Research Topics
| J G ModrallSummaryAffiliation: University of Texas Southwestern Medical Center Country: USA Publications
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Publications
Transient advanced mental impairment: an underappreciated morbidity after aortic surgeryScott F Rosen
Division of Vascular Surgery, University of Texas Southwestern Medical Center, Dallas 75390-9157, USA
J Vasc Surg 35:376-81. 2002..8). CONCLUSIONS: These data show that TAMI is prevalent among patients undergoing aortic reconstruction and is associated with dramatically increased morbidity and postoperative hospitalization rates...
ANG II type 1 receptor downregulation does not require receptor endocytosis or G protein couplingJ G Modrall
Department of Surgery, Dallas Veterans Affairs Medical Center and the University of Texas Southwestern Medical Center, Dallas, Texas 75235, USA
Am J Physiol Cell Physiol 281:C801-9. 2001..These data suggest that coupling to G(q) is required for the later phase (2-24 h) of AT(1) receptor downregulation...
Late incidence of chronic venous insufficiency after deep vein harvestJ Gregory Modrall
Division of Vascular and Endovascular Surgery, Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX 75390 9157, USA
J Vasc Surg 46:520-5; discussion 525. 2007..The purpose of this study was to define the late incidence of chronic venous insufficiency (CVI) and to characterize the long-term alterations in venous physiology after DV harvest...
Operative mortality for renal artery bypass in the United States: Results from the National Inpatient SampleJ Gregory Modrall
Division of Vascular and Endovascular Surgery, Department of Surgery, University of Texas Southwestern Medical Center, and Dallas Veterans Affairs Medical Center, Dallas, TX, USA
J Vasc Surg 48:317-322. 2008..The purpose of this study was to define the operative mortality rate for RABG in the United States and to identify risk factors for perioperative mortality...
Predictors of outcome for renal artery stenting performed for salvage of renal functionJ Gregory Modrall
Dallas Veterans Affairs Medical Center, Dallas, TX, USA
J Vasc Surg 54:1414-1421.e1; discussion 1420-1. 2011..To identify preoperative clinical features that predict a durable improvement in renal function with renal artery stenting (RAS)...
Deep vein harvest: predicting need for fasciotomyJ Gregory Modrall
Department of Surgery, University of Texas Southwestern Medical Center and Dallas Veterans Affairs Medical Center, Dallas, TX 75390 9157, USA
J Vasc Surg 39:387-94. 2004..The purpose of this study was to define the frequency of fasciotomy in patients undergoing deep vein harvest and to identify clinical predictors of the need for fasciotomy after deep vein harvest...
Comparison of superficial femoral vein and saphenous vein as conduits for mesenteric arterial bypassJ Gregory Modrall
Division of Vascular Surgery, Department of Surgery, University of Texas Southwestern Medical Center, TX 75390 9157, USA
J Vasc Surg 37:362-6. 2003..The purpose of this study was to compare the outcomes of SV and SFV for mesenteric arterial bypass...
Effect of hospital volume on in-hospital mortality for renal artery bypassJ Gregory Modrall
Department of Surgery, Division of Vascular and Endovascular Surgery, University of Texas Southwestern Medical Center, Dallas Veterans Affairs Medical Center, Dallas, Texas 75390, USA
Vasc Endovascular Surg 43:339-45. 2009..A recent report determined that the nationwide mortality for renal artery bypass (RAB) is surprisingly high-10%. We hypothesized that operative mortality for RAB is related to the volume of such operations performed in each center...
Depletion of tissue angiotensin-converting enzyme differentially influences the intrarenal and urinary expression of angiotensin peptidesJ Gregory Modrall
Department of Surgery, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9157, USA
Hypertension 43:849-53. 2004..Sustained intrarenal levels of angiotensin-(1-7) may contribute to chronic hypotension and polyuria in tisACE-/- mice, particularly in the context of depleted angiotensin II in the kidney...
Superficial femoral-popliteal vein as a conduit for brachiocephalic arterial reconstructionsJ Gregory Modrall
Division of Vascular Surgery, Department of Surgery, University of Texas Southwestern Medical Center, Dallas 75390 9157, USA
Ann Vasc Surg 16:17-23. 2002..Assisted primary patency was 100%. These data suggest that SFPV is a safe, durable conduit for brachiocephalic reconstructions. SFPV yielded excellent results for a disadvantaged patient population...
