Research Topics
Species | E Angela MurphySummaryAffiliation: University of South Carolina Country: USA Publications
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Detail Information
Publications
Curcumin's effect on intestinal inflammation and tumorigenesis in the ApcMin/+ mouseE Angela Murphy
Department of Pathology Microbiology and Immunology, School of Medicine, University of South Carolina, Columbia, South Carolina 29209, USA
J Interferon Cytokine Res 31:219-26. 2011..05). Curcumin also offset the increase in plasma CCL2 (P < 0.05). The benefits of curcumin in colon cancer may be at least in part mediated by its antiinflammatory activity...
Benefits of oat beta-glucan and sucrose feedings on infection and macrophage antiviral resistance following exercise stressE Angela Murphy
Division of Applied Physiology, Department of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA
Am J Physiol Regul Integr Comp Physiol 297:R1188-94. 2009....
Immune modulating effects of β-glucanE Angela Murphy
Department of Pathology, Microbiology, and Immunology, School of Medicine, University of South Carolina, Columbia, SC 29209, USA
Curr Opin Clin Nutr Metab Care 13:656-61. 2010..To examine the recent scientific literature on the immune modulating effects of β-glucans and subsequent benefits on infection and cancer...
Role of brain macrophages on IL-1beta and fatigue following eccentric exercise-induced muscle damageMartin D Carmichael
Division of Applied Physiology, Department of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA
Brain Behav Immun 24:564-8. 2010..These results suggest that brain macrophages can contribute to the increase in brain IL-1beta and fatigue that are associated with recovery from exercise-induced muscle damage...
Effects of oat β-glucan on the macrophage cytokine response to herpes simplex virus 1 infection in vitroE Angela Murphy
Department of Pathology, Microbiology and Immunology, School of Medicine, University of South Carolina, Columbia, South Carolina 29201, USA
J Interferon Cytokine Res 32:362-7. 2012..This may be a mechanism for the decreased risk for HSV-1 infection following oat β-glucan feedings in mice...
Role of brain IL-1beta on fatigue after exercise-induced muscle damageMartin D Carmichael
Dept of Exercise Science, Arnold School of Public Health, University of South Carolina, 1300 Wheat St, Columbia, SC 29208, USA
Am J Physiol Regul Integr Comp Physiol 291:R1344-8. 2006..01). These results support the hypothesis that increased brain IL-1beta plays an important role in fatigue after muscle-damaging exercise...
Effect of IL-6 deficiency on susceptibility to HSV-1 respiratory infection and intrinsic macrophage antiviral resistanceE Angela Murphy
Division of Applied Physiology, Department of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina 29208, USA
J Interferon Cytokine Res 28:589-95. 2008..001). Results indicate that IL-6 plays an important role in susceptibility to respiratory infection in mice, which may be mediated at least in part by its effect on macrophage antiviral resistance...
Quercetin increases brain and muscle mitochondrial biogenesis and exercise toleranceJ Mark Davis
University of South Carolina, Department of Exercise Science, Columbia, SC 29208, USA
Am J Physiol Regul Integr Comp Physiol 296:R1071-7. 2009..05). These benefits of querectin on fitness without exercise training may have important implications for enhancement of athletic and military performance and may also extend to prevention and/or treatment of chronic diseases...
Linking tumor-associated macrophages, inflammation, and intestinal tumorigenesis: role of MCP-1Jamie L McClellan
Dept of Pathology, Microbiology and Immunology, School of Medicine, Univ of South Carolina, Columbia, SC 29209, USA
Am J Physiol Gastrointest Liver Physiol 303:G1087-95. 2012..05). We demonstrate that MCP-1 is an important mediator of tumor growth and immune regulation that may serve as an important biomarker and/or therapeutic target in colon cancer...
The dietary flavonoid quercetin increases VO(2max) and endurance capacityJ Mark Davis
Div of Applied Physiology, Dept of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA
Int J Sport Nutr Exerc Metab 20:56-62. 2010..This apparent increase in fitness without exercise training may have implications beyond that of performance enhancement to health promotion and disease prevention...
