Anna Barbara Moscicki

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Redetection of cervical human papillomavirus type 16 (HPV16) in women with a history of HPV16
    Anna Barbara Moscicki
    Department of Pediatrics, University of California, San Francisco, CA, USA
    J Infect Dis 208:403-12. 2013
  2. doi request reprint Immune responses elicited by a fourth dose of the HPV-16/18 AS04-adjuvanted vaccine in previously vaccinated adult women
    A B Moscicki
    University of California, Division of Adolescent Medicine, San Franscico, CA 94118, USA
    Vaccine 31:234-41. 2012
  3. pmc Updating the natural history of human papillomavirus and anogenital cancers
    Anna Barbara Moscicki
    Division of Adolescent Medicine, Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA
    Vaccine 30:F24-33. 2012
  4. pmc Measurement of mucosal biomarkers in a phase 1 trial of intravaginal 3% StarPharma LTD 7013 gel (VivaGel) to assess expanded safety
    Anna Barbara Moscicki
    Department of Pediatrics, University of California, San Francisco, CA 94118, USA
    J Acquir Immune Defic Syndr 59:134-40. 2012
  5. pmc The role of sexual behavior and human papillomavirus persistence in predicting repeated infections with new human papillomavirus types
    Anna Barbara Moscicki
    Division of Adolescent Medicine, Department of Pediatrics, University of California San Francisco, 3333 California Street, San Francisco, CA 94118, USA
    Cancer Epidemiol Biomarkers Prev 19:2055-65. 2010
  6. pmc Human papillomavirus disease and vaccines in adolescents
    Anna Barbara Moscicki
    Division of Adolescent Medicine, University of California San Francisco, 3333 California Street, San Francisco, CA 94118, USA
    Adolesc Med State Art Rev 21:347-63, x-xi. 2010
  7. pmc Comparison of natural histories of human papillomavirus detected by clinician- and self-sampling
    Anna Barbara Moscicki
    Department of Pediatrics, Division of Adolescent Medicine, University of California, San Francisco, CA 94118, USA
    Int J Cancer 127:1882-92. 2010
  8. pmc HPV Vaccines: today and in the Future
    Anna Barbara Moscicki
    Division of Adolescent Medicine, University of California, San Francisco, San Francisco, California 94118, USA
    J Adolesc Health 43:S26-40. 2008
  9. ncbi request reprint Vaginal microbicides: where are we and where are we going?
    Anna Barbara Moscicki
    Division of Adolescent Medicine, Department of Pediatrics, University of California San Francisco, 3333 California Street, Suite 245, San Francisco, CA 94118, USA
    J Infect Chemother 14:337-41. 2008
  10. pmc Conservative management of adolescents with abnormal cytology and histology
    Anna Barbara Moscicki
    Division of Adolescent Medicine, University of California San Francisco, 3333 California Street, Suite 245, San Francisco, CA 94118, USA
    J Natl Compr Canc Netw 6:101-6. 2008

Research Grants

  1. Natural History of CIN2 in Adolescents
    Anna Barbara Moscicki; Fiscal Year: 2001
  2. NATURAL HISTORY OF HPV--INFECTION TO NEOPLASIA
    Anna Barbara Moscicki; Fiscal Year: 2001
  3. Natural History of CIN2 in Adolescents
    Anna Barbara Moscicki; Fiscal Year: 2002
  4. NATURAL HISTORY OF HPV--INFECTION TO NEOPLASIA
    Anna Barbara Moscicki; Fiscal Year: 2002
  5. Natural History of CIN2 in Adolescents
    Anna Barbara Moscicki; Fiscal Year: 2003
  6. NATURAL HISTORY OF HPV--INFECTION TO NEOPLASIA
    Anna Barbara Moscicki; Fiscal Year: 2003
  7. Natural History of CIN2 in Adolescents
    Anna Barbara Moscicki; Fiscal Year: 2004
  8. NATURAL HISTORY OF HPV--INFECTION TO NEOPLASIA
    Anna Barbara Moscicki; Fiscal Year: 2004
  9. Natural History of CIN2 in Adolescents
    Anna Barbara Moscicki; Fiscal Year: 2005
  10. A San Francisco Street Youth Cohort: At Risk and HIV+
    Anna Barbara Moscicki; Fiscal Year: 2007

Detail Information

Publications78

  1. pmc Redetection of cervical human papillomavirus type 16 (HPV16) in women with a history of HPV16
    Anna Barbara Moscicki
    Department of Pediatrics, University of California, San Francisco, CA, USA
    J Infect Dis 208:403-12. 2013
    ..The purpose of this study was to examine the rate of and risks for cervical human papillomavirus type 16 (HPV16) redetection in women with documented or suspected HPV16 infection...
  2. doi request reprint Immune responses elicited by a fourth dose of the HPV-16/18 AS04-adjuvanted vaccine in previously vaccinated adult women
    A B Moscicki
    University of California, Division of Adolescent Medicine, San Franscico, CA 94118, USA
    Vaccine 31:234-41. 2012
    ..The current study, HPV-024 (NCT00546078, http://clinicaltrials.gov), assessed the immune memory in North American women who received three doses of HPV-16/18 AS04-adjuvanted vaccine 7 years earlier in HPV-001 (NCT00689741)...
