Shyam Mohapatra

Summary

Affiliation: University of South Florida
Country: USA

Publications

  1. ncbi request reprint ERK-1/2 activity is required for efficient RSV infection
    Xiaoyuan Kong
    The Joy McCann Culverhouse Airways Disease Research Center, Division of Allergy and Immunology, Department of Internal Medicine, MDC 19, 12901 Bruce B Downs Blvd, Tampa, FL 33612, USA
    FEBS Lett 559:33-8. 2004
  2. ncbi request reprint Thiolated chitosan/DNA nanocomplexes exhibit enhanced and sustained gene delivery
    Dongwon Lee
    Department of Internal Medicine, University of South Florida College of Medicine and James A Haley Veteran s Hospital, 12901 Bruce B Downs Blvd, Tampa, Florida 33612, USA
    Pharm Res 24:157-67. 2007
  3. pmc Regulating the Regulators: microRNA and Asthma
    Jia Wang Wang
    Department of Internal Medicine Division of Translational Medicine and Nanomedicine Research Center1, and Division of Allergy and Immunology2, Department of Molecular Medicine3, University of South Florida College of Medicine, and James A Haley VA Hospital and Medical Research Center4, Tampa, FL 33612
    World Allergy Organ J 4:94-103. 2011
  4. pmc Respiratory syncytial virus infection: from biology to therapy: a perspective
    Shyam S Mohapatra
    From the Joy McCann Culverhouse Airway Disease Research Center, Department of Internal Medicine, University of South Florida College of Medicine and the James A Haley VA Medical Center, Tampa, FL
    World Allergy Organ J 1:21-8. 2008
  5. pmc New perspectives on central and peripheral immune responses to acute traumatic brain injury
    Mahasweta Das
    Nanomedicine Research Center, University of South Florida Morsani College of Medicine, 12901 Bruce B Downs Blvd, Tampa, FL 33612, USA
    J Neuroinflammation 9:236. 2012
  6. pmc Modulation of lung inflammation by vessel dilator in a mouse model of allergic asthma
    Xiaoqin Wang
    Division of Allergy and Immunology, University of South Florida, Tampa, FL 33612, USA
    Respir Res 10:66. 2009
  7. pmc Natriuretic peptide receptor a as a novel target for prostate cancer
    Xiaoqin Wang
    Department of Molecular Medicine, University of South Florida, Tampa, FL 33612, USA
    Mol Cancer 10:56. 2011
  8. pmc Chitosan Interferon-gamma Nanogene Therapy for Lung Disease: Modulation of T-Cell and Dendritic Cell Immune Responses
    Xiaoyuan Kong
    Division of Allergy and Immunology, Culverhouse Airway Disease Research and Nanomedicine Center, University of South Florida College of Medicine, Tampa, FL
    Allergy Asthma Clin Immunol 4:95-105. 2008
  9. pmc Immunotherapy for allergies and asthma: present and future
    Shyam S Mohapatra
    Department of Internal Medicine, Division of Allergy and Immunology, University of South Florida College of Medicine, Tampa, FL, USA
    Curr Opin Pharmacol 10:276-88. 2010
  10. pmc Epidemiologic, experimental, and clinical links between respiratory syncytial virus infection and asthma
    Shyam S Mohapatra
    Department of Internal Medicine, Division of Allergy and Immunology, University of South Florida College of Medicine, James A Haley Veterans Hospital, 12901 Bruce B Downs Blvd, Tampa, Florida 33612, USA
    Clin Microbiol Rev 21:495-504. 2008

Collaborators

  • R F Lockey
  • Gary R Hellermann
  • Xiaoyuan Kong
  • Jian Zhang
  • Rajeswari Singam
  • Dong Won Lee
  • Xiaoqin Wang
  • H Yang
  • David L Vesely
  • Hiroto Matsuse
  • William R Gower
  • Xu Li
  • Shau Ku Huang
  • Mark Larché
