S L Morgan

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. doi request reprint The effect of common artifacts lateral to the spine on bone mineral density in the lumbar spine
    Sarah L Morgan
    Department of Nutrition Sciences, UAB Osteoporosis Prevention and Treatment Clinic, Birmingham, AL 35294 1270, USA
    J Clin Densitom 11:243-9. 2008
  2. doi request reprint Black hole artifacts-a new potential pitfall for DXA accuracy?
    Sarah L Morgan
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294 1270, USA
    J Clin Densitom 11:266-75. 2008
  3. ncbi request reprint Medical foods: products for the management of chronic diseases
    Sarah L Morgan
    Department of Nutrition Sciences, School of Health Related Professions, The University of Alabama at Birmingham, 1530 3rd Avenue South, Birmingham, AL 35294 1270, USA
    Nutr Rev 64:495-501. 2006
  4. ncbi request reprint Nonprogression of vertebral area or bone mineral content on DXA does not predict compression fractures
    Sarah L Morgan
    Osteoporosis Prevention and Treatment Clinic, The University of Alabama at Birmingham, 35294 1270, USA
    J Clin Densitom 9:261-4. 2006
  5. ncbi request reprint Osteoporosis: handy tools for detection, helpful tips for treatment
    Sarah L Morgan
    UAB Osteoporosis Prevention and Treatment Clinic, The University of Alabama at Birmingham, USA
    J Fam Pract 57:311-20. 2008
  6. pmc The safety of flavocoxid, a medical food, in the dietary management of knee osteoarthritis
    Sarah L Morgan
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama 35294 1270, USA
    J Med Food 12:1143-8. 2009
  7. doi request reprint Nutrition and bone: it is more than calcium and vitamin D
    Sarah L Morgan
    Department of Nutrition Sciences and Department of Medicine, The University of Alabama at Birmingham UAB, The UAB Osteoporosis Prevention and Treatment Clinic and Bone Densitometry Service, 354 Learning Resources Center, 1714 9th Avenue South Birmingham, AL 35294 1270, USA
    Womens Health (Lond Engl) 5:727-37. 2009
  8. ncbi request reprint The effect of folic acid and folinic acid supplements on purine metabolism in methotrexate-treated rheumatoid arthritis
    Sarah L Morgan
    University of Alabama at Birmingham, 35294 1270, USA
    Arthritis Rheum 50:3104-11. 2004
  9. ncbi request reprint Effect of methotrexate therapy on bone mineral density and body composition in rat adjuvant arthritis
    Sarah L Morgan
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Rheumatol 31:1693-7. 2004
  10. doi request reprint Distribution of Z-scores in a University cohort with an emphasis on "high" bone mineral density
    Sarah L Morgan
    Osteoporosis Prevention and Treatment Clinic and Bone Densitometry Service, University of Alabama at Birmingham, Birmingham, AL 35294 1270, USA
    J Clin Densitom 13:385-91. 2010

