Affiliation: University of Rochester
- Fusion estrogen receptor proteins: toward the development of receptor-based agonists and antagonistsM Muyan
Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, NY 14642, USA
Mol Cell Endocrinol 182:249-63. 2001..These results show the utility of fusion receptors as models for generation of receptor-based agonists and antagonists...
- The ligand-mediated nuclear mobility and interaction with estrogen-responsive elements of estrogen receptors are subtype specificMesut Muyan
Department of Biochemistry and Biophysics, University of Rochester Medical School, Rochester, New York 14642, USA
J Mol Endocrinol 49:249-66. 2012..Therefore, while ERs are highly mobile molecules interacting with target sites with fast kinetics, an indication of the hit-and-run model of transcription, they differ mechanistically to modulate transcriptions...
- Toward a transcription therapy for breast cancerMesut Muyan; Fiscal Year: 2010..We anticipate that findings will be critical for the identification of new therapeutic targets, the development of prognostic tools and of a novel "transcription therapy" for breast cancer. ..