  • Arun Kumar
  • Weidong Zhang
  • Mahasweta Das
  • Mukesh Kumar
  • Aruna K Behera
  • Jia Wang Wang
  • Sumita Behera
  • Natalie Frey Huls
  • Tina Brar
  • Sandhya Boyapalle
  • Terianne Wong
  • Shawna A Shirley
  • Homero San-Juan-Vergara
  • Monroe J King
  • M Ravi Kumar
  • Hariharan Srikanth
  • Manh Huong Phan
  • Pritish Mukherjee
  • Srinivas Nagaraj
  • Leslie Patrick
  • Xueqin Cao
  • Dawn Vo
  • Wenshi Wang
  • Keith R Pennypacker
  • Kunyu Li
  • Leigh Nattkemper
  • Saniya Rangooni
  • Christopher C Leonardo
  • Don F Cameron
  • Dongqing Chen
  • Mark Glaum
  • Seungjoo Park
  • Nagwa el-Badri
  • Edward Haller
  • Prasanna K Jena
  • Alison J Montpetit
  • Bishwabhusan Sahoo
  • Alison Montpetit
  • Homero San Juan-Vergara
  • Mark E Peeples
  • Samuel C Bukantz
  • Sharon Phillips
  • Tomas Tamulis
  • Cristina Perez De La Cruz
  • Li Chen Chen
  • Kam W Leong
  • Guraman Bhullar

Detail Information

Publications45

  1. ncbi request reprint ERK-1/2 activity is required for efficient RSV infection
    Xiaoyuan Kong
    The Joy McCann Culverhouse Airways Disease Research Center, Division of Allergy and Immunology, Department of Internal Medicine, MDC 19, 12901 Bruce B Downs Blvd, Tampa, FL 33612, USA
    FEBS Lett 559:33-8. 2004
    ..Inhibition of ERK pathways significantly decreases RSV infection of these cells compared to controls. These results demonstrate that the activation of the ERK-1/2 is required in RSV-induced early gene expression...
  2. ncbi request reprint Thiolated chitosan/DNA nanocomplexes exhibit enhanced and sustained gene delivery
    Dongwon Lee
    Department of Internal Medicine, University of South Florida College of Medicine and James A Haley Veteran s Hospital, 12901 Bruce B Downs Blvd, Tampa, Florida 33612, USA
    Pharm Res 24:157-67. 2007
    ..Herein, we report on a highly effective gene delivery system utilizing a 33-kDa thiol-modified chitosan derivative...
  3. pmc Regulating the Regulators: microRNA and Asthma
    Jia Wang Wang
    Department of Internal Medicine Division of Translational Medicine and Nanomedicine Research Center1, and Division of Allergy and Immunology2, Department of Molecular Medicine3, University of South Florida College of Medicine, and James A Haley VA Hospital and Medical Research Center4, Tampa, FL 33612
    World Allergy Organ J 4:94-103. 2011
    ..Profiling circulating miRNA might provide the highest specificity and sensitivity to diagnose asthma; similarly, correcting potential defects in the miRNA regulation network may lead to new therapeutic modalities to treat this disease...
  4. pmc Respiratory syncytial virus infection: from biology to therapy: a perspective
    Shyam S Mohapatra
    From the Joy McCann Culverhouse Airway Disease Research Center, Department of Internal Medicine, University of South Florida College of Medicine and the James A Haley VA Medical Center, Tampa, FL
    World Allergy Organ J 1:21-8. 2008
    ..The most recent data supporting the advantages and limitations of each of these approaches are discussed in detail. Several promising strategies offer hope for safe and effective prophylaxis and treatment of RSV infection...
  5. pmc New perspectives on central and peripheral immune responses to acute traumatic brain injury
    Mahasweta Das
    Nanomedicine Research Center, University of South Florida Morsani College of Medicine, 12901 Bruce B Downs Blvd, Tampa, FL 33612, USA
    J Neuroinflammation 9:236. 2012
    ....
