D J Moser

..Cerebrovascular reserve was additionally associated with performance on measures of memory and attention. Additional research is needed to determine whether measures of cerebral blood flow can be used to predict cognitive decline...

..This study was conducted to determine whether neuropsychological dysfunction associated with anorexia nervosa resolves with inpatient treatment...

..This study was conducted to determine the relationship between blood vessel function and cognition in elderly patients with atherosclerosis...

..The authors' goal was to determine whether people with schizophrenia experience changes in decisional capacity when their antipsychotic regimens are discontinued for research purposes...

..With additional research, measures of vascular function might become useful in the early identification of those individuals at greatest risk for vascular-related cognitive dysfunction...

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..The use of such interventions will enable a larger number of people with schizophrenia to make informed decisions regarding research participation...

..The current study was conducted to confirm and extend those findings in a much larger, nonoverlapping sample...

..However, when precise ME counts are required, bilateral monitoring is essential...

..To determine the relation between subcortical hyperintensities (SHs) visible on magnetic resonance imaging and executive function among patients with vascular dementia...

..These findings may have implications for treatment interventions that seek to enhance functioning in the skilled nursing setting...

..The objective of this study was to describe the relationship among cognitive test performance, psychological symptoms, and subjective cognitive difficulties in older adults with atherosclerotic vascular disease...

..Future studies will benefit also from examining the association between awareness and cognition in larger samples...

..Depression level and body mass were not associated with cognitive impairment. Whether effective restoration of weight and resolution of core psychopathology contribute to reversal of cognitive deficits requires further research...

..Despite serious past incidents, ethicists will need to consider the possibility that prisoners have become an overprotected population...

..These results are indicative of qualitative differences in the pattern of cognitive deficits associated with the two types of dementia...

..14). Neuropsychological testing demonstrated trends favoring drug treatment on measures of immediate recall and verbal fluency. While bupropion SR may be a viable clinical alternative for adults with ADHD, further investigation is needed...

..Education about these possible pretransplant sequelae and the potential for rebound may be helpful to patients and families as they prepare for this treatment and the recovery period...

..Additionally, this prognostic index could be used to offer interventions to patients who are in the earliest stages of progressive neurodegenerative disorders...

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..Practice effects have been widely reported in healthy older adults, but these improvements due to repeat exposure to test materials have been more equivocal in individuals with mild cognitive impairment (MCI)...

..The purpose of this study was to examine the predictive variance of neuropsychological and personality characteristics in PG...

..Preliminary data on poststroke depression suggest that repetitive transcranial magnetic stimulation (rTMS) might also be effective among patients with VD...

..Early in the course of HD, the cortex shows changes that are manifest as cortical thinning and are most robust in the posterior and superior regions of the cerebrum...

..This study compares self-paced timing performance (cross-sectionally and longitudinally) between participants with prodromal Huntington's disease (pr-HD) and a comparison group of gene non-expanded participants from affected families (NC)...

..Information about cognitive reserve and AN subtype may provide clinicians with valuable prognostic information and help guide treatment...

..64 and 0.66). Preliminary psychometric analyses support further study of the IFIPT. The measure showed evidence of clinical utility by demonstrating group differences between this sample of healthy adults and those with MCI...

..The objective was to examine cortical volumes in relation to cognitive performance among patients who do not have dementia, but who do have mild cognitive deficits...

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..Although psychiatric symptoms have been reported in individuals with the HD gene expansion prior to clinical diagnosis (pre-HD), little is known about OCS in this phase of disease...

..These data might allow clinicians and researchers to better assess laterality effects of brain dysfunction when using the RBANS, although clinical validation is needed...

..Poststroke depression has been shown in numerous studies to be associated with both impaired recovery in activities of daily living and increased mortality. Prevention of depression thus represents a potentially important goal...

..This study was undertaken to explore the mechanisms underlying cognitive reserve in subjects with mild memory deficits by using positron emission tomography (PET)...

..These findings support the possibility that the sexual dimorphism in the structure of the parietal lobe is a neurobiological substrate for the sex difference in performance on the mental rotations test...

..When diagnostic outcomes were discordant for free recall measures, the CVLT indicated impairment more often than did the WLT...

