Carlene A Muto

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint Control of an outbreak of infection with the hypervirulent Clostridium difficile BI strain in a university hospital using a comprehensive "bundle" approach
    Carlene A Muto
    Division of Hospital Epidemiology and Infection Control, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Clin Infect Dis 45:1266-73. 2007
  2. ncbi request reprint A large outbreak of Clostridium difficile-associated disease with an unexpected proportion of deaths and colectomies at a teaching hospital following increased fluoroquinolone use
    Carlene A Muto
    Division of Hospital Epidemiology and Infection Control, University of Pittsburgh Medical Center, Presbyterian Campus, Pittsburgh, Pennsylvania 15213, USA
    Infect Control Hosp Epidemiol 26:273-80. 2005
  3. pmc High frequency of rifampin resistance identified in an epidemic Clostridium difficile clone from a large teaching hospital
    Scott R Curry
    Department of Medicine, Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Clin Infect Dis 48:425-9. 2009
  4. pmc Perirectal swab surveillance for Clostridium difficile by use of selective broth preamplification and real-time PCR detection of tcdB
    Scott R Curry
    Division of Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
    J Clin Microbiol 49:3788-93. 2011
  5. pmc Multilocus variable-number tandem-repeat analysis for investigation of Clostridium difficile transmission in Hospitals
    Jane W Marsh
    Infectious Diseases Epidemiology Research Unit, University of Pittsburgh School of Medicine and Medical Center, Division of Hospital Epidemiology and Infection Control, 865 Scaife Hall, 3550 Terrace Street, Pittsburgh, PA 15261, USA
    J Clin Microbiol 44:2558-66. 2006
  6. pmc Molecular epidemiology of CTX-M-producing Escherichia coli isolates at a tertiary medical center in western Pennsylvania
    Hanna E Sidjabat
    Division of Infectious Diseases, University of Pittsburgh Medical Center, 3550 Terrace Street, Pittsburgh, PA 15261, USA
    Antimicrob Agents Chemother 53:4733-9. 2009
  7. pmc tcdC genotypes associated with severe TcdC truncation in an epidemic clone and other strains of Clostridium difficile
    Scott R Curry
    Department of Medicine, University of Pittsburgh, School of Medicine, PA 15261, USA
    J Clin Microbiol 45:215-21. 2007
  8. pmc Colistin-resistant, Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae belonging to the international epidemic clone ST258
    Tatiana Bogdanovich
    Division of Infectious Diseases, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Clin Infect Dis 53:373-6. 2011
  9. pmc Screening for Acinetobacter baumannii colonization by use of sponges
    Yohei Doi
    Division of Infectious Diseases, University of Pittsburgh Medical Center, Scaife Hall S829, 3550 Terrace Street, Pittsburgh, PA 15261, USA
    J Clin Microbiol 49:154-8. 2011
  10. doi request reprint Patient-associated risk factors for acquisition of methicillin-resistant Staphylococcus aureus in a tertiary care hospital
    Jo anne M Salangsang
    Division of Infectious Diseases, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Infect Control Hosp Epidemiol 31:1139-47. 2010

