Research Topics
Species | D C MohrSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Screening for depression among patients with multiple sclerosis: two questions may be enoughD C Mohr
University of California, San Francisco, VAMC, San Francisco, CA 94121, USA
Mult Scler 13:215-9. 2007..This is the first study on the effectiveness of using two questions assessing mood and anhedonia (loss of interest or pleasure) in screening for major depressive disorder (MDD) in MS...- Brain lesion volume and neuropsychological function predict efficacy of treatment for depression in multiple sclerosisDavid C Mohr
Department of Psychiatry and Neurology, University of California, San Francisco, and Veterans Affairs Medical Center, San Francisco, CA, USA
J Consult Clin Psychol 71:1017-24. 2003..22, p=.005), lesion volume in many discrete areas, and neuropsychological functioning (R2=.29, p=.0009). The effect of total lesion volume on 6-month follow-up BDI results was fully mediated by neuropsychological function... 
Association between stressful life events and exacerbation in multiple sclerosis: a meta-analysisDavid C Mohr
Department of Psychiatry, University of California, San Francisco, CA 94142, USA
BMJ 328:731. 2004..To quantify the association between stressful life events and exacerbations of multiple sclerosis...- The relationship between social support, depression and treatment for depression in people with multiple sclerosisD C Mohr
Departments of Psychiatry and Neurology, University of California, San Francisco, USA
Psychol Med 34:533-41. 2004..This study examined the effects of treatment for depression on social support among patients with multiple sclerosis (MS)... - Social support as a buffer in the relationship between treatment for depression and T-cell production of interferon gamma in patients with multiple sclerosisDavid C Mohr
Departments of Psychiatry and Neurology, and VA Medical Center, University of California San Francisco, 4150 Clement Street 116 A, San Francisco, CA 94121, USA
J Psychosom Res 57:155-8. 2004..This study examined the buffering effects of social support on the relationship between depression and autoaggressive immune function in multiple sclerosis (MS)... - Self-injection anxiety training: a treatment for patients unable to self-inject injectable medicationsDavid C Mohr
University of California, San Francisco, CA, USA
Mult Scler 11:182-5. 2005..058). These findings suggest that SIAT is a potentially valuable intervention to teach self-injection skills to injection phobic and anxious patients, and should be investigated more thoroughly in a larger clinical trial... - A preliminary report on a skills-based telephone-administered peer support programme for patients with multiple sclerosisDavid C Mohr
Department of Psychiatry, University of California, San Francisco, CA, USA
Mult Scler 11:222-6. 2005..Peer-support interventions for MS generally provide support but no skills training. The aim of this study was to evaluate a brief telephone-administered skills-training model of peer-support for patients with MS... - A temporal framework for understanding the effects of stressful life events on inflammation in patients with multiple sclerosisDavid C Mohr
Department of Psychiatry and Neurology, University of California, San Francisco, CA 94131, USA
Brain Behav Immun 20:27-36. 2006..These three hypotheses are not necessarily mutually exclusive. Data on psychosocial mediators and moderators are also briefly reviewed and future research directions are discussed... - Telephone-administered psychotherapy for depressionDavid C Mohr
Veterans Administration Medical Center, University of California, San Francisco 94121, USA
Arch Gen Psychiatry 62:1007-14. 2005..No study has examined if the skills-training component to T-CBT provides any benefit beyond that provided by nonspecific factors... - Treatment of depression for patients with multiple sclerosis in neurology clinicsD C Mohr
University of California, Veterans Administration Medical Center, San Francisco 94121, USA
Mult Scler 12:204-8. 2006..The objective of this study was to examine the adequacy of antidepressant pharmacotherapy in a sample of patients with multiple sclerosis (MS) treated by neurologists... - Couples therapy at end of lifeDavid C Mohr
University of California, San Francisco, CA, USA
