TIMOTHY NAGY

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. ncbi request reprint Effects of gender, ethnicity, body composition, and fat distribution on serum leptin concentrations in children
    T R Nagy
    Department of Nutrition Sciences, University of Alabama at Birmingham 35294, USA
    J Clin Endocrinol Metab 82:2148-52. 1997
  2. ncbi request reprint Effect of group vs. single housing on phenotypic variance in C57BL/6J mice
    Tim R Nagy
    Department of Nutrition Sciences, University of Alabama at Birmingham, 35294 3360, USA
    Obes Res 10:412-5. 2002
  3. ncbi request reprint Precision and accuracy of dual-energy X-ray absorptiometry for determining in vivo body composition of mice
    T R Nagy
    Department of Nutrition Sciences, University of Alabama at Birmingham, USA
    Obes Res 8:392-8. 2000
  4. ncbi request reprint Serum leptin and energy expenditure in children
    T R Nagy
    Department of Nutrition Sciences, School of Health Related Professions, University of Alabama at Birmingham 35294, USA
    J Clin Endocrinol Metab 82:4149-53. 1997
  5. ncbi request reprint Role of UCP2 and UCP3 in nutrition and obesity
    Tim R Nagy
    Department of Nutrition Sciences and the Clinical Nutrition Research Center, University of Alabama at Birmingham, Birmingham, Alabama 35294 3360, USA
    Nutrition 20:139-44. 2004
  6. doi request reprint Effect of exercise and calorie restriction on biomarkers of aging in mice
    Derek M Huffman
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL, USA
    Am J Physiol Regul Integr Comp Physiol 294:R1618-27. 2008
  7. ncbi request reprint Evaluation of liver fatty acid oxidation in the leptin-deficient obese mouse
    Amy E Brix
    Departments of Genomics and Pathobiology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Mol Genet Metab 75:219-26. 2002
  8. ncbi request reprint Effects of energy expenditure and Ucp1 on photoperiod-induced weight gain in collard lemmings
    Charles Stephenson Powell
    Department of Nutrition Sciences, The University of Alabama at Birmingham, 35294 3360, USA
    Obes Res 10:541-50. 2002
  9. ncbi request reprint Cancer progression in the transgenic adenocarcinoma of mouse prostate mouse is related to energy balance, body mass, and body composition, but not food intake
    Derek M Huffman
    Department of Nutrition Sciences, University of Alabama at Birmingham, 1675 University Boulevard, Birmingham, AL 35294, USA
    Cancer Res 67:417-24. 2007
  10. pmc Risperidone alters food intake, core body temperature, and locomotor activity in mice
    Mark B Cope
    Department of Nutrition Sciences, University of Alabama at Birmingham, United States
    Physiol Behav 96:457-63. 2009

