Jan Moynihan

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. ncbi request reprint Chronic foot shock induces hyperactive behaviors and accompanying pro- and anti-inflammatory responses in mice
    Ling Cao
    Box PSYCH, Department of Psychiatry, University of Rochester, 300 Crittenden Blvd, Rochester, NY 14642, USA
    J Neuroimmunol 186:63-74. 2007
  2. pmc Brain behavior and immunity: twenty years of T cells
    Jan A Moynihan
    Rochester Center for Mind Body Research, Department of Psychiatry, University of Rochester Medical Center, Rochester, NY 14642, USA
    Brain Behav Immun 21:872-80. 2007
  3. ncbi request reprint Mechanisms of stress-induced modulation of immunity
    Jan A Moynihan
    Department of Psychiatry, University of Rochester Medical Center, The Center for Psychoneuroimmunology Research, 300 Crittenden Blvd, NY 14642, USA
    Brain Behav Immun 17:S11-6. 2003
  4. ncbi request reprint Sympathetic nervous system regulation of immunity
    Jan Moynihan
    The Center for Psychoneuroimmunology Research, University of Rochester Medical Center, 300 Crittenden Boulevard, Rochester, NY 14642, USA
    J Neuroimmunol 147:87-90. 2004
  5. ncbi request reprint Psychosocial factors and the response to influenza vaccination in older adults
    Jan A Moynihan
    Department of Psychiatry, University of Rochester Medical Center, Box PSYCH, 300 Crittenden Blvd, Rochester, NY 14642, USA
    Psychosom Med 66:950-3. 2004
  6. pmc Associations among depression, perceived self-efficacy, and immune function and health in preadolescent children
    Mary T Caserta
    University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
    Dev Psychopathol 23:1139-47. 2011
  7. pmc Big 5 personality traits and interleukin-6: evidence for "healthy Neuroticism" in a US population sample
    Nicholas A Turiano
    University of Rochester School of Medicine and Dentistry, Department of Psychiatry, Rochester, NY, United States
    Brain Behav Immun 28:83-9. 2013
  8. pmc Comparative effectiveness of CBT interventions for co-morbid chronic pain & insomnia: a pilot study
    Wilfred R Pigeon
    University of Rochester Medical Center, Department of Psychiatry, Rochester, NY, USA
    Behav Res Ther 50:685-9. 2012
  9. pmc Gender, race/ethnicity, personality, and interleukin-6 in urban primary care patients
    Benjamin P Chapman
    Department of Psychiatry, Rochester Center for Mind Body Research, University of Rochester Medical Center, Rochester, NY 14642, USA
    Brain Behav Immun 23:636-42. 2009
  10. ncbi request reprint Stress causes a further decrease in immunity to herpes simplex virus-1 in immunocompromised hosts
    Ling Cao
    Department of Psychiatry, The Center for Psychoneuroimmunology, University of Rochester, Rochester, NY 14642, USA
    J Neuroimmunol 156:21-30. 2004

