Michael Moritz

Summary

Grants:

Publications

  1. ncbi request reprint Prevention of hospital-acquired hyponatremia: do we have the answers?
    Michael L Moritz
    Division of Nephrology, Children s Hospital of Pittsburgh of UPMC, One Children s Hospital Drive, 4401 Penn Ave, Pittsburgh, PA 15224
    Pediatrics 128:980-3. 2011
  2. ncbi request reprint Can the routine administration of hypotonic parenteral fluids be justified?
    Michael L Moritz
    Clin Pediatr (Phila) 47:725. 2008
  3. doi request reprint Refractory hypercalcemia in an infant secondary to talc pleurodesis resolving after renal transplantation
    S J Aujla
    Division of Pulmonary Medicine, Allergy and Immunology, Department of Pediatrics, Children s Hospital of Pittsburgh, The University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Am J Transplant 8:1329-33. 2008
  4. doi request reprint Urine sodium composition in ambulatory healthy children: hypotonic or isotonic?
    Michael L Moritz
    Division of Nephrology, Children s Hospital of Pittsburgh, The University of Pittsburgh School of Medicine, Pittsburgh, PA 15213 2538, USA
    Pediatr Nephrol 23:955-7. 2008
  5. pmc Alemtuzumab pre-conditioning with tacrolimus monotherapy in pediatric renal transplantation
    R Shapiro
    University of Pittsburgh Thomas E Starzl Transpl Institute Surgery Division of Transplantation, Pittsburgh, PA, USA
    Am J Transplant 7:2736-8. 2007
  6. ncbi request reprint The syndrome of inappropriate antidiuresis
    Michael L Moritz
    N Engl J Med 357:942; author reply 942. 2007
  7. ncbi request reprint Hospital-acquired hyponatremia--why are hypotonic parenteral fluids still being used?
    Michael L Moritz
    Division of Nephrology, Children s Hospital of Pittsburgh, Pittsburgh, PA 15217, USA
    Nat Clin Pract Nephrol 3:374-82. 2007
  8. ncbi request reprint Errors in diagnosing salt poisoning in children
    Michael L Moritz
    Pediatr Emerg Care 23:280. 2007
  9. ncbi request reprint Fluid replacement for severe hyponatremia
    Michael L Moritz
    JAMA 297:41; author reply 41-2. 2007
  10. ncbi request reprint Acute post-streptococcal glomerulonephritis in a 14-month-old boy: why is this uncommon?
    Michael A Bingler
    Department of Pediatrics, Children s Hospital of Pittsburgh, The University of Pittsburgh School of Medicine, Pittsburgh, PA 15213 2538, USA
    Pediatr Nephrol 22:448-50. 2007

Collaborators

Detail Information

Publications55

  1. ncbi request reprint Prevention of hospital-acquired hyponatremia: do we have the answers?
    Michael L Moritz
    Division of Nephrology, Children s Hospital of Pittsburgh of UPMC, One Children s Hospital Drive, 4401 Penn Ave, Pittsburgh, PA 15224
    Pediatrics 128:980-3. 2011
  2. ncbi request reprint Can the routine administration of hypotonic parenteral fluids be justified?
    Michael L Moritz
    Clin Pediatr (Phila) 47:725. 2008
  3. doi request reprint Refractory hypercalcemia in an infant secondary to talc pleurodesis resolving after renal transplantation
    S J Aujla
    Division of Pulmonary Medicine, Allergy and Immunology, Department of Pediatrics, Children s Hospital of Pittsburgh, The University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Am J Transplant 8:1329-33. 2008
    ....
  4. doi request reprint Urine sodium composition in ambulatory healthy children: hypotonic or isotonic?
    Michael L Moritz
    Division of Nephrology, Children s Hospital of Pittsburgh, The University of Pittsburgh School of Medicine, Pittsburgh, PA 15213 2538, USA
    Pediatr Nephrol 23:955-7. 2008
    ..9+/-0.4 ml/kg per hour. It was concluded that healthy children generate free water via the excretion ofa hypertonic urine. It is unlikely that 0.9% NaCl would result in hypernatremia when administered in parenteral fluids...
