Research Topics
Species | Eydie L Moses-KolkoSummaryAffiliation: University of Pittsburgh Country: USA Publications
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Publications
Postpartum and depression status are associated with lower [[¹¹C]raclopride BP(ND) in reproductive-age womenEydie L Moses-Kolko
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Neuropsychopharmacology 37:1422-32. 2012....
Age, sex, and reproductive hormone effects on brain serotonin-1A and serotonin-2A receptor binding in a healthy populationEydie L Moses-Kolko
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Neuropsychopharmacology 36:2729-40. 2011..Additional study in clinical populations is needed to further examine the affective role of sex-hormone-serotonin receptor relationships...
Abnormally reduced dorsomedial prefrontal cortical activity and effective connectivity with amygdala in response to negative emotional faces in postpartum depressionEydie L Moses-Kolko
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Am J Psychiatry 167:1373-80. 2010..The authors examined activity in response to negative emotional faces in the dorsomedial pre-frontal cortex and amygdala, key emotion regulatory neural regions of importance to both mothering and depression...
Neonatal signs after late in utero exposure to serotonin reuptake inhibitors: literature review and implications for clinical applicationsEydie L Moses-Kolko
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
JAMA 293:2372-83. 2005..Integration of data about the neonatal behavioral syndrome into the management of pregnancy in women who take SRIs is a current challenge for physicians...
Rapid habituation of ventral striatal response to reward receipt in postpartum depressionEydie L Moses-Kolko
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
Biol Psychiatry 70:395-9. 2011..Previous research notes ventral striatal activity and dopamine release increases with maternal attachment but decreases in major depressive disorder. This study tests the hypothesis that striatal response to reward is altered in PPD...
Transdermal estradiol for postpartum depression: a promising treatment optionEydie L Moses-Kolko
Department of Psychiatry, Women s Behavioral HealthCARE, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
Clin Obstet Gynecol 52:516-29. 2009....
Measurement of 5-HT1A receptor binding in depressed adults before and after antidepressant drug treatment using positron emission tomography and [11C]WAY-100635Eydie L Moses-Kolko
Departments of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Synapse 61:523-30. 2007..To assess effects of chronic antidepressant drug treatment on serotonin type-1A receptor (5-HT(1A)R) binding potential (BP) in major depressive disorder...
Serotonin 1A receptor reductions in postpartum depression: a positron emission tomography studyEydie L Moses-Kolko
Department of Psychiatry, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania, USA
Fertil Steril 89:685-92. 2008..To measure brain serotonin-1A (5HT1A) receptor binding potential (BP) in healthy and depressed postpartum women...
Medial prefrontal cortex 5-HT(2A) density is correlated with amygdala reactivity, response habituation, and functional couplingPatrick M Fisher
Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA 15213, USA
Cereb Cortex 19:2499-507. 2009..Collectively, our results indicate that mPFC 5-HT(2A) is strongly associated with threat-related amygdala reactivity as well as its temporal habituation and functional coupling with prefrontal regulatory regions...
Medial prefrontal cortex serotonin 1A and 2A receptor binding interacts to predict threat-related amygdala reactivityPatrick M Fisher
Center for Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
Biol Mood Anxiety Disord 1:2. 2011..abstract:..
Major depression and antidepressant treatment: impact on pregnancy and neonatal outcomesKatherine L Wisner
Women s Behavioral HealthCARE and the Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, 3811 O Hara St, Pittsburgh, PA 15213, USA
Am J Psychiatry 166:557-66. 2009..This study examined whether 1) minor physical anomalies, 2) maternal weight gain and infant birth weight, 3) preterm birth, and 4) neonatal adaptation are affected by SSRI or depression exposure...
Widespread increases of cortical serotonin type 2A receptor availability after hormone therapy in euthymic postmenopausal womenEydie L Moses-Kolko
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Fertil Steril 80:554-9. 2003..To use statistical parametric mapping to determine the extent of previously reported serotonin type 2A (5HT(2A)) receptor binding potential (BP) increases in postmenopausal women following hormone therapy...
Postpartum depression: a randomized trial of sertraline versus nortriptylineKatherine L Wisner
Department of Obstetrics and Gynecology and Reproductive Sciences, Epidemiology and Women s Studies, Western Psychiatric Institute and Clinic University of Pittsburgh Medical Center, 3811 O Hara Street, Pittsburgh, PA 15213, USA
J Clin Psychopharmacol 26:353-60. 2006..Women who were responders and remitters at week 8 could be identified earlier if they were treated with SERT than with NTP. Breast-fed infant serum levels were near or below the level of quantifiability for both agents...
Antepartum and postpartum depression: healthy mom, healthy babyEydie L Moses-Kolko
University of Pittsburgh School of Medicine, USA
J Am Med Womens Assoc 59:181-91. 2004..Rapid and effective mental health intervention in depressed expectant or new mothers not only restores maternal function, but can also prevent adverse infant neurobehavioral outcomes...
No interruption of lactation is needed after (11)C-WAY 100635 or (11)C-raclopride PETEydie L Moses-Kolko
J Nucl Med 46:1765. 2005
Estradiol effects on the postmenopausal brainEydie L Moses-Kolko
Am J Psychiatry 161:2136; author reply 2136. 2004
Serotonin-1A receptor imaging in recurrent depression: replication and literature reviewWayne C Drevets
Mood and Anxiety Disorders Program, MINH Molecular Imaging Branch, Bethesda, MD 20892, USA
Nucl Med Biol 34:865-77. 2007..In the current study, we attempted to replicate our previous findings in an independent sample of subjects selected according to the criteria for primary recurrent depression applied in our prior study...
Research Grants
- Elucidating the Neurobiology of Postpartum DepressionEydie Moses Kolko; Fiscal Year: 2006..abstract_text> ..
- Serotonin-1A receptors in postpartum depressionEydie Moses Kolko; Fiscal Year: 2007..Results of this study will inform future studies of novel hormonal and behavioral treatments for postpartum depression. ..
