Christopher P Montgomery

Summary

Affiliation: University of Chicago
Country: USA

Publications

  1. ncbi request reprint Clinical malaria and sickle cell disease among multiple family members in Chicago, Illinois
    Daniel Glikman
    University of Chicago, Department of Pediatrics, Section of Infectious Diseases, MC 6054, 5841 S Maryland Ave, Chicago, IL 60637, USA
    Pediatrics 120:e745-8. 2007
  2. pmc Local inflammation exacerbates the severity of Staphylococcus aureus skin infection
    Christopher P Montgomery
    Department of Pediatrics, University of Chicago, Chicago, Illinois, USA
    PLoS ONE 8:e69508. 2013
  3. pmc CodY deletion enhances in vivo virulence of community-associated methicillin-resistant Staphylococcus aureus clone USA300
    Christopher P Montgomery
    Section of Critical Care, University of Chicago, Chicago, Illinois, USA
    Infect Immun 80:2382-9. 2012
  4. pmc Importance of the global regulators Agr and SaeRS in the pathogenesis of CA-MRSA USA300 infection
    Christopher P Montgomery
    Section of Critical Care, Department of Pediatrics, University of Chicago, Chicago, Illinois, United States of America
    PLoS ONE 5:e15177. 2010
  5. pmc The arginine catabolic mobile element is not associated with enhanced virulence in experimental invasive disease caused by the community-associated methicillin-resistant Staphylococcus aureus USA300 genetic background
    Christopher P Montgomery
    Department of Pediatrics, Section of Critical Care Medicine, University of Chicago, Chicago, IL 60637, USA
    Infect Immun 77:2650-6. 2009
  6. pmc Transcription of inflammatory genes in the lung after infection with community-associated methicillin-resistant Staphylococcus aureus: a role for panton-valentine leukocidin?
    Christopher P Montgomery
    Section of Critical Care Medicine, Department of Pediatrics, University of Chicago, 5841 S Maryland Ave, MC 1145, Chicago, IL 60637, USA
    Infect Immun 77:2159-67. 2009
  7. doi request reprint Comparison of virulence in community-associated methicillin-resistant Staphylococcus aureus pulsotypes USA300 and USA400 in a rat model of pneumonia
    Christopher P Montgomery
    Department of Pediatrics, Section of Critical Care Medicine, University of Chicago, Illinois 60637, USA
    J Infect Dis 198:561-70. 2008
  8. pmc VraT/YvqF is required for methicillin resistance and activation of the VraSR regulon in Staphylococcus aureus
    Susan Boyle-Vavra
    Department of Pediatrics, University of Chicago, Chicago, Illinois, USA
    Antimicrob Agents Chemother 57:83-95. 2013
  9. ncbi request reprint Staphylococcus aureus sepsis and the Waterhouse-Friderichsen syndrome in children
    Patricia V Adem
    Department of Pathology, University of Chicago, USA
    N Engl J Med 353:1245-51. 2005
  10. pmc Improved oxacillin treatment outcomes in experimental skin and lung infection by a methicillin-resistant Staphylococcus aureus isolate with a vraSR operon deletion
    Dae Sun Jo
    Section of Infectious Diseases, Department of Pediatrics, The University of Chicago, Chicago, IL 60637, USA
    Antimicrob Agents Chemother 55:2818-23. 2011

