Nirit Mor-Vaknin

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. pmc DEK in the synovium of patients with juvenile idiopathic arthritis: characterization of DEK antibodies and posttranslational modification of the DEK autoantigen
    Nirit Mor-Vaknin
    University of Michigan, Ann Arbor, MI 48109 5640, USA
    Arthritis Rheum 63:556-67. 2011
  2. ncbi request reprint p300/CBP-associated factor drives DEK into interchromatin granule clusters
    Joanne Cleary
    Department of Internal Medicine, Division of Infectious Diseases, University of Michigan, Ann Arbor, Michigan 48109 0640, USA
    J Biol Chem 280:31760-7. 2005
  3. pmc The DEK nuclear autoantigen is a secreted chemotactic factor
    Nirit Mor-Vaknin
    Department of Internal Medicine, Division of Infectious Diseases, University of Michigan Medical Center, Ann Arbor, MI 48109 0640, USA
    Mol Cell Biol 26:9484-96. 2006
  4. pmc Murine colitis is mediated by vimentin
    Nirit Mor-Vaknin
    Department of Internal Medicine, Division of Infectious Diseases, University of Michigan, Ann Arbor, MI 48109 5640, USA
    Sci Rep 3:1045. 2013
  5. ncbi request reprint Vimentin is secreted by activated macrophages
    Nirit Mor-Vaknin
    Department of Internal Medicine, Division of Infectious Diseases, University of Michigan Medical Center, Ann Arbor, MI 48109 0640, USA
    Nat Cell Biol 5:59-63. 2003
  6. pmc Intercellular trafficking of the nuclear oncoprotein DEK
    Anjan K Saha
    Department of Internal Medicine, Division of Infectious Diseases, University of Michigan, Ann Arbor, MI 48109, USA
    Proc Natl Acad Sci U S A 110:6847-52. 2013
  7. doi request reprint A44: High Levels of DEK Autoantibodies May Predict Early Flare Following Cessation of Anti-TNF Therapy
    Nirit Mor-Vaknin
    University of Michigan, Ann Arbor, MI
    Arthritis Rheumatol 66:S65-6. 2014
  8. ncbi request reprint Minireview: DEK and gene regulation, oncogenesis and AIDS
    Kajal V Sitwala
    University of Michigan, Department of Internal Medicine, Division of Infectious Diseases, 5220 MSRB III, 1150 West Medical Center Drive, Ann Arbor, MI 48109 0640, USA
    Anticancer Res 23:2155-8. 2003
  9. pmc Leukocytic promotion of prostate cellular proliferation
    Kristy L McDowell
    Department of Urology, University of Michigan, Ann Arbor, Michigan 48109 0944, USA
    Prostate 70:377-89. 2010

Collaborators

Detail Information

Publications9

  1. pmc DEK in the synovium of patients with juvenile idiopathic arthritis: characterization of DEK antibodies and posttranslational modification of the DEK autoantigen
    Nirit Mor-Vaknin
    University of Michigan, Ann Arbor, MI 48109 5640, USA
    Arthritis Rheum 63:556-67. 2011
    ..Since DEK has been identified in the synovial fluid (SF) of patients with JIA, this study was undertaken to investigate how DEK protein and/or autoantibodies may contribute to the pathogenesis of JIA...
  2. ncbi request reprint p300/CBP-associated factor drives DEK into interchromatin granule clusters
    Joanne Cleary
    Department of Internal Medicine, Division of Infectious Diseases, University of Michigan, Ann Arbor, Michigan 48109 0640, USA
    J Biol Chem 280:31760-7. 2005
    ..These findings also suggest that DEK-associated malignancies and autoimmune diseases might be amenable to treatment with agents that alter acetylation...
  3. pmc The DEK nuclear autoantigen is a secreted chemotactic factor
    Nirit Mor-Vaknin
    Department of Internal Medicine, Division of Infectious Diseases, University of Michigan Medical Center, Ann Arbor, MI 48109 0640, USA
    Mol Cell Biol 26:9484-96. 2006
    ..Therefore, the DEK autoantigen, previously described as a strictly nuclear protein, is secreted and can act as an extracellular chemoattractant, suggesting a direct role for DEK in inflammation...
  4. pmc Murine colitis is mediated by vimentin
    Nirit Mor-Vaknin
    Department of Internal Medicine, Division of Infectious Diseases, University of Michigan, Ann Arbor, MI 48109 5640, USA
    Sci Rep 3:1045. 2013
    ..Our results suggest that vimentin impedes bacterial killing and production of ROS, thereby contributing to the pathogenesis of acute colitis...
  5. ncbi request reprint Vimentin is secreted by activated macrophages
    Nirit Mor-Vaknin
    Department of Internal Medicine, Division of Infectious Diseases, University of Michigan Medical Center, Ann Arbor, MI 48109 0640, USA
    Nat Cell Biol 5:59-63. 2003
    ..These data establish that vimentin is secreted by macrophages in response to pro-inflammatory signalling pathways and is probably involved in immune function...
  6. pmc Intercellular trafficking of the nuclear oncoprotein DEK
    Anjan K Saha
    Department of Internal Medicine, Division of Infectious Diseases, University of Michigan, Ann Arbor, MI 48109, USA
    Proc Natl Acad Sci U S A 110:6847-52. 2013
    ..These findings thus unify the extracellular and intracellular activities of DEK, and suggest that this paracrine loop involving DEK plays a role in chromatin biology...
  7. doi request reprint A44: High Levels of DEK Autoantibodies May Predict Early Flare Following Cessation of Anti-TNF Therapy
    Nirit Mor-Vaknin
    University of Michigan, Ann Arbor, MI
    Arthritis Rheumatol 66:S65-6. 2014
    ..Since DEK and DEK autoantibodies can contribute to the development of immune complexes and NET formation we suggest that DEK antibody levels can predict flare with the discontinuation of anti-TNF therapy...
  8. ncbi request reprint Minireview: DEK and gene regulation, oncogenesis and AIDS
    Kajal V Sitwala
    University of Michigan, Department of Internal Medicine, Division of Infectious Diseases, 5220 MSRB III, 1150 West Medical Center Drive, Ann Arbor, MI 48109 0640, USA
    Anticancer Res 23:2155-8. 2003
    ..A brief review summarizing the relationships that exist between the DEK protein and gene regulation, oncogenesis and AIDS...
  9. pmc Leukocytic promotion of prostate cellular proliferation
    Kristy L McDowell
    Department of Urology, University of Michigan, Ann Arbor, Michigan 48109 0944, USA
    Prostate 70:377-89. 2010
    ..Therefore, we hypothesized that leukocytes associated with either acute or chronic inflammation attracted to the prostate consequent to aging or tumorigenesis may promote the abnormal cellular proliferation associated with BPH and PCa...