Research Topics
Species | Jan MoynihanSummaryAffiliation: University of Rochester Country: USA Publications
Research Grants
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Detail Information
Publications
Chronic foot shock induces hyperactive behaviors and accompanying pro- and anti-inflammatory responses in miceLing Cao
Box PSYCH, Department of Psychiatry, University of Rochester, 300 Crittenden Blvd, Rochester, NY 14642, USA
J Neuroimmunol 186:63-74. 2007..CMFS is associated with multiple dynamic immunological changes, suggesting involvement of multiple factors in chronic stress-induced behavioral changes...- Mechanisms of stress-induced modulation of immunityJan A Moynihan
Department of Psychiatry, University of Rochester Medical Center, The Center for Psychoneuroimmunology Research, 300 Crittenden Blvd, NY 14642, USA
Brain Behav Immun 17:S11-6. 2003..The purpose of this chapter is to discuss the wealth of animal studies of stress-induced modulation of immunity, and to relate our understanding of stress and immunity to clinical populations, particularly cancer patients... - Sympathetic nervous system regulation of immunityJan Moynihan
The Center for Psychoneuroimmunology Research, University of Rochester Medical Center, 300 Crittenden Boulevard, Rochester, NY 14642, USA
J Neuroimmunol 147:87-90. 2004 - Psychosocial factors and the response to influenza vaccination in older adultsJan A Moynihan
Department of Psychiatry, University of Rochester Medical Center, Box PSYCH, 300 Crittenden Blvd, Rochester, NY 14642, USA
Psychosom Med 66:950-3. 2004..We examined the influence of psychological state (depression, negative affect, perceived stress) and social support on pre- and post-vaccination response to influenza vaccine... 
Brain behavior and immunity: twenty years of T cellsJan A Moynihan
Rochester Center for Mind Body Research, Department of Psychiatry, University of Rochester Medical Center, Rochester, NY 14642, USA
Brain Behav Immun 21:872-80. 2007....- Associations among depression, perceived self-efficacy, and immune function and health in preadolescent childrenMary T Caserta
University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
Dev Psychopathol 23:1139-47. 2011..These results build on and expand research on the notion of allostatic load and develop a groundwork for developmental studies in this area... - Gender, race/ethnicity, personality, and interleukin-6 in urban primary care patientsBenjamin P Chapman
Department of Psychiatry, Rochester Center for Mind Body Research, University of Rochester Medical Center, Rochester, NY 14642, USA
Brain Behav Immun 23:636-42. 2009..physical activity itself, and whether IL-6 levels may be reduced by boosting regular activity levels in demographic segments such as women and minorities who appear susceptible to greater inflammation... - Stress causes a further decrease in immunity to herpes simplex virus-1 in immunocompromised hostsLing Cao
Department of Psychiatry, The Center for Psychoneuroimmunology, University of Rochester, Rochester, NY 14642, USA
J Neuroimmunol 156:21-30. 2004..Thus, stress levels of patients should be taken into consideration prior to clinical treatment with immunosuppressants... - Elevated sleep disturbance among blacks in an urban family medicine practiceWilfred R Pigeon
Department of Psychiatry, Sleep and Neurophysiology Research Laboratory, University of Rochester Medical Center, Rochester, NY, USA
J Am Board Fam Med 24:161-8. 2011..Blacks experience a number of health disparities. Sleep disturbances contribute to poor health. This preliminary study explores whether a disparity in sleep disturbances exists among blacks compared with whites and others... - Comparative effectiveness of CBT interventions for co-morbid chronic pain & insomnia: a pilot studyWilfred R Pigeon
University of Rochester Medical Center, Department of Psychiatry, Rochester, NY, USA
Behav Res Ther 50:685-9. 2012.... - Openness and conscientiousness predict 34-week patterns of Interleukin-6 in older personsBenjamin P Chapman
Center for Mind Body Research, Department of Psychiatry, University of Rochester Medical Center, USA
Brain Behav Immun 25:667-73. 2011..Older adults lower in Conscientiousness and Openness constitute a target population for anti-inflammatory interventions. Openness and Conscientiousness predicts 32-week patterns of Interleukin-6 in older persons... - Association of family stress with natural killer cell activity and the frequency of illnesses in childrenPeter A Wyman
Department of Psychiatry, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY 14642, USA
Arch Pediatr Adolesc Med 161:228-34. 2007..To examine prospective associations between chronic stress in the parent-child and family systems and subsequent rates of illnesses and the activity of natural killer (NK) cells in children... - Big 5 personality traits and interleukin-6: Evidence for "healthy Neuroticism" in a US population sampleNicholas A Turiano
University of Rochester School of Medicine and Dentistry, Department of Psychiatry, Rochester, NY, United States Center on Aging and the Life Course, West Lafayette, IN, United States Electronic address
Brain Behav Immun 28:83-9. 2013..Using personality to identify those at risk may lead to greater personalization in the prevention and remediation of chronic inflammation... - History of sudden unexpected loss is associated with elevated interleukin-6 and decreased insulin-like growth factor-1 in women in an urban primary care settingBanu Cankaya
Rochester Center for Mind Body Research, Department of Psychiatry, University of Rochester Medical Center, Rochester, New York, USA
Psychosom Med 71:914-9. 2009..The sudden unexpected death of a loved one confers risk of morbidity and mortality, perhaps due to dysregulation in the immune/inflammatory and endocrine systems... - Light therapy for seasonal affective disorder in a clinical office settingMichael R Privitera
University of Rochester Medical Center, Rochester, NY 14642, USA
J Psychiatr Pract 16:387-93. 2010.... - The associations between psychosocial stress and the frequency of illness, and innate and adaptive immune function in childrenMary T Caserta
Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Brain Behav Immun 22:933-40. 2008.... 
