T K Murphy

Summary

Affiliation: University of South Florida
Country: USA

Publications

  1. pmc Tonsillectomies and adenoidectomies do not prevent the onset of pediatric autoimmune neuropsychiatric disorder associated with group a streptococcus
    Tanya K Murphy
    From the Department of Pediatrics, University of South Florida, St Petersburg and Department of Psychiatry and Behavioral Neurosciences, University of South Florida, Tampa, FL
    Pediatr Infect Dis J 32:834-8. 2013
  2. pmc Clinical factors associated with pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections
    Tanya K Murphy
    Department of Pediatrics, University of South Florida, St Petersburg, FL 33701, USA
    J Pediatr 160:314-9. 2012
  3. doi request reprint Open label aripiprazole in the treatment of youth with tic disorders
    Tanya K Murphy
    Department of Pediatrics and Psychiatry, University of South Florida, St Petersburg, FL 33701, USA
    J Child Adolesc Psychopharmacol 19:441-7. 2009
  4. pmc Maternal history of autoimmune disease in children presenting with tics and/or obsessive-compulsive disorder
    T K Murphy
    Department of Pediatrics, University of South Florida, College of Medicine, St Petersburg, FL 33701, USA
    J Neuroimmunol 229:243-7. 2010
  5. doi request reprint The immunobiology of Tourette's disorder, pediatric autoimmune neuropsychiatric disorders associated with Streptococcus, and related disorders: a way forward
    Tanya K Murphy
    Department of Pediatrics and Psychiatry, University of South Florida, St Petersburg, Florida 33701, USA
    J Child Adolesc Psychopharmacol 20:317-31. 2010
  6. doi request reprint An open trial of intensive family based cognitive-behavioral therapy in youth with obsessive-compulsive disorder who are medication partial responders or nonresponders
    Eric A Storch
    Departments of Pediatrics and Psychiatry, University of South Florida, Columbia, SC 29208, USA
    J Clin Child Adolesc Psychol 39:260-8. 2010
  7. ncbi request reprint Reliability and validity of the Yale Global Tic Severity Scale
    Eric A Storch
    Department of Pediatrics, University of Florida, Gainesville, 32610, USA
    Psychol Assess 17:486-91. 2005
  8. doi request reprint Understudied clinical dimensions in pediatric obsessive compulsive disorder
    Adam B Lewin
    Department of Pediatrics, Rothman Center for Neuropsychiatry, University of South Florida College of Medicine, 800 Sixth Street South, Saint Petersburg, FL 33701, USA
    Child Psychiatry Hum Dev 41:675-91. 2010
  9. doi request reprint Defining treatment response and remission in obsessive-compulsive disorder: a signal detection analysis of the Children's Yale-Brown Obsessive Compulsive Scale
    Eric A Storch
    Department of Pediatrics, Rothman Center for Neuropsychiatry, University of South Florida, 800 6th Street South, 4th Floor, St Petersburg, FL 33701, USA
    J Am Acad Child Adolesc Psychiatry 49:708-17. 2010
  10. doi request reprint Factors associated with poor response in cognitive-behavioral therapy for pediatric obsessive-compulsive disorder
    Eric A Storch
    Department of Pediatrics, University of South Florida College of Medicine, St Petersburg, FL 33701, USA
    Bull Menninger Clin 74:167-85. 2010

