Alison Morris

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint Update on the epidemiology and transmission of Pneumocystis carinii
    Alison Morris
    Department of Medicine, San Francisco General Hospital, University of California, San Francisco, CA, USA
    Microbes Infect 4:95-103. 2002
  2. ncbi request reprint Intensive care of human immunodeficiency virus-infected patients during the era of highly active antiretroviral therapy
    Alison Morris
    Department of Medicine, San Francisco General Hospital, University of California, San Francisco, CA, USA
    Am J Respir Crit Care Med 166:262-7. 2002
  3. ncbi request reprint Improved survival with highly active antiretroviral therapy in HIV-infected patients with severe Pneumocystis carinii pneumonia
    Alison Morris
    Department of Medicine, San Francisco General Hospital, San Francisco, California, USA
    AIDS 17:73-80. 2003
  4. ncbi request reprint Severity and outcome of HIV-associated Pneumocystis pneumonia containing Pneumocystis jirovecii dihydropteroate synthase gene mutations
    Kristina Crothers
    Positive Health Program and Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, University of California, San Francisco, California, USA
    AIDS 19:801-5. 2005
  5. ncbi request reprint Pneumocystis colonization in HIV-infected patients
    Laurence Huang
    Division of Pulmonary and Critical Care Medicine and Positive Health Program, San Francisco General Hospital, University of California San Francisco, San Francisco, CA 94110, USA
    J Eukaryot Microbiol 50:616-7. 2003
  6. pmc Asthma diagnosis and airway bronchodilator response in HIV-infected patients
    Matthew R Gingo
    Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    J Allergy Clin Immunol 129:708-714.e8. 2012
  7. pmc Cardiopulmonary function in individuals with HIV infection in the antiretroviral therapy era
    Alison Morris
    Department of Medicine, University of Alabama, Birmingham, USA
    AIDS 26:731-40. 2012
  8. pmc HIV infection is associated with reduced pulmonary diffusing capacity
    Kristina Crothers
    Department of Medicine, University of Washington, Seattle, WA Department of Medicine, University of Pittsburgh, Pittsburgh, PA Department of Medicine, University of California, Los Angeles, Los Angeles, CA Department of Medicine, Atlanta Veterans Affairs Medical Center VAMC and Emory University, Atlanta, GA Department of Medicine, West Los Angeles VAMC and David Geffen School of Medicine at University of California Los Angeles UCLA, Los Angeles, CA Department of Medicine, James J Peters Bronx VAMC, Bronx, NY Department of Medicine, Michael E DeBakey Houston VAMC and Baylor College of Medicine, Houston, TX Department of Medicine, University of California, San Francisco, San Francisco, CA Department of Medicine, Clinical Trials and Survey Corporation, Owings Mills, MD Department of Medicine, Ohio State University Medical Center, Columbus, OH Department of Medicine, Johns Hopkins University, Baltimore, MD Department of Medicine, New York University School of Medicine, New York, NY Departments of Infectious Diseases and Microbiology and Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA and Departments of Medicine and Immunology, University of Pittsburgh, Pittsburgh, PA
    J Acquir Immune Defic Syndr 64:271-8. 2013
  9. pmc HIV infection is associated with diffusing capacity impairment in women
    Meghan E Fitzpatrick
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA Department of Clinical Pharmacy, School of Pharmacy, University of California, San Francisco, CA Departments of Medicine Epidemiology and Biostatistics, School of Medicine, University of California, San Francisco, CA and Department of Immunology, University of Pittsburgh, Pittsburgh, PA
    J Acquir Immune Defic Syndr 64:284-8. 2013
  10. pmc HIV and chronic obstructive pulmonary disease: is it worse and why?
    Alison Morris
    Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Proc Am Thorac Soc 8:320-5. 2011

Collaborators

Detail Information

Publications42

  1. ncbi request reprint Update on the epidemiology and transmission of Pneumocystis carinii
    Alison Morris
    Department of Medicine, San Francisco General Hospital, University of California, San Francisco, CA, USA
    Microbes Infect 4:95-103. 2002
    ..This review summarizes the current state of knowledge about the epidemiology and transmission of P. carinii and reports on evolving techniques that may improve our understanding of this organism in the future...