  3. pmc Updating the natural history of human papillomavirus and anogenital cancers
    Anna Barbara Moscicki
    Division of Adolescent Medicine, Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA
    Vaccine 30:F24-33. 2012
    ..This article forms part of a special supplement entitled "Comprehensive Control of HPV Infections and Related Diseases" Vaccine Volume 30, Supplement 5, 2012...
  4. pmc Measurement of mucosal biomarkers in a phase 1 trial of intravaginal 3% StarPharma LTD 7013 gel (VivaGel) to assess expanded safety
    Anna Barbara Moscicki
    Department of Pediatrics, University of California, San Francisco, CA 94118, USA
    J Acquir Immune Defic Syndr 59:134-40. 2012
    ..The aim of this study was to examine the effect of the 3% StarPharma LTD 7013 gel (VivaGel) on mucosal immune markers hypothesized to be associated with HIV-1 acquisition...
  5. pmc The role of sexual behavior and human papillomavirus persistence in predicting repeated infections with new human papillomavirus types
    Anna Barbara Moscicki
    Division of Adolescent Medicine, Department of Pediatrics, University of California San Francisco, 3333 California Street, San Francisco, CA 94118, USA
    Cancer Epidemiol Biomarkers Prev 19:2055-65. 2010
    ..Although human papillomavirus (HPV) infections are common in young women, the rate of and risk for repeated new infections are not well documented. We examined the rate of and risks for new HPV detection in young women...
  6. pmc Human papillomavirus disease and vaccines in adolescents
    Anna Barbara Moscicki
    Division of Adolescent Medicine, University of California San Francisco, 3333 California Street, San Francisco, CA 94118, USA
    Adolesc Med State Art Rev 21:347-63, x-xi. 2010
    ..In this chapter, we cover the advances in science that have led to new screening recommendation for cervical cancer and the advances in prevention: vaccines for both adolescent women and men...
  7. pmc Comparison of natural histories of human papillomavirus detected by clinician- and self-sampling
    Anna Barbara Moscicki
    Department of Pediatrics, Division of Adolescent Medicine, University of California, San Francisco, CA 94118, USA
    Int J Cancer 127:1882-92. 2010
    ..Our findings suggest using SC vaginal swabs would observe similar natural histories of HPV compared to studies using CC-L specimens making self-testing feasible for repeated HPV DNA detection...
  8. pmc HPV Vaccines: today and in the Future
    Anna Barbara Moscicki
    Division of Adolescent Medicine, University of California, San Francisco, San Francisco, California 94118, USA
    J Adolesc Health 43:S26-40. 2008
    ..The article also discusses the safety and efficacy of commercially available prophylactic vaccines against HPV, as well as novel prophylactic and therapeutic vaccine delivery strategies in early clinical development...
  9. ncbi request reprint Vaginal microbicides: where are we and where are we going?
    Anna Barbara Moscicki
    Division of Adolescent Medicine, Department of Pediatrics, University of California San Francisco, 3333 California Street, Suite 245, San Francisco, CA 94118, USA
    J Infect Chemother 14:337-41. 2008
    ..Even with a good product, acceptance by both partners will be essential for its success, and lack of acceptance is often not evident until large trials are completed...
  10. pmc Conservative management of adolescents with abnormal cytology and histology
    Anna Barbara Moscicki
    Division of Adolescent Medicine, University of California San Francisco, 3333 California Street, Suite 245, San Francisco, CA 94118, USA
    J Natl Compr Canc Netw 6:101-6. 2008
    ..CIN II in adherent adolescents can be managed with 6-month cytology and colposcopy...
  11. pmc HPV infections in adolescents
    Anna Barbara Moscicki
    Division of Adolescent Medicine, University of California, San Francisco, CA 94118, USA
    Dis Markers 23:229-34. 2007
    ..In addition, with the advent of the HPV vaccine, vaccination prior to the onset of sexual activity is critical since most infections occur within a short time frame post initiation...
  12. pmc Rate of and risks for regression of cervical intraepithelial neoplasia 2 in adolescents and young women
    Anna Barbara Moscicki
    Department of Pediatrics, School of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA
    Obstet Gynecol 116:1373-80. 2010
    ..To describe the natural history of cervical intraepithelial neoplasia (CIN) 2 in a prospective study of adolescents and young women, and to examine the behavioral and biologic factors associated with regression and progression...
  13. pmc Risks for cervical intraepithelial neoplasia 3 among adolescents and young women with abnormal cytology
    Anna Barbara Moscicki
    Department of Pediatrics, School of Medicine, University of California, San Francisco, California 94143, USA
    Obstet Gynecol 112:1335-42. 2008
    ..To estimate the risks of cervical intraepithelial neoplasia (CIN) 3 among girls and women aged 13 to 24 years who were referred for abnormal cytology while receiving care in a large health maintenance organization...
  14. pmc Management of adolescents who have abnormal cytology and histology
    Anna Barbara Moscicki
    Division of Adolescent Medicine, University of California San Francisco, 3333 California Street, Suite 245, San Francisco, CA 94118, USA
    Obstet Gynecol Clin North Am 35:633-43; x. 2008
    ..CIN 2,3 in compliant adolescents can be managed with 6-month cytology and colposcopy up to 2 years...
