Robert Y Moore

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint Monoamine neuron innervation of the normal human brain: an 18F-DOPA PET study
    Robert Y Moore
    Division of Neuroscience and MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College, Hammersmith Hospital, DuCane Road, London W12 ONN, UK
    Brain Res 982:137-45. 2003
  2. ncbi request reprint Paraventricular-subparaventricular hypothalamic lesions selectively affect circadian function
    Robert Y Moore
    Department of Neurology, University of Pittsburgh, PA 15213, USA
    Chronobiol Int 19:345-60. 2002
  3. ncbi request reprint Suprachiasmatic nucleus in sleep-wake regulation
    Robert Y Moore
    Departments of Neurology and Neuroscience, University of Pittsburgh, 3471 Fifth Avenue, Pittsburgh, PA 15213, USA
    Sleep Med 8:27-33. 2007
  4. ncbi request reprint Serotonin innervation of the primate suprachiasmatic nucleus
    Robert Y Moore
    Departments of Neurology and Neuroscience, University of Pittsburgh, 3471 Fifth Avenue, Suite 811, Pittsburgh, PA 15213, USA
    Brain Res 1010:169-73. 2004
  5. ncbi request reprint Organization of midbrain dopamine systems and the pathophysiology of Parkinson's disease
    Robert Y Moore
    Departments of Neurology and Neuroscience, University of Pittsburgh, 3471 Fifth Avenue, Suite 811, Pittsburgh, PA 15213, USA
    Parkinsonism Relat Disord 9:S65-71. 2003
  6. doi request reprint The suprachiasmatic nucleus and sleep-wake regulation
    Robert Y Moore
    Department of Neurology and Neuroscience, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Postgrad Med 116:6-9. 2004
  7. pmc Diurnal variation in regional brain glucose metabolism in depression
    Anne Germain
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Biol Psychiatry 62:438-45. 2007
  8. ncbi request reprint Cognitive correlates of alterations in acetylcholinesterase in Alzheimer's disease
    Nicolaas I Bohnen
    Department of Neurology, University of Pittsburgh Medical School, Liliane S Kaufmann Building, Suite 811, 3471 Fifth Avenue, Pittsburgh, PA 15213, USA
    Neurosci Lett 380:127-32. 2005
  9. pmc Selective hyposmia in Parkinson disease: association with hippocampal dopamine activity
    Nicolaas I Bohnen
    Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA
    Neurosci Lett 447:12-6. 2008
  10. doi request reprint Extrastriatal monoamine neuron function in Parkinson's disease: an 18F-dopa PET study
    Robert Y Moore
    Division of Neuroscience and MRC Clinical Sciences Centre, Faculty of Medicine, Cyclotron Building, Imperial College, Hammersmith Hospital, London W12 ONN, UK
    Neurobiol Dis 29:381-90. 2008

Detail Information

Publications23

  1. ncbi request reprint Monoamine neuron innervation of the normal human brain: an 18F-DOPA PET study
    Robert Y Moore
    Division of Neuroscience and MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College, Hammersmith Hospital, DuCane Road, London W12 ONN, UK
    Brain Res 982:137-45. 2003
    ..These data indicate that 18F-DOPA PET can be used with detailed, anatomically based ROIs as a tool for in vivo analysis of regional changes in monoamine neuron systems throughout the brain in Parkinson's disease and other disorders...
  2. ncbi request reprint Paraventricular-subparaventricular hypothalamic lesions selectively affect circadian function
    Robert Y Moore
    Department of Neurology, University of Pittsburgh, PA 15213, USA
    Chronobiol Int 19:345-60. 2002
    ....
  3. ncbi request reprint Suprachiasmatic nucleus in sleep-wake regulation
    Robert Y Moore
    Departments of Neurology and Neuroscience, University of Pittsburgh, 3471 Fifth Avenue, Pittsburgh, PA 15213, USA
    Sleep Med 8:27-33. 2007
    ..In this review, I will summarize our current understanding of the organization and function of the circadian timing system and its role in the regulation of brain mechanisms of sleep and wake...