Clinical and kidney morphologic predictors of outcome for renal artery stenting: data to inform patient selectionJ Gregory Modrall
Dallas Veterans Affairs Medical Center, University of Texas Southwestern Medical Center, Dallas, TX 75390 9157, USA
J Vasc Surg 53:1282-89; discussion 1289-90. 2011..The purpose of the current study was to identify clinical and kidney morphologic features that predict a favorable blood pressure (BP) response to renal artery stenting (RAS)...
Emerging role of endovascular grafts in complex aortoiliac occlusive diseaseAhsan T Ali
Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA
J Vasc Surg 38:486-91. 2003..This endovascular technique can be a viable alternative to conventional surgical revascularization in patients with advanced aortoiliac occlusive disease at high risk...
The limitations of thoracic endovascular aortic repair in altering the natural history of blunt aortic injuryJennifer L Lang
Division of Vascular Surgery, Department of Surgery, The University of Texas Southwestern Medical Center, Dallas, Tex 75390 9031, USA
J Vasc Surg 52:290-7; discussion 297. 2010..Thoracic endovascular aortic repair (TEVAR) is accepted treatment for blunt aortic injury (BAI). We hypothesized that immediate TEVAR would reduce deaths from aortic rupture in patients with BAI...
Open-cell versus closed-cell stent design differences in blood flow velocities after carotid stentingDamon S Pierce
Division of Vascular and Endovascular Surgery, Department of Surgery, Veterans Affairs North Texas Health Care System and the University of Texas Southwestern Medical Center, Dallas, TX 75390 9157, USA
J Vasc Surg 49:602-6; discussion 606. 2009..To identify possible stent design differences in carotid velocities, we analyzed DUS studies obtained before and immediately after carotid artery stenting (CAS)...
Utility and accuracy of duplex ultrasonography in evaluating in-stent restenosis after carotid stentingTodd Cumbie
Division of Vascular and Endovascular Surgery, Department of Surgery, University of Texas Southwestern Medical Center and Dallas Veterans Affairs Medical Center, Dallas, TX, USA
Am J Surg 196:623-8. 2008..Stents alter flow velocities after carotid artery stenting (CAS). To identify criteria for in-stent restenosis (ISR), velocities obtained by duplex ultrasonography (DU) after CAS were analyzed...
Angiotensin II exerts positive feedback on the intrarenal renin-angiotensin system by an angiotensin converting enzyme-dependent mechanismJavid Sadjadi
Department of Surgery, Division of Vascular Surgery, Dallas Veterans Affairs Medical Center and the University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA
J Surg Res 129:272-7. 2005..This study tested the hypothesis that an incremental increase in plasma ANG II induces the intrarenal renin-angiotensin system (RAS) in the non-ischemic kidney by an angiotensin converting enzyme (ACE) dependent mechanism...
Femorofemoral bypass with femoral popliteal veinAhsan Ali
University of Texas Southwestern Medical Center, Dallas, 75390, USA
J Vasc Surg 42:35-9. 2005..CONCLUSIONS: FFBP performed with FPV has excellent 1-, 3, and 5-year patency rates. FPV has sustained patency for FFBP in patients with poor runoff...
Endovascular repair of small abdominal aortic aneurysms: a paradigm shift?M Burress Welborn
Division of Vascular Surgery, Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX 75390 9157, USA
Vasc Endovascular Surg 39:381-91. 2005..The poor outcomes following the treatment of large AAAs is thought to be due to complex anatomy. EVAR of less anatomically challenging small AAAs may improve long-term outcomes...
Arterial reconstruction of infected femoral artery pseudoaneurysms using superficial femoral-popliteal veinChristopher L Bell
Department of Surgery, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75235, USA
J Am Coll Surg 200:831-6. 2005..CONCLUSIONS: Excision of IFAP with revascularization can be successfully achieved using SFPV. This method may prove to be superior to other methods with apparent higher patency rates and resistance to reinfection...
Trends and outcomes of concurrent carotid revascularization and coronary bypassCarlos H Timaran
Division of Vascular and Endovascular Surgery, Department of Surgery, University of Texas Southwestern Medical Center, Dallas, Tex, USA
J Vasc Surg 48:355-360; discussion 360-1. 2008..This study was undertaken to evaluate the nationwide trends and outcomes of CAS before CABG vs combined CEA and CABG and to assess the risk for adverse events...
Influence of age, aneurysm size, and patient fitness on suitability for endovascular aortic aneurysm repairCarlos H Timaran
Division of Vascular and Endovascular Surgery, Department of Surgery, University of Texas Southwestern Medical Center, and Dallas Veterans Affairs Medical Center, Dallas, Texas 75390 9157, USA
Ann Vasc Surg 22:730-5. 2008..Conversely, suitability has not significantly changed for small AAAs. Overall, EVAR suitability is not influenced by age, aneurysm size, or patient fitness...
