Michael J Minzenberg

Summary

Affiliation: University of California
Country: USA

Publications

  1. doi request reprint A neurocognitive model of borderline personality disorder: effects of childhood sexual abuse and relationship to adult social attachment disturbance
    Michael J Minzenberg
    University of California, Sacramento, CA 95817, USA
    Dev Psychopathol 20:341-68. 2008
  2. pmc Diminished orientation-specific surround suppression of visual processing in schizophrenia
    Jong H Yoon
    Department of Psychiatry and Imaging Research Center, University of California Davis, 4701 X Street, Sacramento, CA 95817, USA
    Schizophr Bull 35:1078-84. 2009
  3. pmc Prefrontal cortical deficits and impaired cognition-emotion interactions in schizophrenia
    Stefan Ursu
    Department of Psychiatry and Behavioral Sciences, School of Medicine, University of California, Davis, Sacramento, CA 95817, USA
    Am J Psychiatry 168:276-85. 2011
  4. pmc Modafinil modulation of the default mode network
    Michael J Minzenberg
    Department of Psychiatry, University of California, Davis School of Medicine, Sacramento, CA, USA
    Psychopharmacology (Berl) 215:23-31. 2011
  5. pmc Multivariate pattern analysis of functional magnetic resonance imaging data reveals deficits in distributed representations in schizophrenia
    Jong H Yoon
    Department of Psychiatry and Imaging Research Center, University of California Davis, Sacramento, California 95817, USA
    Biol Psychiatry 64:1035-41. 2008
  6. pmc Impaired prefrontal-basal ganglia functional connectivity and substantia nigra hyperactivity in schizophrenia
    Jong H Yoon
    Department of Psychiatry and Imaging Research Center, University of California Davis, Sacramento, CA 95817, USA
    Biol Psychiatry 74:122-9. 2013
  7. ncbi request reprint Social-emotion recognition in borderline personality disorder
    Michael J Minzenberg
    University of California, Davis Medical Center, Sacramento, CA 95817, USA
    Compr Psychiatry 47:468-74. 2006
  8. pmc Gamma oscillatory power is impaired during cognitive control independent of medication status in first-episode schizophrenia
    Michael J Minzenberg
    Department of Psychiatry, University of California, Davis School of Medicine, Sacramento, CA 95817, USA
    Neuropsychopharmacology 35:2590-9. 2010
  9. ncbi request reprint Modafinil augments oscillatory power in middle frequencies during rule selection
    Michael J Minzenberg
    Department of Psychiatry, University of California, San Francisco School of Medicine, San Francisco, California, USA San Francisco Veterans Affairs Medical Center, San Francisco, California, USA
    Psychophysiology 51:510-9. 2014
  10. doi request reprint Excessive contralateral motor overflow in schizophrenia measured by fMRI
    Michael J Minzenberg
    Department of Psychiatry, University of California, Davis School of Medicine, Sacramento, CA, USA
    Psychiatry Res 202:38-45. 2012