  6. pmc Modulation of lung inflammation by vessel dilator in a mouse model of allergic asthma
    Xiaoqin Wang
    Division of Allergy and Immunology, University of South Florida, Tampa, FL 33612, USA
    Respir Res 10:66. 2009
    ..In this report, we evaluated the effects of vessel dilator (VD), another N-terminal natriuretic peptide covering amino acids 31-67 of proANF, on acute lung inflammation in a mouse model of allergic asthma...
  7. pmc Natriuretic peptide receptor a as a novel target for prostate cancer
    Xiaoqin Wang
    Department of Molecular Medicine, University of South Florida, Tampa, FL 33612, USA
    Mol Cancer 10:56. 2011
    ..However, the direct role of NPRA signaling in prostate cancer remains unclear...
  8. pmc Chitosan Interferon-gamma Nanogene Therapy for Lung Disease: Modulation of T-Cell and Dendritic Cell Immune Responses
    Xiaoyuan Kong
    Division of Allergy and Immunology, Culverhouse Airway Disease Research and Nanomedicine Center, University of South Florida College of Medicine, Tampa, FL
    Allergy Asthma Clin Immunol 4:95-105. 2008
    ..CIN therapy results in a reduction in proinflammatory CD8+ T cells and decreases the number and antigen-presenting activity of dendritic cells...
  9. pmc Immunotherapy for allergies and asthma: present and future
    Shyam S Mohapatra
    Department of Internal Medicine, Division of Allergy and Immunology, University of South Florida College of Medicine, Tampa, FL, USA
    Curr Opin Pharmacol 10:276-88. 2010
    ..This review discusses the pros and cons of recent developments in both currently practiced and experimental IT approaches...
  10. pmc Epidemiologic, experimental, and clinical links between respiratory syncytial virus infection and asthma
    Shyam S Mohapatra
    Department of Internal Medicine, Division of Allergy and Immunology, University of South Florida College of Medicine, James A Haley Veterans Hospital, 12901 Bruce B Downs Blvd, Tampa, Florida 33612, USA
    Clin Microbiol Rev 21:495-504. 2008
    ..Studies to date demonstrate that there is a significant association between RSV infection and childhood asthma and that preventing severe primary RSV infections can decrease the risk of childhood asthma...
  11. pmc Plasmid-encoded NP73-102 modulates atrial natriuretic peptide receptor signaling and plays a critical role in inducing tolerogenic dendritic cells
    Weidong Zhang
    Department of Internal Medicine, Division of Allergy and Immunology, University of South Florida College of Medicine, Tampa, FL 33612, USA
    Genet Vaccines Ther 9:3. 2011
    ..abstract:..
  12. pmc Lateral fluid percussion injury of the brain induces CCL20 inflammatory chemokine expression in rats
    Mahasweta Das
    Department of Internal Medicine, University of South Florida College of Medicine, 12901 Bruce B Downs Blvd, Tampa, FL 33612, USA
    J Neuroinflammation 8:148. 2011
    ..Due to the high incidence of head trauma in the sports field, battlefield and automobile accidents identification of the molecular signals involved in TBI progression is critical for the development of novel therapeutics...
  13. ncbi request reprint Intranasal gene transfer by chitosan-DNA nanospheres protects BALB/c mice against acute respiratory syncytial virus infection
    Mukesh Kumar
    Division of Allergy and Immunology Joy McCann Culverhouse Airway Disease Center, James A Haley Veterans Administration Hospital and University of South Florida College of Medicine, Tampa, FL 33612, USA
    Hum Gene Ther 13:1415-25. 2002
    ..Together, these results demonstrate the potential of IGT against acute RSV infection...
  14. ncbi request reprint Intranasal IL-12 produces discreet pulmonary and systemic effects on allergic inflammation and airway reactivity
    Hiroto Matsuse
    Department of Internal Medicine, Joy McCann Culverhouse Airway Disease Research Center, Tampa, FL 33612, USA
    Int Immunopharmacol 3:457-68. 2003
    ..Thus, intranasal delivery of IL-12 may provide an approach for the treatment of asthma and may be useful as an adjuvant in local nasal immunotherapy (IT) and in asthma...