  4. ncbi request reprint Serotonin innervation of the primate suprachiasmatic nucleus
    Robert Y Moore
    Departments of Neurology and Neuroscience, University of Pittsburgh, 3471 Fifth Avenue, Suite 811, Pittsburgh, PA 15213, USA
    Brain Res 1010:169-73. 2004
    ..We also find a supraependymal plexus of serotonin axons in the third and lateral ventricles of the human and monkey brains that is similar in distribution, but less dense, than the one reported in rodents...
  5. ncbi request reprint Organization of midbrain dopamine systems and the pathophysiology of Parkinson's disease
    Robert Y Moore
    Departments of Neurology and Neuroscience, University of Pittsburgh, 3471 Fifth Avenue, Suite 811, Pittsburgh, PA 15213, USA
    Parkinsonism Relat Disord 9:S65-71. 2003
    ....
  6. doi request reprint The suprachiasmatic nucleus and sleep-wake regulation
    Robert Y Moore
    Department of Neurology and Neuroscience, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Postgrad Med 116:6-9. 2004
    ..A better understanding of the basis for sleep can help treatment and direct research about sleep...
  7. pmc Diurnal variation in regional brain glucose metabolism in depression
    Anne Germain
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Biol Psychiatry 62:438-45. 2007
    ..This study compared diurnal variation in mood and regional cerebral metabolic rate of glucose (rCMRglc) in depressed and healthy subjects...
  8. ncbi request reprint Cognitive correlates of alterations in acetylcholinesterase in Alzheimer's disease
    Nicolaas I Bohnen
    Department of Neurology, University of Pittsburgh Medical School, Liliane S Kaufmann Building, Suite 811, 3471 Fifth Avenue, Pittsburgh, PA 15213, USA
    Neurosci Lett 380:127-32. 2005
    ..Similar findings were present when the analysis was limited to the temporal cortex. Cortical AChE activity is more robustly associated with functions of attention and working memory compared to performance on primary memory tests in AD...
  9. pmc Selective hyposmia in Parkinson disease: association with hippocampal dopamine activity
    Nicolaas I Bohnen
    Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA
    Neurosci Lett 447:12-6. 2008
    ..These findings indicate that mesolimbic dopamine innervation of the hippocampus may be a determinant of selective hyposmia in PD...
  10. doi request reprint Extrastriatal monoamine neuron function in Parkinson's disease: an 18F-dopa PET study
    Robert Y Moore
    Division of Neuroscience and MRC Clinical Sciences Centre, Faculty of Medicine, Cyclotron Building, Imperial College, Hammersmith Hospital, London W12 ONN, UK
    Neurobiol Dis 29:381-90. 2008
    ..The red nucleus, subthalamus, ventral thalamus and pineal gland were also eventually involved. These findings provide a further basis for understanding the complex pathophysiology of PD in vivo and complement pathological studies...
  11. ncbi request reprint Regional brain glucose metabolism during morning and evening wakefulness in humans: preliminary findings
    Daniel J Buysse
    Department of Psychiatry, University of Pittsburgh School of Medicine, University of Pittsburgh Medical Center, Pennsylvania, USA
    Sleep 27:1245-54. 2004
    ..The goal of this pilot study was to examine regional relative brain glucose metabolism during morning and evening wakefulness in healthy humans...
  12. ncbi request reprint Selective hyposmia and nigrostriatal dopaminergic denervation in Parkinson's disease
    Nicolaas I Bohnen
    Dept of Neurology, University of Pittsburgh, Pittsburgh, PA, USA
    J Neurol 254:84-90. 2007
    ..Assessment of selective olfactory deficits may be used as a simplified olfactory screening test in the evaluation of subjects with possible PD...
