Babak Mokhlesi

Summary

Affiliation: University of Chicago
Country: USA

Publications

  1. ncbi request reprint Obesity hypoventilation syndrome: prevalence and predictors in patients with obstructive sleep apnea
    Babak Mokhlesi
    Sleep Disorders Center, Section of Pulmonary and Critical Care Medicine, The University of Chicago Pritzker School of Medicine, 5841 S Maryland Ave L11B, Chicago, IL 60637, USA
    Sleep Breath 11:117-24. 2007
  2. ncbi request reprint False-positive FDG-PET scan secondary to lipoid pneumonia mimicking a solid pulmonary nodule
    Babak Mokhlesi
    The University of Chicago Hospitals, 5841 S Maryland Avenue, MC 0999 Room L 11B, Chicago, IL 60637, USA
    Ann Nucl Med 21:411-4. 2007
  3. ncbi request reprint Recent advances in obesity hypoventilation syndrome
    Babak Mokhlesi
    Section of Pulmonary and Critical Care Medicine, The University of Chicago Pritzker School of Medicine, 5841 S Maryland Ave, MC 0999 Room L11B, Chicago, IL 60637, USA
    Chest 132:1322-36. 2007
  4. ncbi request reprint Predicting extubation failure after successful completion of a spontaneous breathing trial
    Babak Mokhlesi
    Section of Pulmonary and Critical Care Medicine, University of Chicago Pritzker School of Medicine, Chicago IL 60637, USA
    Respir Care 52:1710-7. 2007
  5. pmc Assessment and management of patients with obesity hypoventilation syndrome
    Babak Mokhlesi
    Section of Pulmonary and Critical Care Medicine, and Sleep Disorders Center, University of Chicago Pritzker School of Medicine, Chicago, IL 60637, USA
    Proc Am Thorac Soc 5:218-25. 2008
  6. doi request reprint Association of obstructive sleep apnea in rapid eye movement sleep with reduced glycemic control in type 2 diabetes: therapeutic implications
    Daniela Grimaldi
    Corresponding author Babak Mokhlesi
    Diabetes Care 37:355-63. 2014
  7. pmc Sleep-disordered breathing and postoperative outcomes after bariatric surgery: analysis of the nationwide inpatient sample
    Babak Mokhlesi
    Sleep Disorders Center and the Section of Pulmonary and Critical Care, Department of Medicine, The University of Chicago, 5841 S Maryland Ave MC6076, Chicago, IL, 60637, USA
    Obes Surg 23:1842-51. 2013
  8. ncbi request reprint Obesity hypoventilation syndrome: a state-of-the-art review
    Babak Mokhlesi
    Section of Pulmonary and Critical Care Medicine, University of Chicago Pritzker School of Medicine, Chicago IL 60637, USA
    Respir Care 55:1347-62; discussion 1363-5. 2010
  9. pmc Impact of adherence with positive airway pressure therapy on hypercapnia in obstructive sleep apnea
    Babak Mokhlesi
    Division of Pulmonary and Critical Care Medicine, Cook County Hospital and Rush University Medical Center, 1901 West Harrison Street, Clinic T, Suite 2818 B, Chicago, IL 60612, USA
    J Clin Sleep Med 2:57-62. 2006
  10. doi request reprint Prevalence, clinical features, and CPAP adherence in REM-related sleep-disordered breathing: a cross-sectional analysis of a large clinical population
    Walter Conwell
    Department of Medicine, University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, USA
    Sleep Breath 16:519-26. 2012

