Detail Information
Publications
Gene-environment interaction in genome-wide association studiesCassandra E Murcray
Department of Preventive Medicine, University of Southern California, Los Angeles, California 90089 9010, USA
Am J Epidemiol 169:219-26. 2009..The procedure complements screening for marginal genetic effects and thus has the potential to uncover new genetic signals that have not been identified previously...
Sample size requirements to detect gene-environment interactions in genome-wide association studiesCassandra E Murcray
Department of Preventive Medicine, University of Southern California, Los Angeles, California 90089 9010, USA
Genet Epidemiol 35:201-10. 2011..15, and a binary exposure with prevalence 0.3, the Murcray, Kooperberg and hybrid methods are 1.90, 1.27, and 1.87 times as efficient, respectively, as the traditional case-control analysis to detect an interaction effect size of 2.0...
Efficient genome-wide association testing of gene-environment interaction in case-parent triosW James Gauderman
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, 90033, USA
Am J Epidemiol 172:116-22. 2010..This 2-step scan for G x E interaction is independent of any prior scan that may have been conducted for genetic main effects, and thus has the potential to uncover new genes in a GWAS that have not been previously identified...
Invited commentary: GE-Whiz! Ratcheting gene-environment studies up to the whole genome and the whole exposomeDuncan C Thomas
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Am J Epidemiol 175:203-7; discussion 208-9. 2012....
