Research Topics
| T K MurphySummaryAffiliation: University of South Florida Country: USA Publications
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Publications
Clinical factors associated with pediatric autoimmune neuropsychiatric disorders associated with streptococcal infectionsTanya K Murphy
Department of Pediatrics, University of South Florida, St Petersburg, FL 33701, USA
J Pediatr 160:314-9. 2012..To explore associated clinical factors in children with pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS)...
Open label aripiprazole in the treatment of youth with tic disordersTanya K Murphy
Department of Pediatrics and Psychiatry, University of South Florida, St Petersburg, FL 33701, USA
J Child Adolesc Psychopharmacol 19:441-7. 2009....- Maternal history of autoimmune disease in children presenting with tics and/or obsessive-compulsive disorderT K Murphy
Department of Pediatrics, University of South Florida, College of Medicine, St Petersburg, FL 33701, USA
J Neuroimmunol 229:243-7. 2010..We also expected maternal prevalence of various autoimmune diseases to be higher among those participants that met the putative criteria for PANDAS... - The immunobiology of Tourette's disorder, pediatric autoimmune neuropsychiatric disorders associated with Streptococcus, and related disorders: a way forwardTanya K Murphy
Department of Pediatrics and Psychiatry, University of South Florida, St Petersburg, Florida 33701, USA
J Child Adolesc Psychopharmacol 20:317-31. 2010..Considering the overlap of clinical and neuroanatomic findings among these disorders, this review explores evidence regarding the immunobiology as well as the relevant clinical and therapeutic aspects of TD, OCD, and PANDAS... - An open trial of intensive family based cognitive-behavioral therapy in youth with obsessive-compulsive disorder who are medication partial responders or nonrespondersEric A Storch
Departments of Pediatrics and Psychiatry, University of South Florida, Columbia, SC 29208, USA
J Clin Child Adolesc Psychol 39:260-8. 2010..Significant reductions in OCD-related impairment, depressive symptoms, behavioral problems, and family accommodation were noted. No significant difference in youth-reported anxiety was found... 
Reliability and validity of the Yale Global Tic Severity ScaleEric A Storch
Department of Pediatrics, University of Florida, Gainesville, 32610, USA
Psychol Assess 17:486-91. 2005..07-.20), and child ratings of depression (r = .02-.26) and anxiety (r = -.06 -.28). Findings suggest that the YGTSS is a reliable and valid instrument for the assessment of pediatric TS...- Factors associated with poor response in cognitive-behavioral therapy for pediatric obsessive-compulsive disorderEric A Storch
Department of Pediatrics, University of South Florida College of Medicine, St Petersburg, FL 33701, USA
Bull Menninger Clin 74:167-85. 2010..Remarkably, CBT for OCD is robust to these encumbrances in the majority of cases, despite the need for protocol modifications to tailor treatment to the individual child... - Defining treatment response and remission in obsessive-compulsive disorder: a signal detection analysis of the Children's Yale-Brown Obsessive Compulsive ScaleEric A Storch
Department of Pediatrics, Rothman Center for Neuropsychiatry, University of South Florida, 800 6th Street South, 4th Floor, St Petersburg, FL 33701, USA
J Am Acad Child Adolesc Psychiatry 49:708-17. 2010..To examine the optimal Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS) percent reduction cutoffs for predicting treatment response and clinical remission among children and adolescents with obsessive-compulsive disorder (OCD)... - Understudied clinical dimensions in pediatric obsessive compulsive disorderAdam B Lewin
Department of Pediatrics, Rothman Center for Neuropsychiatry, University of South Florida College of Medicine, 800 Sixth Street South, Saint Petersburg, FL 33701, USA
Child Psychiatry Hum Dev 41:675-91. 2010..Implications for clinicians are discussed... - A preliminary study of D-cycloserine augmentation of cognitive-behavioral therapy in pediatric obsessive-compulsive disorderEric A Storch
Department of Pediatrics and Psychiatry, Rothman Center for Neuropsychiatry, University of South Florida, St Petersburg, FL 33701, USA