Detail Information

Publications31

  1. doi request reprint A neurocognitive model of borderline personality disorder: effects of childhood sexual abuse and relationship to adult social attachment disturbance
    Michael J Minzenberg
    University of California, Sacramento, CA 95817, USA
    Dev Psychopathol 20:341-68. 2008
    ....
  2. pmc Diminished orientation-specific surround suppression of visual processing in schizophrenia
    Jong H Yoon
    Department of Psychiatry and Imaging Research Center, University of California Davis, 4701 X Street, Sacramento, CA 95817, USA
    Schizophr Bull 35:1078-84. 2009
    ..In conjunction with physiological and anatomical evidence from basic and postmortem studies, our results suggest a deficit of inhibition in primary visual cortex in schizophrenia...
  3. pmc Prefrontal cortical deficits and impaired cognition-emotion interactions in schizophrenia
    Stefan Ursu
    Department of Psychiatry and Behavioral Sciences, School of Medicine, University of California, Davis, Sacramento, CA 95817, USA
    Am J Psychiatry 168:276-85. 2011
    ....
  4. pmc Modafinil modulation of the default mode network
    Michael J Minzenberg
    Department of Psychiatry, University of California, Davis School of Medicine, Sacramento, CA, USA
    Psychopharmacology (Berl) 215:23-31. 2011
    ..How this network is modulated by neurochemical systems during functional brain activity is not yet understood...
  5. pmc Multivariate pattern analysis of functional magnetic resonance imaging data reveals deficits in distributed representations in schizophrenia
    Jong H Yoon
    Department of Psychiatry and Imaging Research Center, University of California Davis, Sacramento, California 95817, USA
    Biol Psychiatry 64:1035-41. 2008
    ..We applied this method to test the hypothesis of the impairment in distributed representations in schizophrenia. We also compared the results of this method with traditional general linear model (GLM)-based univariate analysis...
  6. pmc Impaired prefrontal-basal ganglia functional connectivity and substantia nigra hyperactivity in schizophrenia
    Jong H Yoon
    Department of Psychiatry and Imaging Research Center, University of California Davis, Sacramento, CA 95817, USA
    Biol Psychiatry 74:122-9. 2013
    ..We undertook this event-related functional magnetic resonance imaging study to test the hypothesis that PFC dysfunction is associated with altered function of and connectivity with dopamine regulating regions of the basal ganglia...
  7. ncbi request reprint Social-emotion recognition in borderline personality disorder
    Michael J Minzenberg
    University of California, Davis Medical Center, Sacramento, CA 95817, USA
    Compr Psychiatry 47:468-74. 2006
    ..These results suggest that patients with BPD have deficits in higher order integration of social information, which may be related to some of the more serious symptoms of the disorder...
  8. pmc Gamma oscillatory power is impaired during cognitive control independent of medication status in first-episode schizophrenia
    Michael J Minzenberg
    Department of Psychiatry, University of California, Davis School of Medicine, Sacramento, CA 95817, USA
    Neuropsychopharmacology 35:2590-9. 2010
    ..This suggests that altered local circuit function supporting high-frequency oscillatory activity in prefrontal cortex ensembles may serve as the pathophysiological substrate of cognitive control deficits in schizophrenia...
  9. ncbi request reprint Modafinil augments oscillatory power in middle frequencies during rule selection
    Michael J Minzenberg
    Department of Psychiatry, University of California, San Francisco School of Medicine, San Francisco, California, USA San Francisco Veterans Affairs Medical Center, San Francisco, California, USA
    Psychophysiology 51:510-9. 2014
    ..Augmentation of catecholamine signaling enhances middle-frequency cortical oscillatory power associated with rule selection, which may subserve diverse subcomponent processes in proactive cognitive control. ..
  10. doi request reprint Excessive contralateral motor overflow in schizophrenia measured by fMRI
    Michael J Minzenberg
    Department of Psychiatry, University of California, Davis School of Medicine, Sacramento, CA, USA
    Psychiatry Res 202:38-45. 2012
    ..This pathological motor overflow may be partly due to altered modulation of intended movement within the basal ganglia and premotor cortex...
  11. doi request reprint Developing treatments for impaired cognition in schizophrenia
    Michael J Minzenberg