Detail Information

Publications31

  1. pmc Tonsillectomies and adenoidectomies do not prevent the onset of pediatric autoimmune neuropsychiatric disorder associated with group a streptococcus
    Tanya K Murphy
    From the Department of Pediatrics, University of South Florida, St Petersburg and Department of Psychiatry and Behavioral Neurosciences, University of South Florida, Tampa, FL
    Pediatr Infect Dis J 32:834-8. 2013
    ..Our objective was to examine whether removal of the tonsils and/or adenoids impacted streptococcal antibody titers, the timing of onset of OCD and/or tics and the clinical severity of these symptoms...
  2. pmc Clinical factors associated with pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections
    Tanya K Murphy
    Department of Pediatrics, University of South Florida, St Petersburg, FL 33701, USA
    J Pediatr 160:314-9. 2012
    ..To explore associated clinical factors in children with pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS)...
  3. doi request reprint Open label aripiprazole in the treatment of youth with tic disorders
    Tanya K Murphy
    Department of Pediatrics and Psychiatry, University of South Florida, St Petersburg, FL 33701, USA
    J Child Adolesc Psychopharmacol 19:441-7. 2009
    ....
  4. pmc Maternal history of autoimmune disease in children presenting with tics and/or obsessive-compulsive disorder
    T K Murphy
    Department of Pediatrics, University of South Florida, College of Medicine, St Petersburg, FL 33701, USA
    J Neuroimmunol 229:243-7. 2010
    ..We also expected maternal prevalence of various autoimmune diseases to be higher among those participants that met the putative criteria for PANDAS...
  5. doi request reprint The immunobiology of Tourette's disorder, pediatric autoimmune neuropsychiatric disorders associated with Streptococcus, and related disorders: a way forward
    Tanya K Murphy
    Department of Pediatrics and Psychiatry, University of South Florida, St Petersburg, Florida 33701, USA
    J Child Adolesc Psychopharmacol 20:317-31. 2010
    ..Considering the overlap of clinical and neuroanatomic findings among these disorders, this review explores evidence regarding the immunobiology as well as the relevant clinical and therapeutic aspects of TD, OCD, and PANDAS...
  6. doi request reprint An open trial of intensive family based cognitive-behavioral therapy in youth with obsessive-compulsive disorder who are medication partial responders or nonresponders
    Eric A Storch
    Departments of Pediatrics and Psychiatry, University of South Florida, Columbia, SC 29208, USA
    J Clin Child Adolesc Psychol 39:260-8. 2010
    ..Significant reductions in OCD-related impairment, depressive symptoms, behavioral problems, and family accommodation were noted. No significant difference in youth-reported anxiety was found...
  7. ncbi request reprint Reliability and validity of the Yale Global Tic Severity Scale
    Eric A Storch
    Department of Pediatrics, University of Florida, Gainesville, 32610, USA
    Psychol Assess 17:486-91. 2005
    ..07-.20), and child ratings of depression (r = .02-.26) and anxiety (r = -.06 -.28). Findings suggest that the YGTSS is a reliable and valid instrument for the assessment of pediatric TS...
  8. doi request reprint Understudied clinical dimensions in pediatric obsessive compulsive disorder
    Adam B Lewin
    Department of Pediatrics, Rothman Center for Neuropsychiatry, University of South Florida College of Medicine, 800 Sixth Street South, Saint Petersburg, FL 33701, USA
    Child Psychiatry Hum Dev 41:675-91. 2010
    ..Implications for clinicians are discussed...
  9. doi request reprint Defining treatment response and remission in obsessive-compulsive disorder: a signal detection analysis of the Children's Yale-Brown Obsessive Compulsive Scale
    Eric A Storch
    Department of Pediatrics, Rothman Center for Neuropsychiatry, University of South Florida, 800 6th Street South, 4th Floor, St Petersburg, FL 33701, USA
    J Am Acad Child Adolesc Psychiatry 49:708-17. 2010
    ..To examine the optimal Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS) percent reduction cutoffs for predicting treatment response and clinical remission among children and adolescents with obsessive-compulsive disorder (OCD)...
  10. doi request reprint Factors associated with poor response in cognitive-behavioral therapy for pediatric obsessive-compulsive disorder
    Eric A Storch
    Department of Pediatrics, University of South Florida College of Medicine, St Petersburg, FL 33701, USA
    Bull Menninger Clin 74:167-85. 2010
    ..Remarkably, CBT for OCD is robust to these encumbrances in the majority of cases, despite the need for protocol modifications to tailor treatment to the individual child...