Biol Psychiatry 68:1073-6. 2010..Thus, we sought to preliminarily examine whether weight-adjusted DCS doses (25 or 50 mg) enhanced the overall efficacy of cognitive-behavioral therapy (CBT) for pediatric obsessive-compulsive disorder (OCD)... - Refining clinical judgment of treatment outcome in obsessive-compulsive disorderAdam B Lewin
Department of Pediatrics, Rothman Center for Neuropsychiatry, University of South Florida College of Medicine, Saint Petersburg, FL, USA
Psychiatry Res 185:394-401. 2011..This research provides the first empirical contrast of optimal outcome criteria in OCD based on differing ideals of both research and practice... - Development and preliminary psychometric evaluation of the Children's Saving InventoryEric A Storch
Department of Pediatrics, University of South Florida, 800 6th Street South 4th Floor, St, Petersburg, FL 33701, USA
Child Psychiatry Hum Dev 42:166-82. 2011..These findings provide initial support for the reliability and validity of the CSI for the assessment of hoarding behaviors among youth with OCD. Future studies are needed to extend these findings to non-OCD samples of youth... - The roles of anxiety and depression in connecting tic severity and functional impairmentAdam B Lewin
Department of Pediatrics, Rothman Center for Neuropsychiatry, University of South Florida College of Medicine, Saint Petersburg, FL 33701, United States
J Anxiety Disord 25:164-8. 2011..Limitations and implications for research and clinical practice are discussed... - The role of comorbid disruptive behavior in the clinical expression of pediatric obsessive-compulsive disorderEric A Storch
University of South Florida College of Medicine, Department of Pediatrics, Tampa, FL 33701, USA
Behav Res Ther 48:1204-10. 2010..The present results suggest that comorbid DBD contributes to more severe illness presentation above and beyond an OCD diagnosis alone, and may be associated with differing pharmacotherapy prescribing practices... - Compulsive hoarding in childrenEric A Storch
Department of Pediatrics, University of South Florida, 800 6th Street, South, Box 7523, St Petersburg, FL 33701, USA
J Clin Psychol 67:507-16. 2011..We conclude with recommendations for clinical work with this challenging and neglected population... - Development and psychometric evaluation of the Yale-Brown Obsessive-Compulsive Scale--Second EditionEric A Storch
Department of Pediatrics, University of South Florida, St Petersburg, FL 33701, USA
Psychol Assess 22:223-32. 2010..Although the Y-BOCS remains a reliable and valid measure, the Y-BOCS-II may provide an alternative method of assessing symptom presence and severity... - Psychometric analysis of the Yale-Brown Obsessive-Compulsive Scale Second Edition Symptom ChecklistEric A Storch
Department of Pediatrics, University of South Florida, St Petersburg, FL 33701, USA
J Anxiety Disord 24:650-6. 2010..Overall, the Y-BOCS-II-SC shows good psychometric properties; we highlight several domains in which the Y-BOCS-II-SC may have clinical and research utility, as well as several areas for future study... - A preliminary analysis of the phenomenology of skin-picking in Prader-Willi syndromeJessica R Morgan
Department of Pediatrics, University of South Florida, 800 6th Street South, St Petersburg, FL 33701, USA
Child Psychiatry Hum Dev 41:448-63. 2010..The prevalence and consequences associated with skin-picking in PWS indicate a greater need for clinician awareness of the behavior and interventions tailored to meet the needs of this population... - Factor analytic study of the Children's Yale-Brown Obsessive-Compulsive ScaleEric A Storch
Department of Pediatrics, University of Florida, Gainesvile, FL 32610, USA
J Clin Child Adolesc Psychol 34:312-9. 2005..These findings suggest that the CY-BOCS Total Score may represent an inaccurate assessment of symptom severity and supports the use of the revised Severity and Disturbance factors in assessing illness severity... - Obsessive-compulsive disorder in youth with and without a chronic tic disorderEric A Storch
Department of Psychiatry, University of Florida, Gainesville, Florida 32610, USA