  15. ncbi request reprint Adenovirus-mediated interferon gamma gene therapy for allergic asthma: involvement of interleukin 12 and STAT4 signaling
    Aruna K Behera
    Division of Allergy and Immunology, Joy McCann Culverhouse Airway Disease Center, University of South Florida College of Medicine, Tampa, FL 33620, USA
    Hum Gene Ther 13:1697-709. 2002
    ..Thus, these results demonstrate that mucosal Ad-IFN-gamma gene transfer can effectively attenuate established allergen-induced airway inflammation and AHR, predominantly through an IL-12- and STAT4-dependent mechanism...
  16. ncbi request reprint Role of natriuretic peptide signaling in modulating asthma and inflammation
    Shyam S Mohapatra
    Division of Allergy and Immunology JMC Airway Disease Research Center, Department of Internal Medicine, University of South Florida and VA Hospital, Tampa, FL 33612, USA
    Can J Physiol Pharmacol 85:754-9. 2007
    ..This report will review and critically evaluate the role of the ANP pathway in asthma and inflammation...
  17. pmc Thiolated chitosan nanoparticles enhance anti-inflammatory effects of intranasally delivered theophylline
    Dong Won Lee
    Division of Allergy and Immunology and Joy McCann Culverhouse Airway Disease Center, Department of Internal Medicine, University of South Florida College of Medicine and James A, Haley Veteran s Hospital, Tampa, FL 33612, USA
    Respir Res 7:112. 2006
    ..It was hypothesized that adsorption of theophylline to chitosan nanoparticles modified by the addition of thiol groups would improve theophylline absorption by the bronchial epithelium and enhance its anti-inflammatory effects...
  18. ncbi request reprint Respiratory syncytial virus: immunopathology and control
    Weidong Zhang
    Division of Allergy and Immunology, Department of Internal Medicine, College of Medicine, University of South Florida, 12901 Bruce B Downs Blvd, Tampa, FL 33612, USA
    Expert Rev Clin Immunol 2:169-79. 2006
    ..In this review, the biology of RSV infection, its immunopathology, the role of innate and adaptive immunity, as well as the understanding of how to control RSV infection based on prophylactic and therapeutic approaches are discussed...
  19. pmc Combined fluticasone propionate and salmeterol reduces RSV infection more effectively than either of them alone in allergen-sensitized mice
    Rajeswari Singam
    Division of Allergy and Immunology, Joy McCann Culverhouse Airway Disease Research Center, University of South Florida College of Medicine and James A, Haley VA Hospital, Tampa, FL, USA
    Virol J 3:32. 2006
    ..Respiratory syncytial virus (RSV) infection is the major cause of bronchiolitis in infants and is a risk factor for the development of asthma. Allergic asthmatics are more susceptible to RSV infection and viral exacerbation...
  20. ncbi request reprint Immunobiology of grass pollen allergens
    Shyam S Mohapatra
    Department of Internal Medicine, Division of Allergy and Immunology and the James A Haley Veterans Hospital, University of South Florida, College of Medicine, 12901 Bruce B Downs Boulevard, Tampa, FL 33612, USA
    Curr Allergy Asthma Rep 5:381-7. 2005
    ..This review is focused on the structure and immunobiology of the grass allergens and highlights how recent advances in the field have contributed to superior diagnosis and immunotherapy for allergy to grass pollens...
  21. pmc An immunocompromised BALB/c mouse model for respiratory syncytial virus infection
    Xiaoyuan Kong
    Department of Internal Medicine, Division of Allergy and Immunology, Joy McCann Culverhouse Airway Disease Research Center, University of South Florida College of Medicine, USA
    Virol J 2:3. 2005
    ..BALB/c mice were treated with cyclophosphamide (CYP) and five days later, they were infected with RSV intranasally. Pulmonary RSV titers, inflammation and airway hyperresponsiveness were measured five days after infection...
