Wijeysundera
Department of Medicine, Division of Cardiology, Schulich Heart Center, Sunnybrook Health Sciences Center, University of Toronto, Toronto, Ontario, Canada
Am Heart J 156:564-572, 572.e1-2. 2008.... - Coronary artery bypass surgery, hospital volume, and riskBrahmajee K Nallamothu
Circulation 108:e6-7; author reply e6-7. 2003 - Time-to-reperfusion in patients undergoing interhospital transfer for primary percutaneous coronary intervention in the U.S: an analysis of 2005 and 2006 data from the National Cardiovascular Data RegistryAnjan Chakrabarti
J Am Coll Cardiol 51:2442-3. 2008 - Do physicians examine patients in contact isolation less frequently? A brief reportSanjay Saint
Ann Arbor Department of Veterans Affairs Medical Center, USA
Am J Infect Control 31:354-6. 2003..49; 95% confidence interval, 0.30-0.79; P <.001). DISCUSSION: Attending physicians are about half as likely to examine patients in contact isolation compared with patients not in contact isolation... - Volume and outcomeBrahmajee K Nallamothu
N Engl J Med 347:693-6; author reply 693-6. 2002 - Hospital quality for acute myocardial infarction: correlation among process measures and relationship with short-term mortalityElizabeth H Bradley
Department of Epidemiology and Public Health, Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, Conn 06520-8088, USA
JAMA 296:72-8. 2006..Multiple measures that reflect a variety of processes and also outcomes, such as risk-standardized mortality rates, are needed to more fully characterize hospital performance... - Rescue angioplasty or repeat fibrinolysis after failed fibrinolytic therapy for ST-segment myocardial infarction: a meta-analysis of randomized trialsHarindra C Wijeysundera
Division of Cardiology, Schulich Heart Centre and Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
J Am Coll Cardiol 49:422-30. 2007.... - Delayed time to defibrillation after in-hospital cardiac arrestPaul S Chan
Saint Luke s Mid America Heart Institute, Kansas City, MO 64111, USA
N Engl J Med 358:9-17. 2008..However, empirical data on the prevalence of delayed defibrillation in the United States and its effect on survival are limited... - Certificate of need regulation and cardiac catheterization appropriateness after acute myocardial infarctionJoseph S Ross
Department of Geriatrics and Adult Development, Mount Sinai School of Medicine, One Gustave L Levy Pl, Box 1070, New York, NY 10029, USA
Circulation 115:1012-9. 2007..Our objective was to examine whether rates of appropriate cardiac catheterization after admission for acute myocardial infarction varied between states with and without CON regulation of cardiac catheterization... - Strategies for reducing the door-to-balloon time in acute myocardial infarctionElizabeth H Bradley
Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, USA
N Engl J Med 355:2308-20. 2006..CONCLUSIONS: Several specific hospital strategies are associated with a significant reduction in the door-to-balloon time in the management of myocardial infarction with ST-segment elevation... - Impact of delay in door-to-needle time on mortality in patients with ST-segment elevation myocardial infarctionRobert L McNamara
Department of Medicine, Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, CT, USA
Am J Cardiol 100:1227-32. 2007..87, respectively; p for trend <0.001). In conclusion, timely administration of fibrinolytic therapy continues to significantly impact on mortality in the modern era, particularly in patients presenting early after symptom onset... - Delay in presentation and reperfusion therapy in ST-elevation myocardial infarctionHenry H Ting
Division of Cardiovascular Diseases and Mayo Clinic College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
Am J Med 121:316-23. 2008..We studied the relationship between longer delays from symptom onset to hospital presentation and the use of any reperfusion therapy, door-to-balloon time, and door-to-drug time... - Hospital delays in reperfusion for ST-elevation myocardial infarction: implications when selecting a reperfusion strategyDuane S Pinto
TIMI Study Group and the Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, 185 Pilgrim Rd, Boston, MA 02115, USA
Circulation 114:2019-25. 2006..As indicated in the American College of Cardiology/American Heart Association guidelines, both the hospital-based PPCI-related delay (DB-DN time) and patient characteristics should be considered when a reperfusion strategy is selected... - Do specialty cardiac hospitals have greater adherence to acute myocardial infarction and heart failure process measures? An empirical assessment using Medicare quality measures: quality of care in cardiac specialty hospitalsIoana Popescu
The Center for Research in Implementation of Innovative Strategies in Practice, Iowa City VA Medical Center, Iowa City, IA, USA
Am Heart J 156:155-60. 2008..Supporters of specialty hospitals claim these facilities provide better patient care; however, empirical data on quality of care in specialty hospitals are limited... - Cardiac Certificate of Need regulations and the availability and use of revascularization servicesVivian Ho
Baker Institute for Public Policy, Rice University, Houston, TX 77005, USA
Am Heart J 154:767-75. 2007..We assessed the association between cardiac CON regulations, availability of revascularization facilities, and revascularization rates... - Summary of evidence regarding hospital strategies to reduce door-to-balloon times for patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary interventionElizabeth H Bradley
Section of Health Policy and Administration, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut, USA
Crit Pathw Cardiol 6:91-7. 2007..In conclusion, although evidence of "what works" is based on observational studies rather than randomized trials, there is evidence on effective interventions to reduce door-to-balloon time... - Use of the electrocardiogram in optimizing reperfusion for ST-elevation myocardial infarction: a new role for an old tool?Christos Kasapis
Eur Heart J 28:2957-9. 2007 - Comparing hospital performance in door-to-balloon time between the Hospital Quality Alliance and the National Cardiovascular Data RegistryBrahmajee K Nallamothu
J Am Coll Cardiol 50:1517-9. 2007 - Keeping apples and oranges separate: reassessing clinical trials that use composite end points as their primary outcomePaul S Chan
J Am Coll Cardiol 48:850; author reply 851-2. 2006 - Admission body temperature and mortality in elderly patients hospitalized for heart failureBrahmajee K Nallamothu
J Am Coll Cardiol 47:2563-4. 2006 - Factors associated with longer time from symptom onset to hospital presentation for patients with ST-elevation myocardial infarctionHenry H Ting
Division of Cardiovascular Diseases and Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
Arch Intern Med 168:959-68. 2008..Previous studies have demonstrated the effects of single factors, such as age, sex, and race, with longer delays from symptom onset to hospital presentation in patients with ST-elevation myocardial infarction... - Prognostic utility of microvolt T-wave alternans in risk stratification of patients with ischemic cardiomyopathyTheodore Chow
The Lindner Clinical Trial Center at the Christ Hospital and the Ohio Heart and Vascular Center, Cincinnati, Ohio, USA
J Am Coll Cardiol 47:1820-7. 2006..08 [1.18 to 3.66]; p = 0.01). CONCLUSIONS: Microvolt T-wave alternans is a strong and independent predictor of all-cause and arrhythmic mortality in patients with ischemic cardiomyopathy... - Implementation and integration of prehospital ECGs into systems of care for acute coronary syndrome: a scientific statement from the American Heart Association Interdisciplinary Council on Quality of Care and Outcomes Research, Emergency Cardiovascular CaHenry H Ting
Circulation 118:1066-79. 2008 - Development of systems of care for ST-elevation myocardial infarction patients: gaps, barriers, and implicationsBrahmajee K Nallamothu
Circulation 116:e68-72. 2007
Research Grants
- Impact of Specialty Hospitals on Procedure UtilizationBrahmajee Nallamothu; Fiscal Year: 2005....