J J Mulchahey
Affiliation: University of Cincinnati
- Cerebrospinal fluid and plasma testosterone levels in post-traumatic stress disorder and tobacco dependenceJ J Mulchahey
Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
Psychoneuroendocrinology 26:273-85. 2001..The goal of this study was to screen for potential abnormalities in CNS testosterone levels in patients with post-traumatic stress disorder (PTSD) and/or tobacco dependence...
- Regulation of corticotropin-releasing factor-binding protein expression in amygdalar neuronal culturesJ W Kasckow
Cincinnati VAMC, Psychiatry Service, Cincinnati, OH 45220, USA
J Neuroendocrinol 11:959-66. 1999..05; n=3 for each). The results suggest that CRF-BP in the amygdala is stimulated by numerous pathways which may play a significant role in promoting behavioural changes...
- Coordinate and divergent regulation of corticotropin-releasing factor (CRF) and CRF-binding protein expression in an immortalized amygdalar neuronal cell lineJ J Mulchahey
Department of Psychiatry, University of Cincinnati College of Medicine, Ohio 45267, USA
Endocrinology 140:251-9. 1999..These data also suggest that dexamethasone may decrease the biological availability of CRF in the amygdala by increasing the expression of CRF-BP, rather than by decreasing CRF expression...
- Changes in brain corticotropin-releasing factor messenger RNA expression in aged Fischer 344 ratsJ W Kasckow
Cincinnati VAMC Psychiatry Service, 3200 Vine Street, Cincinnati, OH 45220, USA
Brain Res 822:228-30. 1999..These changes may contribute to impaired adaptations to stress, cognitive decline and other pathophysiological processes during aging...
- Interaction of neuropeptide Y and corticotropin-releasing factor signaling pathways in AR-5 amygdalar cellsS Sheriff
University of Cincinnati College of Medicine, Department of Surgery, Cincinnati, OH 45267, USA
Peptides 22:2083-9. 2001..These findings suggest that CRF and NPY may counter-regulate each other in amygdalar neurons via reciprocal effects on the protein kinase A pathway...
- Regulation of corticotropin-releasing hormone in vitroM Pisarska
Cincinnati VAMC, Psychiatry Service, 3200 Vine Street, Cincinnati, OH 45220, USA
Peptides 22:705-12. 2001..These mechanistic studies have focused on PKA- and glucocorticoid-mediated changes in CRH expression. Clearly much more investigative work in better understanding CRH regulation in vitro is needed...
- Aging associated changes in amygdalar corticotropin-releasing hormone (CRH) and CRH-binding protein in Fischer 344 ratsC Xiao
University of Cincinnati Department of Surgery, 231 Bethesda Ave, Cincinnati, OH 45267, USA
Brain Res 1073:325-31. 2006..05 via ANOVA and Fisher's PLSD). These changes may contribute to impaired adaptations to stress, cognitive decline, and other pathophysiological processes during aging...
- The effect of feeding on cerebrospinal fluid corticotropin-releasing hormone levels in humansJ W Kasckow
Cincinnati VAMC, Psychiatry Service, 3200 Vine St, Cincinnati, OH 45220, USA
Brain Res 904:218-24. 2001..Alternatively, our findings could also reflect changes in CRH levels associated with feeding in multiple brain areas and in the spinal cord with the net effect being in the negative direction...
- Health-related quality of well-being in chronically hospitalized patients with schizophrenia: comparison with matched outpatientsJ W Kasckow
VA Cincinnati Healthcare System and University of Cincinnati, 231 Bethesda Ave, Cincinnati, OH 45267 0559, USA
Psychiatry Res 103:69-78. 2001..These findings further support the use of the QWB in severely mentally ill populations; implications for improving health-related quality of life among older patients with schizophrenia are discussed...
- Corticotropin-releasing hormone (CRH) expression and protein kinase A mediated CRH receptor signalling in an immortalized hypothalamic cell lineJ Kasckow
Cincinnati VAMC, Psychiatry Service 116A, and School of Medicine, Department of Psychiatry, and Neurosciences Program, University of Cincinnati, OH 45267 0559, USA
J Neuroendocrinol 15:521-9. 2003..The characteristics of IVB cells, such as CRH and VP coexpression, GR expression and a biologically active CRH-R1-mediated signalling pathway, suggest that this neuronal cell line may serve as model of parvocellular CRH neurones...
- Quantification and localization of kainic acid-induced neurotoxicity employing a new biomarker of cell death: cleaved microtubule-associated protein-tau (C-tau)F P Zemlan
Department of Psychiatry, College of Medicine, 231 Sabin Avenue, University of Cincinnati, Cincinnati, OH 45267, USA
Neuroscience 121:399-409. 2003..These data suggest that C-tau proteolysis may prove a reliable species independent biomarker of neuronal degeneration regardless of source of injury...