  22. ncbi request reprint Mucosal gene expression vaccine: a novel vaccine strategy for respiratory syncytial virus
    Shyam S Mohapatra
    Dept of Internal Medicine, Div of Allergy and Immunology, Joy McCann Culverhouse Airway Disease Research Center, University of South Florida College of Medicine VA Hospital, 12901 Bruce B Downs Boulevard, Tampa, FL 33612, USA
    Pediatr Infect Dis J 22:S100-3; discussion S103-4. 2003
    ..MGXV-treated mice show no significant change in airway reactivity to methacholine and no apparent pulmonary inflammation. Together these results demonstrate the potential of MGXV against acute RSV infection...
  23. pmc Mechanism of cigarette smoke condensate-induced acute inflammatory response in human bronchial epithelial cells
    Gary R Hellermann
    Division of Allergy and Immunology, Joy McCann Culverhouse Airway Disease Center, Department of Internal Medicine, University of South Florida College of Medicine, VA Hospital, Tampa 33612, USA
    Respir Res 3:22. 2002
    ..To demonstrate the involvement of tobacco smoking in the pathophysiology of lung disease, the responses of pulmonary epithelial cells to cigarette smoke condensate (CSC) - the particulate fraction of tobacco smoke - were examined...
  24. ncbi request reprint Natriuretic peptides and genesis of asthma: an emerging paradigm?
    Shyam S Mohapatra
    Division of Allergy and Immunology JMC Airway Disease Research Center, University of South Florida, Tampa, FL 33612, USA
    J Allergy Clin Immunol 114:520-6. 2004
    ..Thus natriuretic peptides appear to play a pivotal role in the genesis and control of asthma, and they might provide an important target to modulate allergen-induced immune responses in allergic patients...
  25. ncbi request reprint American Academy of Allergy, Asthma and Immunology--60th annual meeting. Advances in allergy and asthma therapy: 2003 AAAI updates. 7-12 March 2003, Denver, CO, USA
    Shyam S Mohapatra
    University of South Florida, Division of Allergy and Immunology, Tampa, FL 33612, USA
    IDrugs 6:423-5. 2003
  26. ncbi request reprint Inhibition of respiratory syncytial virus infection with intranasal siRNA nanoparticles targeting the viral NS1 gene
    Weidong Zhang
    Division of Allergy and Immunology Joy McCann Culverhouse Airway Disease Research Center, Department of Internal Medicine, University of South Florida, MDC 19 Rm 2536, 12901 Bruce B Downs Boulevard, Tampa, Florida 33612, USA
    Nat Med 11:56-62. 2005
    ..Thus, siNS1 nanoparticles may provide an effective inhibition of RSV infection in humans...
  27. ncbi request reprint Weed pollen allergens
    Shyam S Mohapatra
    University of South Florida College of Medicine, James A Haley Veterans Hospital, Tampa, Florida, USA
    Clin Allergy Immunol 18:207-22. 2004
  28. pmc Transverse susceptibility as a biosensor for detection of Au-Fe₃O₄ nanoparticle-embedded human embryonic kidney cells
    Natalie Frey Huls
    Department of Physics, University of South Florida, Tampa, FL 33620, USA
    Sensors (Basel) 13:8490-500. 2013
    ..While the highest concentration of Au-Fe3O4 nanoparticles (1 mg/mL) was found to give the strongest TS signal, it is notable that the TS signal of the nanoparticles could still be detected at concentrations as low as 0.1 mg/mL. ..
  29. pmc Nanotechnology Applications to HIV Vaccines and Microbicides
    Sandhya Boyapalle
    Department of Internal Medicine, University of South Florida Morsani College of Medicine, Tampa, FL
    J Glob Infect Dis 4:62-8. 2012
    ..Thus far nanoparticles provide a strong platform to combine protein and DNA based vaccines/microbicides and will facilitate the production, preclinical evaluation and clinical testing in the future...
