CHET T contact MORITZ

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. pmc Direct control of paralysed muscles by cortical neurons
    Chet T Moritz
    Department of Physiology and Biophysics and Washington National Primate Research Center, University of Washington, Seattle, Washington 98195, USA
    Nature 456:639-42. 2008
  2. ncbi request reprint Human hoppers compensate for simultaneous changes in surface compression and damping
    Chet T Moritz
    Locomotion Laboratory, Department of Integrative Physiology, University of Colorado, Boulder, CO 80309 0354, USA
    J Biomech 39:1030-8. 2006
  3. ncbi request reprint Human hopping on very soft elastic surfaces: implications for muscle pre-stretch and elastic energy storage in locomotion
    Chet T Moritz
    Locomotion Laboratory, Department of Integrative Physiology, University of Colorado, Boulder, CO 80309 0354, USA
    J Exp Biol 208:939-49. 2005
  4. ncbi request reprint Coherence at 16-32 Hz can be caused by short-term synchrony of motor units
    Chet T Moritz
    Department of Integrative Physiology, University of Colorado, Boulder, USA
    J Neurophysiol 94:105-18. 2005
  5. ncbi request reprint Discharge rate variability influences the variation in force fluctuations across the working range of a hand muscle
    Chet T Moritz
    Department of Physiology and Biophysics, Box 357290, University of Colorado, Boulder, USA
    J Neurophysiol 93:2449-59. 2005
  6. ncbi request reprint Forelimb movements and muscle responses evoked by microstimulation of cervical spinal cord in sedated monkeys
    Chet T Moritz
    Department of Physiology and Biophysics, Box 357290, University of Washington School of Medicine, Seattle, WA 98195 7290, USA
    J Neurophysiol 97:110-20. 2007
  7. ncbi request reprint Passive dynamics change leg mechanics for an unexpected surface during human hopping
    Chet T Moritz
    Dept of Integrative Physiology, 354 UCB, Boulder, CO 80309 0354, USA
    J Appl Physiol 97:1313-22. 2004
  8. ncbi request reprint Prolonged muscle vibration increases stretch reflex amplitude, motor unit discharge rate, and force fluctuations in a hand muscle
    Minoru Shinohara
    Dept of Integrative Physiology, Univ of Colorado, Boulder, CO 80309 0354, USA
    J Appl Physiol 99:1835-42. 2005
  9. ncbi request reprint The Neurochip BCI: towards a neural prosthesis for upper limb function
    Andrew Jackson
    Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195, USA
    IEEE Trans Neural Syst Rehabil Eng 14:187-90. 2006
  10. ncbi request reprint Neuromuscular changes for hopping on a range of damped surfaces
    Chet T Moritz
    Locomotion Laboratory, Department of Integrative Physiology, University of Colorado, Boulder, CO 80309 0354, USA
    J Appl Physiol 96:1996-2004. 2004