Research Grants

Collaborators

Detail Information

Publications33

  1. doi request reprint The effect of common artifacts lateral to the spine on bone mineral density in the lumbar spine
    Sarah L Morgan
    Department of Nutrition Sciences, UAB Osteoporosis Prevention and Treatment Clinic, Birmingham, AL 35294 1270, USA
    J Clin Densitom 11:243-9. 2008
    ..We conclude that artifacts lateral to the spine, particularly in a low BMD spine, can affect the interpretation of L1-L4 BMD using a Hologic Discovery W scanner with 12.7 software in array mode...
  2. doi request reprint Black hole artifacts-a new potential pitfall for DXA accuracy?
    Sarah L Morgan
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294 1270, USA
    J Clin Densitom 11:266-75. 2008
    ..Attention should be paid to the possibility of black hole artifacts on DXA scans and the effect they may have on spine results. Viewing scans in the single-energy mode can be used to verify the presence of tantalum clips...
  3. ncbi request reprint Medical foods: products for the management of chronic diseases
    Sarah L Morgan
    Department of Nutrition Sciences, School of Health Related Professions, The University of Alabama at Birmingham, 1530 3rd Avenue South, Birmingham, AL 35294 1270, USA
    Nutr Rev 64:495-501. 2006
    ..Newer medical foods are designed to manage hyperhomocysteinemia, pancreatic exocrine insufficiency, inflammatory conditions, cancer cachexia, and other diseases...
  4. ncbi request reprint Nonprogression of vertebral area or bone mineral content on DXA does not predict compression fractures
    Sarah L Morgan
    Osteoporosis Prevention and Treatment Clinic, The University of Alabama at Birmingham, 35294 1270, USA
    J Clin Densitom 9:261-4. 2006
    ..Thirty percent of subjects had lumbar spine scoliosis. The presence of scoliosis was significantly related to a T-score discrepancy at L1-L4...
  5. ncbi request reprint Osteoporosis: handy tools for detection, helpful tips for treatment
    Sarah L Morgan
    UAB Osteoporosis Prevention and Treatment Clinic, The University of Alabama at Birmingham, USA
    J Fam Pract 57:311-20. 2008
  6. pmc The safety of flavocoxid, a medical food, in the dietary management of knee osteoarthritis
    Sarah L Morgan
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama 35294 1270, USA
    J Med Food 12:1143-8. 2009
    ..Thus, flavocoxid is safe when used in a population with "below average" to "moderately above average cardiovascular risk" compared to placebo...
  7. doi request reprint Nutrition and bone: it is more than calcium and vitamin D
    Sarah L Morgan
    Department of Nutrition Sciences and Department of Medicine, The University of Alabama at Birmingham UAB, The UAB Osteoporosis Prevention and Treatment Clinic and Bone Densitometry Service, 354 Learning Resources Center, 1714 9th Avenue South Birmingham, AL 35294 1270, USA
    Womens Health (Lond Engl) 5:727-37. 2009
    ..Future studies should center on whole food and dietary patterns and their relationship to bone metabolism and fracture risk...
  8. ncbi request reprint The effect of folic acid and folinic acid supplements on purine metabolism in methotrexate-treated rheumatoid arthritis
    Sarah L Morgan
    University of Alabama at Birmingham, 35294 1270, USA
    Arthritis Rheum 50:3104-11. 2004
    ..AICA and adenosine are markers for MTX interference with purine metabolism...
  9. ncbi request reprint Effect of methotrexate therapy on bone mineral density and body composition in rat adjuvant arthritis
    Sarah L Morgan
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Rheumatol 31:1693-7. 2004
    ....
  10. doi request reprint Distribution of Z-scores in a University cohort with an emphasis on "high" bone mineral density
    Sarah L Morgan
    Osteoporosis Prevention and Treatment Clinic and Bone Densitometry Service, University of Alabama at Birmingham, Birmingham, AL 35294 1270, USA
    J Clin Densitom 13:385-91. 2010
    ..These data suggest that a high Z-score is common at 1 or more sites. Further research about the criteria for the diagnosis of high BMD is warranted...
  11. ncbi request reprint Folic acid supplementation prevents deficient blood folate levels and hyperhomocysteinemia during longterm, low dose methotrexate therapy for rheumatoid arthritis: implications for cardiovascular disease prevention
    S L Morgan
    Department of Nutrition Sciences, School of Medicine, University of Alabama at Birmingham, USA