  2. ncbi request reprint Intensive care of human immunodeficiency virus-infected patients during the era of highly active antiretroviral therapy
    Alison Morris
    Department of Medicine, San Francisco General Hospital, University of California, San Francisco, CA, USA
    Am J Respir Crit Care Med 166:262-7. 2002
    ..These patients may have an improved survival because of effects of therapy on variables such as likelihood of non-AIDS-associated admission diagnoses and serum albumin levels...
  3. ncbi request reprint Improved survival with highly active antiretroviral therapy in HIV-infected patients with severe Pneumocystis carinii pneumonia
    Alison Morris
    Department of Medicine, San Francisco General Hospital, San Francisco, California, USA
    AIDS 17:73-80. 2003
    ..Highly active antiretroviral therapy (HAART) might alter the course of PCP either via effects on the immune system or through anti- actions; however, HAART has not been studied in patients acutely ill with PCP...
  4. ncbi request reprint Severity and outcome of HIV-associated Pneumocystis pneumonia containing Pneumocystis jirovecii dihydropteroate synthase gene mutations
    Kristina Crothers
    Positive Health Program and Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, University of California, San Francisco, California, USA
    AIDS 19:801-5. 2005
    ..The impact of Pneumocystis jirovecii (formerly P. carinii) dihydropteroate synthase (DHPS) gene mutations on morbidity and mortality of Pneumocystis pneumonia (PCP) in HIV-positive patients is unclear...
  5. ncbi request reprint Pneumocystis colonization in HIV-infected patients
    Laurence Huang
    Division of Pulmonary and Critical Care Medicine and Positive Health Program, San Francisco General Hospital, University of California San Francisco, San Francisco, CA 94110, USA
    J Eukaryot Microbiol 50:616-7. 2003
  6. pmc Asthma diagnosis and airway bronchodilator response in HIV-infected patients
    Matthew R Gingo
    Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    J Allergy Clin Immunol 129:708-714.e8. 2012
    ....
  7. pmc Cardiopulmonary function in individuals with HIV infection in the antiretroviral therapy era
    Alison Morris
    Department of Medicine, University of Alabama, Birmingham, USA
    AIDS 26:731-40. 2012
    ..To determine relationship of echocardiographic measures of pulmonary hypertension to lung function and inflammatory biomarkers in HIV-infected individuals...
  8. pmc HIV infection is associated with reduced pulmonary diffusing capacity
    Kristina Crothers
    Department of Medicine, University of Washington, Seattle, WA Department of Medicine, University of Pittsburgh, Pittsburgh, PA Department of Medicine, University of California, Los Angeles, Los Angeles, CA Department of Medicine, Atlanta Veterans Affairs Medical Center VAMC and Emory University, Atlanta, GA Department of Medicine, West Los Angeles VAMC and David Geffen School of Medicine at University of California Los Angeles UCLA, Los Angeles, CA Department of Medicine, James J Peters Bronx VAMC, Bronx, NY Department of Medicine, Michael E DeBakey Houston VAMC and Baylor College of Medicine, Houston, TX Department of Medicine, University of California, San Francisco, San Francisco, CA Department of Medicine, Clinical Trials and Survey Corporation, Owings Mills, MD Department of Medicine, Ohio State University Medical Center, Columbus, OH Department of Medicine, Johns Hopkins University, Baltimore, MD Department of Medicine, New York University School of Medicine, New York, NY Departments of Infectious Diseases and Microbiology and Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA and Departments of Medicine and Immunology, University of Pittsburgh, Pittsburgh, PA
    J Acquir Immune Defic Syndr 64:271-8. 2013
    ..Prior studies comparing abnormalities in pulmonary function between HIV-infected and HIV-uninfected persons in the current era are limited...
