Amanda J Myers

Summary

Affiliation: University of Miami
Country: USA

Publications

  1. doi request reprint AD gene 3-D: moving past single layer genetic information to map novel loci involved in Alzheimer's disease
    Amanda J Myers
    Laboratory of Functional Neurogenomics, Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    J Alzheimers Dis 33:S15-22. 2013
  2. doi request reprint The age of the "ome": genome, transcriptome and proteome data set collection and analysis
    Amanda J Myers
    Laboratory of Functional Neurogenomics, University of Miami, Miller School of Medicine, Department of Psychiatry and Behavioral Sciences, Division of Neuroscience, Miami, FL 33136, USA
    Brain Res Bull 88:294-301. 2012
  3. ncbi request reprint A survey of genetic human cortical gene expression
    Amanda J Myers
    Laboratory of Neurogenetics, National Institute on Aging, Porter Neuroscience Building, National Institutes of Health Main Campus, Bethesda, Maryland 20892, USA
    Nat Genet 39:1494-9. 2007
  4. ncbi request reprint The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts
    Amanda J Myers
    Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, 35 Convent Drive, Bethesda, MD 20892 3707, USA
    Neurobiol Dis 25:561-70. 2007
  5. pmc Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
    Adam C Naj
    The John P Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA
    Nat Genet 43:436-41. 2011
  6. ncbi request reprint The structure of the tau haplotype in controls and in progressive supranuclear palsy
    Alan M Pittman
    Reta Lila Weston Institute of Neurological Studies, University College London, UK
    Hum Mol Genet 13:1267-74. 2004
  7. ncbi request reprint A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease
    Keith D Coon
    Neurogenomics Division, Translational Genomics Research Institute, Phoenix, Ariz 85004, USA
    J Clin Psychiatry 68:613-8. 2007
  8. pmc GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers
    Eric M Reiman
    Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, 85004, USA
    Neuron 54:713-20. 2007

Detail Information

Publications8

  1. doi request reprint AD gene 3-D: moving past single layer genetic information to map novel loci involved in Alzheimer's disease
    Amanda J Myers
    Laboratory of Functional Neurogenomics, Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    J Alzheimers Dis 33:S15-22. 2013
    ..The emphasis will be on taking genomics to the next level by applying additional datasets to truly create maps of a 3-dimensional Alzheimer's genome by including the downstream effects of risk variation...
  2. doi request reprint The age of the "ome": genome, transcriptome and proteome data set collection and analysis
    Amanda J Myers
    Laboratory of Functional Neurogenomics, University of Miami, Miller School of Medicine, Department of Psychiatry and Behavioral Sciences, Division of Neuroscience, Miami, FL 33136, USA
    Brain Res Bull 88:294-301. 2012
    ..This article is part of a Special Issue entitled 'Transcriptome'...
  3. ncbi request reprint A survey of genetic human cortical gene expression
    Amanda J Myers
    Laboratory of Neurogenetics, National Institute on Aging, Porter Neuroscience Building, National Institutes of Health Main Campus, Bethesda, Maryland 20892, USA
    Nat Genet 39:1494-9. 2007
    ....
  4. ncbi request reprint The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts
    Amanda J Myers
    Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, 35 Convent Drive, Bethesda, MD 20892 3707, USA
    Neurobiol Dis 25:561-70. 2007
    ..We discuss these findings both in terms of the problems facing the dissection of the etiologies of complex traits and the pathogenesis of the tauopathies...
  5. pmc Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
    Adam C Naj
    The John P Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA
    Nat Genet 43:436-41. 2011
    ..3 × 10(-8), P(J) = 1.9 × 10(-8)), BIN1 (rs7561528; P(M) = 4.0 × 10(-14), P(J) = 5.2 × 10(-14)) and PICALM (rs561655; P(M) = 7.0 × 10(-11), P(J) = 1.0 × 10(-10)), but not at EXOC3L2, to late-onset Alzheimer's disease susceptibility...
  6. ncbi request reprint The structure of the tau haplotype in controls and in progressive supranuclear palsy
    Alan M Pittman
    Reta Lila Weston Institute of Neurological Studies, University College London, UK
    Hum Mol Genet 13:1267-74. 2004
    ..We show that the entire, fully extended H1 haplotype is associated with PSP, which implicates several other genes in addition to MAPT, as candidate pathogenic loci...
  7. ncbi request reprint A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease
    Keith D Coon
    Neurogenomics Division, Translational Genomics Research Institute, Phoenix, Ariz 85004, USA
    J Clin Psychiatry 68:613-8. 2007
    ....
  8. pmc GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers
    Eric M Reiman
    Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, 85004, USA
    Neuron 54:713-20. 2007
    ..Our findings suggest that GAB2 modifies LOAD risk in APOE epsilon4 carriers and influences Alzheimer's neuropathology...

Research Grants2

  1. THE HUMAN BRAINOME:genome, transcriptome and proteome interaction in human cortex
    Amanda Myers; Fiscal Year: 2009
    ..This information will help us to define the downstream significance of DNA risk variation in Alzheimer's disease, which might aid in the discovery of novel biomarkers and therapies for this devastating illness. ..
  2. THE HUMAN BRAINOME:genome, transcriptome and proteome interaction in human cortex
    Amanda J Myers; Fiscal Year: 2010
    ..This information will help us to define the downstream significance of DNA risk variation in Alzheimer's disease, which might aid in the discovery of novel biomarkers and therapies for this devastating illness. ..