Psychooncology 12:620-7. 2003..While the size of the study precludes generalizing these findings to a larger population, this study supports further exploration of couples therapy as a potentially useful adjunct to end of life care... - Effects of treatment for depression on fatigue in multiple sclerosisDavid C Mohr
University of California, San Francisco, Veterans Affairs Medical Center, San Francisco, California 94121, USA
Psychosom Med 65:542-7. 2003..The goal of this study was to examine the effects of treatment for depression on fatigue in MS... - The psychosocial impact of multiple sclerosis: exploring the patient's perspectiveD C Mohr
Department of Neurology, University of California, San Francisco 94115 1642, USA
Health Psychol 18:376-82. 1999..These findings indicate that benefit-finding is a substantial and poorly understood part of the illness experience for MS patients... - Course of depression during the initiation of interferon beta-1a treatment for multiple sclerosisD C Mohr
Department of Neurology, University of California, San Francisco, USA
Arch Neurol 56:1263-5. 1999..To examine the hypothesis that increases in depression after initiation of treatment with interferon beta-1a for multiple sclerosis can be explained as representing a return to pretreatment levels of depression... - Telephone-administered cognitive-behavioral therapy for the treatment of depressive symptoms in multiple sclerosisD C Mohr
Department of Neurology, University of California, San Francisco UCSF 94115 1642, USA
J Consult Clin Psychol 68:356-61. 2000..Furthermore, adherence to interferon beta-1a, a disease-modifying medication for the treatment of MS, was significantly better at the 4-month follow-up among patients who received CMS as compared with those in the UCC condition... - Injectable medication for the treatment of multiple sclerosis: the influence of self-efficacy expectations and injection anxiety on adherence and ability to self-injectD C Mohr
University of California, San Francisco, USA
Ann Behav Med 23:125-32. 2001..This relation was mediated by the patient's ability to self-inject. Patients 'experienced level of injection anxiety was related to adherence but not to method of injection... - Treatment of depression is associated with suppression of nonspecific and antigen-specific T(H)1 responses in multiple sclerosisD C Mohr
Department of Psychiatry, University of California, San Francisco, USA
Arch Neurol 58:1081-6. 2001.... - Comparative outcomes for individual cognitive-behavior therapy, supportive-expressive group psychotherapy, and sertraline for the treatment of depression in multiple sclerosisD C Mohr
Department of Neurology, University of California, San Fancisco, USA
J Consult Clin Psychol 69:942-9. 2001..Reasons for this inconsistency are discussed. These findings suggest that CBT or sertraline is more likely to be effective in treating MDD in MS compared with supportive group treatments... - The mediating effects of sleep in the relationship between traumatic stress and health symptoms in urban police officersDavid Mohr
University of California, San Francisco, California, USA
Psychosom Med 65:485-9. 2003..This study explored the hypothesis that the relationship between posttraumatic stress symptoms and health is mediated by sleep problems... - Moderating effects of coping on the relationship between stress and the development of new brain lesions in multiple sclerosisDavid C Mohr
University of California, VAMC, San Francisco, CA 94121, USA
Psychosom Med 64:803-9. 2002..This study examined the hypothesis that coping moderates the subsequent relationship between stress and the development of new brain lesions in MS... - Teaching patients to self-inject: pilot study of a treatment for injection anxiety and phobia in multiple sclerosis patients prescribed injectable medicationsDavid C Mohr
Veterans Administration Medical Ctr, University of California, San Francisco 94131, USA
J Behav Ther Exp Psychiatry 33:39-47. 2002..Seven of the eight patients continued to self-inject at 3-month follow-up. Patients showed significant improvements in self-injection self-efficacy and injection anxiety... - Multiple sclerosis: empirical literature for the clinical health psychologistD C Mohr
University of California, San Francisco
J Clin Psychol 57:479-99. 2001..The types of coping common in MS and their effects on adjustment are discussed. The empirical literature on psychological and neuropsychological intervention is reviewed. The small literature on caregiving in MS is also summarized... - The relationship among depression, subjective cognitive impairment, and neuropsychological performance in multiple sclerosisL Julian