    Department of Psychiatry and Center for Neuroscience, University of California Davis School of Medicine, Sacramento, CA 95817, USA
    Trends Cogn Sci 16:35-42. 2012
    ..Each of these approaches shows promise and their integration may optimize benefits for patients in the future...
  12. pmc GABA concentration is reduced in visual cortex in schizophrenia and correlates with orientation-specific surround suppression
    Jong H Yoon
    Department of Psychiatry and Imaging Research Center, University of California, Davis, Davis, California 95817, USA
    J Neurosci 30:3777-81. 2010
    ..10). These results suggest that a neocortical GABA deficit in subjects with schizophrenia leads to impaired cortical inhibition and that GABAergic synaptic transmission in visual cortex plays a critical role in OSSS...
  13. ncbi request reprint Modafinil shifts human locus coeruleus to low-tonic, high-phasic activity during functional MRI
    Michael J Minzenberg
    Department of Psychiatry, University of California, Davis School of Medicine, Sacramento, CA, USA
    Science 322:1700-2. 2008
    ..These results confirm in humans the role of the LC-NE system in PFC function and cognitive control and suggest a mechanism for therapeutic action of procognitive noradrenergic agents...
  14. pmc Cognitive control deficits in schizophrenia: mechanisms and meaning
    Tyler A Lesh
    Department of Psychiatry, UC Davis Imaging Research Center, Davis School of Medicine, University of California, Sacramento, CA 95817, USA
    Neuropsychopharmacology 36:316-38. 2011
    ..Finally, we discuss recent advances in the neuropharmacology of cognition and how they can inform a targeted approach to the development of effective therapies for this disabling aspect of schizophrenia...
  15. ncbi request reprint Adult social attachment disturbance is related to childhood maltreatment and current symptoms in borderline personality disorder
    Michael J Minzenberg
    University of California, Davis Medical Center, Sacramento, California 95817, USA
    J Nerv Ment Dis 194:341-8. 2006
    ....
  16. ncbi request reprint Reduced Self-Referential Source Memory Performance is Associated with Interpersonal Dysfunction in Borderline Personality Disorder
    Michael J Minzenberg
    University of California, Davis Medical Center, Sacramento, CA 95817, USA
    J Pers Disord 20:42-54. 2006
    ..Heterogeneity in source memory function may be specifically related to some of the hallmark interpersonal disturbances of BPD, independent of the effects of general negative affect or general memory impairment...
  17. doi request reprint A match made by modafinil: probability matching in choice decisions and spatial attention
    Joy J Geng
    Center for Mind and Brain, University of California, Davis, Davis, CA 95618, USA
    J Cogn Neurosci 25:657-69. 2013
    ..Together, these results suggest that enhancing cognitive control mechanisms (e.g., through prefrontal cortical function) leads spatial attention to follow choice decisions in selecting information according to rule-based expectations...
  18. pmc Meta-analysis of 41 functional neuroimaging studies of executive function in schizophrenia
    Michael J Minzenberg
    Department of Psychiatry, University of California Davis School of Medicine, Sacramento, CA 95817, USA
    Arch Gen Psychiatry 66:811-22. 2009
    ..Whether these impairments are properly considered reflective of hypofrontality vs hyperfrontality remains unresolved...
  19. pmc The cognitive neuroscience of memory function and dysfunction in schizophrenia
    Charan Ranganath
    Center for Neuroscience and Department of Psychology, University of California at Davis, Davis, CA 95618, USA
    Biol Psychiatry 64:18-25. 2008
    ..A brief summary of research on episodic memory in schizophrenia is presented to provide a context for investigating item-specific and relational memory processes. Candidate brain regions are also discussed...
  20. pmc Frontolimbic structural changes in borderline personality disorder
    Michael J Minzenberg
    Mount Sinai School of Medicine and Bronx VA Medical Center, Bronx, NY, USA
    J Psychiatr Res 42:727-33. 2008
    ..We tested the hypothesis that BPD patients exhibit gross structural changes that parallel the respective increases in amygdala activation and impairment of rostral/subgenual ACC activation...
  21. ncbi request reprint Modafinil: a review of neurochemical actions and effects on cognition
    Michael J Minzenberg
    Imaging Research Center, Davis School of Medicine, UC Davis Health System, University of California, Sacramento, CA 95817, USA
    Neuropsychopharmacology 33:1477-502. 2008
