Susan A Murphy
Affiliation: University of Michigan
- A strategy for optimizing and evaluating behavioral interventionsLinda M Collins
The Methodology Center, Department of Human Development and Family Studies, The Pennsylvania State University, University Park 16802, USA
Ann Behav Med 30:65-73. 2005..Purpose: This article suggests a multiphase optimization strategy (MOST) for achieving the dual goals of program optimization and program evaluation in the behavioral intervention field...
- Developing adaptive treatment strategies in substance abuse researchSusan A Murphy
University of Michigan, Institute for Social Research, Ann Arbor, MI 48106 1248, USA
Drug Alcohol Depend 88:S24-30. 2007..Simple analyses that can be used with the SMART design are described. Furthermore, the SMART design is compared with standard experimental designs...
- Methodological challenges in constructing effective treatment sequences for chronic psychiatric disordersSusan A Murphy
Institute for Social Research, University of Michigan, Ann Arbor, MI 48106 1248, USA
Neuropsychopharmacology 32:257-62. 2007..Promising designs and methods are surveyed with a focus on those areas most immediately useful for informing clinical decision making...
- An experimental design for the development of adaptive treatment strategiesS A Murphy
Department of Statistics, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA
Stat Med 24:1455-81. 2005..This paper advocates the use of sequential multiple assignment randomized trials in the development of adaptive treatment strategies. Both a simple ad hoc method for ascertaining sample sizes and simple analysis methods are provided...
- Developing multicomponent interventions using fractional factorial designsBibhas Chakraborty
Department of Statistics and The Institute for Social Research, University of Michigan, Ann Arbor, MI, USA
Stat Med 28:2687-708. 2009..As an example, we consider the use of a screening study in the development of a multicomponent smoking cessation intervention. Simulation results are provided to support the discussions...
- Assessing the total effect of time-varying predictors in prevention researchBethany Cara Bray
The Methodology Center, Department of Human Development and Family Studies, The Pennsylvania State University, University Park, Pennsylvania 16801, USA
Prev Sci 7:1-17. 2006..The above two methods are illustrated by addressing the motivating question. Implications for prevention researchers who wish to estimate total causal effects using longitudinal observational data are discussed...
- A conceptual framework for adaptive preventive interventionsLinda M Collins
The Methodology Center and Department of Human Development and Family Studies, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
Prev Sci 5:185-96. 2004..In this paper, we offer a conceptual framework for adaptive interventions, discuss principles underlying the design and evaluation of such interventions, and review some areas where additional research is needed...
- Constructing evidence-based treatment strategies using methods from computer scienceJoelle Pineau
McGill University, School of Computer Science, Montreal, Que H3A 2A7, Canada
Drug Alcohol Depend 88:S52-60. 2007..The methodology is illustrated with data from the STAR*D trial, a multi-step randomized study of treatment alternatives for individuals with treatment-resistant major depressive disorder...
- Customizing treatment to the patient: adaptive treatment strategiesSusan A Murphy
Drug Alcohol Depend 88:S1-3. 2007
- Two-level proportional hazards modelsJerry J Maples
The Methodology Center and Department of Statistics, Pennsylvania State University, 326 Thomas Building, University Park, Pennsylvania 16802, USA
Biometrics 58:754-63. 2002..We utilize a two-level hazard model to examine how education and access to education for children covary with the initiation of permanent contraceptive use...
- Methodology for Adaptive Treatment StrategiesSusan Murphy; Fiscal Year: 2005..We will write a joint position paper identifying the major challenges and potential solutions and we will form small collaborative groups that will work to address these methodological challenges. ..
- Reducing Drug Abuse with Individually Tailored TreatmentSusan Murphy; Fiscal Year: 2006..The K-02 award would enable me to extend this research to the design of individually tailored treatments and to expand the methodology for evaluation of these treatments. ..
- Learning Adaptive Treatment Strategies in Mental HealthSusan Murphy; Fiscal Year: 2007..The methods will be developed and validated using data from two large NIMH funded trials. This project will be conducted by a collaborative team involving a computer scientist, two psychiatrists and a statistician. ..
- Learning Adaptive Treatment Strategies in Mental HealthSusan A Murphy; Fiscal Year: 2010..The methods will be developed and validated using data from two large NIMH funded trials. This project will be conducted by a collaborative team involving a computer scientist, two psychiatrists and a statistician. ..