John C Morrill

Summary

Affiliation: University of Texas Medical Branch
Country: USA

Publications

  1. doi request reprint Protection of MP-12-vaccinated rhesus macaques against parenteral and aerosol challenge with virulent rift valley fever virus
    John C Morrill
    United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, USA
    J Infect Dis 204:229-36. 2011
  2. pmc Immunogenicity of a recombinant Rift Valley fever MP-12-NSm deletion vaccine candidate in calves
    John C Morrill
    Department of Microbiology and Immunology, The University of Texas Medical Branch at Galveston, 301 University Blvd, Room 4 142B MRB, Galveston, TX 77555 1019, USA Electronic address
    Vaccine 31:4988-94. 2013
  3. pmc Safety and immunogenicity of recombinant Rift Valley fever MP-12 vaccine candidates in sheep
    John C Morrill
    Department of Microbiology and Immunology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555 1019, USA
    Vaccine 31:559-65. 2013
  4. doi request reprint Mucosal immunization of rhesus macaques with Rift Valley Fever MP-12 vaccine
    John C Morrill
    Applied Research Division, US Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, USA
    J Infect Dis 204:617-25. 2011
  5. pmc Rapid accumulation of virulent rift valley Fever virus in mice from an attenuated virus carrying a single nucleotide substitution in the m RNA
    John C Morrill
    Department of Microbiology and Immunology, The University of Texas Medical Branch at Galveston, Galveston, Texas, United States of America
    PLoS ONE 5:e9986. 2010
  6. pmc Genetic subpopulations of Rift Valley fever virus strains ZH548 and MP-12 and recombinant MP-12 strains
    Nandadeva Lokugamage
    Department of Pathology, University of Texas Medical Branch, Galveston, Texas, USA
    J Virol 86:13566-75. 2012
  7. doi request reprint Development of a novel, single-cycle replicable rift valley Fever vaccine
    Shin Murakami
    Department of Microbiology and Immunology, The University of Texas Medical Branch, Galveston, Texas, United States of America
    PLoS Negl Trop Dis 8:e2746. 2014

Collaborators

Detail Information

Publications7

  1. doi request reprint Protection of MP-12-vaccinated rhesus macaques against parenteral and aerosol challenge with virulent rift valley fever virus
    John C Morrill
    United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, USA
    J Infect Dis 204:229-36. 2011
    ..The mutagen-attenuated RVF MP-12 vaccine was determined to be protective against intravenous and aerosol challenge with virulent RVFV in these macaques, which suggests further development as a vaccine for humans is warranted...
  2. pmc Immunogenicity of a recombinant Rift Valley fever MP-12-NSm deletion vaccine candidate in calves
    John C Morrill
    Department of Microbiology and Immunology, The University of Texas Medical Branch at Galveston, 301 University Blvd, Room 4 142B MRB, Galveston, TX 77555 1019, USA Electronic address
    Vaccine 31:4988-94. 2013
    ..m. to calves will consistently stimulate a presumably protective PRNT80 response for at least 91 days post inoculation. Further studies of arMP-12ΔNSm21/384 are warranted to explore its suitability as an efficacious livestock vaccine...
  3. pmc Safety and immunogenicity of recombinant Rift Valley fever MP-12 vaccine candidates in sheep
    John C Morrill
    Department of Microbiology and Immunology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555 1019, USA
    Vaccine 31:559-65. 2013
    ..The large deletion in the NSm gene may also provide a negative marker that will allow serologic differentiation of naturally infected animals from vaccinated animals...
  4. doi request reprint Mucosal immunization of rhesus macaques with Rift Valley Fever MP-12 vaccine
    John C Morrill
    Applied Research Division, US Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, USA
    J Infect Dis 204:617-25. 2011
    ..A single inoculation of the RVF MP-12 live attenuated vaccine by the aerosol or intranasal route may provide an alternative route of protective immunization to RVFV in addition to conventional intramuscular injection...
  5. pmc Rapid accumulation of virulent rift valley Fever virus in mice from an attenuated virus carrying a single nucleotide substitution in the m RNA
    John C Morrill
    Department of Microbiology and Immunology, The University of Texas Medical Branch at Galveston, Galveston, Texas, United States of America
    PLoS ONE 5:e9986. 2010
    ..RVFV is transmitted by mosquitoes and causes fever and severe hemorrhagic illness among humans, while in livestock it causes fever and high abortion rates...
  6. pmc Genetic subpopulations of Rift Valley fever virus strains ZH548 and MP-12 and recombinant MP-12 strains
    Nandadeva Lokugamage
    Department of Pathology, University of Texas Medical Branch, Galveston, Texas, USA
    J Virol 86:13566-75. 2012
    ..This study provides the first information regarding the genetic subpopulations of RVFV and shows the genetic stability of the MP-12 vaccine manufactured in MRC-5 cells...
  7. doi request reprint Development of a novel, single-cycle replicable rift valley Fever vaccine
    Shin Murakami
    Department of Microbiology and Immunology, The University of Texas Medical Branch, Galveston, Texas, United States of America
    PLoS Negl Trop Dis 8:e2746. 2014
    ..These data demonstrated that scMP-12 is a safe and immunogenic RVFV vaccine candidate. ..