  15. ncbi request reprint Chapter 5: Updating the natural history of HPV and anogenital cancer
    Anna Barbara Moscicki
    Department of Pediatrics, Division of Adolescent Medicine, University of California San Francisco, 3333 California Avenue, San Francisco, CA, USA
    Vaccine 24:S3/42-51. 2006
    ..Finally, data on non-cervical HPV infections, such as penile infections are limited to date compared to cervical infections. Several ongoing cohort studies should give us further insight into male infections in the near future...
  16. pmc Type-specific cervico-vaginal human papillomavirus infection increases risk of HIV acquisition independent of other sexually transmitted infections
    Karen K Smith-McCune
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 5:e10094. 2010
    ..The objective of this study was to determine whether cervico-vaginal HPV infection increases the risk of HIV acquisition in women independent of other common STIs...
  17. pmc Time course of humoral and cell-mediated immune responses to human papillomavirus type 16 in infected women
    Mayumi Nakagawa
    Departments of Laboratory Medicine, Schools of Medicine and Dentistry, University of California at San Francisco, San Francisco, California 94143 0134, USA
    Clin Diagn Lab Immunol 9:877-82. 2002
    ..Overall, seven of eight subjects (88%) had detectable HPV-16 E6 and/or E7 CTL responses and seven of eight women (88%) had detectable HPV-16 VLP antibody responses...
  18. ncbi request reprint Human papillomavirus infection and abnormal cytology of the anus in HIV-infected and uninfected adolescents
    Anna Barbara Moscicki
    Department of Pediatrics, University of California San Francisco, 3333 California Street, Suite 245, San Francisco, CA 94118 0503, USA
    AIDS 17:311-20. 2003
    ..To examine the prevalence of and risk for anal human papillomavirus (HPV) infection and abnormal anal cytology in sexually active adolescents...
  19. ncbi request reprint Covariates of cervical cytokine mRNA expression by real-time PCR in adolescents and young women: effects of Chlamydia trachomatis infection, hormonal contraception, and smoking
    Mark E Scott
    Department of Pediatrics, Division of Adolescent Medicine, University of California, San Francisco, California 94143 1374, USA
    J Clin Immunol 26:222-32. 2006
    ..Time since last menstrual period did not affect any of the cytokines; in a substudy of weekly cytokine variability, however, IL-10 showed a non-significant trend toward higher levels around the time of menstruation...
  20. ncbi request reprint Persistence of human papillomavirus infection in HIV-infected and -uninfected adolescent girls: risk factors and differences, by phylogenetic type
    Anna Barbara Moscicki
    Department of Pediatrics, University of California, San Francisco 94118 0503, USA
    J Infect Dis 190:37-45. 2004
    ..The objective of this study was to examine the rates of and risk factors for persistence of HPV types among HIV-infected and -uninfected adolescent girls...
  21. pmc Active squamous metaplasia of the cervical epithelium is associated with subsequent acquisition of human papillomavirus 16 infection among healthy young women
    Loris Y Hwang
    University of California San Francisco, Department of Pediatrics, Division of Adolescent Medicine, 3333 California Street, Suite 245, San Francisco, CA 94118, USA
    J Infect Dis 206:504-11. 2012
    ..However, squamous metaplastic tissue may be more influential. We examined the extent of ectopy and metaplastic activity as risks for HPV16 acquisition in a prospective cohort...
  22. ncbi request reprint Effect of Replens gel used with a diaphragm on tests for human papillomavirus and other lower genital tract infections
    Karen K Smith-McCune
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Francisco, San Francisco, CA 94143 0128, USA
    J Low Genit Tract Dis 10:213-8. 2006
    ..We hypothesized that Replens gel used with a diaphragm would neither inhibit human papillomavirus (HPV) detection in cervical samples and chlamydia (CT) and gonorrhea (GC) detection in urine samples, nor affect cervical cytology quality...
  23. pmc Human papillomavirus infections in nonsexually active perinatally HIV infected children
    Anna Barbara Moscicki
    1 Division of Adolescent Medicine, Department of Pediatrics, University of California San Francisco, San Francisco, California
    AIDS Patient Care STDS 28:66-70. 2014
    ..07). This large age gap precluded statistical comparison by HIV status. The presence of HPV in NSA PHIV+ children may have implications regarding HPV vaccination efficacy...
  24. pmc Natural history of anal human papillomavirus infection in heterosexual women and risks associated with persistence
    Anna Barbara Moscicki
    Division of Adolescent Medicine, Department of Pediatrics
    Clin Infect Dis 58:804-11. 2014
    ..Specific sexual behaviors were associated with persistence, suggesting that education and behavioral interventions may decrease persistence. ..
  25. pmc Cervical ectopy and the acquisition of human papillomavirus in adolescents and young women
    Loris Y Hwang
    Department of Pediatrics, University of California, San Francisco, CA, USA
    Obstet Gynecol 119:1164-70. 2012
    ..Our objective was to estimate associations between ectopy and incident HPV in healthy adolescents and young women...
  26. pmc Higher levels of cervicovaginal inflammatory and regulatory cytokines and chemokines in healthy young women with immature cervical epithelium
    Loris Y Hwang
    University of California San Francisco, Department of Pediatrics, Division of Adolescent Medicine, 3333 California Street, Suite 245, San Francisco, CA 94118, USA
    J Reprod Immunol 88:66-71. 2011
    ..Cytokine profiles in the healthy state may foreshadow differential responses to pathogens. Cervical epithelial type should be measured in clinical studies involving cervicovaginal immune markers...