  9. pmc HIV infection is associated with diffusing capacity impairment in women
    Meghan E Fitzpatrick
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA Department of Clinical Pharmacy, School of Pharmacy, University of California, San Francisco, CA Departments of Medicine Epidemiology and Biostatistics, School of Medicine, University of California, San Francisco, CA and Department of Immunology, University of Pittsburgh, Pittsburgh, PA
    J Acquir Immune Defic Syndr 64:284-8. 2013
    ..Providers should be aware that DL(CO) impairment is common in HIV infection, and that either DL(CO) impairment or airflow obstruction may cause respiratory symptoms in this population...
  10. pmc HIV and chronic obstructive pulmonary disease: is it worse and why?
    Alison Morris
    Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Proc Am Thorac Soc 8:320-5. 2011
    ....
  11. ncbi request reprint Current issues in critical care of the human immunodeficiency virus-infected patient
    Alison Morris
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Crit Care Med 34:42-9. 2006
    ....
  12. pmc Pulmonary function abnormalities in HIV-infected patients during the current antiretroviral therapy era
    Matthew R Gingo
    Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Am J Respir Crit Care Med 182:790-6. 2010
    ..The prevalence and exact phenotype of pulmonary abnormalities in the current era are unknown. In addition, these abnormalities may be underdiagnosed...
  13. ncbi request reprint Prevalence and clinical predictors of Pneumocystis colonization among HIV-infected men
    Alison Morris
    Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    AIDS 18:793-8. 2004
    ..The epidemiology and transmission of Pneumocystis are poorly understood. The incidence of colonization, or detection of organisms without signs of disease, has been debated, and risk factors for colonization are largely unknown...
  14. pmc Outcome of HIV-associated Pneumocystis pneumonia in hospitalized patients from 2000 through 2003
    Saba Radhi
    Department of Medicine, Division of Pulmonary and Critical Care Medicine and the Will Rogers Institute Pulmonary Research Center, University of Southern California, Los Angeles, CA, USA
    BMC Infect Dis 8:118. 2008
    ..Epidemiology of PCP in the recent era of highly active antiretroviral therapy (HAART) is not well known and the impact of HAART on outcome of PCP has been debated...
  15. ncbi request reprint Pneumocystis jirovecii colonization is associated with enhanced Th1 inflammatory gene expression in lungs of humans with chronic obstructive pulmonary disease
    Meghan E Fitzpatrick
    Department of Medicine, University of Pittsburgh, 3459 Fifth Avenue, Pittsburgh, Pennsylvania, 15213, USA
    Microbiol Immunol 58:202-11. 2014
    ..The finding of upregulation of these inflammatory genes in the setting of Pneumocystis colonization sheds light on infectious-immune relationships in COPD. ..
  16. pmc Pulmonary symptoms and diagnoses are associated with HIV in the MACS and WIHS cohorts
    Matthew R Gingo
    Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    BMC Pulm Med 14:75. 2014
    ..The objective of the study is to determine the impact of HIV on prevalence and incidence of respiratory disease in the current era of effective antiretroviral treatment...
  17. pmc Human immunodeficiency virus-associated obstructive lung diseases
    Matthew R Gingo
    Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Clin Chest Med 34:273-82. 2013
    ..This article reviews the evidence linking HIV infection to obstructive lung disease, and discusses management issues related to the treatment of obstructive lung disease in HIV-infected patients...
  18. pmc Comparison of the respiratory microbiome in healthy nonsmokers and smokers
    Alison Morris
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Am J Respir Crit Care Med 187:1067-75. 2013
    ..Results from 16S rDNA-encoding gene sequence-based, culture-independent techniques have led to conflicting conclusions about the composition of the lower respiratory tract microbiome...
  19. pmc Future directions: lung aging, inflammation, and human immunodeficiency virus
    Meghan Fitzpatrick
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Clin Chest Med 34:325-31. 2013
    ..This article describes how HIV-associated COPD and PH may fit into a paradigm of immunosenescence, and outlines the hypothesized associations among chronic HIV infection, immune dysfunction and senescence, and cardiopulmonary outcomes...
  20. pmc Current epidemiology of Pneumocystis pneumonia
    Alison Morris
    University of Southern California, Los Angeles, California, USA
    Emerg Infect Dis 10:1713-20. 2004
    ....
