Sabine Mueller

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Risk of first and recurrent stroke in childhood cancer survivors treated with cranial and cervical radiation therapy
    Sabine Mueller
    Department of Neurology, University of California, San Francisco, California 94148, USA
    Int J Radiat Oncol Biol Phys 86:643-8. 2013
  2. pmc Radiation, atherosclerotic risk factors, and stroke risk in survivors of pediatric cancer: a report from the Childhood Cancer Survivor Study
    Sabine Mueller
    Department of Neurology, Pediatrics and Neurosurgery, University of California, San Francisco, San Francisco, California 94158, USA
    Int J Radiat Oncol Biol Phys 86:649-55. 2013
  3. pmc Poly (ADP-Ribose) polymerase inhibitor MK-4827 together with radiation as a novel therapy for metastatic neuroblastoma
    Sabine Mueller
    Department of Neurology, University of California, San Francisco, 675 Nelson Ring, Sandler Neuroscience Center, UCSF, San Francisco, CA 94148, USA
    Anticancer Res 33:755-62. 2013
  4. pmc Cooperation of the HDAC inhibitor vorinostat and radiation in metastatic neuroblastoma: efficacy and underlying mechanisms
    Sabine Mueller
    Department of Neurology, University of California, San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143 0106, USA
    Cancer Lett 306:223-9. 2011
  5. pmc Effect of imaging and catheter characteristics on clinical outcome for patients in the PRECISE study
    Sabine Mueller
    Department of Neurology, University of San Francisco, 350 Parnassus Ave, Suite 609, San Francisco, CA 94117, USA
    J Neurooncol 101:267-77. 2011
  6. ncbi request reprint Pediatric brain tumors: current treatment strategies and future therapeutic approaches
    Sabine Mueller
    Department of Neurology, Division of Child Neurology, University of San Francisco, San Francisco, California, USA
    Neurotherapeutics 6:570-86. 2009
  7. doi request reprint Feasibility, safety, and indications for surgical biopsy of intrinsic brainstem tumors in children
    Tene A Cage
    Department of Neurological Surgery, Pediatric Neurosurgery, University of California, San Francisco, 505 Parnassus Ave, Room M779, San Francisco, CA 94143 0112, USA
    Childs Nerv Syst 29:1313-9. 2013
  8. doi request reprint High-grade gliomas in children
    Tene A Cage
    Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143 0112, USA
    Neurosurg Clin N Am 23:515-23. 2012
  9. ncbi request reprint The alternative lengthening of telomere phenotype is significantly associated with loss of ATRX expression in high-grade pediatric and adult astrocytomas: a multi-institutional study of 214 astrocytomas
    Malak Abedalthagafi
    1 Division of Neuropathology, Department of Pathology, University of California, San Francisco, San Francisco, CA, USA 2 Division of Surgical Pathology, Department of Pathology, University of California, San Francisco, San Francisco, CA, USA
    Mod Pathol 26:1425-32. 2013
  10. pmc Inhibition of PI3K/mTOR pathways in glioblastoma and implications for combination therapy with temozolomide
    Gautam Prasad
    Department of Radiation Oncology, University of California, San Francisco, San Francisco, CA, USA
    Neuro Oncol 13:384-92. 2011

Detail Information

Publications19

  1. pmc Risk of first and recurrent stroke in childhood cancer survivors treated with cranial and cervical radiation therapy
    Sabine Mueller
    Department of Neurology, University of California, San Francisco, California 94148, USA
    Int J Radiat Oncol Biol Phys 86:643-8. 2013
    ..To assess, in a retrospective cohort study, rates and predictors of first and recurrent stroke in patients treated with cranial irradiation (CRT) and/or cervical irradiation at ≤18 years of age...
  2. pmc Radiation, atherosclerotic risk factors, and stroke risk in survivors of pediatric cancer: a report from the Childhood Cancer Survivor Study
    Sabine Mueller
    Department of Neurology, Pediatrics and Neurosurgery, University of California, San Francisco, San Francisco, California 94158, USA
    Int J Radiat Oncol Biol Phys 86:649-55. 2013
    ..To test the hypotheses that (1) the increased risk of stroke conferred by childhood cranial radiation therapy (CRT) persists into adulthood; and (2) atherosclerotic risk factors further increase the stroke risk in cancer survivors...