  13. doi request reprint In vivo assessment of brain monoamine systems in parkin gene carriers: a PET study
    Nicola Pavese
    MRC Clinical Science Centre and Division of Neuroscience and Mental Health, Imperial College, London, UK
    Exp Neurol 222:120-4. 2010
    ..These findings suggest that parkin patients and IPD patients with similar striatal dysfunction have different patterns of monoaminergic involvement, with more widespread dysfunction in IPD...
  14. ncbi request reprint Plasticity of the nigropallidal pathway in Parkinson's disease
    Alan L Whone
    Division of Neuroscience and MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College, Hammersmith Hospital, London, United Kingdom
    Ann Neurol 53:206-13. 2003
    ....
  15. ncbi request reprint Cortical cholinergic function is more severely affected in parkinsonian dementia than in Alzheimer disease: an in vivo positron emission tomographic study
    Nicolaas I Bohnen
    Departments of Neurology and Radiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Arch Neurol 60:1745-8. 2003
    ..We hypothesized that patients with PDem would have cholinergic deficits that were similar to or greater than those of patients with AD...
  16. ncbi request reprint Lesions of suprachiasmatic nucleus efferents selectively affect rest-activity rhythm
    Eric E Abrahamson
    Departments of Neurology and Neuroscience, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Mol Cell Endocrinol 252:46-56. 2006
    ..J. Neurosci. 23:10691-10702), these data support the view that the SPVZ is the principal relay nucleus for SCN signals to the multiple posterior hypothalamic arousal systems involved in generation of the R-A rhythm...
  17. ncbi request reprint Suprachiasmatic nucleus organization
    Robert Y Moore
    Department of Neurology, University of Pittsburgh, 3471 Fifth Ave, Suite 811, Pittsburgh, PA 15213, USA
    Cell Tissue Res 309:89-98. 2002
    ....
  18. pmc Basal forebrain atrophy is a presymptomatic marker for Alzheimer's disease
    Andrew M Hall
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Alzheimers Dement 4:271-9. 2008
    ....
  19. pmc Innervation of ventricular and periventricular brain compartments
    Rehana K Leak
    Division of Pharmaceutical Sciences, Mylan School of Pharmacy, Duquesne University, Pittsburgh, PA 15282, USA
    Brain Res 1463:51-62. 2012
    ..These observations support the view that ventricular CSF is a significant channel for volume transmission and identifies those brain regions most likely to be involved in this process...
  20. doi request reprint Gamma Knife thalamotomy for essential tremor
    Douglas Kondziolka
    Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Neurosurg 108:111-7. 2008
    ..The purpose of this study was to evaluate the results following Gamma Knife thalamotomy (GKT) for medically refractory essential tremor in a series of patients in whom open surgical techniques were not desirable...
  21. ncbi request reprint Human regional cerebral glucose metabolism during non-rapid eye movement sleep in relation to waking
    Eric A Nofzinger
    Department of Psychiatry, University of Pittsburgh School of Medicine, PA 15213 2593, USA
    Brain 125:1105-15. 2002
    ....
  22. pmc Grooved pegboard test as a biomarker of nigrostriatal denervation in Parkinson's disease
    Nicolaas I Bohnen
    Department of Radiology, University of Michigan, Ann Arbor, MI 48109 0028, USA
    Neurosci Lett 424:185-9. 2007
    ..These findings indicate that there is both a statistical "floor" and "ceiling" effect for the most affected striatal and body sides that must be considered when employing imaging as an outcome measure in clinical trials in PD...
  23. ncbi request reprint Pattern of hypocretin (orexin) soma and axon loss, and gliosis, in human narcolepsy
    Thomas C Thannickal
    Department of Psychiatry and Brain Research Institute, University of California, Los Angeles and Neurobiology Research, VA Greater Los Angeles Healthcare System, North Hills, Calif 91343, USA
    Brain Pathol 13:340-51. 2003
    ....