Oat beta-glucan effects on neutrophil respiratory burst activity following exerciseE Angela Murphy
Divison of Applied Physiology, Department of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA
Med Sci Sports Exerc 39:639-44. 2007..Consumption of oat beta-glucan (ObetaG), a soluble fiber and mild immune system enhancer, may offset the immunosuppression associated with intense training and perhaps further enhance the benefits of moderate exercise...
Susceptibility to infection and inflammatory response following influenza virus (H1N1, A/PR/8/34) challenge: role of macrophagesE Angela Murphy
Department of Pathology, Microbiology, and Immunology, School of Medicine, University of South Carolina, Columbia, SC 29209 USA
J Interferon Cytokine Res 31:501-8. 2011..05). These data suggest that macrophages play a necessary role in controlling susceptibility to influenza virus and the host's cytokine-mediated response to influenza infection...
Quercetin's effects on intestinal polyp multiplicity and macrophage number in the Apc(Min/+) mouseE Angela Murphy
Department of Pathology, Microbiology, and Immunology, School of Medicine, University of South Carolina, Columbia, South Carolina 29209, USA
Nutr Cancer 63:421-6. 2011..05). These data suggest that quercetin can reduce polyp number and size distribution in the Apc(Min/+) mouse and that these effects may be related to a reduction in macrophage infiltration...
Exercise training increases mitochondrial biogenesis in the brainJennifer L Steiner
Department of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA
J Appl Physiol 111:1066-71. 2011....
Intestinal inflammatory cytokine response in relation to tumorigenesis in the Apc(Min/+) mouseJamie L McClellan
Department of Pathology, Microbiology and Immunology, School of Medicine, University of South Carolina, Columbia, SC 29209, USA
Cytokine 57:113-9. 2012..Further, these data may be relevant in the design of future investigations of therapeutic interventions to effectively target inflammatory processes in rodent models...
Curcumin effects on inflammation and performance recovery following eccentric exercise-induced muscle damageJ Mark Davis
Division of Applied Physiology, Department of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA
Am J Physiol Regul Integr Comp Physiol 292:R2168-73. 2007..05) that were blunted by curcumin feedings. These results support the hypothesis that curcumin can reduce inflammation and offset some of the performance deficits associated with eccentric exercise-induced muscle damage...
Influence of dietary saturated fat content on adiposity, macrophage behavior, inflammation, and metabolism: composition mattersReilly T Enos
Department of Pathology, Microbiology and Immunology, School of Medicine, University of South Carolina, Columbia, SC, USA
J Lipid Res 54:152-63. 2013..Macrophage behavior, inflammation, and IR following HFD are heavily influenced by dietary SF content; however, these responses are not necessarily proportional to the SF percentage...
Recovery of running performance following muscle-damaging exercise: relationship to brain IL-1betaMartin D Carmichael
Division of Applied Physiology, Department of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, 29205, USA
Brain Behav Immun 19:445-52. 2005....
Effects of the dietary flavonoid quercetin upon performance and healthJ Mark Davis
Division of Applied Physiology, Department of Exercise Science Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA
Curr Sports Med Rep 8:206-13. 2009..This article will examine the recent scientific literature concerning the role of quercetin in mental and physical performance and health...
Importance of chemokine (CC-motif) ligand 2 in breast cancerJennifer L Steiner
Department of Exercise Science, University of South Carolina, Columbia, SC 29209, USA
Int J Biol Markers 27:e179-85. 2012..While there is emerging support for a tumor promoting role of CCL2 in breast cancer, additional research is required before CCL2 can be decisively established as a prognostic factor and/or treatment target in breast cancer...
Carbohydrate feedings during team sport exercise preserve physical and CNS functionJason J Winnick
Department of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA
Med Sci Sports Exerc 37:306-15. 2005..05). CONCLUSION: These results suggest that CHO feedings during intermittent high-intensity exercise similar to that of team sports benefited both peripheral and CNS function late in exercise compared with a flavored placebo...