  27. ncbi request reprint Regression of low-grade squamous intra-epithelial lesions in young women
    Anna Barbara Moscicki
    Department of Pediatrics, University of California, San Francisco, CA, USA
    Lancet 364:1678-83. 2004
    ..The aim of this study was to assess the probability of low-grade squamous intra-epithelial lesion (LSIL) regression in young women, and to examine the factors associated with this regression...
  28. ncbi request reprint Utility of cervicography in HIV-infected and uninfected adolescents
    Anna Barbara Moscicki
    Department of Pediatrics, University of California, San Francisco, San Francisco, California, USA
    J Adolesc Health 32:204-13. 2003
    ..To compare cytology with cervicography in HIV-infected and uninfected adolescent females...
  29. ncbi request reprint Risk of high-grade squamous intraepithelial lesion in HIV-infected adolescents
    Anna Barbara Moscicki
    Department of Pediatrics, University of California, San Francisco, California 94118 0503, USA
    J Infect Dis 190:1413-21. 2004
    ..We examined the risk of developing HSIL among adolescents with and without HIV infection...
  30. pmc Factors that influence the rate of epithelial maturation in the cervix in healthy young women
    Loris Y Hwang
    Department of Pediatrics, Division of Adolescent Medicine, University of California San Francisco, San Francisco, California 94118, USA
    J Adolesc Health 44:103-10. 2009
    ..To examine the longitudinal changes in the epithelial topography of the cervix in healthy young women; and to determine the sociodemographic, behavioral, and biological factors associated with the rate of cervical epithelial maturation...
  31. pmc Determination of cytokine protein levels in cervical mucus samples from young women by a multiplex immunoassay method and assessment of correlates
    Jay A Lieberman
    Division of Adolescent Medicine, Department of Pediatrics, University of California, San Francisco, California 94143, USA
    Clin Vaccine Immunol 15:49-54. 2008
    ..Cigarette smoking appears to downregulate cytokine responses in the cervical mucosa, which may help explain the implicated role of tobacco use as a cofactor for cervical cancer development...
  32. pmc A phase I randomized placebo controlled trial of the safety of 3% SPL7013 Gel (VivaGelĀ®) in healthy young women administered twice daily for 14 days
    Craig R Cohen
    Department of Obstetrics, Gynecology and Reproductive Science, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 6:e16258. 2011
    ..To assess the safety of VivaGelĀ® used vaginally twice daily for 14 days among healthy, sexually-abstinent women, aged 18-24 years in the USA and Kenya...
  33. pmc Increased levels of immune activation in the genital tract of healthy young women from sub-Saharan Africa
    Craig R Cohen
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, California 94117, USA
    AIDS 24:2069-74. 2010
    ..To determine whether healthy, young women in sub-Saharan Africa have a more activated immune milieu in the genital tract (i.e. activated CD4 T cells) than a similar population in the United States...
  34. pmc Association between toll-like receptor expression and human papillomavirus type 16 persistence
    Ibrahim I Daud
    Infectious Disease Research Training Program, University of California, San Francisco, CA 94118, USA
    Int J Cancer 128:879-86. 2011
    ....
  35. pmc Human papillomavirus concordance in heterosexual couples
    Lea E Widdice
    Division of Adolescent Medicine, Cincinnati Children s Research Foundation, University of Cincinnati, Cincinnati, Ohio 45229, USA
    J Adolesc Health 47:151-9. 2010
    ....
  36. pmc Investigating Potential Associations between Cervical Procedures and HIV Acquisition
    Khady Diouf
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco, San Francisco, CA 94143, USA
    ISRN Obstet Gynecol 2011:789106. 2011
    ..22), or loop electrosurgical excision procedure (RR 1.00, 95% CI 0.30-3.30). Conclusions. In this cohort, cervical procedures were not associated with HIV incidence. This lack of association could be due to the small number of events...
  37. doi request reprint 27. Natural history of anal HPV in heterosexual women and risks associated with persistence
    Anna Barbara Moscicki
    University of California, San Francisco, CA, USA
    Sex Health 10:583. 2013
    ..Sexual behaviour was associated with persistence, suggesting that education and behavioural interventions may decrease persistence and the risk of anal cancer. ..
  38. pmc Cervical cytokines and clearance of incident human papillomavirus infection: Hawaii HPV cohort study
    Mark E Scott
    Division of Adolescent Medicine, Department of Pediatrics, University of California, San Francisco, San Francisco, CA 94143 1374, USA
    Int J Cancer 133:1187-96. 2013
    ..Our results suggest that in women with a nontransient cervical HPV infection, proinflammatory, Type-1, and regulatory cytokines are elevated, underscoring the long-term commitment of local immune mediators to viral eradication. ..
  39. pmc Nicotine metabolism and addiction among adolescent smokers
    Mark L Rubinstein
    Division of Adolescent Medicine, University of California, San Francisco, CA 94118, USA
    Addiction 108:406-12. 2013
    ..The purpose of this study was to determine the association between the nicotine metabolic rate and smoking behavior, including addiction, in adolescent smokers...