  30. pmc Initial observations of cell-mediated drug delivery to the deep lung
    Arun Kumar
    Department of Internal Medicine, University of South Florida College of Medicine, Tampa, 33612, USA
    Cell Transplant 20:609-18. 2011
    ....
  31. pmc Multifunctional magnetic nanoparticles for targeted delivery
    Arun Kumar
    Division of Allergy and Immunology, Department of Internal Medicine, University of South Florida, Tampa, Florida, USA
    Nanomedicine 6:64-9. 2010
    ..The authors demonstrate that a simple external magnetic field is sufficient to target a drug to specific sites in the body without the need for functionalized nanoparticles, at least in selected organs and diseases...
  32. pmc Microbes and asthma: the missing cellular and molecular links
    Tina Brar
    Division of Translational Medicine, Department of Internal Medicine, University of South Florida College of Medicine, Tampa, FL 33612, USA
    Curr Opin Pulm Med 18:14-22. 2012
    ....
  33. pmc The infectious march: the complex interaction between microbes and the immune system in asthma
    Terianne Wong
    Department of Molecular Medicine, University of South Florida College of Medicine, Bruce B Downs Boulevard, Tampa, FL 33612, USA
    Immunol Allergy Clin North Am 30:453-80, v. 2010
    ....
  34. ncbi request reprint Respiratory syncytial virus infection activates STAT signaling in human epithelial cells
    Xiaoyuan Kong
    Division of Allergy and Immunology, The Joy McCann Culverhouse Airway Disease Center, Department of Internal Medicine, University of South Florida College of Medicine, Tampa, FL 33612, USA
    Biochem Biophys Res Commun 306:616-22. 2003
    ..RSV also activated STAT-3 and IL-6 specific antibodies blocked this activation. Thus, activation of the STAT-1alpha and STAT-3 pathways play a role in RSV infection...
  35. doi request reprint Natriuretic peptide receptor a as a novel anticancer target
    Xiaoyuan Kong
    Joy McCann Culverhouse Airway Disease and Nanomedicine Research Center, Allergy and Immunology Division, Department of Internal Medicine, University of South Florida College of Medicine, Tampa, FL 33612, USA
    Cancer Res 68:249-56. 2008
    ..These results suggest that NPRA is involved in tumor angiogenesis and represents a new target for cancer therapy...
  36. ncbi request reprint Mechanism of bronchoprotective effects of a novel natriuretic hormone peptide
    Gary Hellermann
    Department of Internal Medicine, University of South Florida College of Medicine, Tampa, FL 33612, USA
    J Allergy Clin Immunol 113:79-85. 2004
    ..Recently, another plasmid-encoded C-terminal peptide, pNHP(73-102), was shown to induce a long-lasting bronchoprotective effect in a mouse model of allergic asthma...
  37. ncbi request reprint 2'-5' Oligoadenylate synthetase plays a critical role in interferon-gamma inhibition of respiratory syncytial virus infection of human epithelial cells
    Aruna K Behera
    Division of Allergy and Immunology, Joy McCann Culverhouse Airway Disease Center, University of South Florida College of Medicine and James A Haley Veterans Affairs Hospital, Tampa 33612, USA
    J Biol Chem 277:25601-8. 2002
    ..These results provide direct evidence of the involvement of 2-5 AS in IFN-gamma-mediated antiviral activity in these cells...
  38. doi request reprint Chitosan nanoparticle-mediated gene transfer
    Dongwon Lee
    College of Medicine, Department of Internal Medicine, University of South Florida, Tampa, FL, USA
    Methods Mol Biol 433:127-40. 2008
    ..Chitosan has been reported to form nanocomplexes with DNA to protect them against DNase degradation and transfer DNA effectively and safely into cells in culture cell as well as in vivo...