Intracranial hemorrhage after carotid endarterectomy and carotid stenting in the United States in 2005Carlos H Timaran
Division of Vascular and Endovascular Surgery, Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX 75390 9157, USA
J Vasc Surg 49:623-8; discussion 628-9. 2009..The effect of more intense dual antiplatelet therapy required for CAS on the frequency of ICH has not been established. This study was undertaken to evaluate the nationwide occurrence of ICH associated with CAS vs CEA...
Accuracy and utility of three-dimensional contrast-enhanced magnetic resonance angiography in planning carotid stentingCarlos H Timaran
Division of Vascular and Endovascular Surgery, Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX 75390 9157, USA
J Vasc Surg 46:257-63; discussion 263-4. 2007..This study assessed the accuracy of three-dimensional CE-MRA as a noninvasive screening tool, compared with digital subtraction angiography (DSA), for evaluating carotid and arch morphology before CAS...
Device and imaging-specific volumetric analysis of clot lysis after percutaneous mechanical thrombectomy for iliofemoral DVTErin H Murphy
University of Texas Southwestern Medical Center, Dallas, Texas 75390 9157, USA
J Endovasc Ther 17:423-33. 2010..To determine the most accurate method of assessing clot lysis after percutaneous mechanical thrombectomy for iliofemoral deep vein thrombosis (DVT) and to evaluate the effectiveness of two different pharmacomechanical thrombectomy devices...
Atherosclerotic plaque composition assessed by virtual histology intravascular ultrasound and cerebral embolization after carotid stentingCarlos H Timaran
Division of Vascular and Endovascular Surgery, Department of Surgery, Veterans Affairs North Texas Health Care System, University of Texas Southwestern Medical Center, Dallas, TX 75390 9157, USA
J Vasc Surg 52:1188-94. 2010..The purpose of this study was to assess the relationship between atherosclerotic plaque composition determined with VH-IVUS and the occurrence of cerebral embolization after carotid artery stenting (CAS)...
Aortofemoral bypass in young patients with premature atherosclerosis: is superficial femoral vein superior to Dacron?Mark R Jackson
Department of Surgery, University of Texas Southwestern Medical Center, Dallas, USA
J Vasc Surg 40:17-23. 2004....
Endovascular aortic aneurysm repair in patients with the highest risk and in-hospital mortality in the United StatesCarlos H Timaran
Division of Vascular and Endovascular Surgery, Department of Surgery, University of Texas Southwestern Medical Center, 5909 Harry Hines Boulevard, Dallas, TX 75390 9157, USA
Arch Surg 142:520-4; discussion 524-5. 2007..This finding was predominantly caused by the substantial in-hospital mortality after EVAR (9%)...
Effects of ethnicity and insurance status on outcomes after thoracic endoluminal aortic aneurysm repair (TEVAR)Erin H Murphy
Division of Vascular Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA
J Vasc Surg 51:14S-20S. 2010..This study was designed to better characterize TEVAR outcomes in a large population, and to determine if outcomes are independently influenced by patient ethnicity and insurance status...
Transmetatarsal amputation: assessment of current selection criteriaThomas Anthony
Section of General Surgery, Surgical Service, VA North Texas Health Care System, 4500 S Lancaster Rd, Dallas, TX 75216, USA
Am J Surg 192:e8-11. 2006..The purpose of this study was to assess the validity of these selection criteria...
Hand ischemia after radial artery cannulationR James Valentine
Division of Vascular Surgery, Department of Surgery, The University of Texas Southwestern Medical Center, Dallas, TX 75390-9031, USA
J Am Coll Surg 201:18-22. 2005..Nonoperative therapy with vasodilators can be equally effective in treating cannula-induced radial artery injuries in some patients...
Gender differences in blood flow velocities after carotid angioplasty and stentingCarlos H Timaran
University of Texas Southwestern Medical Center, Dallas, TX75390 9157, USA
Ann Vasc Surg 21:576-9. 2007..Our data indicate that similar criteria should be used after CAS for interpreting carotid velocity profiles in both women and men...
Aggressive percutaneous mechanical thrombectomy of deep venous thrombosis: early clinical resultsFrank R Arko
Division of Vascular and Endovascular Surgery, The University of Texas Southwestern Medical Center, 5909 Harry Hines Boulevard, Dallas, TX 75903, USA
Arch Surg 142:513-8; discussion 518-9. 2007..To evaluate percutaneous mechanical thrombectomy for deep venous thrombosis (DVT)...
