Ron Mittler

Summary

Affiliation: University of Nevada
Country: USA

Publications

  1. ncbi request reprint Abiotic stress, the field environment and stress combination
    Ron Mittler
    Department of Biochemistry and Molecular Biology, University of Nevada, Mail Stop 200, Reno, NV 89557, USA
    Trends Plant Sci 11:15-9. 2006
  2. pmc Enhanced tolerance to oxidative stress in transgenic Arabidopsis plants expressing proteins of unknown function
    Song Luhua
    Department of Biochemistry and Molecular Biology, University of Nevada, Reno Nevada 89557, USA
    Plant Physiol 148:280-92. 2008
  3. doi request reprint Reactive oxygen species homeostasis and signalling during drought and salinity stresses
    Gad Miller
    Department of Biochemistry and Molecular Biology, University of Nevada, Reno, 89557, USA
    Plant Cell Environ 33:453-67. 2010
  4. pmc Could heat shock transcription factors function as hydrogen peroxide sensors in plants?
    Gad Miller
    Department of Biochemistry and Molecular Biology, University of Nevada, Mail Stop 200, Reno, NV 89557, USA
    Ann Bot 98:279-88. 2006
  5. ncbi request reprint Signals from chloroplasts converge to regulate nuclear gene expression
    Shai Koussevitzky
    Howard Hughes Medical Institute, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA
    Science 316:715-9. 2007
  6. pmc Gain- and loss-of-function mutations in Zat10 enhance the tolerance of plants to abiotic stress
    Ron Mittler
    Department of Biochemistry, University of Nevada, Reno, NV 89557, USA
    FEBS Lett 580:6537-42. 2006
  7. doi request reprint Genetic engineering for modern agriculture: challenges and perspectives
    Ron Mittler
    Department of Biochemistry and Molecular Biology, University of Nevada, Reno, Nevada 89557, USA
    Annu Rev Plant Biol 61:443-62. 2010
  8. ncbi request reprint Reactive oxygen gene network of plants
    Ron Mittler
    Department of Biochemistry, Mail Stop 200, University of Nevada, Reno, NV 89557, USA
    Trends Plant Sci 9:490-8. 2004
  9. pmc Double mutants deficient in cytosolic and thylakoid ascorbate peroxidase reveal a complex mode of interaction between reactive oxygen species, plant development, and response to abiotic stresses
    Gad Miller
    Department of Biochemistry and Molecular Biology, University of Nevada, Reno, Nevada 89557, USA
    Plant Physiol 144:1777-85. 2007
  10. doi request reprint The plant NADPH oxidase RBOHD mediates rapid systemic signaling in response to diverse stimuli
    Gad Miller
    Department of Biochemistry and Molecular Biology, University of Nevada, Reno, 89557, USA
    Sci Signal 2:ra45. 2009