University of California, San Francisco, CA, USA
Mult Scler 13:81-6. 2007..Furthermore, patients may be more accurate reporters of their cognitive impairment after successful treatment for depression, suggesting that depression decreases the accuracy of patient reported cognitive impairment... - Clinical depression versus distress among patients with type 2 diabetes: not just a question of semanticsLawrence Fisher
Department of Family and Community Medicine, Box 0900, University of California San Francisco, San Francisco, CA 94143, USA
Diabetes Care 30:542-8. 2007..We sought to determine differences between structured interviews, symptom questionnaires, and distress measures for assessment of depression in patients with diabetes... - Daily negative mood affects fasting glucose in type 2 diabetesMarilyn M Skaff
Department of Family and Medicine, University of California, San Francisco, CA, USA
Health Psychol 28:265-72. 2009..To examine the relationship between mood and blood glucose in a 21-day daily diary study... - ApoE alleles, depression and positive affect in multiple sclerosisL J Julian
Department of Medicine, University of California San Francisco, San Francisco, CA, USA
Mult Scler 15:311-5. 2009..Depression is common in multiple sclerosis (MS) and the role of ApoE alleles is unknown... - Predictors of posttraumatic stress in police and other first respondersCharles R Marmar
San Francisco Veterans Affairs Medical Center, 4150 Clement St 116 P, San Francisco, CA 94121, USA
Ann N Y Acad Sci 1071:1-18. 2006..Next steps in this line of research will be to test this model prospectively in a sample of 400 police academy recruits assessed during training and currently being followed for the first 2 years of police service... - Stress and multiple sclerosisDavid C Mohr
Dept of Preventive Medicine, Northwestern University, Feinberg School of Medicine, 680 N Lakeshore Drive, Suite 1220, Chicago, IL, 60611, USA
J Neurol 254:II65-8. 2007..It is argued that a purely causal relationship, in which stressful events alone trigger exacerbation, is unlikely. Rather, we propose that stress may be one factor among many that influence risk of exacerbation... - Alliance in two telephone-administered treatments: relationship with depression and health outcomesVictoria Beckner
Department of Psychiatry, University of California, San Francisco, CA 94118, USA
J Consult Clin Psychol 75:508-12. 2007..The findings suggest that the therapist-client relationship is important to improvement in telephone therapy and that the role of alliance in outcome may vary by treatment approach... - Barriers to psychotherapy among depressed and nondepressed primary care patientsDavid C Mohr
University of California, Veterans Administration Medical Center, San Francisco, California, USA
Ann Behav Med 32:254-8. 2006..However, when referrals for psychotherapy are made, only 20% ever follow up, and of these, half drop out of treatment. This suggests that there are substantial barriers to accessing psychotherapy... 
Relationships among depressive symptoms, benefit-finding, optimism, and positive affect in multiple sclerosis patients after psychotherapy for depressionStacey L Hart
Department of Psychiatry, University of California, San Francisco, CA, USA
Health Psychol 27:230-8. 2008....- Reduction in disability in a randomized controlled trial of telephone-administered cognitive-behavioral therapyDavid C Mohr
Department of Psychiatry, University of California, USA
Health Psychol 26:554-63. 2007..This is a secondary analysis of a randomized controlled trial; the primary outcome results for depression are reported in D. C. Mohr, S. L. Hart, L. Julian, C. Catledge, L. Honos-Webb, L. Vella, et al. (2005)... - Therapeutic alliance mediates the relationship between interpersonal problems and depression outcome in a cohort of multiple sclerosis patientsIsa Howard
San Francisco Veteran s Affairs Medical Center, San Francisco, CA 94131, USA
J Clin Psychol 62:1197-204. 2006..The IIP-C significantly predicted Week 16 BDI and the WAI-C at 4 weeks. When controlling for the WAI-C, the relationship between the IIP-C and BDI was no longer significant, supporting the mediational hypothesis... - A meta-analysis of cortisol response to challenge in human aging: importance of genderChristian Otte
Department of Psychiatry, University of California, San Francisco, CA, USA
