Terunaga Nakagawa

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc The biochemistry, ultrastructure, and subunit assembly mechanism of AMPA receptors
    Terunaga Nakagawa
    Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Mol Neurobiol 42:161-84. 2010
  2. ncbi Three-dimensional structure of an AMPA receptor without associated stargazin/TARP proteins
    Terunaga Nakagawa
    The Picower Center for Learning and Memory, RIKEN MIT Neuroscience Research Center, Howard Hughes Medical Institute, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA
    Biol Chem 387:179-87. 2006
  3. pmc The macromolecular architecture of extracellular domain of alphaNRXN1: domain organization, flexibility, and insights into trans-synaptic disposition
    Davide Comoletti
    Department of Pharmacology, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093, USA
    Structure 18:1044-53. 2010
  4. pmc Contribution of the global subunit structure and stargazin on the maturation of AMPA receptors
    Natalie F Shanks
    Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093, USA
    J Neurosci 30:2728-40. 2010
  5. pmc Differences in AMPA and kainate receptor interactomes facilitate identification of AMPA receptor auxiliary subunit GSG1L
    Natalie F Shanks
    Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA
    Cell Rep 1:590-8. 2012
  6. pmc Separation of domain contacts is required for heterotetrameric assembly of functional NMDA receptors
    Anthony N Farina
    Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093, USA
    J Neurosci 31:3565-79. 2011
  7. ncbi Molecular architecture of botulinum neurotoxin E revealed by single particle electron microscopy
    Audrey Fischer
    Section of Neurobiology, Division of Biological Sciences, University of California San Diego, La Jolla, CA 92093 0366, USA
    J Biol Chem 283:3997-4003. 2008

Collaborators

Detail Information

Publications7

  1. pmc The biochemistry, ultrastructure, and subunit assembly mechanism of AMPA receptors
    Terunaga Nakagawa
    Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Mol Neurobiol 42:161-84. 2010
    ..Moreover, we are getting closer to understanding the precise mechanisms of AMPA-R-mediated synaptic plasticity...
  2. ncbi Three-dimensional structure of an AMPA receptor without associated stargazin/TARP proteins
    Terunaga Nakagawa
    The Picower Center for Learning and Memory, RIKEN MIT Neuroscience Research Center, Howard Hughes Medical Institute, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA
    Biol Chem 387:179-87. 2006
    ..In the absence of stargazin/TARP proteins, the density representing the transmembrane region of the AMPA-R particles is substantially smaller, corroborating our previous analysis that was based solely on projection images...
  3. pmc The macromolecular architecture of extracellular domain of alphaNRXN1: domain organization, flexibility, and insights into trans-synaptic disposition
    Davide Comoletti
    Department of Pharmacology, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093, USA
    Structure 18:1044-53. 2010
    ..We thus provide the first structural insights into the architecture of the extracellular region of neurexin-1alpha, show how the protein may fit in the synaptic cleft, and how partnering proteins could bind simultaneously...
  4. pmc Contribution of the global subunit structure and stargazin on the maturation of AMPA receptors
    Natalie F Shanks
    Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093, USA
    J Neurosci 30:2728-40. 2010
    ..The contribution of stargazin on the subunit assembly of AMPA-R was examined. Our data suggest that stargazin affects AMPA-R trafficking at a later stage of receptor maturation...
  5. pmc Differences in AMPA and kainate receptor interactomes facilitate identification of AMPA receptor auxiliary subunit GSG1L
    Natalie F Shanks
    Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA
    Cell Rep 1:590-8. 2012
    ..GSG1L extends the functional variety of AMPA-R complexes, and further investigation of other candidates may reveal additional complexity of ionotropic glutamate receptor function...
  6. pmc Separation of domain contacts is required for heterotetrameric assembly of functional NMDA receptors
    Anthony N Farina
    Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093, USA
    J Neurosci 31:3565-79. 2011
    ....
  7. ncbi Molecular architecture of botulinum neurotoxin E revealed by single particle electron microscopy
    Audrey Fischer
    Section of Neurobiology, Division of Biological Sciences, University of California San Diego, La Jolla, CA 92093 0366, USA
    J Biol Chem 283:3997-4003. 2008
    ..We postulate that the unique architecture of functionally conserved modules underlies the distinguishing attributes of BoNT/E and contributes to differences with BoNT/A...

Research Grants2