RALPH CURTIS MORRIS
Affiliation: University of California
- Differing effects of supplemental KCl and KHCO3: pathophysiological and clinical implicationsR C Morris
Department of Medicine, The University of California, San Francisco 94143 0126, USA
Semin Nephrol 19:487-93. 1999....
- Relationship and interaction between sodium and potassiumR Curtis Morris
Department of Medicine, University of California at San Francisco, San Francisco, CA 94143 0126, USA
J Am Coll Nutr 25:262S-270S. 2006....
- Chloride-dominant salt sensitivity in the stroke-prone spontaneously hypertensive ratOlga Schmidlin
Department of Medicine, Division of Nephrology, University of California at San Francisco, CA 94143 0126, USA
Hypertension 45:867-73. 2005..We conclude that in the SHRSP, the Cl- component of a dietary NaCl dominantly determines salt sensitivity and thereby phenotypic expression. We suggest that Cl- might do so by inducing renal vasoconstriction...
- Sodium-selective salt sensitivity: its occurrence in blacksOlga Schmidlin
Division of Nephrology, Department of Medicine, University of California San Francisco, 1291 Moffitt Hospital, CA 94143 0126, USA
Hypertension 50:1085-92. 2007....
- Adverse effects of sodium chloride on bone in the aging human population resulting from habitual consumption of typical American dietsLynda A Frassetto
University of California, San Francisco, California, CA 94143, USA
J Nutr 138:419S-422S. 2008..We focus here on the American diet's potential effects on bone through its superphysiologic content of sodium chloride...
- Dietary sodium chloride intake independently predicts the degree of hyperchloremic metabolic acidosis in healthy humans consuming a net acid-producing dietLynda A Frassetto
Dept of Medicine and General Clinical Research Center, University of California, San Francisco, CA 94143, USA
Am J Physiol Renal Physiol 293:F521-5. 2007..Assuming a causal relationship, over their respective ranges of variation, NaCl has approximately 50-100% of the acidosis-producing effect of the diet net acid load...
- What initiates the pressor effect of salt in salt-sensitive humans? Observations in normotensive blacksOlga Schmidlin
Division of Nephrology, Department of Medicine, University of California San Francisco, 94143 0126, USA
Hypertension 49:1032-9. 2007..In SS and SR subjects combined, changes in both MAP and SVR on day 2 strongly predicted changes in MAP on day 7. In many normotensive blacks, vascular dysfunction is critical to the initiation of a pressor response to dietary NaCl...
- Selective chloride loading is pressor in the stroke-prone spontaneously hypertensive rat despite hydrochlorothiazide-induced natriuresisOlga Schmidlin
Department of Medicine, Division of Nephrology, University of California San Francisco, San Francisco, California 94143 0126, USA
J Hypertens 28:87-94. 2010..To test the hypothesis that in the stroke-prone spontaneously hypertensive rat (SHRSP), the pressor effect of selective dietary chloride loading depends on a positive external sodium balance...
- Long-term persistence of the urine calcium-lowering effect of potassium bicarbonate in postmenopausal womenLynda Frassetto
Department of Medicine, University of California, San Francisco, CA 94143, USA
J Clin Endocrinol Metab 90:831-4. 2005..Thus, one can preselect postmenopausal women most likely to have the urine calcium-lowering effect of KBC and predict their potential bone calcium increase...
- Estimation of the net acid load of the diet of ancestral preagricultural Homo sapiens and their hominid ancestorsAnthony Sebastian
Department of Medicine and the General Clinical Research Center, University of California, San Francisco, California 94143, USA
Am J Clin Nutr 76:1308-16. 2002..Natural selection has had < 1% of hominid evolutionary time to eliminate the inevitable maladaptations consequent to the profound transformation of the human diet resulting from the inventions of agriculture and animal husbandry...
- The evolution-informed optimal dietary potassium intake of human beings greatly exceeds current and recommended intakesAnthony Sebastian
Department of Medicine, Division of Nephrology, Moffitt Mt Zion General Clinical Research Center, UCSF, San Francisco, CA 94303, USA
Semin Nephrol 26:447-53. 2006..We discuss the potential implications of our findings in respect to human health and disease...