Depress Anxiety 25:761-7. 2008..Implications of these findings on clinical presentation and treatment efficacy are highlighted... - Children's Florida Obsessive Compulsive Inventory: psychometric properties and feasibility of a self-report measure of obsessive-compulsive symptoms in youthEric A Storch
Department of Pediatrics, University of South Florida, St Petersburg, FL 33701, USA
Child Psychiatry Hum Dev 40:467-83. 2009..Taken together, the findings of Studies 1 and 2 provide initial support for the reliability and validity of the C-FOCI for the assessment of pediatric obsessive-compulsive symptoms... - Behavioral treatment of trichotillomania and trichophagia in a 29-month-old girlOmar Rahman
Department of Pediatrics, University of South Florida, St Petersburg, Florida 33701, USA
Clin Pediatr (Phila) 48:951-3. 2009..At the end of initial treatment, the hair pulling improved significantly. At follow-up, although some of the initial treatment gains were reduced, the patient maintained significant improvement compared with baseline... - Psychotherapy for obsessive-compulsive disorderEric A Storch
Department of Pediatrics, University of South Florida, 800 6th Street South, Box 7523, St Petersburg, FL 33701, USA
Curr Psychiatry Rep 11:296-301. 2009..This article reviews the nature of CBT and associated outcome data, highlighting recent empiric findings in the treatment literature... - Predictors of functional impairment in pediatric obsessive-compulsive disorderEric A Storch
Department of Pediatrics, University of South Florida, St Petersburg, FL 33701, United States
J Anxiety Disord 24:275-83. 2010..Assessment and treatment implications are discussed; specifically, we highlight how the variables of interest may impact clinical presentation and treatment course... - Does cognitive-behavioral therapy response among adults with obsessive-compulsive disorder differ as a function of certain comorbidities?Eric A Storch
Department of Pediatrics, University of South Florida School of Medicine, Rothman Center for Neuropsychiatry, 800 Sixth Street South, St Petersburg, FL, USA
J Anxiety Disord 24:547-52. 2010..These data suggest that CBT for OCD is robust to the presence of certain common Axis-I comorbidities... - The children's Yale-Brown obsessive-compulsive scale: psychometric properties of child- and parent-report formatsEric A Storch
Department of Pediatrics, University of Florida, Gainesville, FL 32610, USA
J Anxiety Disord 20:1055-70. 2006..Exploratory factor analyses identified a two-factor structure in both measures comprised of disturbance and severity factors. This study provides preliminary support for the use of child- and parent-report versions of the CY-BOCS... - Reliability and validity of the Child Behavior Checklist Obsessive-Compulsive ScaleEric A Storch
Department of Pediatrics, University of Florida, Gainesville, 32610, USA
J Anxiety Disord 20:473-85. 2006..Suggestions for cutoff scores are provided using results from ROC analyses. Overall, these findings suggest that the OCS-R is a reliable and valid instrument for the assessment of pediatric OCD... - Relationship of movements and behaviors to Group A Streptococcus infections in elementary school childrenTanya K Murphy
Department of Psychiatry, College of Medicine, Gainesville, Florida 32610, USA
Biol Psychiatry 61:279-84. 2007..Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcus (PANDAS) research is based on the hypothesis that infections trigger changes in behavior and movement in children... - Yale-Brown Obsessive Compulsive Scale: the dimensional structure revisitedEric A Storch
Department of Pediatrics, University of Florida, Gainesville, Florida 32610, USA
Depress Anxiety 22:28-35. 2005..Reliability and convergent validity of these factors were generally satisfactory, although divergent validity was not entirely supported. Implications of these findings on scoring the Y-BOCS are discussed... - A double-blind, placebo-controlled trial of olanzapine addition in fluoxetine-refractory obsessive-compulsive disorderNathan A Shapira
Department of Psychiatry, College of Medicine, University of Florida, Gainesville, Florida 32610-0256, USA
Biol Psychiatry 55:553-5. 2004..CONCLUSIONS: These findings indicate no additional advantage of adding olanzapine for 6 weeks in OCD patients who have not had a satisfactory response to fluoxetine for 8 weeks, compared with extending the monotherapy trial...