  40. ncbi request reprint Cervical cytology screening in teens
    Anna Barbara Moscicki
    Division of Adolescent Medicine, Department of Pediatrics, University of California, San Francisco, 3333 California Street, Suite 245, San Francisco, CA 94118, USA
    Curr Womens Health Rep 3:433-7. 2003
    ..The new recommendations will assist in the over-referral and overtreatment of adolescents with HPV...
  41. ncbi request reprint Barriers to HAART adherence among human immunodeficiency virus-infected adolescents
    Debra A Murphy
    Health Risk Reduction Projects, Integrated Substance Abuse Programs, Department of Psychiatry, University of California, Los Angeles, 90025 3556, USA
    Arch Pediatr Adolesc Med 157:249-55. 2003
    ..To investigate the barriers to highly active antiretrovial therapy (HAART) adherence among human immunodeficiency virus (HIV)-infected adolescents and to explore the association of barriers and nonadherence...
  42. doi request reprint Cervical human papillomavirus incidence and persistence in a cohort of HIV-negative women in Zimbabwe
    Emily Fukuchi
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco, 2340 Sutter Street, San Francisco, CA 94143, USA
    Sex Transm Dis 36:305-11. 2009
    ..Little is known about the distribution of HPV types, independent risk factors of incidence and persistence, and patterns of persistence in sub-Saharan Africa...
  43. pmc Safety and immunogenicity of a quadrivalent human papillomavirus (types 6, 11, 16, and 18) vaccine in HIV-infected children 7 to 12 years old
    Myron J Levin
    Department of Pediatrics, University of Colorado Denver School of Medicine, Aurora, CO, USA
    J Acquir Immune Defic Syndr 55:197-204. 2010
    ..Quadrivalent human papillomavirus vaccine (QHPV) is > 95% effective in preventing infection with vaccine-type human papillomavirus. The safety and immunogenicity of QHPV are unknown in HIV-infected children...
  44. ncbi request reprint Cotinine levels in relation to smoking behavior and addiction in young adolescent smokers
    Mark L Rubinstein
    Division of Adolescent Medicine, University of California, San Francisco, San Francisco, CA 94118, USA
    Nicotine Tob Res 9:129-35. 2007
    ..497, p = .001), NDSS (r = 0.439, p = .002), timing of craving in the morning (r = -0.601, p = .000), and self-rated addiction (r = 0.562, p = .000). Most interesting, cotinine levels reached a plateau at around 4-5 cigarettes/day...
  45. doi request reprint Higher calorie diets increase rate of weight gain and shorten hospital stay in hospitalized adolescents with anorexia nervosa
    Andrea K Garber
    Division of Adolescent Medicine, University of California, San Francisco, San Francisco, California Electronic address
    J Adolesc Health 53:579-84. 2013
    ..We previously showed poor weight gain and long hospital stay using this approach and hypothesized that a higher calorie approach would improve outcomes...
  46. pmc Peripheral blood lymphocyte subsets in adolescents: a longitudinal analysis from the REACH project
    Bret J Rudy
    Children s Hospital of Philadelphia, Department of Pediatrics, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, 19104, USA
    Clin Diagn Lab Immunol 9:959-65. 2002
    ..Race and/or ethnicity was associated with differences in total CD8(+) cell counts and CD8(+) memory cell counts, although both of these associations involved an interaction with gender...
  47. ncbi request reprint CD8+CD38+ T cells but not HIV type 1 RNA viral load predict CD4+ T cell loss in a predominantly minority female HIV+ adolescent population
    Craig M Wilson
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    AIDS Res Hum Retroviruses 20:263-9. 2004
    ..This study extends the observed association of higher CD8(+) CD38(+) T cells numbers being predictive of HIV-1 disease progression into predominantly female, minority youth...
  48. pmc Updated guidelines for papanicolaou tests, colposcopy, and human papillomavirus testing in adolescents
    Lea E Widdice
    Division of Adolescent Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    J Adolesc Health 43:S41-51. 2008
    ....
  49. pmc Diminished IFN-gamma and IL-10 and elevated Foxp3 mRNA expression in the cervix are associated with CIN 2 or 3
    Mark E Scott
    Department of Pediatrics, University of California, San Francisco, CA 94143 1374, USA
    Int J Cancer 124:1379-83. 2009
    ..05). These findings support a model in which diminished cellular immunity in the cervical mucosa and mucosal enrichment of Treg cells both contribute to the development of high-grade lesions...
  50. pmc Methamphetamine use and risk for HIV among young men who have sex with men in 8 US cities
    Peter Freeman
    Division of General Pediatrics and Adolescent Medicine, Department of Pediatrics, The Johns Hopkins School of Medicine, 5200 Eastern Ave, Baltimore, MD 21224 2780, USA
    Arch Pediatr Adolesc Med 165:736-40. 2011
    ..To examine methamphetamine use and its association with sexual behavior among young men who have sex with men...
  51. ncbi request reprint Impact of HPV infection in adolescent populations
    Anna Barbara Moscicki
    Division of Adolescent Medicine, University of California, San Francisco, California 94143, USA
    J Adolesc Health 37:S3-9. 2005
    ..This article discusses HPV infection and the causal role that HPV plays in the development of low- and high-grade genital lesions, cervical cancer, and genital warts...