Detail Information

Publications32

  1. ncbi request reprint Obesity hypoventilation syndrome: prevalence and predictors in patients with obstructive sleep apnea
    Babak Mokhlesi
    Sleep Disorders Center, Section of Pulmonary and Critical Care Medicine, The University of Chicago Pritzker School of Medicine, 5841 S Maryland Ave L11B, Chicago, IL 60637, USA
    Sleep Breath 11:117-24. 2007
    ..In conclusion, OHS is common in severe OSA. A normal serum bicarbonate level excludes hypercapnia and an elevated serum bicarbonate level should prompt clinicians to measure arterial blood gases...
  2. ncbi request reprint False-positive FDG-PET scan secondary to lipoid pneumonia mimicking a solid pulmonary nodule
    Babak Mokhlesi
    The University of Chicago Hospitals, 5841 S Maryland Avenue, MC 0999 Room L 11B, Chicago, IL 60637, USA
    Ann Nucl Med 21:411-4. 2007
    ..2 suggestive of malignancy. The histology of the lung nodule was consistent with lipoid pneumonia, a benign condition frequently associated with inadvertent aspiration or inhalation of oily substances...
  3. ncbi request reprint Recent advances in obesity hypoventilation syndrome
    Babak Mokhlesi
    Section of Pulmonary and Critical Care Medicine, The University of Chicago Pritzker School of Medicine, 5841 S Maryland Ave, MC 0999 Room L11B, Chicago, IL 60637, USA
    Chest 132:1322-36. 2007
    ..In this review, we will discuss the definition and clinical presentation of OHS, provide a summary of its prevalence, review the current understanding of the pathophysiology, and discuss the recent advances in the therapeutic options...
  4. ncbi request reprint Predicting extubation failure after successful completion of a spontaneous breathing trial
    Babak Mokhlesi
    Section of Pulmonary and Critical Care Medicine, University of Chicago Pritzker School of Medicine, Chicago IL 60637, USA
    Respir Care 52:1710-7. 2007
    ..To derive a clinical prediction rule that uses bedside clinical variables to predict extubation failure (reintubation within 48 h) after a successful spontaneous breathing trial...
  5. pmc Assessment and management of patients with obesity hypoventilation syndrome
    Babak Mokhlesi
    Section of Pulmonary and Critical Care Medicine, and Sleep Disorders Center, University of Chicago Pritzker School of Medicine, Chicago, IL 60637, USA
    Proc Am Thorac Soc 5:218-25. 2008
    ..In this review we define the clinical characteristics of the syndrome and review the pathophysiology, morbidity, and mortality associated with it. Last, we discuss currently available treatment modalities...
  6. doi request reprint Association of obstructive sleep apnea in rapid eye movement sleep with reduced glycemic control in type 2 diabetes: therapeutic implications
    Daniela Grimaldi
    Corresponding author Babak Mokhlesi
    Diabetes Care 37:355-63. 2014
    ..Treatment of OSA is often limited to the first half of the night, when NREM rather than REM sleep predominates. We aimed to quantify the impact of OSA in REM versus NREM sleep on hemoglobin A1c (HbA1c) in subjects with type 2 diabetes...
  7. pmc Sleep-disordered breathing and postoperative outcomes after bariatric surgery: analysis of the nationwide inpatient sample
    Babak Mokhlesi
    Sleep Disorders Center and the Section of Pulmonary and Critical Care, Department of Medicine, The University of Chicago, 5841 S Maryland Ave MC6076, Chicago, IL, 60637, USA
    Obes Surg 23:1842-51. 2013
    ..However, the impact of SDB on postoperative outcomes in patients undergoing bariatric surgery remains less clearly defined. We hypothesized that SDB would be independently associated with worse postoperative outcomes...
  8. ncbi request reprint Obesity hypoventilation syndrome: a state-of-the-art review
    Babak Mokhlesi
    Section of Pulmonary and Critical Care Medicine, University of Chicago Pritzker School of Medicine, Chicago IL 60637, USA
    Respir Care 55:1347-62; discussion 1363-5. 2010
    ..This review will include disease definition and epidemiology, clinical characteristics of the syndrome, pathophysiology, and morbidity and mortality associated with it. Lastly, treatment modalities will be discussed in detail...
  9. pmc Impact of adherence with positive airway pressure therapy on hypercapnia in obstructive sleep apnea
    Babak Mokhlesi
    Division of Pulmonary and Critical Care Medicine, Cook County Hospital and Rush University Medical Center, 1901 West Harrison Street, Clinic T, Suite 2818 B, Chicago, IL 60612, USA
    J Clin Sleep Med 2:57-62. 2006