  3. pmc Poly (ADP-Ribose) polymerase inhibitor MK-4827 together with radiation as a novel therapy for metastatic neuroblastoma
    Sabine Mueller
    Department of Neurology, University of California, San Francisco, 675 Nelson Ring, Sandler Neuroscience Center, UCSF, San Francisco, CA 94148, USA
    Anticancer Res 33:755-62. 2013
    ..To assess poly (ADP-ribose) polymerase (PARP) inhibitor MK-4827 together with radiation for the treatment of neuroblastoma...
  4. pmc Cooperation of the HDAC inhibitor vorinostat and radiation in metastatic neuroblastoma: efficacy and underlying mechanisms
    Sabine Mueller
    Department of Neurology, University of California, San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143 0106, USA
    Cancer Lett 306:223-9. 2011
    ..DNA repair enzyme Ku-86 was reduced in several neuroblastoma cells treated with vorinostat. Thus, vorinostat potentiates anti-neoplastic effects of radiation in neuroblastoma possibly due to down-regulation of DNA repair enzyme Ku-86...
  5. pmc Effect of imaging and catheter characteristics on clinical outcome for patients in the PRECISE study
    Sabine Mueller
    Department of Neurology, University of San Francisco, 350 Parnassus Ave, Suite 609, San Francisco, CA 94117, USA
    J Neurooncol 101:267-77. 2011
    ..55; PFS: P = 0.35) or imaging changes on day 43 MRI (P = 0.88). Catheter positioning scores and overall catheter placement scores were not associated with clinical outcome in this large prospective trial...
  6. ncbi request reprint Pediatric brain tumors: current treatment strategies and future therapeutic approaches
    Sabine Mueller
    Department of Neurology, Division of Child Neurology, University of San Francisco, San Francisco, California, USA
    Neurotherapeutics 6:570-86. 2009
    ..This article will outline current and future therapeutic strategies for the most common pediatric CNS tumors, including primitive neuroectodermal tumors such as medulloblastoma, as well as astrocytomas and ependymomas...
  7. doi request reprint Feasibility, safety, and indications for surgical biopsy of intrinsic brainstem tumors in children
    Tene A Cage
    Department of Neurological Surgery, Pediatric Neurosurgery, University of California, San Francisco, 505 Parnassus Ave, Room M779, San Francisco, CA 94143 0112, USA
    Childs Nerv Syst 29:1313-9. 2013
    ..We have reviewed the results of biopsy for DIPGs in children at a single institution and compared our results to those available in the literature to elucidate the utility of biopsy for DIPGs...
  8. doi request reprint High-grade gliomas in children
    Tene A Cage
    Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143 0112, USA
    Neurosurg Clin N Am 23:515-23. 2012
    ..This article reviews clinical, diagnostic, and pathologic features of HGG and current treatments and potential future therapies specific to pediatric patients with HGGs...
  9. ncbi request reprint The alternative lengthening of telomere phenotype is significantly associated with loss of ATRX expression in high-grade pediatric and adult astrocytomas: a multi-institutional study of 214 astrocytomas
    Malak Abedalthagafi
    1 Division of Neuropathology, Department of Pathology, University of California, San Francisco, San Francisco, CA, USA 2 Division of Surgical Pathology, Department of Pathology, University of California, San Francisco, San Francisco, CA, USA
    Mod Pathol 26:1425-32. 2013
    ..03 for each). In summary, our data show that the ALT and ATRX protein alterations are common in both pediatric and adult high-grade astrocytomas, often with associated PDGFRA gene amplification. ..
  10. pmc Inhibition of PI3K/mTOR pathways in glioblastoma and implications for combination therapy with temozolomide
    Gautam Prasad
    Department of Radiation Oncology, University of California, San Francisco, San Francisco, CA, USA
    Neuro Oncol 13:384-92. 2011
    ..05) with a trend toward improvement in median survival (logrank p = 0.09) compared with TMZ alone. XL765 shows activity as monotherapy and in combination with conventional therapeutics in a range of genetically diverse GBM xenografts...