PsychoneuroimmunologyFrancisco Tausk
Department of Dermatology, University of Rochester, Rochester, New York 14642, USA
Dermatol Ther 21:22-31. 2008..Chronic stress affects significantly the function of the immune system as well as modifies the evolution of a variety of skin diseases, as psychosocial interventions have proved to be effective in their therapy...- Modulation of the innate immune response to HSV-1 following acute administration of morphine: role of hypothalamo-pituitary-adrenal axisPatricia A Sheridan
Interdepartmental Program in Neuroscience, 575 Elmwood Ave, University of Rochester, Rochester, NY 14621, USA
J Neuroimmunol 158:145-52. 2005..The results suggest that a single exposure to morphine 4 h prior to infection can significantly alter innate immune responses to a viral pathogen, and that these effects are partially mediated by glucocorticoids... - The effects of chemical sympathectomy on T-cell cytokine responses are not mediated by altered peritoneal exudate cell function or an inflammatory responseTracy A Callahan
Graduate Program in Neuroscience, The Center for Psychoneuroimmunology Research, Rochester, New York 14642, USA
Brain Behav Immun 16:33-45. 2002..These experiments indicate that an inflammatory response is not likely to be responsible for sympathectomy-induced immune alterations, eliminating a potential confounding factor in interpreting sympathectomy studies... - Age effects on macrophage function vary by tissue site, nature of stimulant, and exercise behaviorMarian L Kohut
Department of Health and Human Performance, Iowa State University, 235 Forker, Ames, IA 50011 1160, USA
Exp Gerontol 39:1347-60. 2004..Chronic moderate exercise tended to reverse age-associated changes in macrophage function in old mice... - Contrasting pattern of cytokines in antigen- versus mitogen-stimulated splenocyte cultures from chemically denervated miceTracy A Callahan
The Graduate Program in Neuroscience, The Center for Psychoneuroimmunology Research, University of Rochester Medical Center, 300 Crittenden Blvd, Box PSYCH, Rochester, NY 14642, USA
Brain Behav Immun 16:764-73. 2002..These data directly address some apparent discrepancies in the literature, and highlight potential regulatory sites to be further investigated in pathways of neural-immune communication... - Acute morphine exposure potentiates the development of HSV-1-induced encephalitisDaniel T Lioy
Department of Microbiology and Immunology, 575 Elmwood Ave, University of Rochester, Rochester, NY 14621, United States
J Neuroimmunol 172:9-17. 2006..Acute morphine exposure was observed to potentiate the development of HSVE in HSV-1 infected mice. The present data implicate a potential role for the blood-brain barrier in the development of HSVE in morphine-treated mice... - Inflammatory markers, depression, and cardiac diseaseJeffrey M Lyness
Am J Psychiatry 162:195; author reply 195. 2005 - Chemical sympathectomy has no effect on the severity of murine AIDS: murine AIDS alone depletes norepinephrine levels in infected spleenSheila P Kelley
Center for Psychoneuroimmunology Research, University of Rochester Medical Center, 300 Crittenden Boulevard, Rochester, New York 14642, USA
Brain Behav Immun 16:118-39. 2002..This finding has not been previously reported in mice with MAIDS and suggests that the viral infection itself produces a functional sympathectomy in the spleen, a target of that infection...
Research Grants
- EFECTS OF STRESS IN IMMUNOCOMPROMISED HOSTSJan Moynihan; Fiscal Year: 2003..In turn, this will result in prolonged allograft survival. In contrast, the immunocompromised animal will have poorer immune responses to an opportunistic pathogen (HSV-1). ..
- Mindfulness Based Stress Reduction as an Adjunctive Treatment for PsoriasisJan A Moynihan; Fiscal Year: 2010....
- Immunoregulation by Endogenous OpioidsJan Moynihan; Fiscal Year: 2004..Specific Aim 4: To determine if C57B1/6 mice, which do not have altered immune responses to KLH following stress odor exposure, have evidence of elevated endogenous opioids following odor exposure. ..
- The Rochester Center for Mind-Body ResearchJan Moynihan; Fiscal Year: 2006..By the end of the award period, we will be a mature, established Center with a submitted program project or Center grant application. ..
- Mindfulness to Improve Elders' Immune and Health StatusJan Moynihan; Fiscal Year: 2007..The findings of this RCT will have implications for the conceptualization, refinement, and dissemination of psychosocial interventions aimed at slowing the rate of immunosenescence. ..
- The Rochester Center for Mind-Body ResearchJan Moynihan; Fiscal Year: 2007..All RCMBR investigators will be supported by the Administrative Core, the Biological and Behavioral Assessment Core, the Biostatistics Core, and the Training, Assessment, and Risk Management Core. ..
- Mindfulness Based Stress Reduction as an Adjunctive Treatment for PsoriasisJan Moynihan; Fiscal Year: 2009....
- SCIENCE PARTNERSHIPS FOR HANDS-ON LEARNING -PHASE IIJan Moynihan; Fiscal Year: 2003..Teachers will have use of a "lending library" of science equipment and supplies to perform activities in their classrooms. ..
- SCIENCE PARTNERSHIPS FOR HANDS ON LEARNINGJan Moynihan; Fiscal Year: 2000..Students will learn how to use current technology to gather information as well as to disseminate information that they have learned. ..