Collaborators

Detail Information

Publications39

  1. ncbi request reprint Abiotic stress, the field environment and stress combination
    Ron Mittler
    Department of Biochemistry and Molecular Biology, University of Nevada, Mail Stop 200, Reno, NV 89557, USA
    Trends Plant Sci 11:15-9. 2006
    ....
  2. pmc Enhanced tolerance to oxidative stress in transgenic Arabidopsis plants expressing proteins of unknown function
    Song Luhua
    Department of Biochemistry and Molecular Biology, University of Nevada, Reno Nevada 89557, USA
    Plant Physiol 148:280-92. 2008
    ..Our findings suggest that tolerance to oxidative stress involves mechanisms and pathways that are unknown at present, including some that are specific to Arabidopsis or the Brassicaceae...
  3. doi request reprint Reactive oxygen species homeostasis and signalling during drought and salinity stresses
    Gad Miller
    Department of Biochemistry and Molecular Biology, University of Nevada, Reno, 89557, USA
    Plant Cell Environ 33:453-67. 2010
    ....
  4. pmc Could heat shock transcription factors function as hydrogen peroxide sensors in plants?
    Gad Miller
    Department of Biochemistry and Molecular Biology, University of Nevada, Mail Stop 200, Reno, NV 89557, USA
    Ann Bot 98:279-88. 2006
    ....
  5. ncbi request reprint Signals from chloroplasts converge to regulate nuclear gene expression
    Shai Koussevitzky
    Howard Hughes Medical Institute, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA
    Science 316:715-9. 2007
    ..We propose a model in which multiple indicators of aberrant plastid function in Arabidopsis are integrated upstream of GUN1 within plastids, which leads to ABI4-mediated repression of nuclear-encoded genes...
  6. pmc Gain- and loss-of-function mutations in Zat10 enhance the tolerance of plants to abiotic stress
    Ron Mittler
    Department of Biochemistry, University of Nevada, Reno, NV 89557, USA
    FEBS Lett 580:6537-42. 2006
    ..Surprisingly, knockout and RNAi mutants of Zat10 were also more tolerant to osmotic and salinity stress. Our results suggest that Zat10 plays a key role as both a positive and a negative regulator of plant defenses...
  7. doi request reprint Genetic engineering for modern agriculture: challenges and perspectives
    Ron Mittler
    Department of Biochemistry and Molecular Biology, University of Nevada, Reno, Nevada 89557, USA
    Annu Rev Plant Biol 61:443-62. 2010
    ....
  8. ncbi request reprint Reactive oxygen gene network of plants
    Ron Mittler
    Department of Biochemistry, Mail Stop 200, University of Nevada, Reno, NV 89557, USA
    Trends Plant Sci 9:490-8. 2004
  9. pmc Double mutants deficient in cytosolic and thylakoid ascorbate peroxidase reveal a complex mode of interaction between reactive oxygen species, plant development, and response to abiotic stresses
    Gad Miller
    Department of Biochemistry and Molecular Biology, University of Nevada, Reno, Nevada 89557, USA
    Plant Physiol 144:1777-85. 2007
    ....
  10. doi request reprint The plant NADPH oxidase RBOHD mediates rapid systemic signaling in response to diverse stimuli
    Gad Miller
    Department of Biochemistry and Molecular Biology, University of Nevada, Reno, 89557, USA
    Sci Signal 2:ra45. 2009
    ..Our results reveal the profound role that ROS play in mediating rapid, long-distance, cell-to-cell propagating signals in plants...
  11. pmc Ascorbate peroxidase 1 plays a key role in the response of Arabidopsis thaliana to stress combination
    Shai Koussevitzky
    Department of Biochemistry and Molecular Biology, University of Nevada, Reno, Nevada 89557, USA
    J Biol Chem 283:34197-203. 2008
    ..Our findings suggest that cytosolic APX1 plays a key role in the acclimation of plants to a combination of drought and heat stress...
  12. pmc Enhanced tolerance to environmental stress in transgenic plants expressing the transcriptional coactivator multiprotein bridging factor 1c
    Nobuhiro Suzuki
    Department of Biochemistry and Molecular Biology, University of Nevada, Reno, NE 89557, USA
    Plant Physiol 139:1313-22. 2005
    ..Present findings suggest that MBF1 proteins could be used to enhance the tolerance of plants to different abiotic stresses...
  13. pmc The zinc-finger protein Zat12 plays a central role in reactive oxygen and abiotic stress signaling in Arabidopsis
    Sholpan Davletova
    Department of Biochemistry and Molecular Biology, University of Nevada, Reno, 89557, USA
    Plant Physiol 139:847-56. 2005
    ..Our results suggest that Zat12 plays a central role in reactive oxygen and abiotic stress signaling in Arabidopsis...
  14. doi request reprint The transcriptional co-activator MBF1c is a key regulator of thermotolerance in Arabidopsis thaliana
    Nobuhiro Suzuki
    Department of Biochemistry and Molecular Biology, University of Nevada, Reno, NV 89557, USA
    J Biol Chem 283:9269-75. 2008
    ..Our results provide evidence for the existence of a tightly coordinated heat stress-response network, involving trehalose-, SA-, and ethylene-signaling pathways, that is under the control of MBF1c...
  15. pmc Thiamin confers enhanced tolerance to oxidative stress in Arabidopsis
    Meral Tunc-Ozdemir