  21. pmc Serologic responses to pneumocystis proteins in HIV patients with and without Pneumocystis jirovecii pneumonia
    Matthew R Gingo
    Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    J Acquir Immune Defic Syndr 57:190-6. 2011
    ..Immune responses to Pneumocystis jirovecii are not well understood in HIV infection, but antibody responses to proteins may be useful as a marker of Pneumocystis risk or presence of Pneumocystis pneumonia (PcP)...
  22. pmc The impact of HAART on the respiratory complications of HIV infection: longitudinal trends in the MACS and WIHS cohorts
    Matthew R Gingo
    Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    PLoS ONE 8:e58812. 2013
    ..To review the incidence of respiratory conditions and their effect on mortality in HIV-infected and uninfected individuals prior to and during the era of highly active antiretroviral therapy (HAART)...
  23. pmc Pathogenesis of HIV and the lung
    Matthew R Gingo
    Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Curr HIV/AIDS Rep 10:42-50. 2013
    ..The effect of HIV infection on lung-specific immune responses is being elucidated to help develop better prevention and treatment strategies in HIV-infected persons...
  24. pmc Distribution of Pneumocystis jirovecii in lungs from colonized COPD patients
    Sheila Sivam
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Diagn Microbiol Infect Dis 71:24-8. 2011
    ....
  25. pmc Airway obstruction is increased in pneumocystis-colonized human immunodeficiency virus-infected outpatients
    Alison Morris
    University of Pittsburgh Medical Center, 628 NW MUH, 3459 Fifth Avenue, Pittsburgh, PA 15213, USA
    J Clin Microbiol 47:3773-6. 2009
    ..Pneumocystis-colonized subjects had worse obstruction of airways and higher levels of matrix metalloprotease-12 in sputa, suggesting that Pneumocystis colonization may be important in HIV-associated chronic obstructive pulmonary disease...
  26. pmc Pneumocystis: a novel pathogen in chronic obstructive pulmonary disease?
    Alison Morris
    Division of Pulmonary, Allergy, and Critical Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    COPD 5:43-51. 2008
    ..Additional studies are needed to confirm the role of Pneumocystis in the pathogenesis of COPD, given that this agent might be a treatable co-factor in disease progression...
  27. doi request reprint Epidemiology and clinical significance of pneumocystis colonization
    Alison Morris
    Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    J Infect Dis 197:10-7. 2008
    ..We also evaluate the clinical significance of Pneumocystis colonization and its relationship to lung disease...
  28. pmc STAT4-dependent and -independent Th2 responses correlate with protective immunity against lung infection with Pneumocystis murina
    Riley C Myers
    Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    J Immunol 190:6287-94. 2013
    ..Collectively, our data suggest that robust local and systemic Th2-mediated responses are critical for immunity to Pneumocystis...
  29. pmc Respiratory symptoms and airway obstruction in HIV-infected subjects in the HAART era
    M Patricia George
    Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    PLoS ONE 4:e6328. 2009
    ..We evaluated respiratory symptoms and measured airway obstruction to identify the impact of HAART and other risk factors on respiratory symptoms and pulmonary function...
  30. ncbi request reprint Pneumocystis dihydropteroate synthase mutations in patients with Pneumocystis pneumonia who are newly diagnosed with HIV infection
    Kristina Crothers
    Division of Pulmonary and Critical Care Medicine and Positive Health Program, San Francisco General Hospital, University of California San Francisco, San Francisco, CA 94110, USA
    J Eukaryot Microbiol 50:609-10. 2003
  31. pmc Relationship of pneumocystis antibody response to severity of chronic obstructive pulmonary disease
    Alison Morris
    Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Clin Infect Dis 47:e64-8. 2008
    ..Undetectable anti-Pneumocystis antibody titer was an independent predictor of more-severe airway obstruction, although use of inhaled corticosteroids is a possible confounder of this effect...
