Research Topics
| G J MyersSummaryAffiliation: University of Rochester Country: USA Publications
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Publications
Is susceptibility to prenatal methylmercury exposure from fish consumption non-homogeneous? Tree-structured analysis for the Seychelles Child Development StudyLi Shan Huang
Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Neurotoxicology 28:1237-44. 2007..The regression tree results support previous analyses of outcomes in this cohort. However, this analysis raises the intriguing possibility that an effect may be non-homogeneous among children with different backgrounds and IQ levels...
Postnatal exposure to methyl mercury from fish consumption: a review and new data from the Seychelles Child Development StudyGary J Myers
University of Rochester School of Medicine and Dentistry, Department of Neurology, Rochester, NY, United States
Neurotoxicology 30:338-49. 2009....
Does methylmercury have a role in causing developmental disabilities in children?G J Myers
Department of Neurology, and Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
Environ Health Perspect 108:413-20. 2000..This paper reviews the data presently available associating MeHg exposure with development and poses some of the unanswered questions in this field...
Maternal fish consumption benefits children's developmentGary J Myers
Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, USA
Lancet 369:537-8. 2007
Prenatal methylmercury exposure from ocean fish consumption in the Seychelles child development studyGary J Myers
Department of Neurology, National Institute for Child Health and Development, National Institutes of Health, Department of Health and Human Services, Bethesda, USA
Lancet 361:1686-92. 2003..The most common form of prenatal exposure is maternal fish consumption, but whether such exposure harms the fetus is unknown. We aimed to identify adverse neurodevelopmental effects in a fish-consuming population...
Nutrient and methyl mercury exposure from consuming fishGary J Myers
Department of Neurology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
J Nutr 137:2805-8. 2007..Preliminary findings from this study suggest that the beneficial influence of nutrients from fish may counter any adverse effects of MeHg on the developing nervous system...
Association between methylmercury exposure from fish consumption and child development at five and a half years of age in the Seychelles Child Development Study: an evaluation of nonlinear relationshipsC D Axtell
Department of Biostatistics, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
Environ Res 84:71-80. 2000..Further nonlinear modeling of these data may be appropriate, but there is also the risk of fitting complex models without a clear biological rationale...
Effects of prenatal and postnatal methylmercury exposure from fish consumption on neurodevelopment: outcomes at 66 months of age in the Seychelles Child Development StudyP W Davidson
University of Rochester School of Medicine and Dentistry, NY 14642, USA
JAMA 280:701-7. 1998..Human neurodevelopmental consequences of exposure to methyl-mercury (MeHg) from eating fish remain a question of public health concern...
Semiparametric modeling of age at achieving developmental milestones after prenatal exposure to methylmercury in the Seychelles child development studyC D Axtell
Department of Biostatistics, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642 USA
Environ Health Perspect 106:559-64. 1998..There was no evidence for any association between prenatal exposure and age at talking...
Fish consumption, mercury exposure, and their associations with scholastic achievement in the Seychelles Child Development StudyPhilip W Davidson
University of Rochester, School of Medicine and Dentistry, Department of Pediatrics, Rochester, NY 14642, USA
Neurotoxicology 31:439-47. 2010..The adverse association of educational measures with postnatal exposure in males is intriguing, but will need to be confirmed by further studies examining factors that influence scholastic achievement...
Prenatal methylmercury exposure and children: neurologic, developmental, and behavioral researchG J Myers
Department of Neurology, University of Rochester School of Medicine and Dentistry, New York 14642, USA
Environ Health Perspect 106:841-7. 1998..Current evidence does not support the hypothesis that consumption of such fish during pregnancy places the fetus at increased neurodevelopmental risk...
Interpreting epidemiological evidence in the presence of multiple endpoints: an alternative analytic approach using the 9-year follow-up of the Seychelles child development studyEdwin van Wijngaarden
Department of Community and Preventive Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, 14642, USA
Int Arch Occup Environ Health 82:1031-41. 2009..These studies evaluate a large number of developmental tests. We propose an alternative analysis strategy that reduces the number of comparisons tested in these studies...
Neurodevelopmental effects of maternal nutritional status and exposure to methylmercury from eating fish during pregnancyPhilip W Davidson
University of Rochester School of Medicine and Dentistry, Box 671, URMC, 601 Elmwood Avenue, Rochester, NY 14642, USA
Neurotoxicology 29:767-75. 2008..These findings suggest a possible confounding role of maternal nutrition in studies examining associations between prenatal MeHg exposures and developmental outcomes in children...
Association between prenatal exposure to methylmercury and visuospatial ability at 10.7 years in the seychelles child development studyPhilip W Davidson
University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Neurotoxicology 29:453-9. 2008..04), but not when the single outlier was removed (p=0.07). In a population whose exposure to MeHg is from fish consumption, we continue to find no consistent adverse association between MeHg and visual motor coordination...
Does prenatal methylmercury exposure from fish consumption affect blood pressure in childhood?Sally W Thurston
Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, United States
Neurotoxicology 28:924-30. 2007..We examined this relationship in the Seychelles Islands to determine if it was present in a society exposed primarily to MeHg from consuming ocean fish...
Heptavalent pneumococcal conjugate vaccine immunogenicity in very-low-birth-weight, premature infantsCARL T D'ANGIO
University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
Pediatr Infect Dis J 29:600-6. 2010..The heptavalent pneumococcal CRM197 conjugate vaccine (PCV-7) has been incompletely studied in very-low-birth-weight (< or =1500 g) infants...