    Department of Biochemistry and Molecular Biology, University of Nevada, Reno, Nevada 89557, USA
    Plant Physiol 151:421-32. 2009
    ..Taken together, our studies suggest that thiamin and TPP function as important stress-response molecules that alleviate oxidative stress during different abiotic stress conditions...
  16. ncbi request reprint The EAR-motif of the Cys2/His2-type zinc finger protein Zat7 plays a key role in the defense response of Arabidopsis to salinity stress
    Sultan Ciftci-Yilmaz
    Department of Biochemistry and Molecular Biology, University of Nevada, Reno, Nevada 89557, USA
    J Biol Chem 282:9260-8. 2007
    ..Our findings demonstrate that the EAR-domain of Cys2/His2-type zinc finger proteins plays a key role in the defense response of Arabidopsis to abiotic stresses...
  17. doi request reprint Proteomic profiling of tandem affinity purified 14-3-3 protein complexes in Arabidopsis thaliana
    Ing Feng Chang
    Department of Biochemistry and Molecular Biology, University of Nevada, Reno, NV, USA
    Proteomics 9:2967-85. 2009
    ..More than 80% (101) of these putative clients represent previously unidentified 14-3-3 interactors. These results raise the number of putative 14-3-3 clients identified in plants to over 300...
  18. pmc A cyclic nucleotide-gated channel (CNGC16) in pollen is critical for stress tolerance in pollen reproductive development
    Meral Tunc-Ozdemir
    Department of Biochemistry, University of Nevada, Reno, Nevada 89557, USA
    Plant Physiol 161:1010-20. 2013
    ....
  19. doi request reprint Reactive oxygen signaling and abiotic stress
    Gad Miller
    Department of Biochemistry and Molecular Biology, University of Nevada, MS200, Reno, NV 89557, USA
    Physiol Plant 133:481-9. 2008
    ..Here, we describe our recent findings and discuss how ROS integrate different signals originating from different cellular compartments during abiotic stress...
  20. pmc Cytosolic ascorbate peroxidase 1 is a central component of the reactive oxygen gene network of Arabidopsis
    Sholpan Davletova
    Department of Biochemistry and Molecular Biology, University of Nevada, Reno, Nevada 89557, USA
    Plant Cell 17:268-81. 2005
    ..Our study points to a key role for the cytosol in protecting the chloroplast during light stress and provides evidence for cross-compartment protection of thylakoid and stromal/mitochondrial APXs by cytosolic APX1...
  21. pmc What makes species unique? The contribution of proteins with obscure features
    Martin Gollery
    Department of Biochemistry and Molecular Biology, University of Nevada, Reno, NV 89557, USA
    Genome Biol 7:R57. 2006
    ....
  22. doi request reprint Charting plant interactomes: possibilities and challenges
    Mustafa Morsy
    Department of Biochemistry and Molecular Biology, MS200, University of Nevada, Reno, NV 89557, USA
    Trends Plant Sci 13:183-91. 2008
    ..Bioinformatics approaches for curating and assessing the confidence of these datasets through inter-species comparisons will be crucial in achieving a complete understanding of protein interaction networks in plants...
  23. ncbi request reprint Oxidative stress, antioxidants and stress tolerance
    Ron Mittler
    Dept of Botany, Plant Sciences Institute, 353 Bessey Hall, Iowa State University, Ames, IA 50011, USA
    Trends Plant Sci 7:405-10. 2002
    ..These raise several intriguing questions about the relationships between ROI signaling, ROI stress and the production and scavenging of ROIs in the different cellular compartments...
  24. ncbi request reprint Molecular and biochemical mechanisms associated with dormancy and drought tolerance in the desert legume Retama raetam
    Lilach Pnueli
    Department of Biology, Technion Israel Institute of Technology, Technion City, Haifa 32000, Israel
    Plant J 31:319-30. 2002
    ..raetam and its acclimation to the desert ecosystem. These may enable plants to withstand long periods of drought, as well as rapidly to exit dormancy upon rainfall...
  25. pmc The combined effect of drought stress and heat shock on gene expression in tobacco
    Ludmila Rizhsky
    Department of Biology, Technion Israel Institute of Technology, Technion City, Haifa 32000, Israel
    Plant Physiol 130:1143-51. 2002
    ..Therefore, improving stress tolerance of plants and crops may require a reevaluation, taking into account the effect of multiple stresses on plant metabolism and defense...
  26. ncbi request reprint Growth suppression, altered stomatal responses, and augmented induction of heat shock proteins in cytosolic ascorbate peroxidase (Apx1)-deficient Arabidopsis plants
    Lilach Pnueli
    Department of Biology, Technion Israel Institute of Technology, Technion City, Haifa 32000, Israel
    Plant J 34:187-203. 2003
    ..Our findings also suggest that at least part of the induction of heat shock proteins during light stress in Arabidopsis is mediated by H2O2 that is scavenged by APX1...
  27. ncbi request reprint The water-water cycle is essential for chloroplast protection in the absence of stress
    Ludmila Rizhsky
    Department of Biology, Technion Israel Institute of Technology, Technion City, Haifa 32000, Israel
    J Biol Chem 278:38921-5. 2003