Pharmacotherapy before and after revascularization: anticoagulation, antiplatelet agents, and statinsNabil N Dagher
Division of Vascular and Endovascular Surgery, Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX 75235 9157, USA
Semin Vasc Surg 20:10-4. 2007..Proper adjunctive pharmacotherapy for the patient with PAD has the potential to improve symptoms, graft patency, and survival in this challenging subset of patients...
Correlation between ankle-brachial index, symptoms, and health-related quality of life in patients with peripheral vascular diseaseJoshua Long
Department of Surgery, University of Texas Southwestern Medical Center, USA
J Vasc Surg 39:723-7. 2004..However, neither variable fully expresses patient HRQL. These data suggest that sole reliance on these surrogates may not accurately reflect the effect of PVD on HRQL, or the potential benefit of vascular surgery in improving HRQL...
Upregulation of autocrine-paracrine renin-angiotensin systems in chronic renovascular hypertensionJavid Sadjadi
Division of Vascular Surgery and the Department of Surgery, Dallas Veterans Affairs Medical Center, and the University of Texas Southwestern Medical Center-Dallas, TX, USA
J Vasc Surg 36:386-92. 2002....
The clinical course of new-onset atrial fibrillation after elective aortic operationsR J Valentine
Department of Surgery, The University of Texas Southwestern Medical Center, Dallas 75390-9157, USA
J Am Coll Surg 193:499-504. 2001..AFIB does not affect the outcomes of aortic operations. Most patients will revert spontaneously to normal sinus rhythm and do not require longterm anticoagulation to prevent thromboembolic complications...
Device-specific aneurysm sac morphology after endovascular aneurysm repair: evaluation of contemporary graft materialsHarshal S Broker
University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
J Vasc Surg 47:702-6; discussion 707. 2008..This study analyzed device-specific aneurysm sac morphology after endovascular aneurysm repair (EVAR) with low-permeability devices...
Do preoperative finger pressures predict early arterial steal in hemodialysis access patients? A prospective analysisR James Valentine
Division of Vascular Surgery, Department of Surgery, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
J Vasc Surg 36:351-6. 2002..The purpose of this study was to determine whether plethysmographically derived finger pressures (FPs) or digital-brachial indices (DBIs) are predictive of symptomatic arterial steal...
Long-term results of the treatment of aortic graft infection by in situ replacement with femoral popliteal vein graftsAhsan T Ali
Division of Vascular Surgery, Department of Surgery, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
J Vasc Surg 50:30-9. 2009..The goal of this study was to evaluate long-term outcomes in large cohort of consecutive patients treated with NAIS for AGI...
Ocular findings as predictors of carotid artery occlusive disease: is carotid imaging justified?Heath K McCullough
Department of Surgery, University of Texas Southwestern Medical Center, Dallas, 75390, USA
J Vasc Surg 40:279-86. 2004..However, the predictive value of ocular findings for the presence of CAOD is controversial. The purpose of this study was to define the predictive value of ocular symptoms and ophthalmologic examination in identifying significant CAOD...
Computed tomographic angiography has added value in patients with vascular diseaseJennifer L McDougal
Division of Vascular Surgery, Department of Surgery, The University of Texas Southwestern Medical Center, Dallas, Texas 75390-9031, USA
J Vasc Surg 44:998-1001. 2006..Vascular surgeons need to ensure adequate follow-up for their patients with potentially serious extravascular lesions...
Graft-associated hemorrhage from femoropopliteal vein graftsAhsan T Ali
University of Arkansas Medical Center Division of Vascular and Endovascular Surgery, USA
J Vasc Surg 42:667-72. 2005..Strategies for prevention and alternative treatment modalities are appropriate in patients at high risk for GAH...
Novel aspects of the renal renin-angiotensin system: angiotensin-(1-7), ACE2 and blood pressure regulationMark C Chappell
The Hypertension and Vascular Disease Center, Wake Forest University School of Medicine, Winston-Salem, NC 27015, USA
Contrib Nephrol 143:77-89. 2004
AT1 receptor mutant lacking heterotrimeric G protein coupling activates the Src-Ras-ERK pathway without nuclear translocation of ERKsKoichi Seta
Cardiovascular Research Institute, Department of Cell Biology and Molecular Medicine, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, New Jersey 07103, USA
J Biol Chem 277:9268-77. 2002..These results suggest that heterotrimeric G protein-dependent and -independent signaling mechanisms play distinct roles in Ang II-mediated cellular responses...
Time of day is associated with postoperative morbidity: an analysis of the national surgical quality improvement program dataJ Gregory Modrall
Ann Surg 248:500-1; author reply 501. 2008