Collaborators

Detail Information

Publications26

  1. ncbi request reprint Control of an outbreak of infection with the hypervirulent Clostridium difficile BI strain in a university hospital using a comprehensive "bundle" approach
    Carlene A Muto
    Division of Hospital Epidemiology and Infection Control, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Clin Infect Dis 45:1266-73. 2007
    ..Forty-seven (51%) of 92 HA CD isolates in 2001 were identified as the "epidemic BI strain." A comprehensive CD infection control "bundle" was implemented to control the outbreak of CD infection...
  2. ncbi request reprint A large outbreak of Clostridium difficile-associated disease with an unexpected proportion of deaths and colectomies at a teaching hospital following increased fluoroquinolone use
    Carlene A Muto
    Division of Hospital Epidemiology and Infection Control, University of Pittsburgh Medical Center, Presbyterian Campus, Pittsburgh, Pennsylvania 15213, USA
    Infect Control Hosp Epidemiol 26:273-80. 2005
    ..difficile infections; of these, 26 resulted in colectomy and 18 resulted in death. We conducted an investigation of a large C. difficile outbreak in our hospital to identify risk factors and characterize the outbreak...
  3. pmc High frequency of rifampin resistance identified in an epidemic Clostridium difficile clone from a large teaching hospital
    Scott R Curry
    Department of Medicine, Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Clin Infect Dis 48:425-9. 2009
    ..difficile-associated disease. Rifampin resistance in C. difficile strains has been reported to be uncommon...
  4. pmc Perirectal swab surveillance for Clostridium difficile by use of selective broth preamplification and real-time PCR detection of tcdB
    Scott R Curry
    Division of Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
    J Clin Microbiol 49:3788-93. 2011
    ..6%), and 422/422 (100.0%), respectively. These data demonstrate that selective broth preamplification and real-time PCR of perirectal swab specimens constitute a practical approach to the detection of asymptomatic C. difficile carriage...
  5. pmc Multilocus variable-number tandem-repeat analysis for investigation of Clostridium difficile transmission in Hospitals
    Jane W Marsh
    Infectious Diseases Epidemiology Research Unit, University of Pittsburgh School of Medicine and Medical Center, Division of Hospital Epidemiology and Infection Control, 865 Scaife Hall, 3550 Terrace Street, Pittsburgh, PA 15261, USA
    J Clin Microbiol 44:2558-66. 2006
    ..Thus, MLVA is an objective, portable genotyping method that permits reliable detection of C. difficile outbreaks and can aid epidemiologic investigations of nosocomial transmission...
  6. pmc Molecular epidemiology of CTX-M-producing Escherichia coli isolates at a tertiary medical center in western Pennsylvania
    Hanna E Sidjabat
    Division of Infectious Diseases, University of Pittsburgh Medical Center, 3550 Terrace Street, Pittsburgh, PA 15261, USA
    Antimicrob Agents Chemother 53:4733-9. 2009
    ..Our findings underscore the need to further investigate the epidemiology and virulence of CTX-M-producing E. coli in the United States...
  7. pmc tcdC genotypes associated with severe TcdC truncation in an epidemic clone and other strains of Clostridium difficile
    Scott R Curry
    Department of Medicine, University of Pittsburgh, School of Medicine, PA 15261, USA
    J Clin Microbiol 45:215-21. 2007
    ..Further investigations are required to determine the effect of this and other tcdC genotypes on toxin production and clinical disease...
  8. pmc Colistin-resistant, Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae belonging to the international epidemic clone ST258
    Tatiana Bogdanovich
    Division of Infectious Diseases, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Clin Infect Dis 53:373-6. 2011
    ..These cases likely represented both emergence of resistance and transmission of resistant organism. The colistin-resistant isolates were able to persist in the absence of selective pressure in vitro...
  9. pmc Screening for Acinetobacter baumannii colonization by use of sponges
    Yohei Doi
    Division of Infectious Diseases, University of Pittsburgh Medical Center, Scaife Hall S829, 3550 Terrace Street, Pittsburgh, PA 15261, USA
    J Clin Microbiol 49:154-8. 2011
    ..003). The combined sensitivity for the upper arm and leg with a sponge was 89.1%. The novel screening method using sterile sponges was easy to perform and achieved excellent sensitivity for the detection of A. baumannii colonization...
  10. doi request reprint Patient-associated risk factors for acquisition of methicillin-resistant Staphylococcus aureus in a tertiary care hospital
    Jo anne M Salangsang
    Division of Infectious Diseases, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Infect Control Hosp Epidemiol 31:1139-47. 2010