    ..Our studies provide genetic evidence for the importance of the water-water cycle in protecting the photosynthetic apparatus of higher plants from photooxidative damage...
  28. pmc Unraveling the tapestry of networks involving reactive oxygen species in plants
    Frank Van Breusegem
    Department of Plant Systems Biology, Flanders Institute for Biotechnology, Belgium
    Plant Physiol 147:978-84. 2008
  29. ncbi request reprint Double antisense plants lacking ascorbate peroxidase and catalase are less sensitive to oxidative stress than single antisense plants lacking ascorbate peroxidase or catalase
    Ludmila Rizhsky
    Department of Biology, Technion Israel Institute of Technology, Technion City, Haifa 32000, Israel
    Plant J 32:329-42. 2002
    ..In addition, our findings demonstrate that the plant genome has a high degree of plasticity and will respond differently to different stressful conditions, namely, lack of APX, lack of CAT, or lack of both APX and CAT...
  30. ncbi request reprint Mechanism of cell death and disease resistance induction by transgenic expression of bacterio-opsin
    Dominique Pontier
    Biotech Center, Foran Hall, 59 Dudley Road, Rutgers State University of New Jersey, New Brunswick, NJ 08903, USA
    Plant J 30:499-509. 2002
    ..Our work provides direct molecular evidence to support a working model in which alterations in ionic homeostasis at the level of the PM may work as one of the critical steps in the signalling pathway for the activation of the HR...
  31. pmc When defense pathways collide. The response of Arabidopsis to a combination of drought and heat stress
    Ludmila Rizhsky
    Department of Biology, Technion, Israel Institute of Technology, Technion City, Haifa 32000, Israel
    Plant Physiol 134:1683-96. 2004
    ..Our results highlight the plasticity of the plant genome and demonstrate its ability to respond to complex environmental conditions that occur in the field...
  32. ncbi request reprint Reactive oxygen intermediates and glutathione regulate the expression of cytosolic ascorbate peroxidase during iron-mediated oxidative stress in bean
    Irena Pekker
    Department of Botany, Faculty of Agriculture, Hebrew University of Jerusalem, Rehovot, Israel
    Plant Mol Biol 49:429-38. 2002
    ..We further show, using cAPX-antisense transgenic plants, that cAPX expression is essential to prevent iron-mediated tissue damage in tobacco...
  33. pmc Transcriptomic footprints disclose specificity of reactive oxygen species signaling in Arabidopsis
    Ilya Gadjev
    Department of Plant Systems Biology, Flanders Interuniversity Institute for Biotechnology, Ghent University, B 9052 Gent, Belgium
    Plant Physiol 141:436-45. 2006
    ..Our analysis provides a framework that will assist future efforts to address the impact of ROS signals within environmental stress conditions and elucidate the molecular mechanisms of the oxidative stress response in plants...
  34. pmc Annotating genes of known and unknown function by large-scale coexpression analysis
    Kevin Horan
    Department of Botany and Plant Sciences, University of California, Riverside, CA 92521, USA
    Plant Physiol 147:41-57. 2008
    ..Finally, the public Plant Gene Expression Database (http://bioweb.ucr.edu/PED) was developed as part of this project to provide efficient access and mining tools for the vast gene expression data of this study...
  35. ncbi request reprint POFs: what we don't know can hurt us
    Martin Gollery
    TimeLogic a Division of Active Motif, Incline Village, NV 89451, USA
    Trends Plant Sci 12:492-6. 2007
    ..Furthermore, with respect to many species-specific features, such studies show that we seem to be limited in what we can expect to learn from a model plant such as Arabidopsis...
  36. pmc Delayed leaf senescence induces extreme drought tolerance in a flowering plant
    Rosa M Rivero
    Department of Plant Sciences, University of California, Davis, CA 95616, USA
    Proc Natl Acad Sci U S A 104:19631-6. 2007
    ..The production of drought-tolerant crops able to grow under restricted water regimes without diminution of yield would minimize drought-related losses and ensure food production in water-limited lands...
  37. ncbi request reprint The zinc finger protein Zat12 is required for cytosolic ascorbate peroxidase 1 expression during oxidative stress in Arabidopsis
    Ludmila Rizhsky
    Department of Botany, Plant Sciences Institute, Iowa State University, Ames, Iowa 50011, USA
    J Biol Chem 279:11736-43. 2004
    ..Our results suggest that Zat12 is an important component of the oxidative stress response signal transduction network of Arabidopsis required for Zat7, WRKY25, and Apx1 expression during oxidative stress...
  38. doi request reprint Metabolomics for plant stress response
    Vladimir Shulaev
    Virginia Bioinformatics Institute, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA
    Physiol Plant 132:199-208. 2008
    ..We will describe approaches such as metabolic profiling and metabolic fingerprinting as well as combination of different 'omics' platforms to achieve a holistic view of the plant response stress and conduct detailed pathway analysis...
  39. pmc The roles of reactive oxygen species in plant cells
    Julia Bailey-Serres
    Plant Physiol 141:311. 2006