  11. pmc A preliminary study of D-cycloserine augmentation of cognitive-behavioral therapy in pediatric obsessive-compulsive disorder
    Eric A Storch
    Department of Pediatrics and Psychiatry, Rothman Center for Neuropsychiatry, University of South Florida, St Petersburg, FL 33701, USA
    Biol Psychiatry 68:1073-6. 2010
    ..Thus, we sought to preliminarily examine whether weight-adjusted DCS doses (25 or 50 mg) enhanced the overall efficacy of cognitive-behavioral therapy (CBT) for pediatric obsessive-compulsive disorder (OCD)...
  12. doi request reprint Refining clinical judgment of treatment outcome in obsessive-compulsive disorder
    Adam B Lewin
    Department of Pediatrics, Rothman Center for Neuropsychiatry, University of South Florida College of Medicine, Saint Petersburg, FL, USA
    Psychiatry Res 185:394-401. 2011
    ..This research provides the first empirical contrast of optimal outcome criteria in OCD based on differing ideals of both research and practice...
  13. doi request reprint Development and preliminary psychometric evaluation of the Children's Saving Inventory
    Eric A Storch
    Department of Pediatrics, University of South Florida, 800 6th Street South 4th Floor, St, Petersburg, FL 33701, USA
    Child Psychiatry Hum Dev 42:166-82. 2011
    ..These findings provide initial support for the reliability and validity of the CSI for the assessment of hoarding behaviors among youth with OCD. Future studies are needed to extend these findings to non-OCD samples of youth...
  14. doi request reprint The roles of anxiety and depression in connecting tic severity and functional impairment
    Adam B Lewin
    Department of Pediatrics, Rothman Center for Neuropsychiatry, University of South Florida College of Medicine, Saint Petersburg, FL 33701, United States
    J Anxiety Disord 25:164-8. 2011
    ..Limitations and implications for research and clinical practice are discussed...
  15. doi request reprint The role of comorbid disruptive behavior in the clinical expression of pediatric obsessive-compulsive disorder
    Eric A Storch
    University of South Florida College of Medicine, Department of Pediatrics, Tampa, FL 33701, USA
    Behav Res Ther 48:1204-10. 2010
    ..The present results suggest that comorbid DBD contributes to more severe illness presentation above and beyond an OCD diagnosis alone, and may be associated with differing pharmacotherapy prescribing practices...
  16. doi request reprint Compulsive hoarding in children
    Eric A Storch
    Department of Pediatrics, University of South Florida, 800 6th Street, South, Box 7523, St Petersburg, FL 33701, USA
    J Clin Psychol 67:507-16. 2011
    ..We conclude with recommendations for clinical work with this challenging and neglected population...
  17. doi request reprint Development and psychometric evaluation of the Yale-Brown Obsessive-Compulsive Scale--Second Edition
    Eric A Storch
    Department of Pediatrics, University of South Florida, St Petersburg, FL 33701, USA
    Psychol Assess 22:223-32. 2010
    ..Although the Y-BOCS remains a reliable and valid measure, the Y-BOCS-II may provide an alternative method of assessing symptom presence and severity...
  18. doi request reprint Psychometric analysis of the Yale-Brown Obsessive-Compulsive Scale Second Edition Symptom Checklist
    Eric A Storch
    Department of Pediatrics, University of South Florida, St Petersburg, FL 33701, USA
    J Anxiety Disord 24:650-6. 2010
    ..Overall, the Y-BOCS-II-SC shows good psychometric properties; we highlight several domains in which the Y-BOCS-II-SC may have clinical and research utility, as well as several areas for future study...
  19. ncbi request reprint Factor analytic study of the Children's Yale-Brown Obsessive-Compulsive Scale
    Eric A Storch
    Department of Pediatrics, University of Florida, Gainesvile, FL 32610, USA
    J Clin Child Adolesc Psychol 34:312-9. 2005
    ..These findings suggest that the CY-BOCS Total Score may represent an inaccurate assessment of symptom severity and supports the use of the revised Severity and Disturbance factors in assessing illness severity...
  20. ncbi request reprint Obsessive-compulsive disorder in youth with and without a chronic tic disorder
    Eric A Storch
    Department of Psychiatry, University of Florida, Gainesville, Florida 32610, USA
    Depress Anxiety 25:761-7. 2008
    ..Implications of these findings on clinical presentation and treatment efficacy are highlighted...
  21. doi request reprint Children's Florida Obsessive Compulsive Inventory: psychometric properties and feasibility of a self-report measure of obsessive-compulsive symptoms in youth
    Eric A Storch
    Department of Pediatrics, University of South Florida, St Petersburg, FL 33701, USA
    Child Psychiatry Hum Dev 40:467-83. 2009