Psychoneuroendocrinology 30:80-91. 2005..Prospective studies should explore whether the higher cortisol response in the elderly is a risk factor for developing neuropsychiatric and medical disorders... - Effects of Hatha yoga and African dance on perceived stress, affect, and salivary cortisolJeremy West
Reed College, USA
Ann Behav Med 28:114-8. 2004..Dance and yoga have been shown to produce improvements in psychological well-being... - The validity of Beck Depression Inventory and Hamilton Rating Scale for Depression items in the assessment of depression among patients with multiple sclerosisPatricia J Moran
Osher Center for Integrative Medicine, University of California, San Francisco, California 94143 1726, USA
J Behav Med 28:35-41. 2005..Thus, the present data support the inclusion of all BDI items when measuring depression in MS. Decisions on whether or not to use all HRSD items or only the 12 shown here to capture depression may depend on the study purpose and design... - Depression and cortisol responses to psychological stress: a meta-analysisHeather M Burke
Department of Psychiatry, University of California, San Francisco, USA
Psychoneuroendocrinology 30:846-56. 2005..This blunted reactivity-impaired recovery pattern observed among the afternoon studies was most pronounced in studies with older and more severely depressed patients... - Treatment for depression and its relationship to improvement in quality of life and psychological well-being in multiple sclerosis patientsStacey Hart
University of California, San Francisco, VA Medical Center, CA 94121, USA
Qual Life Res 14:695-703. 2005..001), and self-acceptance (R2 = 0.26, p < 0.001). Findings suggest treating depression influences both the negative and positive aspects of QOL and underscore the importance of examining QOL with two complementary approaches... - Cognitive predictors of response to treatment for depression in multiple sclerosisLaura J Julian
Department of Medicine, University of California, CA, USA
J Neuropsychiatry Clin Neurosci 18:356-63. 2006..These results provide preliminary evidence to suggest that performance on neuropsychological measures may predict antidepressant treatment response in multiple sclerosis... - Familiarity, ambivalence, and firm reputation: is corporate fame a double-edged sword?Margaret E Brooks
Department of Psychology, Bowling Green State University, Bowling Green, OH 43403, USA
J Appl Psychol 88:904-14. 2003..The notion that people can simultaneously hold contradictory images of well-known firms may help to explain the inconsistent findings on the relation between familiarity and reputation... - Personality trait inferences about organizations: development of a measure and assessment of construct validityJerel E Slaughter
Department of Management and Policy, University of Arizona, Tucson, AZ 85721, USA
J Appl Psychol 89:85-103. 2004..Finally, results of a 4th study suggest that the measure is sensitive to experimental manipulations of organizational descriptions. Implications and suggestions for the use of this measure in future research are discussed... - The role of stress-response systems for the pathogenesis and progression of MSStefan M Gold
Multiple Sclerosis Program, Department of Neurology and Cousins Center for Psychoneuroimmunology, Neuropsychiatric Institute, UCLA School of Medicine, NRB1 (Rm 479, 635 Charles E. Young Drive South, Los Angeles, CA 90095, USA
Trends Immunol 26:644-52. 2005..Here, we integrate findings from molecular, cellular, experimental, clinical and epidemiological research to describe the involvement of stress response systems in MS pathogenesis and progression... - Teamwork culture and patient satisfaction in hospitalsMark Meterko
Management Decision and Research Center, VA Boston Healthcare System, Boston, Massachusetts, USA
Med Care 42:492-8. 2004.... - The unique impact of changes in normal appearing brain tissue on cognitive dysfunction in secondary progressive multiple sclerosis patientsDarcy Cox
Department of Neurology, University of California, San Francisco, CA, USA
Mult Scler 10:626-9. 2004..00, P = 0.98). NAA/Cr was not significantly related to cognitive functioning. CONCLUSIONS: Cognitive dysfunction may act as a clinical marker of normal appearing brain tissue pathology in multiple sclerosis... - Determination and documentation of the need for practice guidelinesCynthia A Sturm
American Psychological Association, 750 First Street, NE, Washington, DC 20002-4242, USA
Am Psychol 60:976-8. 2005