Dorothy I Mundy

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. ncbi Impact of the loss of caveolin-1 on lung mass and cholesterol metabolism in mice with and without the lysosomal cholesterol transporter, Niemann-Pick type C1
    Dorothy I Mundy
    Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX, USA Electronic address
    Biochim Biophys Acta 1841:995-1002. 2014
  2. pmc Caveolin targeting to late endosome/lysosomal membranes is induced by perturbations of lysosomal pH and cholesterol content
    Dorothy I Mundy
    Department of Internal Medicine Touchstone Diabetes Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Mol Biol Cell 23:864-80. 2012
  3. ncbi Dual control of caveolar membrane traffic by microtubules and the actin cytoskeleton
    Dorothy I Mundy
    Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9039, USA
    J Cell Sci 115:4327-39. 2002
  4. ncbi Chinese hamster ovary K2 cell lipid droplets appear to be metabolic organelles involved in membrane traffic
    Pingsheng Liu
    Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9039, USA
    J Biol Chem 279:3787-92. 2004
  5. pmc Altered mitochondrial function and metabolic inflexibility associated with loss of caveolin-1
    Ingrid Wernstedt Asterholm
    Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 8549, USA
    Cell Metab 15:171-85. 2012

Collaborators

Detail Information

Publications5

  1. ncbi Impact of the loss of caveolin-1 on lung mass and cholesterol metabolism in mice with and without the lysosomal cholesterol transporter, Niemann-Pick type C1
    Dorothy I Mundy
    Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX, USA Electronic address
    Biochim Biophys Acta 1841:995-1002. 2014
    ..The exacerbation of the Npc1 lung phenotype and increase in the UC level in the Cav-1(-/-):Npc1(-/-) mice imply a regulatory role of Cav-1 in pulmonary cholesterol metabolism when lysosomal sterol transport is disrupted. ..
  2. pmc Caveolin targeting to late endosome/lysosomal membranes is induced by perturbations of lysosomal pH and cholesterol content
    Dorothy I Mundy
    Department of Internal Medicine Touchstone Diabetes Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Mol Biol Cell 23:864-80. 2012
    ..We conclude that caveolin-1 normally traffics to and from the cytoplasmic surface of lysosomes during intracellular cholesterol trafficking...
  3. ncbi Dual control of caveolar membrane traffic by microtubules and the actin cytoskeleton
    Dorothy I Mundy
    Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9039, USA
    J Cell Sci 115:4327-39. 2002
    ..The behavior of cavicles suggests that they function as transport intermediates between caveolae and caveosomes...
  4. ncbi Chinese hamster ovary K2 cell lipid droplets appear to be metabolic organelles involved in membrane traffic
    Pingsheng Liu
    Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9039, USA
    J Biol Chem 279:3787-92. 2004
    ..Based on the protein profile, the lipid droplet appears to be a complex, metabolically active organelle that is directly involved in membrane traffic and possibly phospholipid recycling. We propose the name adiposome for this organelle...
  5. pmc Altered mitochondrial function and metabolic inflexibility associated with loss of caveolin-1
    Ingrid Wernstedt Asterholm
    Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 8549, USA
    Cell Metab 15:171-85. 2012
    ..This mouse model highlights the central contributions of adipose tissue for system-wide preservation of metabolic flexibility...