  32. doi request reprint Detailed analysis of the radiographic presentation of Mycobacterium kansasii lung disease in patients with HIV infection
    Adithya Cattamanchi
    University of California San Francisco, San Francisco General Hospital, San Francisco, CA 94110, USA
    Chest 133:875-80. 2008
    ..In patients with HIV infection, the radiographic findings of M kansasii lung disease are not well described...
  33. pmc Pulmonary vascular lesions are common in SIV- and SHIV-env-infected macaques
    M Patricia George
    Department of Medicine, University of Pittsburgh, Pennsylvania 15213, USA
    AIDS Res Hum Retroviruses 27:103-11. 2011
    ..This SHIV-env model provides a new means to investigate HIV-PAH...
  34. pmc Epidemiology of Pneumocystis colonization in families
    LaShonda Spencer
    Maternal Child and Adolescent Center for Infectious Diseases and Virology, Division of Pulmonary and Critical Care Medicine and Will Rogers Institute Pulmonary Research Center, University of Southern California, Los Angeles, USA
    Clin Infect Dis 46:1237-40. 2008
    ..Using nested polymerase chain reaction of oropharyngeal or nasopharyngeal samples, we detected colonization in 11.4% of HIV-infected adults and in 3.3% of their children, but there was no evidence of clustering...
  35. ncbi request reprint Intensive care of patients with HIV infection: HAART warming improvement but beware of future HAART (and heart) attacks
    Alison Morris
    Chest 125:1602-4. 2004
  36. ncbi request reprint Mortality prediction in pulmonary Mycobacterium kansasii infection and human immunodeficiency virus
    Theodore K Marras
    Department of Medicine Respiratory, University of Toronto, Ontario, Canada
    Am J Respir Crit Care Med 170:793-8. 2004
    ..Withholding treatment in HIV-infected patients with respiratory M. kansasii isolates should only be considered with negative smear microscopy, few positive cultures, and mild immunosuppression...
  37. ncbi request reprint Association of chronic obstructive pulmonary disease severity and Pneumocystis colonization
    Alison Morris
    M S, Division of Pulmonary and Critical Care Medicine, 2011 Zonal Avenue, Los Angeles, CA 90033, USA
    Am J Respir Crit Care Med 170:408-13. 2004
    ..001) and was independent of smoking history. We conclude that there is a strong association between Pneumocystis colonization and severity of airflow obstruction in smokers, suggesting a possible pathogenic link with COPD progression...
  38. ncbi request reprint A prospective, blinded study of quantitative touch-down polymerase chain reaction using oral-wash samples for diagnosis of Pneumocystis pneumonia in HIV-infected patients
    Hans Henrik Larsen
    Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Infect Dis 189:1679-83. 2004
    ..QTD PCR of oral-wash samples can be an accurate and noninvasive method for diagnosis of PCP...
  39. ncbi request reprint An Official ATS Workshop Summary: Recent advances and future directions in pneumocystis pneumonia (PCP)
    Laurence Huang
    Proc Am Thorac Soc 3:655-64. 2006
    ..The workshop included 21 presentations on diverse topics, which are summarized in this report. The workshop participants identified priorities for future research, which are summarized in this document...
  40. pmc Antibody response to Pneumocystis jirovecii major surface glycoprotein
    Kieran R Daly
    Research Service 151, Veterans Affairs Medical Center, 3200 Vine Street, Cincinnati, OH 45220, USA
    Emerg Infect Dis 12:1231-7. 2006
    ..001). Thus, MsgC shows promise as a serologic reagent and should be tested further in clinical and epidemiologic studies...
  41. ncbi request reprint Pneumocystis colonization, airway inflammation, and pulmonary function decline in acquired immunodeficiency syndrome
    Karen A Norris
    Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
    Immunol Res 36:175-87. 2006
    ..Information gained from these studies will lead to the development of interventions to prevent lung injury associated with Pc colonization and the development of HIV-associated COPD...
  42. ncbi request reprint Is there anything new in Pneumocystis jirovecii pneumonia? Changes in P. jirovecii pneumonia over the course of the AIDS epidemic
    Alison Morris
    Clin Infect Dis 46:634-6. 2008