Research Topics
Species | Sarosh J MotivalaSummaryAffiliation: University of California Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Sleep and inflammation: psychoneuroimmunology in the context of cardiovascular diseaseSarosh J Motivala
Cousins Center for Psychoneuroimmunology, UCLA Semel Institute, 300 Medical Plaza, Los Angeles, CA 90095 7057, USA
Ann Behav Med 42:141-52. 2011..Inflammatory processes may be an important biological mechanism linking poor sleep to cardiovascular disease. Such processes involve active participation of signaling molecules called cytokines in development of atherosclerotic plaques...
Leptin and cellular and innate immunity in abstinent alcoholics and controlsSarosh J Motivala
Cousin Center for Psychoneuroimmunology, University of California Los Angeles, Neuropsychiatric Institute, 90095 7076, USA
Alcohol Clin Exp Res 27:1819-24. 2003..Given evidence that concentrations of leptin are altered in alcoholics who also show immune abnormalities, this study examined the relationships between circulating levels of leptin and markers of cellular and innate immunity...- Inflammatory markers and sleep disturbance in major depressionSarosh J Motivala
Cousins Center for Psychoneuroimmunology, UCLA Neuropsychiatric Institute, University of California, Los Angeles, CA, USA
Psychosom Med 67:187-94. 2005..This study was conducted to determine whether immune activation occurs in major depression, and to evaluate the associations between disordered sleep and markers of inflammation in patients with major depressive disorder... 
Nocturnal levels of ghrelin and leptin and sleep in chronic insomniaSarosh J Motivala
University of California, Los Angeles Cousins Center for Psychoneuroimmunology, Los Angeles, CA 90095 7076, United States
Psychoneuroendocrinology 34:540-5. 2009..These findings suggest that insomnia patients have a dysregulation in energy balance that may play a role in explaining prospective weight gain in this population...- Stress activation of cellular markers of inflammation in rheumatoid arthritis: protective effects of tumor necrosis factor alpha antagonistsSarosh J Motivala
UCLA Semel Institute for Neuroscience and Human Behavior, Cousins Center for Psychoneuroimmunology, University of California, Los Angeles 90095 7076, USA
Arthritis Rheum 58:376-83. 2008..The purpose of this study was to determine whether RA patients show increased monocyte production of TNFalpha following acute psychological stress and whether such responses are abrogated in RA patients taking TNFalpha antagonists... - Tai Chi Chih acutely decreases sympathetic nervous system activity in older adultsSarosh J Motivala
Cousins Center for Psychoneuroimmunology, UCLA Semel Institute for Neuroscience and Human Behavior, 300 Medical Plaza, Suite 3148, Los Angeles, California 90095 7057, USA
J Gerontol A Biol Sci Med Sci 61:1177-80. 2006..The purpose of this study was to examine whether the practice of Tai Chi Chih (TCC), a movement-based relaxation practice, would acutely promote decreases of sympathetic activity in elderly persons... - Sex differences in monocyte expression of IL-6: role of autonomic mechanismsMary Frances O'Connor
Cousins Center for Psychoneuroimmunology, UCLA Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, 300 Medical Plaza, Los Angeles, CA 90095 7076, USA
Am J Physiol Regul Integr Comp Physiol 293:R145-51. 2007..Interventions that target autonomic mechanisms might constitute new strategies to constrain IL-6 production with impacts on inflammatory disease risk in women... - Impairments in health functioning and sleep quality in older adults with a history of depressionSarosh J Motivala
Department of Psychiatry and Biobehavioral Sciences, Cousins Center for Psychoneuroimmunology, University of California at Los Angeles, 90095, USA
J Am Geriatr Soc 54:1184-91. 2006..Moreover, in view of the association between sleep quality and health status, testing of interventions that target sleep quality might identify strategies to improve health functioning in older adults... - Cocaine dependence and acute cocaine induce decreases of monocyte proinflammatory cytokine expression across the diurnal period: autonomic mechanismsMichael R Irwin
Cousins Center for Psychoneuroimmunology, University of California, Los Angeles, CA 90095 7057, USA
J Pharmacol Exp Ther 320:507-15. 2007..Targeting sympathovagal balance might represent a novel strategy for partial amelioration of impairments of innate immunity in cocaine dependence... - Validation of a 3-factor scoring model for the Pittsburgh sleep quality index in older adultsJason C Cole
University of California, Cousins Center for Psychoneuroimmunology, Los Angeles, CA 90095-7076, USA
Sleep 29:112-6. 2006..CONCLUSIONS: These findings validate the factor structure of the PSQI and demonstrate that a 3-factor score should be used to assess disturbances in three separate factors of subjective sleep reports... - Improving sleep quality in older adults with moderate sleep complaints: A randomized controlled trial of Tai Chi ChihMichael R Irwin
University of California, Los Angeles, Cousins Center for Psychoneuroimmunology, Los Angeles, California, USA
Sleep 31:1001-8. 2008..To determine the efficacy of a novel behavioral intervention, Tai Chi Chih, to promote sleep quality in older adults with moderate sleep complaints... - Validation of single-factor structure and scoring protocol for the Health Assessment Questionnaire-Disability IndexJason C Cole
University of California, Los Angeles, CA, USA
Arthritis Rheum 53:536-42. 2005..In addition, the findings suggest some benefit from a secondary interpretation of the scores based on domains that measure motor skills... - Chronic stress and regulation of cellular markers of inflammation in rheumatoid arthritis: implications for fatigueMary C Davis
Department of Psychology, Arizona State University, P O Box 871104, Tempe, AZ 85287 1104, USA
Brain Behav Immun 22:24-32. 2008..The association between these markers of inflammation and fatigue was also tested... - Sympathoimmune anomalies underlying the response to stressful challenge in human immunodeficiency virus spectrum diseaseBarry E Hurwitz
Behavioral Medicine Research Center, University of Miami, Miami, Florida 33125, USA
Psychosom Med 67:798-806. 2005.... - Single-factor scoring validation for the Health Assessment Questionnaire-Disability Index (HAQ-DI) in patients with systemic sclerosis and comparison with early rheumatoid arthritis patientsJason C Cole
Consulting Measurement Group, Huntington Beach, CA 91403, USA
Qual Life Res 15:1383-94. 2006..The goal of the current study was to examine the structural validity of the HAQ-DI in patients with systemic sclerosis (SSc, scleroderma) and to compare its performance with that in patients with RA... - Psychological distress is associated with decreased memory helper T-cell and B-cell counts in pre-AIDS HIV seropositive men and women but only in those with low viral loadSarosh J Motivala
Behavioral Medicine Research Center, University of Miami, Miami, Florida 33125, USA
Psychosom Med 65:627-35. 2003..The lack of association in those persons with high viral load suggests that, even before AIDS onset, disease-related processes are disrupting CNS and immune system communication...
Research Grants
- Aging: Insomnia Treatment and Energy BalanceSarosh Motivala; Fiscal Year: 2007....