    ..Determining risk factors for acquisition of methicillin-resistant Staphylococcus aureus (MRSA) in hospitals is important for defining infection-control measures that may lead to fewer hospital-acquired infections...
  11. pmc Genetic basis of multidrug resistance in Acinetobacter baumannii clinical isolates at a tertiary medical center in Pennsylvania
    Jennifer M Adams-Haduch
    Division of Infectious Diseases, University of Pittsburgh Medical Center, S829 Scaife Hall, 3550 Terrace Street, Pittsburgh, PA 15261
    Antimicrob Agents Chemother 52:3837-43. 2008
    ..Fifty-nine percent of the MDR isolates belonged to a single clonal group over the course of the study period, as demonstrated by pulsed-field gel electrophoresis...
  12. doi request reprint Invasive polyarticular septic arthritis caused by nontypeable haemophilus influenzae in a young adult: a case report and literature review
    Jong Hun Kim
    Division of Infectious Diseases, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    J Clin Rheumatol 17:380-2. 2011
    ....
  13. ncbi request reprint SHEA guideline for preventing nosocomial transmission of multidrug-resistant strains of Staphylococcus aureus and enterococcus
    Carlene A Muto
    Division of Hospital Epidemiology and Infection Control, UPMC P, Pittsburgh, Pennsylvania 15213, USA
    Infect Control Hosp Epidemiol 24:362-86. 2003
    ..After 2 more years without improvement, a SHEA task force was appointed to draft this evidence-based guideline on preventing nosocomial transmission of such pathogens, focusing on the two considered most out of control: MRSA and VRE...
  14. ncbi request reprint Asymptomatic Clostridium difficile colonization: is this the tip of another iceberg?
    Carlene A Muto
    Clin Infect Dis 45:999-1000. 2007
  15. ncbi request reprint Another tale of two guidelines
    Carlene A Muto
    Clin Infect Dis 43:796-7;; author reply 797-8. 2006
  16. ncbi request reprint SHEA guideline for preventing nosocomial transmission of multidrug-resistant strains of Staphylococcus aureus and Enterococcus
    Kathleen Ledell
    Infect Control Hosp Epidemiol 24:639-41. 2003
  17. doi request reprint Treatment of Clostridium difficile infection
    Dale N Gerding
    Hines Veterans Affairs Hospital, Hines, IL 60141, USA
    Clin Infect Dis 46:S32-42. 2008
    ..difficile vaccine...
  18. doi request reprint Measures to control and prevent Clostridium difficile infection
    Dale N Gerding
    Hines Veterans Affairs Hospital, Hines, IL 60141, USA
    Clin Infect Dis 46:S43-9. 2008
    ..The efficacy of metronidazole or vancomycin prophylaxis to prevent CDI in patients who are receiving other antimicrobials is unproven, and treatment with these agents is ineffective against C. difficile in asymptomatic carriers...
  19. ncbi request reprint Control of nosocomial methicillin-resistant Staphylococcus aureus infection
    Carlene A Muto
    Clin Infect Dis 43:387-8. 2006
  20. ncbi request reprint Why are antibiotic-resistant nosocomial infections spiraling out of control?
    Carlene A Muto
    Infect Control Hosp Epidemiol 26:10-2. 2005
  21. ncbi request reprint Pittsburgh Regional Healthcare Initiative: a systems approach for achieving perfect patient care
    Carl A Sirio
    University of Pittsburgh Schools of Medicine and Pharmacy, USA
    Health Aff (Millwood) 22:157-65. 2003
    ..This paper describes PRHI's design for change, reviews the progress and limitations of the shared learning model, and offers a set of broader policy considerations...
  22. ncbi request reprint Has methicillin-resistant Staphylococcus aureus stopped spreading in intensive care units?
    Carlene A Muto
    Clin Infect Dis 41:269-70; author reply 270-1. 2005
  23. ncbi request reprint Methicillin-resistant Staphylococcus aureus control: we didn't start the fire, but it's time to put it out
    Carlene A Muto
    Infect Control Hosp Epidemiol 27:111-5. 2006
  24. doi request reprint Antimicrobial-associated risk factors for Clostridium difficile infection
    Robert C Owens
    Maine Medical Center, Portland, ME 04102, USA
    Clin Infect Dis 46:S19-31. 2008
    ....
  25. pmc Acquisition of rectal colonization by vancomycin-resistant Enterococcus among intensive care unit patients treated with piperacillin-tazobactam versus those receiving cefepime-containing antibiotic regimens
    David L Paterson
    Royal Brisbane and Women s Hospital, University of Queensland, Brisbane, Australia
    Antimicrob Agents Chemother 52:465-9. 2008
    ..Although piperacillin-tazobactam inhibits the establishment of VRE colonization in mice when exposure occurs during treatment, our data suggest that this agent may not prevent the acquisition of VRE in patients...
  26. ncbi request reprint Cost-effectiveness of perirectal surveillance cultures for controlling vancomycin-resistant Enterococcus
    Carlene A Muto
    University of Virginia Health System, Charlottesville 22908, USA
    Infect Control Hosp Epidemiol 23:429-35. 2002
    ....