    ..Taken together, the findings of Studies 1 and 2 provide initial support for the reliability and validity of the C-FOCI for the assessment of pediatric obsessive-compulsive symptoms...
  22. doi request reprint Behavioral treatment of trichotillomania and trichophagia in a 29-month-old girl
    Omar Rahman
    Department of Pediatrics, University of South Florida, St Petersburg, Florida 33701, USA
    Clin Pediatr (Phila) 48:951-3. 2009
    ..At the end of initial treatment, the hair pulling improved significantly. At follow-up, although some of the initial treatment gains were reduced, the patient maintained significant improvement compared with baseline...
  23. ncbi request reprint Psychotherapy for obsessive-compulsive disorder
    Eric A Storch
    Department of Pediatrics, University of South Florida, 800 6th Street South, Box 7523, St Petersburg, FL 33701, USA
    Curr Psychiatry Rep 11:296-301. 2009
    ..This article reviews the nature of CBT and associated outcome data, highlighting recent empiric findings in the treatment literature...
  24. doi request reprint Predictors of functional impairment in pediatric obsessive-compulsive disorder
    Eric A Storch
    Department of Pediatrics, University of South Florida, St Petersburg, FL 33701, United States
    J Anxiety Disord 24:275-83. 2010
    ..Assessment and treatment implications are discussed; specifically, we highlight how the variables of interest may impact clinical presentation and treatment course...
  25. doi request reprint Does cognitive-behavioral therapy response among adults with obsessive-compulsive disorder differ as a function of certain comorbidities?
    Eric A Storch
    Department of Pediatrics, University of South Florida School of Medicine, Rothman Center for Neuropsychiatry, 800 Sixth Street South, St Petersburg, FL, USA
    J Anxiety Disord 24:547-52. 2010
    ..These data suggest that CBT for OCD is robust to the presence of certain common Axis-I comorbidities...
  26. doi request reprint A preliminary analysis of the phenomenology of skin-picking in Prader-Willi syndrome
    Jessica R Morgan
    Department of Pediatrics, University of South Florida, 800 6th Street South, St Petersburg, FL 33701, USA
    Child Psychiatry Hum Dev 41:448-63. 2010
    ..The prevalence and consequences associated with skin-picking in PWS indicate a greater need for clinician awareness of the behavior and interventions tailored to meet the needs of this population...
  27. ncbi request reprint The children's Yale-Brown obsessive-compulsive scale: psychometric properties of child- and parent-report formats
    Eric A Storch
    Department of Pediatrics, University of Florida, Gainesville, FL 32610, USA
    J Anxiety Disord 20:1055-70. 2006
    ..Exploratory factor analyses identified a two-factor structure in both measures comprised of disturbance and severity factors. This study provides preliminary support for the use of child- and parent-report versions of the CY-BOCS...
  28. ncbi request reprint Reliability and validity of the Child Behavior Checklist Obsessive-Compulsive Scale
    Eric A Storch
    Department of Pediatrics, University of Florida, Gainesville, 32610, USA
    J Anxiety Disord 20:473-85. 2006
    ..Suggestions for cutoff scores are provided using results from ROC analyses. Overall, these findings suggest that the OCS-R is a reliable and valid instrument for the assessment of pediatric OCD...
  29. ncbi request reprint Relationship of movements and behaviors to Group A Streptococcus infections in elementary school children
    Tanya K Murphy
    Department of Psychiatry, College of Medicine, Gainesville, Florida 32610, USA
    Biol Psychiatry 61:279-84. 2007
    ..Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcus (PANDAS) research is based on the hypothesis that infections trigger changes in behavior and movement in children...
  30. ncbi request reprint Yale-Brown Obsessive Compulsive Scale: the dimensional structure revisited
    Eric A Storch
    Department of Pediatrics, University of Florida, Gainesville, Florida 32610, USA
    Depress Anxiety 22:28-35. 2005
    ..Reliability and convergent validity of these factors were generally satisfactory, although divergent validity was not entirely supported. Implications of these findings on scoring the Y-BOCS are discussed...
  31. ncbi request reprint A double-blind, placebo-controlled trial of olanzapine addition in fluoxetine-refractory obsessive-compulsive disorder
    Nathan A Shapira
    Department of Psychiatry, College of Medicine, University of Florida, Gainesville, Florida 32610 0256, USA
    Biol Psychiatry 55:553-5. 2004
    ..One of the few combination approaches to the treatment of obsessive-compulsive disorder (OCD) with encouraging support is the addition of an antipsychotic to a serotonin reuptake inhibitor...