  5. pmc Alemtuzumab pre-conditioning with tacrolimus monotherapy in pediatric renal transplantation
    R Shapiro
    University of Pittsburgh Thomas E Starzl Transpl Institute Surgery Division of Transplantation, Pittsburgh, PA, USA
    Am J Transplant 7:2736-8. 2007
    ..7%. Although more follow-up is clearly needed, antibody pre-conditioning with alemtuzumab and tacrolimus monotherapy may be a safe and effective regimen in pediatric renal transplantation...
  6. ncbi request reprint The syndrome of inappropriate antidiuresis
    Michael L Moritz
    N Engl J Med 357:942; author reply 942. 2007
  7. ncbi request reprint Hospital-acquired hyponatremia--why are hypotonic parenteral fluids still being used?
    Michael L Moritz
    Division of Nephrology, Children s Hospital of Pittsburgh, Pittsburgh, PA 15217, USA
    Nat Clin Pract Nephrol 3:374-82. 2007
    ....
  8. ncbi request reprint Errors in diagnosing salt poisoning in children
    Michael L Moritz
    Pediatr Emerg Care 23:280. 2007
  9. ncbi request reprint Fluid replacement for severe hyponatremia
    Michael L Moritz
    JAMA 297:41; author reply 41-2. 2007
  10. ncbi request reprint Acute post-streptococcal glomerulonephritis in a 14-month-old boy: why is this uncommon?
    Michael A Bingler
    Department of Pediatrics, Children s Hospital of Pittsburgh, The University of Pittsburgh School of Medicine, Pittsburgh, PA 15213 2538, USA
    Pediatr Nephrol 22:448-50. 2007
    ..We review the literature of both GAS and APSGN and discuss the pathogenesis and epidemiologic reasons for this association...
  11. ncbi request reprint Acute renal failure from xanthine nephropathy during management of acute leukemia
    Christopher LaRosa
    Department of Pediatrics, Children s Hospital of Pittsburgh, Pittsburgh, PA, USA
    Pediatr Nephrol 22:132-5. 2007
    ..Urine measurements for xanthine could aid in the diagnosis of patients with nephrolithiasis complicating tumor lysis syndrome. Allopurinal dosage should be reduced or discontinued if xanthine nephropathy is suspected...
  12. ncbi request reprint Re: Randomized controlled trial of fluid supplementation in term neonates with severe hyperbilirubinemia
    Michael L Moritz
    J Pediatr 149:581; author reply 581-2. 2006
  13. ncbi request reprint 0.9% saline solution for the prevention of hospital-acquired hyponatremia: why is there still doubt?
    Michael L Moritz
    J Pediatr 153:444; author reply 444-6; discussion 446-7. 2008
  14. ncbi request reprint Exercise-associated hyponatremia: why are athletes still dying?
    Michael L Moritz
    Clin J Sport Med 18:379-81. 2008
  15. ncbi request reprint Exercise-associated hyponatremia masquerading as acute mountain sickness: are we missing the diagnosis?
    Juan Carlos Ayus
    Clin J Sport Med 18:383-6. 2008
  16. doi request reprint Postoperative hyponatremia following calvarial vault remodeling in craniosynostosis
    Franklyn P Cladis
    The University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Paediatr Anaesth 21:1020-5. 2011
    ..The incidence, severity, and risk factors for the development of hyponatremia in patients undergoing craniosynostosis surgery are not well known...
  17. doi request reprint Intravenous fluid management for the acutely ill child
    Michael L Moritz
    Division of Nephrology, Department of Pediatrics, Children s Hospital of Pittsburgh of UPMC, The University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15224, USA
    Curr Opin Pediatr 23:186-93. 2011
    ..To review the principles of prescribing intravenous fluids (IVFs) to the acutely ill child and of adjusting sodium composition and fluid rate to prevent disorders in serum sodium or volume status from occurring...
  18. pmc Discovering knowledge on pediatric fluid therapy and dysnatremias from quantitative data found in electronic medical records
    Steve L Pham
    University of Pittsburgh School of Medicine, Pittsburgh, PA
    AMIA Annu Symp Proc 2010:652-6. 2010
    ..This demonstrates that EMR data that can be readily analyzed to discover epidemiologic and predictive knowledge...
