Kari M Morrissey
Affiliation: University of California
- Renal transporters in drug developmentKari M Morrissey
Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, California 94158, USA
Annu Rev Pharmacol Toxicol 53:503-29. 2013..Renal drug elimination in special populations and transporter splicing variants are also described...
- Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modelingMatthias B Wittwer
University of California, San Francisco, Department of Bioengineering and Therapeutic Sciences RH 581, 1550 Fourth Street, San Francisco, California 94158, USA
J Med Chem 56:781-95. 2013..In parallel, a QSAR model identified distinct molecular properties of MATE1 versus OCT2 inhibitors and was used to screen the DrugBank in silico library for new hits in a larger chemical space...