    ..These effects are in general advantageous for cognitive processes. Overall, modafinil is an excellent candidate agent for remediation of cognitive dysfunction in neuropsychiatric disorders...
  22. pmc Fronto-limbic dysfunction in response to facial emotion in borderline personality disorder: an event-related fMRI study
    Michael J Minzenberg
    Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    Psychiatry Res 155:231-43. 2007
    ..The neural substrates underlying processing of anger may also be altered. These changes may represent an expression of the volumetric and serotonergic deficits observed in these brain areas in BPD...
  23. pmc Pharmacotherapy for attention-deficit/hyperactivity disorder: from cells to circuits
    Michael J Minzenberg
    Department of Psychiatry, Davis School of Medicine, University of California, Sacramento, CA 95817, USA
    Neurotherapeutics 9:610-21. 2012
    ..This is a very active area of investigation at all phases of the translational cycle, and near-term work is poised to firmly link cellular neuropharmacology to large-scale effects, and point the way toward advances in treatment...
  24. doi request reprint An index of relative central α-adrenergic receptor antagonism by antipsychotic medications
    Michael J Minzenberg
    Department of Psychiatry, University of California, Davis School of Medicine, Sacramento, CA 95817, USA
    Exp Clin Psychopharmacol 19:31-9. 2011
    ..This index of HALα equivalents should facilitate the determination of the effects of α-adrenergic antagonism by these medications on clinical efficacy, side effects, and biological and cognitive measures of illness and treatment...
  25. pmc Association of dorsolateral prefrontal cortex dysfunction with disrupted coordinated brain activity in schizophrenia: relationship with impaired cognition, behavioral disorganization, and global function
    Jong H Yoon
    Department of Psychiatry and Imaging Research Center, University of California, Davis, Sacramento, Calif 95817, USA
    Am J Psychiatry 165:1006-14. 2008
    ....
  26. doi request reprint The quest for developing new treatments from imaging techniques: promises, problems and future potential
    Michael J Minzenberg
    University of California, Imaging Research Center, Davis School of Medicine, 4701 X Street, Sacramento, CA 95817, USA 1 916 734 7174 1 916 734 7850
    Expert Opin Drug Discov 2:1029-33. 2007
    ..The authors propose that pharmaco-fMRI is emerging as a major tool to enhance the drug development process in order to bring truly novel treatments to patients with a range of neuropsychiatric disorders...
  27. ncbi request reprint Semantic priming in schizophrenia: a review and synthesis
    Michael J Minzenberg
    Department of Psychiatry, University of California, San Francisco, USA
    J Int Neuropsychol Soc 8:699-720. 2002
    ..We also describe associations with other neurocognitive dysfunction, neurochemical and electrophysiological disturbances, and clinical manifestations (such as thought disorder)...
  28. ncbi request reprint The effects of guanfacine on context processing abnormalities in schizotypal personality disorder
    Margaret M McClure
    VA VISN3 Mental Illness Research, Education, and Clinical Center, Bronx, New York 10468, USA
    Biol Psychiatry 61:1157-60. 2007
    ..This study examined the potential of guanfacine for improving context processing, a feature of working memory, in SPD...
  29. ncbi request reprint Association of anticholinergic load with impairment of complex attention and memory in schizophrenia
    Michael J Minzenberg
    Department of Psychiatry, Mount Sinai School of Medicine and VA Medical Center, Bronx, NY, USA
    Am J Psychiatry 161:116-24. 2004
    ....
  30. ncbi request reprint Catechol-O-methyltransferase Val158Met genotype variation is associated with prefrontal-dependent task performance in schizotypal personality disorder patients and comparison groups
    Michael J Minzenberg
    Bronx Veterans Affairs Medical Center, Bronx, New York, 14068, USA
    Psychiatr Genet 16:117-24. 2006
    ..We evaluated the relationship of the COMT genotype with diagnostic status and cognitive performance in schizotypal personality disorder...
  31. ncbi request reprint Exaggerated affect-modulated startle during unpleasant stimuli in borderline personality disorder
    Erin A Hazlett
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 10029, USA
    Biol Psychiatry 62:250-5. 2007
    ..The affect-modulated startle response is a reliable indicator of emotional processing of stimuli. The aim of this study was to examine emotional processing in BPD patients (n = 27) and healthy control subjects (n = 21)...