  52. ncbi request reprint Cervical cytology testing in teens
    Anna Barbara Moscicki
    Department of Pediatrics, University of California, San Francisco, San Francisco, California 94118, USA
    Curr Opin Obstet Gynecol 17:471-5. 2005
    ..These management strategies resulted in costly over-treatment. The purpose of this article is to review the evidence for the new guidelines in cytology screening in youth...
  53. ncbi request reprint Human papilloma virus, papanicolaou smears, and the college female
    Anna Barbara Moscicki
    Department of Pediatrics, Division of Adolescent Medicine, University of California, San Francisco, 3333 California Street, Suite 245, San Francisco, CA 94118, USA
    Pediatr Clin North Am 52:163-77, ix. 2005
    ..This article discusses human papilloma virus (HPV), Papanicolaou smears and the rational for new screening guidelines...
  54. pmc Different methods of identifying new antigenic epitopes of human papillomavirus type 16 E6 and E7 proteins
    Mayumi Nakagawa
    Department of Laboratory Medicine, School of Medicine, University of California at San Francisco, San Francisco, California, USA
    Clin Diagn Lab Immunol 11:889-96. 2004
    ..This is an efficient method of identifying new epitopes of antigens for which the number of specific T lymphocytes in the circulation is expected to be small, and it should be widely applicable in identifying new T-cell epitopes...
  55. pmc Correlates of HIV testing history among urban youth recruited through venue-based testing in 15 US cities
    Diane M Straub
    Department of Pediatrics, University of South Florida, Tampa, FL, USA
    Sex Transm Dis 38:691-6. 2011
    ..Our objective was to determine factors associated with history of HIV testing and receipt of results among a sample of urban, high-risk, sexually active adolescents in 15 US cities...
  56. doi request reprint Effect of diaphragm and lubricant gel provision on human papillomavirus infection among women provided with condoms: a randomized controlled trial
    George F Sawaya
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco, California 94118, USA
    Obstet Gynecol 112:990-7. 2008
    ..To estimate the effect of providing women with a latex diaphragm, lubricant gel, and male condoms (intervention) compared with condoms alone (control) on human papillomavirus (HPV) incidence and clearance...
  57. pmc Withdrawal in adolescent light smokers following 24-hour abstinence
    Mark L Rubinstein
    Division of Adolescent Medicine, University of California San Francisco, 3333 California Street, San Francisco, CA 94118, USA
    Nicotine Tob Res 11:185-9. 2009
    ..Withdrawal is one of the most important symptoms of nicotine addiction. We examined the extent to which adolescent light smokers experienced withdrawal symptoms when deprived of nicotine for a 24-hr period...
  58. ncbi request reprint Effects of pro- and anti-tobacco advertising on nonsmoking adolescents' intentions to smoke
    Diane M Straub
    Division of Adolescent Medicine, University of California, San Francisco, San Francisco, California, USA
    J Adolesc Health 32:36-43. 2003
    ..To determine the effects of pro- and anti-tobacco advertising on nonsmoking adolescents' intention to smoke in a single cohort...
  59. pmc Smoking-related cue-induced brain activation in adolescent light smokers
    Mark L Rubinstein
    Division of Adolescent Medicine, Department of Pediatrics, University of California San Francisco, 3333 California Street, San Francisco, CA 94118, USA
    J Adolesc Health 48:7-12. 2011
    ..To examine using functional magnetic resonance imaging whether adolescents with low levels of nicotine exposure (light smokers) display neural activation in areas shown to be involved with addiction in response to smoking-related stimuli...
  60. pmc Interlaboratory reproducibility of female genital tract cytokine measurements by Luminex: implications for microbicide safety studies
    Mark E Scott
    Division of Adolescent Medicine, Department of Pediatrics, School of Medicine, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA
    Cytokine 56:430-4. 2011
    ....
  61. pmc Cell-mediated immune responses to human papillomavirus 16 E6 and E7 antigens as measured by interferon gamma enzyme-linked immunospot in women with cleared or persistent human papillomavirus infection
    Sepideh Farhat
    Department of Pediatrics, School of Medicine, University of California, San Francisco, CA 94143, USA
    Int J Gynecol Cancer 19:508-12. 2009
    ..In summary, anti-E6 responses seem critical in the immediate control of HPV, and in some women, an immune tolerance eventually develops if HPV is not eliminated soon after infection...
  62. ncbi request reprint Associations among body composition, androgen levels, and human immunodeficiency virus status in adolescents
    Anna Barbara Moscicki
    Department of Pediatrics, University of California, San Francisco, San Francisco, California 94118, USA
    J Adolesc Health 39:164-73. 2006
    ..To investigate whether factors influencing body composition may be unique for male and female adolescents with horizontal transmission of human immunodeficiency virus (HIV)...
  63. pmc A randomized trial of nicotine nasal spray in adolescent smokers
    Mark L Rubinstein
    University of California, Division of Adolescent Medicine, 3333 California St, Suite 245, San Francisco, CA 94118, USA
    Pediatrics 122:e595-600. 2008
    ..The nasal sprayer has not been studied in adolescent smokers. The objective of this pilot study was to determine the feasibility and utility of using nicotine nasal spray for adolescent smokers who wanted to quit smoking...
  64. doi request reprint A prospective examination of weight gain in hospitalized adolescents with anorexia nervosa on a recommended refeeding protocol
    Andrea K Garber
    Division of Adolescent Medicine, University of California, San Francisco, California 94143, USA
    J Adolesc Health 50:24-9. 2012
    ..The purpose of this study was to examine weight change and clinical outcomes in hospitalized adolescents with AN on a recommended refeeding protocol...