Detail Information

Publications25

  1. ncbi request reprint Chronic foot shock induces hyperactive behaviors and accompanying pro- and anti-inflammatory responses in mice
    Ling Cao
    Box PSYCH, Department of Psychiatry, University of Rochester, 300 Crittenden Blvd, Rochester, NY 14642, USA
    J Neuroimmunol 186:63-74. 2007
    ..CMFS is associated with multiple dynamic immunological changes, suggesting involvement of multiple factors in chronic stress-induced behavioral changes...
  2. pmc Brain behavior and immunity: twenty years of T cells
    Jan A Moynihan
    Rochester Center for Mind Body Research, Department of Psychiatry, University of Rochester Medical Center, Rochester, NY 14642, USA
    Brain Behav Immun 21:872-80. 2007
    ....
  3. ncbi request reprint Mechanisms of stress-induced modulation of immunity
    Jan A Moynihan
    Department of Psychiatry, University of Rochester Medical Center, The Center for Psychoneuroimmunology Research, 300 Crittenden Blvd, NY 14642, USA
    Brain Behav Immun 17:S11-6. 2003
    ..The purpose of this chapter is to discuss the wealth of animal studies of stress-induced modulation of immunity, and to relate our understanding of stress and immunity to clinical populations, particularly cancer patients...
  4. ncbi request reprint Sympathetic nervous system regulation of immunity
    Jan Moynihan
    The Center for Psychoneuroimmunology Research, University of Rochester Medical Center, 300 Crittenden Boulevard, Rochester, NY 14642, USA
    J Neuroimmunol 147:87-90. 2004
  5. ncbi request reprint Psychosocial factors and the response to influenza vaccination in older adults
    Jan A Moynihan
    Department of Psychiatry, University of Rochester Medical Center, Box PSYCH, 300 Crittenden Blvd, Rochester, NY 14642, USA
    Psychosom Med 66:950-3. 2004
    ..We examined the influence of psychological state (depression, negative affect, perceived stress) and social support on pre- and post-vaccination response to influenza vaccine...
  6. pmc Associations among depression, perceived self-efficacy, and immune function and health in preadolescent children
    Mary T Caserta
    University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
    Dev Psychopathol 23:1139-47. 2011
    ..These results build on and expand research on the notion of allostatic load and develop a groundwork for developmental studies in this area...
  7. pmc Big 5 personality traits and interleukin-6: evidence for "healthy Neuroticism" in a US population sample
    Nicholas A Turiano
    University of Rochester School of Medicine and Dentistry, Department of Psychiatry, Rochester, NY, United States
    Brain Behav Immun 28:83-9. 2013
    ..Using personality to identify those at risk may lead to greater personalization in the prevention and remediation of chronic inflammation...
  8. pmc Comparative effectiveness of CBT interventions for co-morbid chronic pain & insomnia: a pilot study
    Wilfred R Pigeon
    University of Rochester Medical Center, Department of Psychiatry, Rochester, NY, USA
    Behav Res Ther 50:685-9. 2012
    ....
  9. pmc Gender, race/ethnicity, personality, and interleukin-6 in urban primary care patients
    Benjamin P Chapman
    Department of Psychiatry, Rochester Center for Mind Body Research, University of Rochester Medical Center, Rochester, NY 14642, USA
    Brain Behav Immun 23:636-42. 2009
    ..physical activity itself, and whether IL-6 levels may be reduced by boosting regular activity levels in demographic segments such as women and minorities who appear susceptible to greater inflammation...
  10. ncbi request reprint Stress causes a further decrease in immunity to herpes simplex virus-1 in immunocompromised hosts
    Ling Cao
    Department of Psychiatry, The Center for Psychoneuroimmunology, University of Rochester, Rochester, NY 14642, USA
    J Neuroimmunol 156:21-30. 2004
    ..Thus, stress levels of patients should be taken into consideration prior to clinical treatment with immunosuppressants...
  11. pmc Elevated sleep disturbance among blacks in an urban family medicine practice
    Wilfred R Pigeon
    Department of Psychiatry, Sleep and Neurophysiology Research Laboratory, University of Rochester Medical Center, Rochester, NY, USA
    J Am Board Fam Med 24:161-8. 2011
    ..Blacks experience a number of health disparities. Sleep disturbances contribute to poor health. This preliminary study explores whether a disparity in sleep disturbances exists among blacks compared with whites and others...
  12. pmc Multisystem physiological dysfunction is associated with depressive symptoms in a population-based sample of older adults
    Roni W Kobrosly
    Department of Community and Preventive Medicine, University of Rochester Medical Center, Rochester, NY, USA
    Int J Geriatr Psychiatry 28:718-27. 2013
    ..To evaluate the association between multisystem physiological dysfunction and depressive symptom severity in the US older adults...
  13. pmc Openness and conscientiousness predict 34-week patterns of Interleukin-6 in older persons
    Benjamin P Chapman
    Center for Mind Body Research, Department of Psychiatry, University of Rochester Medical Center, USA
    Brain Behav Immun 25:667-73. 2011
    ..Older adults lower in Conscientiousness and Openness constitute a target population for anti-inflammatory interventions. Openness and Conscientiousness predicts 32-week patterns of Interleukin-6 in older persons...
  14. ncbi request reprint Association of family stress with natural killer cell activity and the frequency of illnesses in children
    Peter A Wyman
    Department of Psychiatry, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Arch Pediatr Adolesc Med 161:228-34. 2007
    ..To examine prospective associations between chronic stress in the parent-child and family systems and subsequent rates of illnesses and the activity of natural killer (NK) cells in children...
  15. pmc Light therapy for seasonal affective disorder in a clinical office setting
    Michael R Privitera
    University of Rochester Medical Center, Rochester, NY 14642, USA
    J Psychiatr Pract 16:387-93. 2010
    ....
  16. pmc History of sudden unexpected loss is associated with elevated interleukin-6 and decreased insulin-like growth factor-1 in women in an urban primary care setting
    Banu Cankaya
    Rochester Center for Mind Body Research, Department of Psychiatry, University of Rochester Medical Center, Rochester, New York, USA
    Psychosom Med 71:914-9. 2009
    ..The sudden unexpected death of a loved one confers risk of morbidity and mortality, perhaps due to dysregulation in the immune/inflammatory and endocrine systems...
  17. pmc The associations between psychosocial stress and the frequency of illness, and innate and adaptive immune function in children
    Mary T Caserta
    Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Brain Behav Immun 22:933-40. 2008
    ....
  18. doi request reprint Psychoneuroimmunology
    Francisco Tausk
    Department of Dermatology, University of Rochester, Rochester, New York 14642, USA
    Dermatol Ther 21:22-31. 2008
    ..Chronic stress affects significantly the function of the immune system as well as modifies the evolution of a variety of skin diseases, as psychosocial interventions have proved to be effective in their therapy...
  19. ncbi request reprint Modulation of the innate immune response to HSV-1 following acute administration of morphine: role of hypothalamo-pituitary-adrenal axis
    Patricia A Sheridan
    Interdepartmental Program in Neuroscience, 575 Elmwood Ave, University of Rochester, Rochester, NY 14621, USA
    J Neuroimmunol 158:145-52. 2005
    ..The results suggest that a single exposure to morphine 4 h prior to infection can significantly alter innate immune responses to a viral pathogen, and that these effects are partially mediated by glucocorticoids...
  20. ncbi request reprint The effects of chemical sympathectomy on T-cell cytokine responses are not mediated by altered peritoneal exudate cell function or an inflammatory response
    Tracy A Callahan
    Graduate Program in Neuroscience, The Center for Psychoneuroimmunology Research, Rochester, New York 14642, USA
    Brain Behav Immun 16:33-45. 2002
    ..These experiments indicate that an inflammatory response is not likely to be responsible for sympathectomy-induced immune alterations, eliminating a potential confounding factor in interpreting sympathectomy studies...
  21. ncbi request reprint Age effects on macrophage function vary by tissue site, nature of stimulant, and exercise behavior
    Marian L Kohut
    Department of Health and Human Performance, Iowa State University, 235 Forker, Ames, IA 50011 1160, USA
    Exp Gerontol 39:1347-60. 2004
    ..Chronic moderate exercise tended to reverse age-associated changes in macrophage function in old mice...
  22. ncbi request reprint Contrasting pattern of cytokines in antigen- versus mitogen-stimulated splenocyte cultures from chemically denervated mice
    Tracy A Callahan
    The Graduate Program in Neuroscience, The Center for Psychoneuroimmunology Research, University of Rochester Medical Center, 300 Crittenden Blvd, Box PSYCH, Rochester, NY 14642, USA
    Brain Behav Immun 16:764-73. 2002
    ..These data directly address some apparent discrepancies in the literature, and highlight potential regulatory sites to be further investigated in pathways of neural-immune communication...
  23. ncbi request reprint Acute morphine exposure potentiates the development of HSV-1-induced encephalitis
    Daniel T Lioy
    Department of Microbiology and Immunology, 575 Elmwood Ave, University of Rochester, Rochester, NY 14621, United States
    J Neuroimmunol 172:9-17. 2006
    ..Acute morphine exposure was observed to potentiate the development of HSVE in HSV-1 infected mice. The present data implicate a potential role for the blood-brain barrier in the development of HSVE in morphine-treated mice...
  24. ncbi request reprint Inflammatory markers, depression, and cardiac disease
    Jeffrey M Lyness
    Am J Psychiatry 162:195; author reply 195. 2005
  25. ncbi request reprint Chemical sympathectomy has no effect on the severity of murine AIDS: murine AIDS alone depletes norepinephrine levels in infected spleen
    Sheila P Kelley
    Center for Psychoneuroimmunology Research, University of Rochester Medical Center, 300 Crittenden Boulevard, Rochester, New York 14642, USA
    Brain Behav Immun 16:118-39. 2002
    ..This finding has not been previously reported in mice with MAIDS and suggests that the viral infection itself produces a functional sympathectomy in the spleen, a target of that infection...