Research Grants

Collaborators

Detail Information

Publications27

  1. ncbi request reprint Effects of gender, ethnicity, body composition, and fat distribution on serum leptin concentrations in children
    T R Nagy
    Department of Nutrition Sciences, University of Alabama at Birmingham 35294, USA
    J Clin Endocrinol Metab 82:2148-52. 1997
    ..Serum leptin concentrations were not influenced by ethnicity. Thus, when comparing group differences in serum leptin concentrations, it is necessary to adequately control for group differences in body composition and fat distribution...
  2. ncbi request reprint Effect of group vs. single housing on phenotypic variance in C57BL/6J mice
    Tim R Nagy
    Department of Nutrition Sciences, University of Alabama at Birmingham, 35294 3360, USA
    Obes Res 10:412-5. 2002
    ..To determine if group housing affects the variance of body composition parameters in a highly inbred mouse strain...
  3. ncbi request reprint Precision and accuracy of dual-energy X-ray absorptiometry for determining in vivo body composition of mice
    T R Nagy
    Department of Nutrition Sciences, University of Alabama at Birmingham, USA
    Obes Res 8:392-8. 2000
    ..To evaluate the precision and accuracy of dual-energy X-ray absorptiometry (DXA) for the measurement of total-bone mineral density (TBMD), total-body bone mineral (TBBM), fat mass (FM), and bone-free lean tissue mass (LTM) in mice...
  4. ncbi request reprint Serum leptin and energy expenditure in children
    T R Nagy
    Department of Nutrition Sciences, School of Health Related Professions, University of Alabama at Birmingham 35294, USA
    J Clin Endocrinol Metab 82:4149-53. 1997
    ..Thus, our data do not support the hypothesis that the serum leptin concentration (independent of fat mass) is related to measures of energy expenditure in children...
  5. ncbi request reprint Role of UCP2 and UCP3 in nutrition and obesity
    Tim R Nagy
    Department of Nutrition Sciences and the Clinical Nutrition Research Center, University of Alabama at Birmingham, Birmingham, Alabama 35294 3360, USA
    Nutrition 20:139-44. 2004
  6. doi request reprint Effect of exercise and calorie restriction on biomarkers of aging in mice
    Derek M Huffman
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL, USA
    Am J Physiol Regul Integr Comp Physiol 294:R1618-27. 2008
    ....
  7. ncbi request reprint Evaluation of liver fatty acid oxidation in the leptin-deficient obese mouse
    Amy E Brix
    Departments of Genomics and Pathobiology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Mol Genet Metab 75:219-26. 2002
    ..In summary, despite obese mice having an excess of fat available for mitochondrial beta-oxidation in liver, overall energy balance appeared to dictate that the net liver FAO remained at control levels...
  8. ncbi request reprint Effects of energy expenditure and Ucp1 on photoperiod-induced weight gain in collard lemmings
    Charles Stephenson Powell
    Department of Nutrition Sciences, The University of Alabama at Birmingham, 35294 3360, USA
    Obes Res 10:541-50. 2002
    ..To determine the role of total energy expenditure (TEE) and its components in the ability of collared lemmings to increase weight in response to a decrease in photoperiod...
  9. ncbi request reprint Cancer progression in the transgenic adenocarcinoma of mouse prostate mouse is related to energy balance, body mass, and body composition, but not food intake
    Derek M Huffman
    Department of Nutrition Sciences, University of Alabama at Birmingham, 1675 University Boulevard, Birmingham, AL 35294, USA
    Cancer Res 67:417-24. 2007
    ....
  10. pmc Risperidone alters food intake, core body temperature, and locomotor activity in mice
    Mark B Cope
    Department of Nutrition Sciences, University of Alabama at Birmingham, United States
    Physiol Behav 96:457-63. 2009
    ....
  11. ncbi request reprint SIRT1 is significantly elevated in mouse and human prostate cancer
    Derek M Huffman
    Division of Physiology and Metabolism, Department of Nutrition Sciences, University of Alabama at Birmingham, 1670 University Boulevard, Birmingham, AL 35294, USA
    Cancer Res 67:6612-8. 2007
    ..Because SIRT1 may function as a tumor promoter, these results suggest that SIRT1 should be considered as a potential therapeutic target for prostate cancer...
  12. pmc The effect of mannan oligosaccharide supplementation on body weight gain and fat accrual in C57Bl/6J mice
    Daniel L Smith
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL, USA
    Obesity (Silver Spring) 18:995-9. 2010
    ..247 g; P = 0.57). Contrary to previous research, MOS supplementation had no discernable effect on body weight gain or composition during this 12-week study, challenging the potential use of MOS as a CRM or body composition enhancer...
  13. ncbi request reprint Effect of dairy supplementation on body composition and insulin resistance in mice
    Maria S Johnson
    Department of Nutrition Sciences, University of Alabama at Birmingham, Alabama, USA
    Nutrition 23:836-43. 2007
    ..This study examined whether yogurt supplementation attenuated the weight gain and insulin resistance in mice fed a moderate-fat diet...
  14. pmc Calorie restriction: what recent results suggest for the future of ageing research
    Daniel L Smith
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Eur J Clin Invest 40:440-50. 2010
    ..Thus, the search for substances that can reproduce the beneficial physiologic responses of CR without a requisite calorie intake reduction, termed CR mimetics (CRMs), has gained momentum...
  15. ncbi request reprint Body composition in a seasonal model of obesity: longitudinal measures and validation of DXA