Methylmercury and neurodevelopment: longitudinal analysis of the Seychelles child development cohortPhilip W Davidson
The Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, New York, 14642, USA
Neurotoxicol Teratol 28:529-35. 2006..These findings suggest that the associations observed between MeHg and developmental outcomes may vary with developmental stage...
Benchmark concentrations for methyl mercury obtained from the 9-year follow-up of the Seychelles Child Development StudyEdwin van Wijngaarden
Department of Community and Preventive Medicine, 601 Elmwood Avenue, Box 644, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Neurotoxicology 27:702-9. 2006..These estimates are somewhat lower than those obtained after 66 months of follow-up. The Seychelles Child Development Study continues to provide a firm scientific basis for the derivation of safe levels of MeHg consumption...
Development and validation of a test battery to assess subtle neurodevelopmental differences in childrenPhilip W Davidson
University of Rochester School of Medicine, Rochester, NY, USA
Neurotoxicology 27:951-69. 2006..Further studies are needed to confirm the capability of the RTB to detect subtle changes associated with neurotoxic exposures...
Longitudinal, 15-year follow-up of children born at less than 29 weeks' gestation after introduction of surfactant therapy into a region: neurologic, cognitive, and educational outcomesCARL T D'ANGIO
Department of Pediatrics, Strong Children s Research Center, Golisano Children s Hospital at Strong, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
Pediatrics 110:1094-102. 2002..To measure the primary and secondary school-age neurologic, cognitive, and educational outcomes in a cohort of extremely premature infants born after the introduction of exogenous surfactant therapy in a circumscribed region...
Using measurement error models to assess effects of prenatal and postnatal methylmercury exposure in the Seychelles Child Development StudyLi Shan Huang
Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Box 630, Rochester, NY 14642, USA
Environ Res 93:115-22. 2003..Our reanalysis indicated that adjustment for measurement errors in explanatory variables had no appreciable effect on the original results...
Prenatal methyl mercury exposure from fish consumption and child development: a review of evidence and perspectives from the Seychelles Child Development StudyPhilip W Davidson
University of Rochester School of Medicine and Dentistry, USA
Neurotoxicology 27:1106-9. 2006..This suggests that the association between prenatal exposure and child development may be more complex than originally believed. This paper reviews the SCDS main cohort study results and presents our current interpretations...
Pressure-regulated volume control ventilation vs synchronized intermittent mandatory ventilation for very low-birth-weight infants: a randomized controlled trialCARL T D'ANGIO
Strong Children s Research Center, University of Rochester, Rochester, NY 14642, USA
Arch Pediatr Adolesc Med 159:868-75. 2005....
Exploring nonlinear association between prenatal methylmercury exposure from fish consumption and child development: evaluation of the Seychelles Child Development Study nine-year data using semiparametric additive modelsLi Shan Huang
Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Environ Res 97:100-8. 2005..We conclude that this reanalysis supports the primary linear analysis, showing little evidence for a prenatal adverse effect...
Mercury exposure and child development outcomesPhilip W Davidson
Strong Center for Developmental Disabilities, Golisano Children s Hospital at Strong, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
Pediatrics 113:1023-9. 2004..Our intent is to focus the debate about mercury on 1) additional research that should be sought and 2) defining the principal issues that public policy makers face...
Prenatal exposure to methylmercury and child development: influence of social factorsPhilip W Davidson
Strong Center for Developmental Disabilities, Department of Pediatrics, Box 671, School of Medicine and Dentistry, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642, USA
Neurotoxicol Teratol 26:553-9. 2004..We performed a similar analysis of the 66-month evaluations to determine if the modifying influences of social and environmental factors were consistent with those previously observed...
Varying coefficient function models to explore interactions between maternal nutritional status and prenatal methylmercury toxicity in the Seychelles Child Development Nutrition StudyMiranda L Lynch
Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Environ Res 111:75-80. 2011..The results encourage more emphasis on a holistic view of the risks and benefits of fish consumption as it relates to infant development...
The toxicology of mercury--current exposures and clinical manifestationsThomas W Clarkson
Department of Environmental Medicine, University of Rochester School of Medicine, Rochester, NY 14642, USA
N Engl J Med 349:1731-7. 2003
Evaluation of techniques for assessing neurobehavioral development in childrenP W Davidson
Department of Pediatrics, University of Rochester School of Medicine and Dentistry, NY 14642, USA
Neurotoxicology 21:957-72. 2000..Our findings suggest a number of tests and procedures with the potential for inclusion in test batteries aimed at the exploration of adverse neurodevelopmental effects...
The biological monitoring of prenatal exposure to methylmercuryE Cernichiari
Department of Environmental Medicine, University of Rochester School of Medicine, Rochester, New York, United States
Neurotoxicology 28:1015-22. 2007....
Neurodevelopmental outcomes of premature infants with severe respiratory failure enrolled in a randomized controlled trial of inhaled nitric oxideSusan R Hintz
NICHD Neonatal Research Network
J Pediatr 151:16-22, 22.e1-3. 2007....
Homocysteine concentration, related B vitamins, and betaine in pregnant women recruited to the Seychelles Child Development StudyJulie Mw Wallace
Northern Ireland Centre for Food and Health, School of Biomedical Sciences, University of Ulster, Coleraine, United Kingdom
Am J Clin Nutr 87:391-7. 2008..Both folate and betaine are important predictors of total homocysteine (tHcy) during pregnancy. However, studies to date have only been undertaken in populations with Western dietary patterns...