  11. ncbi request reprint Targeting Wee1 for the treatment of pediatric high-grade gliomas
    Sabine Mueller
    Department of Neurology, University of California, San Francisco, San Francisco, California S M, I K Department of Pediatrics, University of California, San Francisco, San Francisco, California S M, M D P, N G Brain Tumor Research Center, University of California, San Francisco Helen Diller Family Comprehensive Cancer Center, San Francisco, California S M, R H, X Y, A K O, J P, M W T, C D J, M S B, N G, D A H K Department of Neurological Surgery, University of California, San Francisco, San Francisco, California S M, J P, I S, M D P, C D J, M S B, N G, D A H K Department of Radiation Oncology, University of California, San Francisco, San Francisco, California D A H K
    Neuro Oncol 16:352-60. 2014
    ..We investigated the efficacy of the Wee1 inhibitor MK-1775 in combination with radiation for the treatment of pediatric high-grade gliomas (HGGs), including diffuse intrinsic pontine gliomas (DIPGs)...
  12. pmc The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression
    Kui Ming Chan
    Department of Biochemistry and Molecular Biology, University of California at San Francisco, San Francisco, California 94143, USA
    Genes Dev 27:985-90. 2013
    ..These results indicate that H3.3K27M mutation reprograms epigenetic landscape and gene expression, which may drive tumorigenesis...
  13. pmc PDGFRA amplification is common in pediatric and adult high-grade astrocytomas and identifies a poor prognostic group in IDH1 mutant glioblastoma
    Joanna J Phillips
    Department of Pathology, University of California San Francisco, San Francisco, CA, USA
    Brain Pathol 23:565-73. 2013
    ..To our knowledge, this is the largest survey of PDGFRA status in adult and pediatric HGAs and suggests PDGFRA amplification increases with grade and is associated with a less favorable prognosis in IDH1 mutant de novo GBMs. ..
  14. pmc PTEN promoter methylation and activation of the PI3K/Akt/mTOR pathway in pediatric gliomas and influence on clinical outcome
    Sabine Mueller
    Department of Pediatrics, University of California, San Francisco, CA, USA
    Neuro Oncol 14:1146-52. 2012
    ..0475). Tumors with no PTEN expression had a higher MIB labeling index (P= .007). The majority of pediatric gliomas show activation of the PI3K/Akt/mTOR pathway, with methylation of the PTEN promoter occurring commonly in these tumors...
  15. pmc Vorinostat increases expression of functional norepinephrine transporter in neuroblastoma in vitro and in vivo model systems
    Swati S More
    Departments of Bioengineering and Therapeutic Sciences, UCSF School of Medicine and UCSF Benioff Children s Hospital, San Francisco, California 94158, USA
    Clin Cancer Res 17:2339-49. 2011
    ....
  16. ncbi request reprint Neuroblastoma: biology and staging
    Sabine Mueller
    Department of Pediatric Hematology Oncology, University of California, San Francisco School of Medicine, M647, 505 Parnassus Avenue, San Francisco, CA 94143, USA
    Curr Oncol Rep 11:431-8. 2009
    ..This review discusses the biology of these tumors, current and new risk classification, and staging recommendations, with a brief outline of preferred treatment strategies...
  17. pmc The superiority of conservative resection and adjuvant radiation for craniopharyngiomas
    Adam Schoenfeld
    Department of Radiation Oncology, University of California, San Francisco UCSF, San Francisco, CA 94143 1708, USA
    J Neurooncol 108:133-9. 2012
    ..014). In conclusion, for patients with craniopharyngioma, STR + RT may provide superior clinical outcome, achieving better disease control than STR and limiting side effects associated with aggressive surgical resection...
  18. doi request reprint Multidisciplinary care of patients with brain tumors
    Tannie Huang
    Division of Hematology Oncology, Department of Pediatrics, University of California, San Francisco, San Francisco, CA 94143, USA
    Surg Oncol Clin N Am 22:161-78. 2013
    ..This article examines the roles of these subspecialists, with the goal of summarizing standard-of-care practices, recent therapeutic advances, and ongoing clinical investigations within each subspecialty...
  19. doi request reprint Characterization of a diffuse intrinsic pontine glioma cell line: implications for future investigations and treatment
    Rintaro Hashizume
    Department of Neurological Surgery, Brain Tumor Research Center, University of California San Francisco, San Francisco, CA 94143 0520, USA
    J Neurooncol 110:305-13. 2012
    ..The hTERT modified cells are tumorigenic in athymic rodents, and produce brainstem tumors that recapitulate the infiltrative growth of brainstem gliomas in patients...