James B Nachman
Affiliation: University of Chicago
- Clinical characteristics, biologic features and outcome for young adult patients with acute lymphoblastic leukaemiaJames Nachman
University of Chicago Comer Children s Hospital, MC 4060, 5841 South Maryland Avenue, Chicago, IL 60637, USA
Br J Haematol 130:166-73. 2005..In multiple studies, there is a consistent, large event-free survival and survival advantage for young adult patients treated on paediatric versus adult protocols...
- Randomized comparison of low-dose involved-field radiotherapy and no radiotherapy for children with Hodgkin's disease who achieve a complete response to chemotherapyJames B Nachman
Section of Pediatric Hematology Oncology, University of Chicago, Chicago, IL, USA
J Clin Oncol 20:3765-71. 2002....
- My aching bones: skeletal complications of acute lymphoblastic leukemiaJames B Nachman
Department of Pediatric Hematology Oncology, University of Chicago, Chicago, Illinois 60637, USA
Pediatr Blood Cancer 46:1. 2006
- Young adults with acute lymphoblastic leukemia have an excellent outcome with chemotherapy alone and benefit from intensive postinduction treatment: a report from the children's oncology groupJames B Nachman
University of Chicago Children s Hospital, MC 4060, Chicago, IL 60637, USA
J Clin Oncol 27:5189-94. 2009..We examined outcome for young adults with ALL enrolled onto the Children's Cancer Group (CCG) 1961 study between 1996 and 2002...
- The courage to changeJames Nachman
Section of Pediatric Hematology Oncology and Stem Cell Transplantation, University of Chicago, Chicago, IL, USA
Leuk Lymphoma 49:1026-7. 2008
- What determines the outcomes for adolescents and young adults with acute lymphoblastic leukemia treated on cooperative group protocols? A comparison of Children's Cancer Group and Cancer and Leukemia Group B studiesWendy Stock
Section of Hematology Oncology, Department of Medicine, University of Chicago and University of Chicago Cancer Research Center, IL 60637, USA
Blood 112:1646-54. 2008..Based on these observations, a prospective study for AYAs with ALL using the more successful approach of the CCG has been initiated...
- Outcome of treatment in children with hypodiploid acute lymphoblastic leukemiaJames B Nachman
The University of Chicago Comer Children s Hospital, IL 60637, USA
Blood 110:1112-5. 2007..Children and adolescents with ALL and hypodiploidy with fewer than 44 chromosomes have a poor outcome despite contemporary therapy...
- The optimal use of steroids in paediatric acute lymphoblastic leukaemia: no easy answersJennifer L McNeer
Section of Paediatric Haematology Oncology, University of Chicago Comer Children s Hospital, Chicago, IL, USA
Br J Haematol 149:638-52. 2010..This review will summarize the current available data on steroid use in paediatric ALL, highlighting outcomes as well as major toxicities...
- Early postinduction intensification therapy improves survival for children and adolescents with high-risk acute lymphoblastic leukemia: a report from the Children's Oncology GroupNita L Seibel
Hematology Oncology, Children s National Medical Center and George Washington University School of Medicine and Public Health, 111 Michigan Avenue NW, Washington, DC 20010, USA
Blood 111:2548-55. 2008..Longer duration PII provided no benefit. Stronger intensity but not prolonged duration PII improved outcome for patients with higher-risk ALL. This study is registered at http://clinicaltrials.gov as NCT00002812...
- Abnormalities of chromosome bands 15q13-15 in childhood acute lymphoblastic leukemiaNyla A Heerema
The Ohio State University Medical Center, Department of Pathology, Columbus, Ohio, USA
Cancer 94:1102-10. 2002..To the authors' knowledge, the clinical significance of these breakpoints in childhood acute lymphoblastic leukemia (ALL) has not been previously investigated...