  19. doi request reprint The relationship between arginine vasopressin levels and hyponatremia following a percutaneous renal biopsy in children receiving hypotonic or isotonic intravenous fluids
    Kyoko Kanda
    Department of Pediatrics, Kobe University Graduate School of Medicine, Kobe, Japan
    Pediatr Nephrol 26:99-104. 2011
    ..In conclusion, elevated AVP levels were common among our patients following a percutaneous renal biopsy. Isotonic fluids prevented a fall in serum sodium and hyponatremia, while hypotonic fluids did not...
  20. ncbi request reprint Improving intravenous fluid therapy in children with gastroenteritis
    Michael L Moritz
    Pediatr Nephrol 25:1383-4. 2010
    ..0.9% NaCl not only serves as prophylaxis against hyponatremia, but it is superior to hypotonic fluids as an extracellular volume expander and corrects the volume deficit more rapidly...
  21. doi request reprint 100 cc 3% sodium chloride bolus: a novel treatment for hyponatremic encephalopathy
    Michael L Moritz
    Division of Nephrology, Department of Pediatrics, Children s Hospital of Pittsburgh of UPMC, The University of Pittsburgh School of Medicine, One Children s Hospital Drive, 4401 Penn Ave, Pittsburgh, PA 15224, USA
    Metab Brain Dis 25:91-6. 2010
    ..The approach results in a controlled and immediate rise in serum sodium with little risk of inadvertent overcorrection...
  22. ncbi request reprint Bone disease as a new complication of hyponatremia: moving beyond brain injury
    Juan Carlos Ayus
    Clin J Am Soc Nephrol 5:167-8. 2010
  23. ncbi request reprint Water water everywhere: standardizing postoperative fluid therapy with 0.9% normal saline
    Michael L Moritz
    Anesth Analg 110:293-5. 2010
  24. ncbi request reprint Hyponatremia in preterm neonates: not a benign condition
    Michael L Moritz
    Division of Nephrology, Department of Pediatrics, Children s Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15201, USA
    Pediatrics 124:e1014-6. 2009
  25. ncbi request reprint Isotonic maintenance fluids do not produce hypernatraemia
    M L Moritz
    Arch Dis Child 94:170. 2009
  26. doi request reprint Pediatric living donor kidney transplantation under alemtuzumab pretreatment and tacrolimus monotherapy: 4-year experience
    Henkie P Tan
    the Thomas E Starzl Transplantation Institute, University of Pittsburgh Medical Center, Children s Hospital of Pittsburgh, Pittsburgh, PA 15213, USA
    Transplantation 86:1725-31. 2008
    ..Alemtuzumab has been used in off-label studies of solid organ transplantation...
  27. ncbi request reprint Case 8-2006: a woman with Crohn's disease and altered mental status
    Michael L Moritz
    N Engl J Med 354:2833-4; author reply 2834. 2006
  28. pmc Antilymphoid antibody preconditioning and tacrolimus monotherapy for pediatric kidney transplantation
    Ron Shapiro
    Thomas E Starzl Transplantation Institute, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Pediatr 148:813-8. 2006
    ....
  29. ncbi request reprint Bilateral laparoscopic transperitoneal nephrectomy with early peritoneal dialysis in an infant with the nephrotic syndrome
    Zachary V Zuniga
    Department of Pediatric Urology, University of Pittsburgh School of Medicine, 4A424 Desoto Wing, Children s Hospital of Pittsburgh, Pittsburgh, PA 15213, USA
    J Urol 170:1962. 2003
  30. ncbi request reprint Long-term antiproteinuric and renoprotective efficacy and safety of losartan in children with proteinuria
    Demetrius Ellis
    Division of Pediatric Nephrology, Children s Hospital of Pittsburgh and Department of Family Medicine and Clinical Epidemiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Pediatr 143:89-97. 2003
    ..As a consequence, such agents retard progressive renal dysfunction in adults with chronic proteinuria. Long-term efficacy and tolerability data in children are unavailable...