  65. pmc Rate of nicotine metabolism and withdrawal symptoms in adolescent light smokers
    Mark L Rubinstein
    University of California, Division of Adolescent Medicine, 3333 California St, Suite 245, San Francisco, CA 94118, USA
    Pediatrics 122:e643-7. 2008
    ..The objectives of this study were to examine the associations between the rate of nicotine metabolism and cigarette consumption, addiction, and withdrawal symptoms in a sample of adolescent light smokers...
  66. ncbi request reprint American Cancer Society guideline for the early detection of cervical neoplasia and cancer
    Debbie Saslow
    Breast and Gynecologic Cancer, American Cancer Society, Atlanta, GA, USA
    CA Cancer J Clin 52:342-62. 2002
    ....
  67. ncbi request reprint External genital warts: diagnosis, treatment, and prevention
    D J Wiley
    Division of Primary Care, School of Nursing, University of California at Los Angeles, Los Angeles, CA 90095 6919, USA
    Clin Infect Dis 35:S210-24. 2002
    ..Because the efficacy of cesarean section in preventing vertical transmission of HPV infection from women with EGWs to their progeny has not been proved, it is not recommended...
  68. pmc Patterns of CD8 T-cell epitopes within the human papillomavirus type 16 (HPV 16) E6 protein among young women whose HPV 16 infection has become undetectable
    Mayumi Nakagawa
    Department of Dermatology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
    Clin Diagn Lab Immunol 12:1003-5. 2005
    ..T-cell lines were established using autologous dendritic cells infected with a recombinant vaccinia virus. Evidence of potential antigenic epitopes was shown in 8 of 23 (34.8%) women...
  69. pmc TH1 and TH2 cytokine mRNA and protein levels in human immunodeficiency virus (HIV)-seropositive and HIV-seronegative youths
    Steven D Douglas
    Division of Allergy Immunology, Joseph Stokes, Jr Research Institute, The Children s Hospital of Philadelphia, and Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Clin Diagn Lab Immunol 10:399-404. 2003
    ..On the basis of our data, we conclude that, early in the course of HIV-associated disease in adolescents, there are no detectable shifts from TH1 to TH2 cytokine production...
  70. pmc HLA class I binding promiscuity of the CD8 T-cell epitopes of human papillomavirus type 16 E6 protein
    Mayumi Nakagawa
    Department of Dermatology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
    J Virol 81:1412-23. 2007
    ..The HLA class I promiscuity which has been described for human immunodeficiency virus may be more common than previously recognized...
  71. ncbi request reprint Human herpesvirus 8 infection among adolescents in the REACH cohort
    Corey Casper
    Departments of Medicine, Laboratory Medicine, and Epidemiology, University of Washington, Seattle, USA
    Arch Pediatr Adolesc Med 160:937-42. 2006
    ..We examined the prevalence and predictors of HHV-8 infection among adolescents with or at high risk for acquiring HIV infection...
  72. ncbi request reprint Sustained efficacy up to 4.5 years of a bivalent L1 virus-like particle vaccine against human papillomavirus types 16 and 18: follow-up from a randomised control trial
    Diane M Harper
    Department of Obstetrics and Gynecology, Norris Cotton Cancer Center, Dartmouth Medical School, Rubin 880, One Medical Center Drive, Lebanon, NH 03756, USA
    Lancet 367:1247-55. 2006
    ....
  73. ncbi request reprint Advances in prevention of cervical cancer and other human papillomavirus-related diseases
    Ian H Frazer
    University of Queensland, Center for Immunology and Cancer Research, Brisbane, QLD 4072, Australia
    Pediatr Infect Dis J 25:S65-81, quiz S82. 2006
  74. ncbi request reprint A 23-year-old woman has her first Pap smear, thin prep smear interpreted as "high grade squamous intraepithelial lesion"
    Klaus Diem
    Madison, WI, USA
    J Low Genit Tract Dis 12:54-8. 2008
  75. pmc Memory T cells specific for novel human papillomavirus type 16 (HPV16) E6 epitopes in women whose HPV16 infection has become undetectable
    Xuelian Wang
    Department of Pathology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
    Clin Vaccine Immunol 15:937-45. 2008
    ..The characterization of novel T-cell epitopes and long-lasting epitope-specific memory T cells may be useful for the development of a potential epitope-based vaccine...
  76. ncbi request reprint American Cancer Society Guideline for human papillomavirus (HPV) vaccine use to prevent cervical cancer and its precursors
    Debbie Saslow
    Cancer Control Science Department, American Cancer Society, Altanta, GA, USA
    CA Cancer J Clin 57:7-28. 2007
    ..They address the use of prophylactic HPV vaccines, including who should be vaccinated and at what age, as well as a summary of policy and implementation issues. Implications for screening are also discussed...
  77. ncbi request reprint Using qualitative research to inform survey development on nicotine dependence among adolescents
    Mark Nichter
    Department of Anthropology, 1009 E South Campus Drive, Building 30, University of Arizona, Tucson, AZ 85721 0030, USA
    Drug Alcohol Depend 68:S41-56. 2002
    ..Following a formative research process like this one will help tobacco researchers gain a better understanding of how nicotine dependence develops...