Research Grants22

  1. EFECTS OF STRESS IN IMMUNOCOMPROMISED HOSTS
    Jan Moynihan; Fiscal Year: 2003
    ..In turn, this will result in prolonged allograft survival. In contrast, the immunocompromised animal will have poorer immune responses to an opportunistic pathogen (HSV-1). ..
  2. Mindfulness Based Stress Reduction as an Adjunctive Treatment for Psoriasis
    Jan A Moynihan; Fiscal Year: 2010
    ....
  3. Immunoregulation by Endogenous Opioids
    Jan Moynihan; Fiscal Year: 2004
    ..Specific Aim 4: To determine if C57B1/6 mice, which do not have altered immune responses to KLH following stress odor exposure, have evidence of elevated endogenous opioids following odor exposure. ..
  4. The Rochester Center for Mind-Body Research
    Jan Moynihan; Fiscal Year: 2006
    ..By the end of the award period, we will be a mature, established Center with a submitted program project or Center grant application. ..
  5. Mindfulness to Improve Elders' Immune and Health Status
    Jan Moynihan; Fiscal Year: 2007
    ..The findings of this RCT will have implications for the conceptualization, refinement, and dissemination of psychosocial interventions aimed at slowing the rate of immunosenescence. ..
  6. The Rochester Center for Mind-Body Research
    Jan Moynihan; Fiscal Year: 2007
    ..All RCMBR investigators will be supported by the Administrative Core, the Biological and Behavioral Assessment Core, the Biostatistics Core, and the Training, Assessment, and Risk Management Core. ..
  7. Mindfulness Based Stress Reduction as an Adjunctive Treatment for Psoriasis
    Jan Moynihan; Fiscal Year: 2009
    ....
  8. SCIENCE PARTNERSHIPS FOR HANDS-ON LEARNING -PHASE II
    Jan Moynihan; Fiscal Year: 2003
    ..Teachers will have use of a "lending library" of science equipment and supplies to perform activities in their classrooms. ..
  9. SCIENCE PARTNERSHIPS FOR HANDS ON LEARNING
    Jan Moynihan; Fiscal Year: 2000
    ..Students will learn how to use current technology to gather information as well as to disseminate information that they have learned. ..