  31. ncbi request reprint Prevention of hospital-acquired hyponatremia: a case for using isotonic saline
    Michael L Moritz
    Division of Nephrology, Department of Pediatrics, Children s Hospital of Pittsburgh, University of Pittsburgh School Medicine, Pittsburgh, Pennsylvania 15213 2538, USA
    Pediatrics 111:227-30. 2003
    ..The current standard of care in pediatrics is to administer hypotonic saline in maintenance parenteral fluids. The safety of this approach has never been evaluated...
  32. ncbi request reprint Quantitative viral load monitoring and cidofovir therapy for the management of BK virus-associated nephropathy in children and adults
    Abhay Vats
    Department of Pediatrics, Children s Hospital of Pittsburgh, Pittsburgh, PA 15213, USA
    Transplantation 75:105-12. 2003
    ..BK virus (BKV)-associated nephropathy (BKVAN) has been increasingly recognized as an important cause of renal transplant dysfunction. We report the role of quantitative viral load monitoring in the management of BKVAN...
  33. ncbi request reprint Systemic anticoagulation and bleeding in children with hemodialysis catheters
    Michael L Moritz
    Department of Pediatrics, Division of Nephrology, Children s Hospital of Pittsburgh, University of Pittsburg School of Medicine, Pennsylvania, USA
    Pediatr Nephrol 18:68-70. 2003
    ..Guidelines are presented to prevent hemorrhagic complications from inadvertent systemic anticoagulation...
  34. ncbi request reprint Disorders of water metabolism in children: hyponatremia and hypernatremia
    Michael L Moritz
    Children s Hospital of Pittsburgh, Pittsburgh, PA, USA
    Pediatr Rev 23:371-80. 2002
  35. ncbi request reprint Survival with hypopituitarism from congenital syphilis
    Dawn Nolt
    University of Pittsburgh School of Medicine, Division of Allergy, Immunology and Infectious Diseases, Children s Hospital of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Pediatrics 109:e63. 2002
    ..Institution of routine testing in all countries might have prevented the severe manifestations of syphilis seen in this child...
  36. ncbi request reprint Acute peritoneal dialysis as both cause and treatment of hypernatremia in an infant
    M L Moritz
    Department of Pediatrics, Albert Einstein College of Medicine Montefiore Medical Center, Bronx, New York, USA
    Pediatr Nephrol 16:697-700. 2001
    ..Although peritoneal dialysis can cause hypernatremia, a modified solute concentration in the dialysate can treat the hypernatremia successfully...
  37. ncbi request reprint La Crosse encephalitis in children
    M L Moritz
    N Engl J Med 345:148-9. 2001
  38. ncbi request reprint Plasmapheresis treatment for recurrent focal sclerosis in pediatric renal allografts
    S M Greenstein
    Department of Surgery, Montefiore Medical Center, Bronx, New York 10467, USA
    Pediatr Nephrol 14:1061-5. 2000
    ..The number of plasmapheresis sessions used to achieve remission should be adjusted according to response rather than adhering to a fixed protocol...
  39. ncbi request reprint The changing pattern of hypernatremia in hospitalized children
    M L Moritz
    Department of Pediatrics, Texas Children s Hospital, Baylor College of Medicine, Houston, Texas, USA
    Pediatrics 104:435-9. 1999
    ..The purpose of this study was to evaluate the current pattern of hypernatremia in hospitalized children...
  40. ncbi request reprint The pathophysiology and treatment of hyponatraemic encephalopathy: an update
    Michael L Moritz
    Division of Nephrology, Department of Pediatrics, Children s Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA
    Nephrol Dial Transplant 18:2486-91. 2003
  41. ncbi request reprint Hospital-acquired hyponatremia: why are there still deaths?