    J Rheumatol 25:441-6. 1998
    ..To determine the effect of longterm methotrexate (MTX) therapy and folic acid supplementation on folate nutriture and homocysteine levels in patients with rheumatoid arthritis...
  12. ncbi request reprint Calcium and vitamin D in osteoporosis
    S L Morgan
    Division of Clinical Nutrition and Dietetics, Departments of Nutrition Sciences and Medicine, Schools of Medicine, Health Related Professions, and Dentistry, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Rheum Dis Clin North Am 27:101-30. 2001
    ..Calcium and vitamin D supplementation is an important adjunctive therapy to use together with antiresorptive therapies...
  13. ncbi request reprint Folate supplementation during methotrexate therapy for rheumatoid arthritis
    S L Morgan
    Schools of Health Professions, Medicine, and Dentistry, Birmingham, AL 35294 1270, USA
    Clin Exp Rheumatol 28:S102-9. 2010
    ..The cost of FA supplements is substantially less than the cost of FLN supplements. This article reviews clinical trials related to folate supplementation during MTX therapy for RA...
  14. ncbi request reprint Need for precision studies at individual institutions and assessment of size of regions of interest on serial DXA scans
    Sarah L Morgan
    University of Alabama at Birmingham Osteoporosis Prevention and Treatment Clinic, Birmingham, AL 35294 1270, USA
    J Clin Densitom 6:97-101. 2003
    ..The trochanter may be less useful in monitoring serial changes if area of the region of interest varies widely...
  15. ncbi request reprint MTX affects inflammation and tissue destruction differently in the rat AA model
    S L Morgan
    Department of Nutrition Sciences, University of Alabama at Birmingham, 35294 3360, USA
    J Rheumatol 28:1476-81. 2001
    ..To investigate the dose response relationships of methotrexate (MTX) therapy in rat adjuvant arthritis (AA), an animal model of rheumatoid arthritis (RA)...
  16. doi request reprint Association of the presence of bone bars on radiographs and hip fracture in postmenopausal Caucasian women
    D B Sarver
    University of Alabama School of Medicine, Birmingham, AL, USA
    Clin Radiol 67:840-2. 2012
    ..To determine whether the presence of bone bars (BB) identified on anteroposterior hip radiographs are more prevalent in patients that have had a hip fracture as compared to patients without a fracture...
  17. pmc Racial or ethnic differences in allele frequencies of single-nucleotide polymorphisms in the methylenetetrahydrofolate reductase gene and their influence on response to methotrexate in rheumatoid arthritis
    L B Hughes
    Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, 415 Lyons Harrison Research Building, Birmingham, AL 35294 0007, USA
    Ann Rheum Dis 65:1213-8. 2006
    ..The anti-folate drug methotrexate (MTX) is commonly used to treat rheumatoid arthritis...
  18. ncbi request reprint Homocysteine, B vitamins, and vascular-access thrombosis in patients treated with hemodialysis
    T Tamura
    Department of Nutrition Sciences, University of Alabama at Birmingham, 35294 3360, USA
    Am J Kidney Dis 32:475-81. 1998
    ..All three white patients had Ala/Ala genotype, and 3 in 45 black patients (6.7%) were heterozygotes (Val/Ala)...
  19. pmc Methotrexate and erythro-9-(2-hydroxynon-3-yl) adenine therapy for rat adjuvant arthritis and the effect of methotrexate on in vivo purine metabolism
    Joseph E Baggott
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294 1270, USA
    Eur J Pharm Sci 31:95-101. 2007
    ..Also adenosine accumulation and blockage of adenosine deaminase (i.e., by EHNA) appear to be less critical to MTX efficacy. Increased levels of AICA metabolites may suppress the immune response in rat AA...
  20. pmc Cofactor role for 10-formyldihydrofolic acid
    J E Baggott
    Department of Nutrition Sciences, University of Alabama, Birmingham 35294, USA
    Biochem J 308:1031-6. 1995
    ..1.2.2). The existence in vivo of 10-HCO-H2folate is suggested in mammals by several reports of detectable amounts of radiolabelled 10-HCO-folate in bile and urine after administration of radiolabelled folic acid...
  21. ncbi request reprint Not just calcium and vitamin D: other nutritional considerations in osteoporosis
    Beth Kitchin
    School of Health Professions and UAB Osteoporosis Prevention and Treatment Clinic, The University of Alabama at Birmingham, 354 LRC, 1714 9th Avenue South, Birmingham, AL 35294 1270, USA
