Susan A Murphy

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. ncbi request reprint A strategy for optimizing and evaluating behavioral interventions
    Linda M Collins
    The Methodology Center, Department of Human Development and Family Studies, The Pennsylvania State University, University Park 16802, USA
    Ann Behav Med 30:65-73. 2005
  2. pmc Developing adaptive treatment strategies in substance abuse research
    Susan A Murphy
    University of Michigan, Institute for Social Research, Ann Arbor, MI 48106 1248, USA
    Drug Alcohol Depend 88:S24-30. 2007
  3. ncbi request reprint An experimental design for the development of adaptive treatment strategies
    S A Murphy
    Department of Statistics, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA
    Stat Med 24:1455-81. 2005
  4. ncbi request reprint Methodological challenges in constructing effective treatment sequences for chronic psychiatric disorders
    Susan A Murphy
    Institute for Social Research, University of Michigan, Ann Arbor, MI 48106 1248, USA
    Neuropsychopharmacology 32:257-62. 2007
  5. pmc Q-learning: a data analysis method for constructing adaptive interventions
    Inbal Nahum-Shani
    Institute for Social Research, University of Michigan, Ann Arbor, MI 48106, USA
    Psychol Methods 17:478-94. 2012
  6. pmc SMARTer discontinuation trial designs for developing an adaptive treatment strategy
    Daniel Almirall
    1 Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan
    J Child Adolesc Psychopharmacol 22:364-74. 2012
  7. doi request reprint Experimental design and primary data analysis methods for comparing adaptive interventions
    Inbal Nahum-Shani
    Institute for Social Research, University of Michigan, Ann Arbor, MI 48106, USA
    Psychol Methods 17:457-77. 2012
  8. pmc Subgroups analysis when treatment and moderators are time-varying
    Daniel Almirall
    Institute for Social Research, University of Michigan, 426 Thompson Street, Suite 2204, Ann Arbor, Mi 48104 2321, USA
    Prev Sci 14:169-78. 2013
  9. pmc Developing multicomponent interventions using fractional factorial designs
    Bibhas Chakraborty
    Department of Statistics and The Institute for Social Research, University of Michigan, Ann Arbor, MI, USA
    Stat Med 28:2687-708. 2009
  10. pmc Customizing treatment to the patient: adaptive treatment strategies
    Susan A Murphy
    Drug Alcohol Depend 88:S1-3. 2007