    Michael L Moritz
    Division of Nephrology, Department of Pediatrics, Children s Hospital of Pittsburgh, University of Pittsburgh School Medicine, Pittsburgh, PA 15213 2538, USA
    Pediatrics 113:1395-6. 2004
  42. ncbi request reprint Dysnatremias in the critical care setting
    Michael L Moritz
    Division of Nephrology, Department of Pediatrics, Children s Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Contrib Nephrol 144:132-57. 2004
  43. ncbi request reprint Sirolimus rescue for tacrolimus-associated post-transplant autoimmune hemolytic anemia
    Rudolph P Valentini
    Division of Nephrology, The Carman and Ann Adams Department of Pediatrics, Children s Hospital of Michigan, Detroit, MI 48201 2196, USA
    Pediatr Transplant 10:358-61. 2006
    ..Nearly 3 wk into his illness, tacrolimus was changed to cyclosporine, and then to sirolimus, and resulted in a prompt response. He currently has a normal renal function and a normal hemoglobin level on sirolimus monotherapy...
  44. ncbi request reprint Dysnatremias: why are patients still dying?
    Steven G Achinger
    Division of Nephrology, Department of Medicine, University of Texas Health Science Center San Antonio, San Antonio, TX, USA
    South Med J 99:353-62; quiz 363-4. 2006
    ..Case studies in hypernatremia include hypernatremia in the ICU setting and the emerging condition of breastfeeding-associated hypernatremia in infants...
  45. ncbi request reprint A water deprivation test is not indicated in the evaluation of hypernatremia
    Michael L Moritz
    Am J Kidney Dis 46:1150-1; author reply 1151. 2005
  46. ncbi request reprint Breastfeeding-associated hypernatremia: are we missing the diagnosis?
    Michael L Moritz
    Division of Nephrology, Children s Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Pediatrics 116:e343-7. 2005
    ..To assess the incidence and complications of breastfeeding-associated hypernatremic dehydration among hospitalized neonates. Study..
  47. ncbi request reprint Hospital-induced hyponatremia
    Michael L Moritz
    J Pediatr 147:273-4; author reply 274-5. 2005
  48. ncbi request reprint Preventing neurological complications from dysnatremias in children
    Michael L Moritz
    Division of Nephrology, Department of Pediatrics, Children s Hospital of Pittsburgh, The University of Pittsburgh School of Medicine, PA 15213 2538, USA
    Pediatr Nephrol 20:1687-700. 2005
    ..Breastfed infants must be monitored closely for insufficient lactation and receive lactation support. Judicious use of infant formula supplementation may be called for until problems with lactation can be corrected...
  49. ncbi request reprint Hyponatremia in marathon runners
    Juan C Ayus
    N Engl J Med 353:427-8; author reply 427-8. 2005
  50. ncbi request reprint Reducing risks of hospital acquired hyponatremia
    Michael L Moritz
    Pediatr Neurol 33:75; author reply 75-6. 2005
  51. ncbi request reprint Hypotonic fluids should not be used in volume-depleted children
    Michael L Moritz
    Kidney Int 68:409-10. 2005
  52. ncbi request reprint Infantile systemic lupus erythematosus presenting with pulmonary hemorrhage
    James Kreindler
    Division of Pulmonology, Department of Pediatrics, Children s Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pennsylvania, USA
    Pediatr Nephrol 20:522-5. 2005
    ....
  53. ncbi request reprint Antihypertensive and renoprotective efficacy and safety of losartan. A long-term study in children with renal disorders
    Demetrius Ellis
    Division of Pediatric Nephrology, Children s Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Am J Hypertens 17:928-35. 2004
    ..We assessed the long term efficacy and safety of losartan in lowering blood pressure (BP) and in preserving renal function in hypertensive children with chronic renal disorders...
  54. ncbi request reprint Hypernatremia in hospitalized patients
    M L Moritz
    Ann Intern Med 125:860. 1996
  55. pmc New aspects in the pathogenesis, prevention, and treatment of hyponatremic encephalopathy in children
    Michael L Moritz
    Division of Nephrology, Department of Pediatrics, Children s Hospital of Pittsburgh of UPMC, The University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Pediatr Nephrol 25:1225-38. 2010
    ..In this review, we discuss how to recognize patients at risk for inadvertent overcorrection of hyponatremia and what measures should taken to prevent this, including the judicious use of 1-desamino-8d-arginine vasopressin (dDAVP)...