DAVID OWEN MORGAN

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Sequential primed kinases create a damage-responsive phosphodegron on Eco1
    Nicholas A Lyons
    Department of Physiology, University of California, San Francisco, San Francisco, California, USA
    Nat Struct Mol Biol 20:194-201. 2013
  2. pmc The D box meets its match
    David O Morgan
    Department of Physiology, University of California, San Francisco, San Francisco, CA 94158, USA
    Mol Cell 50:609-10. 2013
  3. pmc Mechanisms of ubiquitin transfer by the anaphase-promoting complex
    Mary E Matyskiela
    Department of Physiology, University of California, San Francisco, CA 94158, USA
    J Biol 8:92. 2009
  4. ncbi request reprint The hidden rhythms of the dividing cell
    David O Morgan
    Department of Physiology, University of California, San Francisco, CA 94158, USA
    Cell 141:224-6. 2010

Research Grants

  1. STRUCTURE/FUNCTION OF CYCLIN DEPENDENT KINASES
    David Morgan; Fiscal Year: 2002
  2. MOLECULAR CONTROL OF CELL PROLIFERATION
    DAVID OWEN MORGAN; Fiscal Year: 2010

Collaborators

  • Nicholas A Lyons
  • Mary E Matyskiela
  • John R Yates
  • Bryan R Fonslow
  • Jolene K Diedrich
  • Monica C Rodrigo-Brenni

Detail Information

Publications4

  1. pmc Sequential primed kinases create a damage-responsive phosphodegron on Eco1
    Nicholas A Lyons
    Department of Physiology, University of California, San Francisco, San Francisco, California, USA
    Nat Struct Mol Biol 20:194-201. 2013
    ..This elaborate regulatory system, involving three independent kinases and stringent substrate selection by a ubiquitin ligase, enables robust control of cohesion establishment during normal growth and after stress...
  2. pmc The D box meets its match
    David O Morgan
    Department of Physiology, University of California, San Francisco, San Francisco, CA 94158, USA
    Mol Cell 50:609-10. 2013
    ..In this issue of Molecular Cell, He and colleagues (2013) unveil a high-resolution structure of a key regulatory interface in cell-cycle control: the destruction box sequence bound to the anaphase-promoting complex...
  3. pmc Mechanisms of ubiquitin transfer by the anaphase-promoting complex
    Mary E Matyskiela
    Department of Physiology, University of California, San Francisco, CA 94158, USA
    J Biol 8:92. 2009
    ....
  4. ncbi request reprint The hidden rhythms of the dividing cell
    David O Morgan
    Department of Physiology, University of California, San Francisco, CA 94158, USA
    Cell 141:224-6. 2010
    ..Lu and Cross (2010) now propose that cell-cycle events are ordered by a regulatory system in which a master oscillator, based on cyclin-dependent kinases, entrains a series of peripheral oscillators controlling individual events...

Research Grants2

  1. STRUCTURE/FUNCTION OF CYCLIN DEPENDENT KINASES
    David Morgan; Fiscal Year: 2002
    ..The goal in this work will be to achieve a detailed biochemical understanding of the mechanisms by which this complex enzyme is assembled and regulated during mitosis. ..
  2. MOLECULAR CONTROL OF CELL PROLIFERATION
    DAVID OWEN MORGAN; Fiscal Year: 2010
    ..These studies are also likely to illuminate general mechanisms of protein ubiquitination, a regulatory modification of importance throughout cell biology and human disease. ..