    ..Our objective was to quantify the effect of adherence with positive airway pressure on hypercapnia and hypoxia in these patients...
  10. doi request reprint Prevalence, clinical features, and CPAP adherence in REM-related sleep-disordered breathing: a cross-sectional analysis of a large clinical population
    Walter Conwell
    Department of Medicine, University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, USA
    Sleep Breath 16:519-26. 2012
    ..We also investigated how frequently CPAP therapy was recommended in patients with REM-related SDB and if they had lower CPAP adherence compared to non-stage-specific SDB...
  11. pmc Risk of obstructive sleep apnea in obese and nonobese women with polycystic ovary syndrome and healthy reproductively normal women
    Babak Mokhlesi
    Sleep Disorders Center, Section of Pulmonary and Critical Care, Department of Medicine, University of Chicago, Chicago, Illinois 60612, USA
    Fertil Steril 97:786-91. 2012
    ..To study the risk for obstructive sleep apnea (OSA) in a group of nonobese and obese polycystic ovary syndrome (PCOS) and control women...
  12. doi request reprint Obstructive sleep apnea and type 2 diabetes: interacting epidemics
    Esra Tasali
    University of Chicago, Department of Medicine, 5841 S Maryland Ave, MC 6026, Chicago, IL 60637, USA
    Chest 133:496-506. 2008
    ..A better understanding of the relationship between OSA and type 2 diabetes may have important public health implications...
  13. doi request reprint The impact of sleep consultation prior to a diagnostic polysomnogram on continuous positive airway pressure adherence
    Sushmita Pamidi
    Sleep Disorders Center, Section of Pulmonary and Critical Medicine, Department of Medicine, 5841 S Maryland Ave, MC 6076 Room M630, Chicago, IL 60637, USA
    Chest 141:51-7. 2012
    ..Polysomnograms (PSGs) are routinely ordered by nonsleep specialists. However, it is unknown whether a sleep specialist consultation prior to a diagnostic PSG influences adherence to continuous positive airway pressure (CPAP) therapy...
  14. doi request reprint Depressive symptoms and obesity as predictors of sleepiness and quality of life in patients with REM-related obstructive sleep apnea: cross-sectional analysis of a large clinical population
    Sushmita Pamidi
    Sleep Disorders Center, Section of Pulmonary and Critical Care, Department of Medicine, University of Chicago, Chicago, IL 60637, USA
    Sleep Med 12:827-31. 2011
    ..We also assessed if these characteristics were predictors of sleepiness and QoL in all patients with OSA (AHI ≥ 5) as well as in non-stage specific OSA...
  15. pmc Predictors of slow-wave sleep in a clinic-based sample
    Babak Mokhlesi
    Department of Medicine, University of Chicago, Chicago, IL 60637, USA
    J Sleep Res 21:170-5. 2012
    ..Future research needs to explore potential reasons for reduced slow-wave sleep in these individuals...
  16. doi request reprint Accuracy and reliability of extubation decisions by intensivists
    Aiman Tulaimat
    Division of Pulmonary and Critical Care Medicine, John H Stroger Jr Hospital of Cook County, Chicago, Illinois 60612, USA
    Respir Care 56:920-7. 2011
    ..Although predictors of extubation failure have been evaluated, physicians' reasoning to extubate a patient has received minimal attention. We hypothesized that the accuracy and reliability of physicians' extubation decisions are low...
  17. doi request reprint Excessive daytime sleepiness and obstructive sleep apnea in patients with sarcoidosis
    Karen C Patterson
    Section of Pulmonary and Critical Care, The University of Chicago, Chicago, IL, USA
    Chest 143:1562-8. 2013
    ..The aim of this study was to assess the relationship between sarcoidosis and EDS...
  18. pmc CPAP adherence in patients with newly diagnosed obstructive sleep apnea prior to elective surgery
    Amy S Guralnick
    Sleep Disorders Center, Section of Pulmonary and Critical Care, Department of Medicine, University of Chicago, Chicago, IL 60637, USA
    J Clin Sleep Med 8:501-6. 2012
    ..However, it remains unclear whether patients diagnosed with OSA in the preoperative period adhere to prescribed CPAP therapy...
  19. doi request reprint Bariatric surgery and its impact on sleep architecture, sleep-disordered breathing, and metabolism
    Silvana Pannain
    Section of Endocrinology, Diabetes and Metabolism, The University of Chicago Pritzker School of Medicine, 5841 S Maryland Avenue, Chicago, IL 60637, USA
    Best Pract Res Clin Endocrinol Metab 24:745-61. 2010