..The influence of psychiatric symptoms and cognitive impairment on daily living skills was explored in a series of nursing home residents. Three categories of symptoms were examined: behavioral disturbances, depression, and delusions...

..This study investigated the relationships between duration of untreated initial psychosis and neurocognitive functioning and high-resolution imaging brain measurements...

..The role of these differences in intensity of induced emotion and impairment in executive function in daily social and vocational activity should be investigated...

..It is unclear whether these deficits are linked to co-morbid depression in this population. We examined the relationship between depressive symptoms and cognitive functioning...

..Fewer studies have examined other cerebral structures in early HD and potential associations with cognition...

..The findings point towards circumscribed domains of impaired social cognition in schizophrenia and suggest specific further hypotheses about the neural dysfunction that may underlie them...

..That WBV emerged as a stronger correlate of dementia raises further questions regarding the cerebral mechanisms that contribute to the development of VaD...

..Between end-of-treatment at 3 months and follow-up at 2 years, significant correlation was found between improvement in executive function and decrease in denial of illness...

..Executive dysfunction is common after stroke and may impair long-term outcome. Remedies for this condition are limited...

..Findings supported the validity of noncredibility judgments and suggested that noncredible examinations are not a significant problem in neuropsychological investigations of GWVs...

..Patients in the active rTMS group improved significantly on a test of cognitive flexibility and conceptual tracking (Trail Making Test-B)...

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..If depression accompanies aggression, the results of this small study suggest that successful treatment of depression may reduce aggressive behavior...

..The Dementia Rating Scale (DRS) is a common measure of cognitive function, but its sensitivity to identify deficits across cognitive domains in vascular dementia (VaD) remains unclear...

..These findings highlight the importance of apathy as an independent factor associated with functional independence beyond general cognitive abilities...

..Intraoperative microemboli counts were not significantly associated with postsurgical neuropsychological functioning in either the CABG or VR group...

..To characterize cognition in patients with moderate to severe heart failure and examine the association between 2 measures of systemic perfusion (ie, ejection fraction and cardiac index) and cognition...

..This randomized, double-blind clinical trial was conducted to determine whether daily citicoline treatment improves neurocognitive and neuroimaging outcome over 12 months among patients diagnosed with vascular dementia (VaD)...

..To assess decisional capacity performance and the neuropsychological correlates of such performance to better understand higher-level instrumental activities of daily living in individuals with mild cognitive impairment (MCI)...

..The results demonstrate that the GTRACT algorithm is less sensitive to image noise and more capable of handling areas of complex fiber crossing, compared to conventional streamline methods...

..Further research is needed to determine whether this observed decline is attributable to differential lesion distribution or statistical artifact...

..These findings demonstrate that baseline executive dysfunction is a significant and powerful predictor of future functional decline in individuals with VaD...

..e., psychomotor speed, executive functioning) while the visual rating scale was not. Results suggest that this computer-mediated thresholding technique is superior to visual ratings of WMHs...

..These preliminary data suggest that retention rates of the RBANS memory subtests may add to the clinical utility of this test as a neuropsychological diagnostic and research tool...

..We investigated the stability of neuropsychological performance and eating disorder (EDO) symptoms before, immediately after, and 2 years after inpatient treatment. We also examined relationships between neuropsychological and EDO measures...

..The current findings suggest that poor cognitive flexibility and verbal retrieval in the context of preserved function in other domains may characterize the prodromal stage of VaD...

..This study examined changes in cognitive-functional relationships in vascular dementia (VaD) over the course of one year...

..To determine whether demographic data, dementia severity, functional status, whole brain volume (WBV), or subcortical hyperintensity volume (SH) predict subsequent cognitive decline in vascular dementia (VaD)...

..Further, the GDS score accurately classified 87% of the patients with VaD. These findings provide support for the validity of the GDS in general staging of dementia severity of VaD...

..However, in this sample we did not detect a significant association between phobic anxiety and the 5HTTLPR genotype. The interaction between age-related changes in cognition and anxiety remain an important area for future studies...

..The proposed research is expected to yield publishable results and will also provide valuable pilot data for larger scale (e.g. R01) grant applications. ..

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..Molecular epidemiologic methods will trace the origin of resistant strains in NHs and further characterize newer hyper-virulent strains of MRSA emerging in this often neglected setting. ..

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