  39. pmc Protein kinase C-alpha activity is required for respiratory syncytial virus fusion to human bronchial epithelial cells
    Homero San-Juan-Vergara
    The Joy McCann Culverhouse Airways Disease Research Center, Division of Allergy and Immunology, Department of Internal Medicine, College of Medicine, University of South Florida, Tampa, FL 33612, USA
    J Virol 78:13717-26. 2004
    ..Also, PKC-alpha colocalizes with virus particles and is required for RSV fusion to the cell membrane. Thus, PKC-alpha could provide a new pharmacological target for controlling RSV infection...
  40. ncbi request reprint Serum total IgE and specific IgE to Dermatophagoides pteronyssinus, but not eosinophil cationic protein, are more likely to be elevated in elderly asthmatic patients
    Monroe J King
    Joy McCann Culverhouse Airway Disease Center, University of South Florida, Tampa, Florida 33612, USA
    Allergy Asthma Proc 25:321-5. 2004
    ..4 microg/L, Pharmacia Diagnostics). The serum of elderly asthmatic patients is more likely to have elevated total IgE and a positive specific IgE to Dp. ECP is elevated in elderly subjects but is not an indicator of asthma...
  41. pmc Curcumin prevents human dendritic cell response to immune stimulants
    Shawna A Shirley
    Department of Molecular Medicine, College of Medicine, University of South Florida, Tampa, FL 33612, USA
    Biochem Biophys Res Commun 374:431-6. 2008
    ..These data suggest a therapeutic role for curcumin as an immune suppressant...
  42. ncbi request reprint Development of hyaluronic acid-Fe2O3 hybrid magnetic nanoparticles for targeted delivery of peptides
    Arun Kumar
    Division of Allergy and Immunology, Department of Internal Medicine, College of Medicine, University of South Florida, Tampa, Florida 33612, USA
    Nanomedicine 3:132-7. 2007
    ..Results show that these particles delivered peptides at about 100% level. These HA-iron oxide nanoparticles are expected to be useful in developing effective tissue and cell targeting systems...
  43. ncbi request reprint Atrial natriuretic peptide gene transfer by means of intranasal administration attenuates airway reactivity in a mouse model of allergic sensitization
    Mukesh Kumar
    Division of Allergy and Immunology Joy McCann Culverhouse Airway Disease Center, University of South Florida College of Medicine and James A Haley Veteran s Hospital, Tampa 33612, USA
    J Allergy Clin Immunol 110:879-82. 2002
    ..Mice administered pANP demonstrated significantly less AHR for 20 days after treatment. The results demonstrate that pANP gene transfer protects against AHR and might be useful in the treatment of asthma...
  44. ncbi request reprint Nanoparticle-mediated gene delivery: state of the art
    M Ravi Kumar
    Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, SASNagar, Mohali, India
    Expert Opin Biol Ther 4:1213-24. 2004
    ....
  45. ncbi request reprint Modifying allergens and using adjuvants for specific immunotherapy
    Mark Larché
    Imperial College London Faculty of Medicine, London, England
    Clin Allergy Immunol 18:641-61. 2004

Research Grants8

  1. Chliposome IFN-gamma-pDNA Naoparticle Therapy for Asthma
    Shyam Mohapatra; Fiscal Year: 2004
    ..The results of the proposed research are expected to advance our knowledge of the mechanisms of asthma and may lead to the development of an effective approach for the prevention and/or treatment of asthma. ..
  2. Chlipoplex Nanoparticle Prophylactics for RSV Infection
    Shyam Mohapatra; Fiscal Year: 2004
    ..abstract_text> ..
  3. Chitosan IFNgamma-pDNA Nanosphere Therapy and Immunopathology of Allergic Asthma
    Shyam Mohapatra; Fiscal Year: 2006
    ..It is anticipated that the results of these studies will contribute significantly to our knowledge of asthma and CIN therapy may provide a major breakthrough in management of asthma. ..
  4. An Integrated Nano-Cell Delivery Platform of Theranostics for Lung Cancers
    Subhra Mohapatra; Fiscal Year: 2010
    ....