Detail Information

Publications10

  1. ncbi request reprint Clinical malaria and sickle cell disease among multiple family members in Chicago, Illinois
    Daniel Glikman
    University of Chicago, Department of Pediatrics, Section of Infectious Diseases, MC 6054, 5841 S Maryland Ave, Chicago, IL 60637, USA
    Pediatrics 120:e745-8. 2007
    ..The importance of antimalarial prophylaxis should be communicated to parents of children who are traveling to endemic areas as part of routine child care...
  2. pmc Local inflammation exacerbates the severity of Staphylococcus aureus skin infection
    Christopher P Montgomery
    Department of Pediatrics, University of Chicago, Chicago, Illinois, USA
    PLoS ONE 8:e69508. 2013
    ..Thus, the clinical severity of S. aureus skin infection is driven by the inflammatory response to the bacteria, rather than bacterial burden, in a T cell independent manner. ..
  3. pmc CodY deletion enhances in vivo virulence of community-associated methicillin-resistant Staphylococcus aureus clone USA300
    Christopher P Montgomery
    Section of Critical Care, University of Chicago, Chicago, Illinois, USA
    Infect Immun 80:2382-9. 2012
    ..These results demonstrate that CodY is active in USA300 and that CodY-mediated repression restrains the virulence of USA300...
  4. pmc Importance of the global regulators Agr and SaeRS in the pathogenesis of CA-MRSA USA300 infection
    Christopher P Montgomery
    Section of Critical Care, Department of Pediatrics, University of Chicago, Chicago, Illinois, United States of America
    PLoS ONE 5:e15177. 2010
    ..We conclude that agr and saeRS each independently contribute to the remarkable virulence of USA300, likely by means of their effects on expression of secreted toxins...
  5. pmc The arginine catabolic mobile element is not associated with enhanced virulence in experimental invasive disease caused by the community-associated methicillin-resistant Staphylococcus aureus USA300 genetic background
    Christopher P Montgomery
    Department of Pediatrics, Section of Critical Care Medicine, University of Chicago, Chicago, IL 60637, USA
    Infect Immun 77:2650-6. 2009
    ..Nor was the presence of ACME associated with increased dermonecrosis in a model of skin infection. We conclude that ACME is not necessary for virulence in rodent models of CA-MRSA USA300 pneumonia or skin infection...
  6. pmc Transcription of inflammatory genes in the lung after infection with community-associated methicillin-resistant Staphylococcus aureus: a role for panton-valentine leukocidin?
    Christopher P Montgomery
    Section of Critical Care Medicine, Department of Pediatrics, University of Chicago, 5841 S Maryland Ave, MC 1145, Chicago, IL 60637, USA
    Infect Immun 77:2159-67. 2009
    ..Deletion of lukSF-PV did not alter the early immune response to CA-MRSA in the lung...
  7. doi request reprint Comparison of virulence in community-associated methicillin-resistant Staphylococcus aureus pulsotypes USA300 and USA400 in a rat model of pneumonia
    Christopher P Montgomery
    Department of Pediatrics, Section of Critical Care Medicine, University of Chicago, Illinois 60637, USA
    J Infect Dis 198:561-70. 2008
    ..The explanation for this shift is unclear. We hypothesized that USA300 must be more pathogenic--specifically, that USA300 would have increased virulence when compared with USA400 in an animal model...
  8. pmc VraT/YvqF is required for methicillin resistance and activation of the VraSR regulon in Staphylococcus aureus
    Susan Boyle-Vavra
    Department of Pediatrics, University of Chicago, Chicago, Illinois, USA
    Antimicrob Agents Chemother 57:83-95. 2013
    ..aureus. We also provide the first in vivo proof of principle for using VraT as a sole target to resensitize MRSA to β-lactams...
  9. ncbi request reprint Staphylococcus aureus sepsis and the Waterhouse-Friderichsen syndrome in children
    Patricia V Adem
    Department of Pathology, University of Chicago, USA
    N Engl J Med 353:1245-51. 2005
    ..aureus, one susceptible to methicillin and two resistant to methicillin, underscores the close relationship between virulent methicillin-susceptible S. aureus and methicillin-resistant S. aureus isolates now circulating in the community...
  10. pmc Improved oxacillin treatment outcomes in experimental skin and lung infection by a methicillin-resistant Staphylococcus aureus isolate with a vraSR operon deletion
    Dae Sun Jo
    Section of Infectious Diseases, Department of Pediatrics, The University of Chicago, Chicago, IL 60637, USA
    Antimicrob Agents Chemother 55:2818-23. 2011
    ..These findings provide proof-of-principle for development of a new antibiotic that could restore the usefulness of oxacillin against MRSA by inhibiting VraS or VraR...