    Heather L Hunter
    Department of Biology, University of Alabama at Birmingham, Birmingham, Alabama 35294 3360, USA
    Obes Res 10:1180-7. 2002
    ..The objective of this study was to measure longitudinal changes in body composition in animals undergoing photoperiod-induced weight gain and loss using DXA...
  16. ncbi request reprint Estradiol may limit lipid oxidation via Cpt 1 expression and hormonal mechanisms
    Barbara A Gower
    Department of Nutrition Sciences and Physiology, University of Alabama at Birmingham and the Clinical Nutrition Research Center, Birmingham, Alabama 35294 3360, USA
    Obes Res 10:167-72. 2002
    ..Evidence indicates that estrogen depresses hepatic lipid oxidation. We tested the hypothesis that estradiol (E(2)) treatment depresses transcription of carnitine palmitoyltransferase-1 (Cpt 1) mRNA and increases adiposity...
  17. pmc Mild calorie restriction induces fat accumulation in female C57BL/6J mice
    Xingsheng Li
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Obesity (Silver Spring) 18:456-62. 2010
    ..The increase in fat mass and decrease in lean mass may be a stress response to the uncertainty of food availability...
  18. doi request reprint High-fat diet exacerbates inflammation and cell survival signals in the skin of ultraviolet B-irradiated C57BL/6 mice
    Syed M Meeran
    Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Toxicol Appl Pharmacol 241:303-10. 2009
    ....
  19. pmc The role of European genetic admixture in the etiology of the insulin resistance syndrome in children: are the effects mediated by fat accumulation?
    Krista Casazza
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294 3360, USA
    J Pediatr 157:50-56.e1. 2010
    ..To evaluate the contribution of European genetic admixture (EUADM) to insulin resistance syndrome (IRS) in a multiethnic sample of children age 7-12 years, and to explore whether body fat affects this relationship...
  20. ncbi request reprint Ucp3 expression during weight gain and loss, cold exposure, and fasting in the collared lemming
    Matthew L Blaylock
    Webb Building 419, 1530 Third Avenue South, Birmingham, AL 35294 3360, USA
    Obes Res 12:1690-7. 2004
    ....
  21. pmc Disruption of intraflagellar transport in adult mice leads to obesity and slow-onset cystic kidney disease
    James R Davenport
    Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Curr Biol 17:1586-94. 2007
    ..These data establish that neuronal cilia function in a pathway regulating satiety responses...
  22. ncbi request reprint Osteogenic differentiation of recombinant adeno-associated virus 2-transduced murine mesenchymal stem cells and development of an immunocompetent mouse model for ex vivo osteoporosis gene therapy
    Sanjay Kumar
    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Hum Gene Ther 15:1197-206. 2004
    ..Thus, in the present study, we determined the influence of these factors and developed an immunocompetent mouse model of osteoporosis with degenerative bone loss as in the human pathology...
  23. ncbi request reprint Osteoclast apoptosis: the role of Fas in vivo and in vitro
    Xiaojun Wu
    Department of Pathology, Nutrition Sciences, University of Alabama at Birmingham, Alabama 35294 0007, USA
    Endocrinology 144:5545-55. 2003
    ..Taken together, these data demonstrate that the Fas/Fas ligand system is important in the regulation of bone turnover and may represent a critical link between the immune system and bone remodeling in development and in various diseases...
  24. ncbi request reprint Weight change affects serum leptin and corticosterone in the collared lemming
    Maria S Johnson
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Gen Comp Endocrinol 136:30-6. 2004
    ..Neither relative leptin levels, nor corticosterone levels changed significantly with weight gain. Our results indicate that corticosterone and leptin are associated more with seasonal weight loss than weight gain in lemmings...
  25. ncbi request reprint HIV protease inhibitor ritonavir induces lipoatrophy in male mice
    Eric S Goetzman
    Department of Genetics, University of Alabama at Birmingham, Alabama 35294, USA
    AIDS Res Hum Retroviruses 19:1141-50. 2003
    ..Thus, the effects of ritonavir on serum triglycerides and body composition may be due, at least in part, to an inhibition of PPAR function...
  26. ncbi request reprint Molecules mimicking Smad1 interacting with Hox stimulate bone formation
    Zhiyong Liu
    Department of Pathology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama 35294, USA
    J Biol Chem 279:11313-9. 2004
    ....
  27. pmc Dietary strontium increases bone mineral density in intact zebrafish (Danio rerio): a potential model system for bone research
    Anthony J Siccardi
    Department of Biology, University of Alabama at Birmingham, Alabama 35295 1170, USA
    Zebrafish 7:267-73. 2010
    ..e., rat, mouse, and monkey) that received supplements of strontium compounds and zebrafish should be viewed as an increasingly valuable bone model...

Research Grants14

  1. Body fat, dietary restriction, and cancer prevention
    TIMOTHY NAGY; Fiscal Year: 2004
    ..This study will provide evidence for the hypothesis that body fat is the pathway through which CR exerts its cancer protective effects in rodent tumor models. ..
  2. REGULATION OF ENERGY PARTITIONING DURING WEIGHT CHANGE
    TIMOTHY NAGY; Fiscal Year: 2002
    ..The basic scientific information gained from this model should be useful for understanding the role of metabolic perturbations in the etiology of human obesity. ..
  3. Antipsychotic drug-induced weight gain
    TIMOTHY NAGY; Fiscal Year: 2009
    ..abstract_text> ..