    Curr Rheumatol Rep 9:85-92. 2007
    ..Diets high in fruits and vegetables contribute nutrients such as magnesium associated with bone health and may also produce an alkaline environment, reducing calcium excretion and thus improving bone density...
  22. pmc Methotrexate catabolism to 7-hydroxymethotrexate in rheumatoid arthritis alters drug efficacy and retention and is reduced by folic acid supplementation
    Joseph E Baggott
    University of Alabama at Birmingham, Birmingham, AL 35294 1270, USA
    Arthritis Rheum 60:2257-61. 2009
    ..To assess the catabolism of methotrexate (MTX) to 7-hydroxy-MTX (7-OH-MTX) in patients with rheumatoid arthritis as well as the effect of folic acid and folinic acid on this catabolism...
  23. ncbi request reprint The energy cost of adjuvant-induced arthritis in rats
    Tara Goodson
    The University of Alabama at Birmingham, USA
    Arthritis Rheum 48:2979-82. 2003
    ..To test the hypothesis that rats with adjuvant-induced arthritis (AIA) need more metabolic energy to maintain body weight than healthy control rats or rats with AIA treated with methotrexate (MTX)...
  24. ncbi request reprint Zinc status of women with low bone mineral density who receive calcium supplements
    Sarah L Morgan
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Biol Trace Elem Res 110:211-22. 2006
    ..Although limited by the small sample size and short study duration, our data suggest that a daily calcium dose of 1200 mg had no effect on the zinc status of our subjects...
  25. pmc Measurement of erythrocyte methotrexate polyglutamate levels: ready for clinical use in rheumatoid arthritis?
    Maria I Danila
    Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, 1530 3rd Avenue South, 178 SHEL, Birmingham, AL 35294 2182, USA
    Curr Rheumatol Rep 12:342-7. 2010
    ....
  26. doi request reprint The effect of peritoneal dialysate on DXA bone densitometry results in patients with end-stage renal disease
    Merry Lynn Mann
    University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA
    J Clin Densitom 11:532-6. 2008
    ..We recommend that peritoneal dialyzate be removed prior to scanning patients on PD and that densitometry technologists should be observant about the presence of peritoneal dialysate...
  27. ncbi request reprint Evidence for two phenotypes in the metabolism of methotrexate to 7-hydroxymethotrexate in patients with rheumatoid arthritis
    Joseph E Baggott
    University of Alabama at Birmingham, Birmingham, AL, USA
    Arthritis Rheum 52:356-8. 2005
  28. pmc 13C-enrichment at carbons 8 and 2 of uric acid after 13C-labeled folate dose in man
    Joseph E Baggott
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Biochem Biophys Res Commun 361:307-10. 2007
    ..10-HCO-H(2)folate may function in vivo as the predominant substrate for AICAR transformylase in humans...
  29. ncbi request reprint Effect of folic acid supplementation on the efficacy of methotrexate treatment in rheumatoid arthritis: comment on the article by Khanna et al
    Sarah L Morgan
    Arthritis Rheum 54:1708-9; author reply 1709-10. 2006
  30. ncbi request reprint Folic acid supplements are good (not bad) for rheumatoid arthritis patients treated with low-dose methotrexate
    Joseph E Baggott
    Am J Clin Nutr 88:479-80; author reply 480. 2008
  31. doi request reprint Comparing BMD results between two similar DXA systems using the generalized least significant change
    John A Shepherd
    Department of Radiology, University of California at San Francisco, San Francisco, CA 94143 0946, USA
    J Clin Densitom 11:237-42. 2008
    ..A revision of the International Society for Clinical Densitometry's policies for comparing scans from systems of the same technology may be appropriate...
  32. ncbi request reprint Folic acid and folinic acid supplementation during low-dose methotrexate therapy for rheumatoid arthritis: comment on the article by van Ede et al
    Sarah L Morgan
    Arthritis Rheum 46:1413-4. 2002
  33. ncbi request reprint Vitamin K and the prevention of fractures
    Tsunenobu Tamura
    Arch Intern Med 167:94; author reply 94-5. 2007

Research Grants1

  1. Flavocoxid: A Medical Food Therapy for Osteoarthritis
    Sarah Morgan; Fiscal Year: 2004
    ..This innovative compound has commercial potential with its expected efficacy comparable to or exceeding the currently marketed COX inhibitors but with fewer side effects and at a significantly lower cost. ..