  78. doi request reprint Issues in human papillomavirus vaccination in adolescents
    Anna Barbara Moscicki
    J Adolesc Health 43:S1-4. 2008

Research Grants31

  1. Natural History of CIN2 in Adolescents
    Anna Barbara Moscicki; Fiscal Year: 2001
    ..abstract_text> ..
  2. NATURAL HISTORY OF HPV--INFECTION TO NEOPLASIA
    Anna Barbara Moscicki; Fiscal Year: 2001
    ..The understanding of both local and systemic immune responses to initial and subsequent HPV infections may be key in vaccine or therapeutic developments. ..
  3. Natural History of CIN2 in Adolescents
    Anna Barbara Moscicki; Fiscal Year: 2002
    ..abstract_text> ..
  4. NATURAL HISTORY OF HPV--INFECTION TO NEOPLASIA
    Anna Barbara Moscicki; Fiscal Year: 2002
    ..The understanding of both local and systemic immune responses to initial and subsequent HPV infections may be key in vaccine or therapeutic developments. ..
  5. Natural History of CIN2 in Adolescents
    Anna Barbara Moscicki; Fiscal Year: 2003
    ..abstract_text> ..
  6. NATURAL HISTORY OF HPV--INFECTION TO NEOPLASIA
    Anna Barbara Moscicki; Fiscal Year: 2003
    ..The understanding of both local and systemic immune responses to initial and subsequent HPV infections may be key in vaccine or therapeutic developments. ..
  7. Natural History of CIN2 in Adolescents
    Anna Barbara Moscicki; Fiscal Year: 2004
    ..abstract_text> ..
  8. NATURAL HISTORY OF HPV--INFECTION TO NEOPLASIA
    Anna Barbara Moscicki; Fiscal Year: 2004
    ..The understanding of both local and systemic immune responses to initial and subsequent HPV infections may be key in vaccine or therapeutic developments. ..
  9. Natural History of CIN2 in Adolescents
    Anna Barbara Moscicki; Fiscal Year: 2005
    ..abstract_text> ..
  10. A San Francisco Street Youth Cohort: At Risk and HIV+
    Anna Barbara Moscicki; Fiscal Year: 2007
    ..We believe it is critical to continue to engage the high risk youth in the San Francisco Bay Area in clinical and behavioral research. ..
  11. Natural History of HPV Infection to Neoplasia
    Anna Barbara Moscicki; Fiscal Year: 2007
    ..Information garnered from this type of study will be critical in developing vaccine strategies and therapies as well as illuminating immune responses developed in the mucosal epithelium. ..
  12. A San Francisco Street Youth Cohort: At Risk and HIV+
    Anna Barbara Moscicki; Fiscal Year: 2008
    ..We believe it is critical to continue to engage the high risk youth in the San Francisco Bay Area in clinical and behavioral research. ..
  13. Natural History of HPV Infection to Neoplasia
    Anna Barbara Moscicki; Fiscal Year: 2008
    ..Information garnered from this type of study will be critical in developing vaccine strategies and therapies as well as illuminating immune responses developed in the mucosal epithelium. ..
  14. NATURAL HISTORY OF HPV--INFECTION TO NEOPLASIA
    Anna Barbara Moscicki; Fiscal Year: 2000
    ..The understanding of both local and systemic immune responses to initial and subsequent HPV infections may be key in vaccine or therapeutic developments. ..
  15. NATURAL HISTORY OF HPV IN TEENS--INFECTION TO NEOPLASIA
    Anna Barbara Moscicki; Fiscal Year: 1993
    ..The results from this study will be related to the prevention and education of pre-cancer lesions in young women as well as identifying a clinical model for the role of viruses in abnormal cellular development...
  16. NATURAL HISTORY OF HPV IN TEENS--INFECTION TO NEOPLASIA
    Anna Barbara Moscicki; Fiscal Year: 1992
    ..The results from this study will be related to the prevention and education of pre-cancer lesions in young women as well as identifying a clinical model for the role of viruses in abnormal cellular development...
  17. NATURAL HISTORY OF HPV IN TEENS--INFECTION TO NEOPLASIA
    Anna Barbara Moscicki; Fiscal Year: 1999
    ..The results from this study will be related to the prevention and education of pre-cancer lesions in young women as well as identifying a clinical model for the role of viruses in abnormal cellular development. ..
  18. NATURAL HISTORY OF HPV IN TEENS--INFECTION TO NEOPLASIA
    Anna Barbara Moscicki; Fiscal Year: 1990
    ..The results from this study will be related to the prevention and education of pre-cancer lesions in young women as well as identifying a clinical model for the role of viruses in abnormal cellular development...
  19. NATURAL HISTORY OF HPV IN TEENS--INFECTION TO NEOPLASIA
    Anna Barbara Moscicki; Fiscal Year: 1991
    ..The results from this study will be related to the prevention and education of pre-cancer lesions in young women as well as identifying a clinical model for the role of viruses in abnormal cellular development...
  20. Natural History of CIN2 in Adolescents
    Anna Barbara Moscicki; Fiscal Year: 2007
    ..S. and specifically assess how best to modify cytology-based screening, utilize HPV diagnostics, and tailor aoDrooriate follow-uo strategies for adolescents and vouna women diaanosed with CIN 2 ..