    ..Metabolic disorders and specifically diabetes often improve dramatically early after the procedure, before any significant weight loss has occurred. The modified gastrointestinal anatomy and physiology may explain this phenomenon...
  20. doi request reprint Factors associated with excessive daytime sleepiness in patients with severe obstructive sleep apnea
    John H Jacobsen
    Department of Neurology, University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, USA
    Sleep Breath 17:629-35. 2013
    ..To that end, our goal was to investigate factors associated with EDS based on the Epworth Sleepiness Scale (ESS) score in a large clinical population with severe OSA (apnea-hypopnea index ≥30)...
  21. ncbi request reprint Toxicology in the critically ill patient
    Babak Mokhlesi
    Department of Medicine, Rush Medical College, Division of Pulmonary and Critical Care Medicine, Sleep Laboratory, Cook County Hospital Rush University Medical Center, 1900 West Polk Street, Chicago, IL 60612, USA
    Clin Chest Med 24:689-711. 2003
    ..Despite a paucity of evidence-based information on the management of intoxicated patients, a rational and systematic approach can be life saving...
  22. ncbi request reprint Adult toxicology in critical care: Part II: specific poisonings
    Babak Mokhlesi
    Division of Pulmonary and Critical Care Medicine, Cook County Hospital Rush Medical College, Chicago, IL 60612, USA
    Chest 123:897-922. 2003
  23. ncbi request reprint Street drug abuse leading to critical illness
    Babak Mokhlesi
    Division of Pulmonary and Critical Care, Cook County Hospital and Rush Medical Center, 1901 West Harrison Street, Suite 2818 B, Chicago, IL 60612, USA
    Intensive Care Med 30:1526-36. 2004
    ..In this review article we intend to familiarize critical care physicians with the most common street drugs such as amphetamines, ecstasy, cocaine, gamma hydroxybutyrate, opioids, and phencyclidine...
  24. ncbi request reprint Clinical implications of gastroesophageal reflux disease and swallowing dysfunction in COPD
    Babak Mokhlesi
    Department of Medicine, Cook County Hospital Rush Medical College, Chicago, Illinois 60612, USA
    Am J Respir Med 2:117-21. 2003
    ..Further clinical research is necessary to evaluate the role of GERD and swallowing dysfunction in both stable and acute exacerbation of COPD...
  25. ncbi request reprint Cortisol levels and mortality in severe sepsis
    Susan Sam
    Division of Endocrinology, Metabolism, and Molecular Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Clin Endocrinol (Oxf) 60:29-35. 2004
    ....
  26. pmc A brief survey of patients' first impression after CPAP titration predicts future CPAP adherence: a pilot study
    Jay S Balachandran
    Sleep Disorders Center, Section of Pulmonary and Critical Care, Department of Medicine, Chicago, IL, USA
    J Clin Sleep Med 9:199-205. 2013
    ..We hypothesized that questionnaire responses would independently predict CPAP adherence during the first 30 days of therapy...
  27. doi request reprint Diagnosis and management of obesity hypoventilation syndrome in the ICU
    Won Y Lee
    Section of Pulmonary and Critical Care Medicine, The University of Chicago Pritzker School of Medicine, 5841 South Maryland Avenue, Sleep Disorders Center W 4, Chicago, IL 60637, USA
    Crit Care Clin 24:533-49, vii. 2008
    ..Finally, we offer treatment strategies during ICU management using noninvasive positive pressure ventilation that may guide the physician in the care of these challenging patients...
  28. ncbi request reprint Adult toxicology in critical care: part I: general approach to the intoxicated patient
    Babak Mokhlesi
    Division of Pulmonary and Critical Care Medicine, Cook County Hospital Rush Medical College, Chicago, IL 60612, USA
    Chest 123:577-92. 2003
    ..Specific poisonings will be reviewed in the second section of these review articles...
  29. ncbi request reprint Positive airway pressure titration in obesity hypoventilation syndrome: continuous positive airway pressure or bilevel positive airway pressure
    Babak Mokhlesi
    Chest 131:1624-6. 2007
  30. ncbi request reprint Continuous positive airway pressure in patients with heart failure
    Aiman Tulaimat
    N Engl J Med 349:93-5; author reply 93-5. 2003
  31. ncbi request reprint Noninvasive ventilation for persistent weaning failure
    Aiman Tulaimat
    Am J Respir Crit Care Med 169:1073; author reply 1073-4. 2004
  32. ncbi request reprint Corticosteroids for patients with septic shock
    Babak Mokhlesi
    JAMA 289:43; author reply 43-4. 2003