Research Grants

Collaborators

Detail Information

Publications14

  1. ncbi request reprint A strategy for optimizing and evaluating behavioral interventions
    Linda M Collins
    The Methodology Center, Department of Human Development and Family Studies, The Pennsylvania State University, University Park 16802, USA
    Ann Behav Med 30:65-73. 2005
    ..Purpose: This article suggests a multiphase optimization strategy (MOST) for achieving the dual goals of program optimization and program evaluation in the behavioral intervention field...
  2. pmc Developing adaptive treatment strategies in substance abuse research
    Susan A Murphy
    University of Michigan, Institute for Social Research, Ann Arbor, MI 48106 1248, USA
    Drug Alcohol Depend 88:S24-30. 2007
    ..Simple analyses that can be used with the SMART design are described. Furthermore, the SMART design is compared with standard experimental designs...
  3. ncbi request reprint An experimental design for the development of adaptive treatment strategies
    S A Murphy
    Department of Statistics, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA
    Stat Med 24:1455-81. 2005
    ..This paper advocates the use of sequential multiple assignment randomized trials in the development of adaptive treatment strategies. Both a simple ad hoc method for ascertaining sample sizes and simple analysis methods are provided...
  4. ncbi request reprint Methodological challenges in constructing effective treatment sequences for chronic psychiatric disorders
    Susan A Murphy
    Institute for Social Research, University of Michigan, Ann Arbor, MI 48106 1248, USA
    Neuropsychopharmacology 32:257-62. 2007
    ..Promising designs and methods are surveyed with a focus on those areas most immediately useful for informing clinical decision making...
  5. pmc Q-learning: a data analysis method for constructing adaptive interventions
    Inbal Nahum-Shani
    Institute for Social Research, University of Michigan, Ann Arbor, MI 48106, USA
    Psychol Methods 17:478-94. 2012
    ..Finally, we use the Adaptive Interventions for Children With ADHD SMART study (Center for Children and Families, University at Buffalo, State University of New York, William E. Pelham as principal investigator) for illustration...
  6. pmc SMARTer discontinuation trial designs for developing an adaptive treatment strategy
    Daniel Almirall
    1 Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan
    J Child Adolesc Psychopharmacol 22:364-74. 2012
    ..The objective of this article is to illustrate how a SMART study is related to the standard discontinuation trial design, while addressing additional clinically important questions with similar trial resources...
  7. doi request reprint Experimental design and primary data analysis methods for comparing adaptive interventions
    Inbal Nahum-Shani
    Institute for Social Research, University of Michigan, Ann Arbor, MI 48106, USA
    Psychol Methods 17:457-77. 2012
    ..We also provide methods for analyzing data from SMART to address primary research questions that inform the construction of a high-quality adaptive intervention...
  8. pmc Subgroups analysis when treatment and moderators are time-varying
    Daniel Almirall
    Institute for Social Research, University of Michigan, 426 Thompson Street, Suite 2204, Ann Arbor, Mi 48104 2321, USA
    Prev Sci 14:169-78. 2013
    ..The methodology is illustrated using longitudinal data to examine the time-varying effects of receiving community-based substance abuse treatment as a function of time-varying severity (or need)...
  9. pmc Developing multicomponent interventions using fractional factorial designs
    Bibhas Chakraborty
    Department of Statistics and The Institute for Social Research, University of Michigan, Ann Arbor, MI, USA
    Stat Med 28:2687-708. 2009
    ..As an example, we consider the use of a screening study in the development of a multicomponent smoking cessation intervention. Simulation results are provided to support the discussions...
  10. pmc Customizing treatment to the patient: adaptive treatment strategies
    Susan A Murphy
    Drug Alcohol Depend 88:S1-3. 2007
  11. pmc Constructing evidence-based treatment strategies using methods from computer science
    Joelle Pineau
    McGill University, School of Computer Science, Montreal, Que H3A 2A7, Canada
    Drug Alcohol Depend 88:S52-60. 2007
    ..The methodology is illustrated with data from the STAR*D trial, a multi-step randomized study of treatment alternatives for individuals with treatment-resistant major depressive disorder...
  12. pmc Assessing the total effect of time-varying predictors in prevention research
    Bethany Cara Bray
    The Methodology Center, Department of Human Development and Family Studies, The Pennsylvania State University, University Park, Pennsylvania 16801, USA
    Prev Sci 7:1-17. 2006
    ..The above two methods are illustrated by addressing the motivating question. Implications for prevention researchers who wish to estimate total causal effects using longitudinal observational data are discussed...
  13. pmc A conceptual framework for adaptive preventive interventions
    Linda M Collins
    The Methodology Center and Department of Human Development and Family Studies, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Prev Sci 5:185-96. 2004
    ..In this paper, we offer a conceptual framework for adaptive interventions, discuss principles underlying the design and evaluation of such interventions, and review some areas where additional research is needed...
  14. ncbi request reprint Two-level proportional hazards models
    Jerry J Maples
    The Methodology Center and Department of Statistics, Pennsylvania State University, 326 Thomas Building, University Park, Pennsylvania 16802, USA
    Biometrics 58:754-63. 2002
    ..We utilize a two-level hazard model to examine how education and access to education for children covary with the initiation of permanent contraceptive use...

Research Grants7

  1. Methodology for Adaptive Treatment Strategies
    Susan Murphy; Fiscal Year: 2005
    ..We will write a joint position paper identifying the major challenges and potential solutions and we will form small collaborative groups that will work to address these methodological challenges. ..
  2. Reducing Drug Abuse with Individually Tailored Treatment
    Susan Murphy; Fiscal Year: 2006
    ..The K-02 award would enable me to extend this research to the design of individually tailored treatments and to expand the methodology for evaluation of these treatments. ..
  3. Learning Adaptive Treatment Strategies in Mental Health
    Susan Murphy; Fiscal Year: 2007
    ..The methods will be developed and validated using data from two large NIMH funded trials. This project will be conducted by a collaborative team involving a computer scientist, two psychiatrists and a statistician. ..
  4. Learning Adaptive Treatment Strategies in Mental Health
    Susan A Murphy; Fiscal Year: 2010
    ..The methods will be developed and validated using data from two large NIMH funded trials. This project will be conducted by a collaborative team involving a computer scientist, two psychiatrists and a statistician. ..