Chandra V, Bortnick A, Murre C. AID targeting: old mysteries and new challenges. Trends Immunol. 2015;36:527-35 pubmed publisher
..Within this framework we discuss gaps in understanding, and outline important areas of further research. ..
Murre C. A Common Mechanism that Underpins Antibody Diversification. Cell. 2015;163:1055-1056 pubmed publisher
..These lead to either point mutations in V exons in somatic hypermutation or deletion of intervening DNA sequences during class switch recombination. ..
Murre C. Ensuring an equal playing field for antigen receptor loci variable regions. J Exp Med. 2015;212:2 pubmed publisher
Isoda T, Moore A, He Z, Chandra V, Aida M, Denholtz M, et al. Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate. Cell. 2017;171:103-119.e18 pubmed publisher
..These data indicate how, during developmental progression and tumor suppression, non-coding transcription orchestrates chromatin folding and compartmentalization to direct with high precision enhancer-promoter communication. ..