Detail Information

Publications11

  1. pmc Direct control of paralysed muscles by cortical neurons
    Chet T Moritz
    Department of Physiology and Biophysics and Washington National Primate Research Center, University of Washington, Seattle, Washington 98195, USA
    Nature 456:639-42. 2008
    ..These results are the first demonstration that direct artificial connections between cortical cells and muscles can compensate for interrupted physiological pathways and restore volitional control of movement to paralysed limbs...
  2. ncbi request reprint Human hoppers compensate for simultaneous changes in surface compression and damping
    Chet T Moritz
    Locomotion Laboratory, Department of Integrative Physiology, University of Colorado, Boulder, CO 80309 0354, USA
    J Biomech 39:1030-8. 2006
    ..Runners may use similar strategies on natural energy-dissipating surfaces such as sand, mud and snow...
  3. ncbi request reprint Human hopping on very soft elastic surfaces: implications for muscle pre-stretch and elastic energy storage in locomotion
    Chet T Moritz
    Locomotion Laboratory, Department of Integrative Physiology, University of Colorado, Boulder, CO 80309 0354, USA
    J Exp Biol 208:939-49. 2005
    ..Thus, the extreme adjustment to leg mechanics for very soft surfaces helps maintain normal center of mass dynamics but requires high muscle activation levels due to the loss of the normal extensor muscle stretch-shorten cycle...
  4. ncbi request reprint Coherence at 16-32 Hz can be caused by short-term synchrony of motor units
    Chet T Moritz
    Department of Integrative Physiology, University of Colorado, Boulder, USA
    J Neurophysiol 94:105-18. 2005
    ..Although the in vivo processes that adjust the timing of motor-unit discharges are not fully understood, these results suggest that they may not depend entirely on an oscillatory drive by the CNS...
  5. ncbi request reprint Discharge rate variability influences the variation in force fluctuations across the working range of a hand muscle
    Chet T Moritz
    Department of Physiology and Biophysics, Box 357290, University of Colorado, Boulder, USA
    J Neurophysiol 93:2449-59. 2005
    ..22) at all force levels. These results support the hypothesis that discharge rate variability is a major determinant of the trends in isometric force variability across the working range of a muscle...
  6. ncbi request reprint Forelimb movements and muscle responses evoked by microstimulation of cervical spinal cord in sedated monkeys
    Chet T Moritz
    Department of Physiology and Biophysics, Box 357290, University of Washington School of Medicine, Seattle, WA 98195 7290, USA
    J Neurophysiol 97:110-20. 2007
    ..The absence of a clear somatotopic map of output sites is probably a result of the stimulation of complex mixtures of fibers and cells...
  7. ncbi request reprint Passive dynamics change leg mechanics for an unexpected surface during human hopping
    Chet T Moritz
    Dept of Integrative Physiology, 354 UCB, Boulder, CO 80309 0354, USA
    J Appl Physiol 97:1313-22. 2004
    ..These results show that passive mechanisms alter leg stiffness for unexpected surface changes before muscle EMG changes and may be critical for adjustments to variable terrain encountered during locomotion in the natural world...
  8. ncbi request reprint Prolonged muscle vibration increases stretch reflex amplitude, motor unit discharge rate, and force fluctuations in a hand muscle
    Minoru Shinohara
    Dept of Integrative Physiology, Univ of Colorado, Boulder, CO 80309 0354, USA
    J Appl Physiol 99:1835-42. 2005
    ..These adjustments were necessary to achieve the target force due to the vibration-induced decrease in the force capacity of the muscle...
  9. ncbi request reprint The Neurochip BCI: towards a neural prosthesis for upper limb function
    Andrew Jackson
    Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195, USA
    IEEE Trans Neural Syst Rehabil Eng 14:187-90. 2006
    ..These observations suggest that spinal microstimulation controlled by cortical neurons could help compensate for damaged corticospinal projections...
  10. ncbi request reprint Neuromuscular changes for hopping on a range of damped surfaces
    Chet T Moritz
    Locomotion Laboratory, Department of Integrative Physiology, University of Colorado, Boulder, CO 80309 0354, USA
    J Appl Physiol 96:1996-2004. 2004
    ..Our findings, and those of previous studies of hopping on elastic surfaces, show that the ankle joint is the key determinant of both springlike and actuator-like leg mechanics during hopping in place...
  11. pmc Human hopping on damped surfaces: strategies for adjusting leg mechanics
    Chet T Moritz
    Department of Integrative Physiology, University of Colorado, Boulder, CO 80309 0354, USA
    Proc Biol Sci 270:1741-6. 2003
    ..Conserving the trajectory of the centre of mass by maintaining spring-like mechanics of the leg-surface combination may be an important control strategy for fast-legged locomotion on variable terrain...

Research Grants4

  1. Cortical signals restore functional muscle activation
    CHET MORITZ; Fiscal Year: 2007
    ..The long-term goal of the proposed research is to develop an implantable brain-computer interface capable of bypassing spinal cord lesions and restoring movement to spinal cord injured patients. ..
  2. Combined stem cell transplantation and targeted microstimulation to direct the fo
    CHET T contact MORITZ; Fiscal Year: 2010
    ..Targeted electrical microstimulation will be applied across the injury in order to guide implanted stem cells to make appropriate connections and restore function following injury. ..
  3. Combined stem cell transplantation and targeted microstimulation to direct the fo
    CHET T contact MORITZ; Fiscal Year: 2010
    ..Targeted electrical microstimulation will be applied across the injury in order to guide implanted stem cells to make appropriate connections and restore function following injury. ..